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Oral Biology and Oral Pathology Commons

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Comorbidity Of Hypertension And Chronic Renal Failure And Their Impact On Oral Complications: A Cross-Sectional Study., Dalia Ghalwash, Sara Abdelwahed, Asmaa Abobakr 2023 The British University in Egypt

Comorbidity Of Hypertension And Chronic Renal Failure And Their Impact On Oral Complications: A Cross-Sectional Study., Dalia Ghalwash, Sara Abdelwahed, Asmaa Abobakr

Dentistry

The present study aimed to investigate the influence of both end-stage renal diseases (ESRD) and hypertension (HTN) on the various oral manifestations and periodontal condition, to evaluate and compare the oral manifestations and periodontal health status in hypertensive patients with ESRD versus control, and to explore any possible correlation of the oral findings with systemic disease status. This was a cross-sectional study which included two equal groups of patients, Group I were hypertensive patients with ESRD and Group II were hypertensive patients only. All patients were hypertensive and were on antihypertensive medications. Regarding the incidence of oral lesions in both …


Pharmacological Management Of Oral Lesion, TANISHKA TAORI, BHINIKA WADHER, SHEFALI MAHESHWARI, DR SWAPNIL MOHOD, DR SUWARNA DANGORE 2023 DATTA MEGHE INSTITUTE OF HIGHER EDUCATION AND RESEARCH, SAWANGI MEGHE,WARDHA, MAHARASHTRA, INDIA

Pharmacological Management Of Oral Lesion, Tanishka Taori, Bhinika Wadher, Shefali Maheshwari, Dr Swapnil Mohod, Dr Suwarna Dangore

International Arab Journal of Dentistry

Oral ulcerations caused by aphtous lesions, leukoplakia, scarlet fever, syphilis, NOMA, mucormycosis herpetic lesions, candidiasis, discoid lupus erythematous, ulcerative lichen planus, mucous membrane pemphigoid, spongy nevus, oral submoucs fibrosis and pemphigus vulgaris are treated in a step-up fashion that may include topical, intralesional, and systemic pharmaceutical treatment. This page discusses the most often used therapy agents, methods, and dosages. Although the emphasis is on local pharmacologic therapy, systemic illnesses that frequently occur with such oral lesions are briefly discussed, as is the appropriate care.


Enhancing Dental Aligners With Direct 3d Printing Manufacturing, Erin Clark, Lauren Ickes, Tyler Madison 2023 The University of Akron

Enhancing Dental Aligners With Direct 3d Printing Manufacturing, Erin Clark, Lauren Ickes, Tyler Madison

Williams Honors College, Honors Research Projects

Replacement of thermoforming with direct 3d printed aligners, molding appliances for dental and alveolar movement. Currently the process involved requires 3d printing models and plastic thermoforming, trimming and polishing to fabricate the end product. If possible a product that could be 3d printed that had stress retention, crack resistance, and stain resistance properties delivered in thickness between .030 and .040 inches.


Probing The Porphyromonas Gingivalis Nitrosative Stress Response Network, Alexandra Galina 2023 Virginia Commonwealth University

Probing The Porphyromonas Gingivalis Nitrosative Stress Response Network, Alexandra Galina

Theses and Dissertations

Objective: To persist in the oral cavity, the perio-pathogen Porphyromonas gingivalis must have an efficient nitrosative stress response mechanism. To better understand how P. gingivalis responds to nitrite (NO2-) we must determine what genes are involved in the nitrosative stress response network.

Methods: Through genomic screening, a list of genes was generated that were hypothesized to be part of the nitrosative stress response network and believed to be involved in nitrate/nitrite metabolism or redox state of the cells. Protein coding regions were replaced with the ermF sequence by allelic exchange mutagenesis. 15 mutants were created …


Stereomicroscopic Evaluation Of Dentinal Microcracks After Instrumentation Of Curved Canal With Rotary Files In Two Motions, Nupur Vasava, Shreya Modi, Chintan Joshi, Sweety Thumar, Anisha Parmar, Kruti Jadawala 2022 Karnavati School of Dentistry, Gandhinagar, Gujarat, India

Stereomicroscopic Evaluation Of Dentinal Microcracks After Instrumentation Of Curved Canal With Rotary Files In Two Motions, Nupur Vasava, Shreya Modi, Chintan Joshi, Sweety Thumar, Anisha Parmar, Kruti Jadawala

Journal of Dentistry Indonesia

Objective: This study aimed to examine the effects of three distinct file systems with two motion types—rotary and reciprocation—on the development of dentinal microcracks after root canal preparation using a stereomicroscope. Methods: Sixty mandibular molars with a curvature of 30° were decoronated and divided into three groups (Vortex Blue, Mtwo, and ProTaper Next) and two subgroups (rotary and reciprocating motions). The samples were then instrumented with the files, dyed with 1% methylene blue dye, and sectioned horizontally at 3, 6, and 9 mm from the root apex. The dentinal microcracks were inspected using a stereomicroscope at 40× magnification. One-way analysis …


Evaluation Of Dentoskeletal And Pharyngeal Airway Changes After Treatment With Twin Block And Monoblock Appliance In Growing Patients, Esra Genc, Ahmet Karaman, Gülşah Püskül 2022 Department of Orthodontics, Faculty of Dentistry, Istanbul Aydın University, Istanbul, Turkey

Evaluation Of Dentoskeletal And Pharyngeal Airway Changes After Treatment With Twin Block And Monoblock Appliance In Growing Patients, Esra Genc, Ahmet Karaman, Gülşah Püskül

Journal of Dentistry Indonesia

Objective: To compare of pharyngeal airway dimensions and dentoskeletal changes after treatment with twin block (TWB) and monoblock (MB) appliance in growing patients. Methods: The sample was comprised of a total of 72 patients at the ages of 10 to 13. The TWB group consisted of 36 patients (22 females, 14 males, mean age: 11.9±1.5) and MB group consisted of 36 patients (18 females, 18 males, mean age: 11.8±1.2). The linear and angular measurements were evaluated on lateral cephalometric radiographs at beginning (T0) and end of treatment (T1). Results: The amounts of increase in the inferior airway space, L1xNB, IMPA …


Clinical And Radiographic Features Of Nevoid Basal Cell Carcinoma Syndrome: A Case Report, G Subhas Babu, Devika S. Pillai, Shruthi Hegde, Padmaraj Hegde, Vidya Ajila 2022 Department of Oral Medicine and Radiology, A B Shetty Memorial Institute of Dental Sciences, Mangaluru, India

Clinical And Radiographic Features Of Nevoid Basal Cell Carcinoma Syndrome: A Case Report, G Subhas Babu, Devika S. Pillai, Shruthi Hegde, Padmaraj Hegde, Vidya Ajila

Journal of Dentistry Indonesia

Nevoid Basal Cell Carcinoma Syndrome, also called as Gorlin Gotz syndrome is an autosomal dominant disorder characterized by the presence of multiple odontogenic keratocysts (OKCs) of the jaw, basal cell carcinomas and skeletal anomalies. Presence of multiple OKCs is the first clinical manifestation in majority of the cases. Early diagnosis and treatment are of utmost importance in reducing the severity of this syndrome. We hereby report a rare case of Gorlin Goltz syndrome in a 28 years old female patient who presented with multiple cystic lesions in the jaws. Present case also highlights the clinical, radiographic and histopathologic features of …


Assessment Of The Effects Of Edentulousness On Temporomandibular Components By Using Cone Beam Computed Tomography, Büşra Arıkan, Numan Dedeoğlu, Şuayip Burak Duman 2022 Department of Oral and Maxillofacial Radiology, Faculty of Dentistry, Inönü University, Malatya, Turkey

Assessment Of The Effects Of Edentulousness On Temporomandibular Components By Using Cone Beam Computed Tomography, Büşra Arıkan, Numan Dedeoğlu, Şuayip Burak Duman

Journal of Dentistry Indonesia

Objective: The aim of this study is to evaluate the effects of edentulousness on the temporomandibular joint using cone beam computed tomography (CBCT). Methods: In this study, CBCT images were evaluated in a total of 48 patients (24 dentulous, 24 edentulous). Ninety-six temporomandibular joint CBCT images were examined. Eminence inclination, condyle head widths and joint space were measured and statistically compared between the edentulous and dentulous groups. Results: The articular eminence inclination value the mediolateral width of the condyle and the anteroposterior width of the condyle were found significantly higher in the dentulous group than in the edentulous group. …


Effect Of Preflaring On Accuracy Of Endodontic Length Determination By Four Electronic Apex Locators, Arash Izadi, Maliheh Bayandari, Ezatolah Kazeminejad 2022 Dental Research Center, Golestan University of Medical Sciences, Gorgan, Iran

Effect Of Preflaring On Accuracy Of Endodontic Length Determination By Four Electronic Apex Locators, Arash Izadi, Maliheh Bayandari, Ezatolah Kazeminejad

Journal of Dentistry Indonesia

Objective: Root canal anatomy significantly impacts the working length determination. This study aimed to investigate the effect of the preflaring technique on the accuracy of four electronic apex locators. Methods: Forty-five single-canal central maxillary teeth were selected. The working length was measured before and after the coronal preparation by four types of electronic apex locators in the range of ±0.5 and ±1 mm matched for the apical constriction. The actual working length was calculated under a microscope. Data were analyzed using ICC and paired t-tests in SPSS16. A p < 0.05 was considered significant. Results: The accuracies of Root ZX, DTE, Denjoy, and Coxo apex …


Comparison Of Ultrasonography And Cone Beam Computed Tomography In The Differential Diagnosis Of Periapical Lesions: A Prospective Radiopathological Study, Gozde Serindere, Ceren Aktuna Belgin, Mert Bulte, Didar Gursoy, Fariz Salimov 2022 Department of Dentomaxillofacial Radiology, Faculty of Dentistry, Hatay Mustafa Kemal University, Hatay, Turkey

Comparison Of Ultrasonography And Cone Beam Computed Tomography In The Differential Diagnosis Of Periapical Lesions: A Prospective Radiopathological Study, Gozde Serindere, Ceren Aktuna Belgin, Mert Bulte, Didar Gursoy, Fariz Salimov

Journal of Dentistry Indonesia

Objective: The aim of this study is to evaluate the correlation between ultrasonography (USG) and cone beam computed tomography (CBCT) and the accuracy between histopathological diagnosis and preliminary diagnosis in the diagnosis of periapical lesion. Methods: 20 patients with periapical lesion in the jaw, were included in the study. The presence of expansion or perforation and dimensions of the lesion were performed with CBCT. In the examination of the lesion with USG, shape, echogenicity, vascularization of the lesion and the presence of buccal expansion and perforation, were determined. Subsequently, a biopsy was taken from the lesion for histopathological examination and …


A Cell Culture Model To Study Tobacco Associated Oral Cancer Progression And Treatment Resistance, Amanda Busch 2022 University of Nebraska Medical Center

A Cell Culture Model To Study Tobacco Associated Oral Cancer Progression And Treatment Resistance, Amanda Busch

Theses & Dissertations

Head and Neck Squamous cell carcinoma is the 6th most common cancer in the world. Risk factors for HNSCC include alcohol and tobacco consumption, infection with Human Papilloma Virus, and exposure to environmental toxins. Unlike many other cancers, the incidence of HNSCC is growing, yet the treatment options and outcomes have not been significantly improved for decades. An increased understanding of the molecular mechanisms of these cancers is needed for improvement in early diagnosis, enhanced treatment effectiveness, and cancer prevention. 4-nitroquinoline 1-oxide (4NQO) is a well-tested, tobacco mimicking, carcinogen. 4NQO produces similar histological and chemical changes found in human …


Secretion Of Salivary Proteins And Their Interactions, Karla Tonelli Bicalho Crosara 2022 The University of Western Ontario

Secretion Of Salivary Proteins And Their Interactions, Karla Tonelli Bicalho Crosara

Electronic Thesis and Dissertation Repository

Saliva’s clinical application for disease diagnosis and monitoring is limited by incomplete knowledge of salivary protein interactions, the effect of stimulation on the salivary proteome, and if these factors impact protein identification. This thesis expands knowledge of the salivary interactome and effects of stimulation intensity and duration on parotid saliva’s proteome. First, previous in vitro studies identified 43 proteins in the histatin 1-protein network and demonstrated histatin 1’s increased stability in whole saliva when interacting with amylase. We hypothesized that protein-protein-interaction databases could enlarge the histatin 1-protein network. A comprehensive histatin 1-protein network was created using STRING database, merging previous …


Traumatic Ulcerative Granuloma Mimicking Squamous Cell Carcinoma In Oral Lichen Planus, David I. Tindle DDS, MS, DABOM 2022 Oral Medicine and Oral Pathology, University of Michigan School of Dentistry, Ann Arbor, Michigan

Traumatic Ulcerative Granuloma Mimicking Squamous Cell Carcinoma In Oral Lichen Planus, David I. Tindle Dds, Ms, Dabom

The Journal of the Michigan Dental Association

Background: Oral lichen planus is an immune mediated mucosal disorder affecting up to 2% of the population. Dysplasia has been known to develop in 0.1% to 1% of patients with lichen planus. This necessitates close surveillance for the development of atypical lesions.

Case: Described is the case of a 68-year-old female patient with oral lichen planus who developed a non-healing ulceration on her right lateral tongue. Out of concern for neoplasia, a biopsy was performed. Histopathologic report indicated features consistent with traumatic ulcerative granuloma. The lesion did not return.

Conclusions: Oral lichen planus is a common mucosal disease. Although uncommon, …


J Mich Dent Assoc December 2022, 2022 American Dental Association

J Mich Dent Assoc December 2022

The Journal of the Michigan Dental Association

Monthly, The Journal of the Michigan Dental Association brings news, information, and feature articles to our state's oral health community and the MDA's 6,200+ members. No publication reaches more Michigan dentists!

In this issue, the reader will find the following original content:

  • A cover story on Ensuring an Inclusive Environment for Deaf and Hard of Hearing Patients.
  • A clinical feature: Traumatic Ulcerative Granuloma Mimicking Squamous Cell Carcinoma in Lichen Planus.
  • Feature information on the University of Michigan’s BioArtography Project.
  • A recap on MDA volunteer leadership activity at the 2022 ADA House of Delegates.
  • News you need, Editorial and regular department …


Therapeutic Management Of A Case Of Chronic Myofacial Pain, Anissa Abdelkoui, Jihane Elaoud, Ahmed ABDEDINE, Nadia Merzouk 2022 Association of Arab Universities

Therapeutic Management Of A Case Of Chronic Myofacial Pain, Anissa Abdelkoui, Jihane Elaoud, Ahmed Abdedine, Nadia Merzouk

International Arab Journal of Dentistry

Myofacial pain is a common form of temporomandibular disorders. It is manifested by a sensory, motor and autonomous symptoms caused by trigger points. These pains can significantly affect patients’ quality of life, when they persist. Several etiological factors have been implicated in the genesis of the myofacial pain: muscle overload, emotional tension, harmful postural habits, fatigue, and hypovitaminosis... The diagnosis of myofacial pain is based on a pertinent history and clinical examination. Several therapeutic options alone or in combination have proven their effectiveness. This article aims, through a clinical case, to focus on myofacial pain, possible therapeutics, by focusing on …


Amelogenesis Imperfecta: Case Series And Review Of The Literature, Andrew T. Moshman DMD, Gwen Cohen-Brown DDS, FAAOMP 2022 New York City College of Technology

Amelogenesis Imperfecta: Case Series And Review Of The Literature, Andrew T. Moshman Dmd, Gwen Cohen-Brown Dds, Faaomp

The New York State Dental Journal

Amelogenesis imperfecta (AI) describes a group of genetic conditions affecting the thickness, microstructure, and degree of mineralization of the enamel. Correct diagnosis may be important for managing other serious medical conditions. AI patients are highly susceptible to caries, pain, tooth wear, and loss of the vertical dimension of occlusion, often requiring significant dental treatment throughout their life. Early diagnosis and timely preventative and restorative treatments are crucial to circumvent AI’s psychological, social, and functional sequalae. This case series highlights AI in a 19-year-old patient, with suggestions for further testing and monitoring of the condition.


N Y State Dent J November 2022, 2022 American Dental Association

N Y State Dent J November 2022

The New York State Dental Journal

In the November 2022 issue, the reader will find the following feature articles:

  • Medications Associated with Oral Lichenoid Lesions: A Single-Site Retrospective Cohort Study
  • Evaluating the Impact of Providing Free Dental Treatment to Vulnerable Populations
  • Amelogenesis Imperfecta: Case Series and Review of the Literature

This issue includes regular columns with regional news impacting the New York membership including: editorial and perspectives columns, legal, association activities, component news, continuing education opportunities, and classifieds.


Medications Associated With Oral Lichenoid Lesions: A Single-Site Retrospective Cohort Study, Debra K. Fischoff DMD, MS, Sara Sternbach DDS, Juliana Gomez DDS, Sonal S. Shah DDS 2022 New York University

Medications Associated With Oral Lichenoid Lesions: A Single-Site Retrospective Cohort Study, Debra K. Fischoff Dmd, Ms, Sara Sternbach Dds, Juliana Gomez Dds, Sonal S. Shah Dds

The New York State Dental Journal

BACKGROUND: The investigators aim to determine the frequency of systemic medications in patients with oral lichen planus or oral lichenoid lesions. METHODS: A retrospective study of lichenoid diagnoses in the New York University College of Dentistry Oral Medicine Clinic. Data obtained included patient demographics, prescription medications and pathologic diagnosis. Comparative analysis was performed. RESULTS: A total of 162 oral lichenoid lesion/oral lichen planus patients were identified: The most frequently found medications were anti-hypertensives, anti-hyperlipidemics followed by metformin, proton pump inhibitors and levothyroxine. CONCLUSION: The findings emphasize the importance of clinicians’ awareness of potential oral adverse reactions from certain medications.


10-Minute Ebd: Should Chipped Or Worn Dental Sealants Be Observed, Touched Up, Or Restored?, Elliot Abt DDS, MS, MSc 2022 University of Illinois School of Dentistry

10-Minute Ebd: Should Chipped Or Worn Dental Sealants Be Observed, Touched Up, Or Restored?, Elliot Abt Dds, Ms, Msc

The Journal of the Michigan Dental Association

This column discusses the management of chipped or worn dental sealants in a 22-year-old patient seeking a second opinion. The author explores the need for occlusal restorations, sealant repair, or no treatment for such cases. A literature search, guided by a PICO question, reveals strong evidence supporting sealant effectiveness in preventing caries. The Cochrane review found an 88% reduction in caries odds with sealants. Clinical guidelines and systematic reviews from organizations like the American Dental Association (ADA) further endorse sealant use. The column emphasizes the importance of universal sealant application and highlights challenges in their adoption, such as concerns over …


Assessing The Compliance Of Dental Clinicians Towards Regulatory Infection Control Guidelines Using A Newly Developed Survey Tool: A Pilot Cross-Sectional Study In India, Pragati Kaurani, Kavita Batra, Himangini Rathore Hooja, N. Gopi Chander, Anamitra Bhowmick, Suraj Arora, Suheel Manzoor Baba, Shafait Ullah Khateeb, Anshad M. Abdulla, Vishakha Grover, Priyanka Saluja 2022 Mahatma Gandhi Dental College and Hospital

Assessing The Compliance Of Dental Clinicians Towards Regulatory Infection Control Guidelines Using A Newly Developed Survey Tool: A Pilot Cross-Sectional Study In India, Pragati Kaurani, Kavita Batra, Himangini Rathore Hooja, N. Gopi Chander, Anamitra Bhowmick, Suraj Arora, Suheel Manzoor Baba, Shafait Ullah Khateeb, Anshad M. Abdulla, Vishakha Grover, Priyanka Saluja

School of Medicine Faculty Publications

Adherence to the dental practice regulatory guidelines instituted during the COVID- 19 pandemic is essential to minimize the transmission of SARS-CoV-2 strains. Given the lack of a valid and reliable survey tool to assess the adherence to dental practice guidelines, this study aims to develop, validate, and test a survey tool on a pilot sample of dental clinicians practicing in India. A survey tool was developed/validated through a sequential phasic approach: Phase Ideveloping survey using conceptual and literature framework; Phase II: ascertaining its validity and reliability; Phase III: pilot testing; and Phase IV: assessing construct validity by exploratory factor analysis …


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