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Evaluation Of Apoptotic Effect Of Betanin Nanoparticles Against Squamous Cell Carcinoma Cell Line Compared To Doxorubicin, Noha Hassanine noha.hassanine@fue.edu.eg, Future University in Egypt, Amany M. Taha Lecturer, Al Azhar University, Egypt, Eman A. AboHager Professor, Al Azhar University 2023 Teaching Assistant of Oral Pathology Department ,Faculty of Oral and Dental medicine ,Future University in Egypt

Evaluation Of Apoptotic Effect Of Betanin Nanoparticles Against Squamous Cell Carcinoma Cell Line Compared To Doxorubicin, Noha Hassanine Noha.Hassanine@Fue.Edu.Eg, Future University In Egypt, Amany M. Taha Lecturer, Al Azhar University, Egypt, Eman A. Abohager Professor, Al Azhar University

Future Dental Journal

Objective : to evaluate the anticancer effect of nano sized betanine particles (betanine NP) on squamous cell carcinoma cell line compared to doxorubicin (DOX) by measuring apoptosis through caspase 3. Methods: Three groups of the human tongue squamous cell carcinoma cell line (SCC 25) were created, and two of them were treated with DOX and betanine NP. The third group served as a negative control and was not given any treatment. To evaluate the concentration of caspase 3 using the ElISA technology, different quantities of betanin NP and DOX were administered to SCC25 at 48- and 72-hour intervals.Results: …


Assessment Of The Effects Of Edentulousness On Temporomandibular Components By Using Cone Beam Computed Tomography, Büşra Arıkan, Numan Dedeoğlu, Şuayip Burak Duman 2022 Department of Oral and Maxillofacial Radiology, Faculty of Dentistry, Inönü University, Malatya, Turkey

Assessment Of The Effects Of Edentulousness On Temporomandibular Components By Using Cone Beam Computed Tomography, Büşra Arıkan, Numan Dedeoğlu, Şuayip Burak Duman

Journal of Dentistry Indonesia

Objective: The aim of this study is to evaluate the effects of edentulousness on the temporomandibular joint using cone beam computed tomography (CBCT). Methods: In this study, CBCT images were evaluated in a total of 48 patients (24 dentulous, 24 edentulous). Ninety-six temporomandibular joint CBCT images were examined. Eminence inclination, condyle head widths and joint space were measured and statistically compared between the edentulous and dentulous groups. Results: The articular eminence inclination value the mediolateral width of the condyle and the anteroposterior width of the condyle were found significantly higher in the dentulous group than in the edentulous group. …


Effect Of Preflaring On Accuracy Of Endodontic Length Determination By Four Electronic Apex Locators, Arash Izadi, Maliheh Bayandari, Ezatolah Kazeminejad 2022 Dental Research Center, Golestan University of Medical Sciences, Gorgan, Iran

Effect Of Preflaring On Accuracy Of Endodontic Length Determination By Four Electronic Apex Locators, Arash Izadi, Maliheh Bayandari, Ezatolah Kazeminejad

Journal of Dentistry Indonesia

Objective: Root canal anatomy significantly impacts the working length determination. This study aimed to investigate the effect of the preflaring technique on the accuracy of four electronic apex locators. Methods: Forty-five single-canal central maxillary teeth were selected. The working length was measured before and after the coronal preparation by four types of electronic apex locators in the range of ±0.5 and ±1 mm matched for the apical constriction. The actual working length was calculated under a microscope. Data were analyzed using ICC and paired t-tests in SPSS16. A p < 0.05 was considered significant. Results: The accuracies of Root ZX, DTE, Denjoy, and Coxo apex …


Comparison Of Ultrasonography And Cone Beam Computed Tomography In The Differential Diagnosis Of Periapical Lesions: A Prospective Radiopathological Study, Gozde Serindere, Ceren Aktuna Belgin, Mert Bulte, Didar Gursoy, Fariz Salimov 2022 Department of Dentomaxillofacial Radiology, Faculty of Dentistry, Hatay Mustafa Kemal University, Hatay, Turkey

Comparison Of Ultrasonography And Cone Beam Computed Tomography In The Differential Diagnosis Of Periapical Lesions: A Prospective Radiopathological Study, Gozde Serindere, Ceren Aktuna Belgin, Mert Bulte, Didar Gursoy, Fariz Salimov

Journal of Dentistry Indonesia

Objective: The aim of this study is to evaluate the correlation between ultrasonography (USG) and cone beam computed tomography (CBCT) and the accuracy between histopathological diagnosis and preliminary diagnosis in the diagnosis of periapical lesion. Methods: 20 patients with periapical lesion in the jaw, were included in the study. The presence of expansion or perforation and dimensions of the lesion were performed with CBCT. In the examination of the lesion with USG, shape, echogenicity, vascularization of the lesion and the presence of buccal expansion and perforation, were determined. Subsequently, a biopsy was taken from the lesion for histopathological examination and …


Stereomicroscopic Evaluation Of Dentinal Microcracks After Instrumentation Of Curved Canal With Rotary Files In Two Motions, Nupur Vasava, Shreya Modi, Chintan Joshi, Sweety Thumar, Anisha Parmar, Kruti Jadawala 2022 Karnavati School of Dentistry, Gandhinagar, Gujarat, India

Stereomicroscopic Evaluation Of Dentinal Microcracks After Instrumentation Of Curved Canal With Rotary Files In Two Motions, Nupur Vasava, Shreya Modi, Chintan Joshi, Sweety Thumar, Anisha Parmar, Kruti Jadawala

Journal of Dentistry Indonesia

Objective: This study aimed to examine the effects of three distinct file systems with two motion types—rotary and reciprocation—on the development of dentinal microcracks after root canal preparation using a stereomicroscope. Methods: Sixty mandibular molars with a curvature of 30° were decoronated and divided into three groups (Vortex Blue, Mtwo, and ProTaper Next) and two subgroups (rotary and reciprocating motions). The samples were then instrumented with the files, dyed with 1% methylene blue dye, and sectioned horizontally at 3, 6, and 9 mm from the root apex. The dentinal microcracks were inspected using a stereomicroscope at 40× magnification. One-way analysis …


Evaluation Of Dentoskeletal And Pharyngeal Airway Changes After Treatment With Twin Block And Monoblock Appliance In Growing Patients, Esra Genc, Ahmet Karaman, Gülşah Püskül 2022 Department of Orthodontics, Faculty of Dentistry, Istanbul Aydın University, Istanbul, Turkey

Evaluation Of Dentoskeletal And Pharyngeal Airway Changes After Treatment With Twin Block And Monoblock Appliance In Growing Patients, Esra Genc, Ahmet Karaman, Gülşah Püskül

Journal of Dentistry Indonesia

Objective: To compare of pharyngeal airway dimensions and dentoskeletal changes after treatment with twin block (TWB) and monoblock (MB) appliance in growing patients. Methods: The sample was comprised of a total of 72 patients at the ages of 10 to 13. The TWB group consisted of 36 patients (22 females, 14 males, mean age: 11.9±1.5) and MB group consisted of 36 patients (18 females, 18 males, mean age: 11.8±1.2). The linear and angular measurements were evaluated on lateral cephalometric radiographs at beginning (T0) and end of treatment (T1). Results: The amounts of increase in the inferior airway space, L1xNB, IMPA …


Clinical And Radiographic Features Of Nevoid Basal Cell Carcinoma Syndrome: A Case Report, G Subhas Babu, Devika S. Pillai, Shruthi Hegde, Padmaraj Hegde, Vidya Ajila 2022 Department of Oral Medicine and Radiology, A B Shetty Memorial Institute of Dental Sciences, Mangaluru, India

Clinical And Radiographic Features Of Nevoid Basal Cell Carcinoma Syndrome: A Case Report, G Subhas Babu, Devika S. Pillai, Shruthi Hegde, Padmaraj Hegde, Vidya Ajila

Journal of Dentistry Indonesia

Nevoid Basal Cell Carcinoma Syndrome, also called as Gorlin Gotz syndrome is an autosomal dominant disorder characterized by the presence of multiple odontogenic keratocysts (OKCs) of the jaw, basal cell carcinomas and skeletal anomalies. Presence of multiple OKCs is the first clinical manifestation in majority of the cases. Early diagnosis and treatment are of utmost importance in reducing the severity of this syndrome. We hereby report a rare case of Gorlin Goltz syndrome in a 28 years old female patient who presented with multiple cystic lesions in the jaws. Present case also highlights the clinical, radiographic and histopathologic features of …


Therapeutic Management Of A Case Of Chronic Myofacial Pain, Anissa Abdelkoui, Jihane Elaoud, Ahmed ABDEDINE, Nadia Merzouk 2022 Association of Arab Universities

Therapeutic Management Of A Case Of Chronic Myofacial Pain, Anissa Abdelkoui, Jihane Elaoud, Ahmed Abdedine, Nadia Merzouk

International Arab Journal of Dentistry

Myofacial pain is a common form of temporomandibular disorders. It is manifested by a sensory, motor and autonomous symptoms caused by trigger points. These pains can significantly affect patients’ quality of life, when they persist. Several etiological factors have been implicated in the genesis of the myofacial pain: muscle overload, emotional tension, harmful postural habits, fatigue, and hypovitaminosis... The diagnosis of myofacial pain is based on a pertinent history and clinical examination. Several therapeutic options alone or in combination have proven their effectiveness. This article aims, through a clinical case, to focus on myofacial pain, possible therapeutics, by focusing on …


Assessing The Compliance Of Dental Clinicians Towards Regulatory Infection Control Guidelines Using A Newly Developed Survey Tool: A Pilot Cross-Sectional Study In India, Pragati Kaurani, Kavita Batra, Himangini Rathore Hooja, N. Gopi Chander, Anamitra Bhowmick, Suraj Arora, Suheel Manzoor Baba, Shafait Ullah Khateeb, Anshad M. Abdulla, Vishakha Grover, Priyanka Saluja 2022 Mahatma Gandhi Dental College and Hospital

Assessing The Compliance Of Dental Clinicians Towards Regulatory Infection Control Guidelines Using A Newly Developed Survey Tool: A Pilot Cross-Sectional Study In India, Pragati Kaurani, Kavita Batra, Himangini Rathore Hooja, N. Gopi Chander, Anamitra Bhowmick, Suraj Arora, Suheel Manzoor Baba, Shafait Ullah Khateeb, Anshad M. Abdulla, Vishakha Grover, Priyanka Saluja

School of Medicine Faculty Publications

Adherence to the dental practice regulatory guidelines instituted during the COVID- 19 pandemic is essential to minimize the transmission of SARS-CoV-2 strains. Given the lack of a valid and reliable survey tool to assess the adherence to dental practice guidelines, this study aims to develop, validate, and test a survey tool on a pilot sample of dental clinicians practicing in India. A survey tool was developed/validated through a sequential phasic approach: Phase Ideveloping survey using conceptual and literature framework; Phase II: ascertaining its validity and reliability; Phase III: pilot testing; and Phase IV: assessing construct validity by exploratory factor analysis …


Electromyographic Activity Of Masticatory Muscles In Asymptomatic Young Adults, Aneta Wieczorek, Malgorzata Pihut, Jolanta E. Loster 2022 Jagiellonian University Medical College, Faculty of Medicine, Institute of Dentistry, Department of Prosthodontics and Orthodontics, Krakow, Poland

Electromyographic Activity Of Masticatory Muscles In Asymptomatic Young Adults, Aneta Wieczorek, Malgorzata Pihut, Jolanta E. Loster

Journal of Dentistry Indonesia

Introduction: The masseter and the anterior part of the temporalis are the muscles mainly responsible for the clenching function. Clenching patterns and the activity of these muscles are not expected to differ between male and females, nor between different occlusal classes. Objective: The aim of this study was to determine whether the activity index of the masseter and temporalis muscles is related to occlusal class and gender. Methods: This study involved 145 eighteen-year-old Caucasian volunteers who underwent surface electromyography. The sEMG was analyzed at the moment of 100% occlusal contact. Occlusal classes were determined used plaster casts. …


Fractal Analysis Of Subchondral Cyst At Mandibular Condyle Detected On Panoramic Radiograph In A Group Of Thai Population, Aloysius Putut Wijanarko, Preeyaporn Srimawong, Suchaya Pornprasertsuk-Damrongsri, Apirum Janhom 2022 Department of Oral and Maxillofacial Radiology, Faculty of Dentistry, Mahidol University, Bangkok, Thailand

Fractal Analysis Of Subchondral Cyst At Mandibular Condyle Detected On Panoramic Radiograph In A Group Of Thai Population, Aloysius Putut Wijanarko, Preeyaporn Srimawong, Suchaya Pornprasertsuk-Damrongsri, Apirum Janhom

Journal of Dentistry Indonesia

Objectives: This study aimed to analyze subchondral cyst on the mandibular condyle using fractal dimension (FD) measurement on a panoramic radiograph. Methods: This retrospective study examined 15 patients aged 24 to 75 years who had undergone panoramic radiography and cone-beam computed tomography on both sides of the mandibular condyles, between January 2013 and November 2017, in the Oral and Maxillofacial Radiology Clinic, Dental Hospital, Mahidol University. These 15 patients, all of whom had a subchondral cyst on one side of the mandibular condyle, constituted both the study and control groups: the 15 affected sides constituted the study group, …


The Effect Of Disc Displacement On Temporomandibular Joint Morphology In Patients With Disc Displacement, Melike Yurttaş, Esin Bozdemir, Şehnaz Evrimler 2022 Department of Dentomaxillofacial Radiology, Faculty of Dentistry, Kutahya Health Sciences University, Kutahya, Turkey

The Effect Of Disc Displacement On Temporomandibular Joint Morphology In Patients With Disc Displacement, Melike Yurttaş, Esin Bozdemir, Şehnaz Evrimler

Journal of Dentistry Indonesia

Objective: To examine the morphological properties of temporomandibular joint structures by magnetic resonance imaging (MRI) on patients with and without disc displacement (DD). Methods: Thirty-eight patients with disc displacement and 13 patients without disc displacement were included. Age, gender, and clinical findings such as pain, joint sounds of patients were recorded. The patients were classified as anterior disc displacement with reduction (ADDWR) group, anterior disc displacement without reduction (ADDWoR) group, and control group on MRI. Disc morphology was categorized as biconcave, hemiconvex, biconvex, biplanar, or folded. Condyle morphology was characterized as convex, angled, flat, or rounded. Articular eminence …


Effects Of Lime (Citrus Aurantifolia Swingle) Peel Extract Addition To Periodontal Dressing On The Number Of Blood Vessels In The Gingival Wound Healing Process, Malianawati Fauzia, Savira Pratista Oktaviana 2022 Department of Periodontics, Faculty of Dentistry, Universitas Brawijaya, Malang, Indonesia

Effects Of Lime (Citrus Aurantifolia Swingle) Peel Extract Addition To Periodontal Dressing On The Number Of Blood Vessels In The Gingival Wound Healing Process, Malianawati Fauzia, Savira Pratista Oktaviana

Journal of Dentistry Indonesia

Background: Periodontal dressings that are currently available can only protect wounds from mechanical trauma, but have no ability to accelerate wound healing. Lime (Citrus aurantifolia Swingle) peel extract added to periodontal dressing contains flavonoids which can stimulate the formation of new blood vessels, thus accelerating the healing process. Objective: To determine the effects of adding lime (Citrus aurantifolia Swingle) peel extract to periodontal dressing on the number of blood vessels in the gingival wound healing process. Methods: 32 rabbits with 2 mm wound made on the gingiva were divided into 8 groups. For the control groups of …


Primary Oral Myiasis Of Anterior Maxilla In An Intellectually Disabled Female – A Case Report, Sridhar M, Shivayogi Charantimath, Anjana Bagewadi, Lokesh Kumar S, Arun Panwar, Jayapriya T, Vaishali Keluskar 2022 KAHER’S KLE VK Institute of Dental Science, Karnataka, India

Primary Oral Myiasis Of Anterior Maxilla In An Intellectually Disabled Female – A Case Report, Sridhar M, Shivayogi Charantimath, Anjana Bagewadi, Lokesh Kumar S, Arun Panwar, Jayapriya T, Vaishali Keluskar

Journal of Dentistry Indonesia

“Myiasis” is a term used to represent invasion caused by fly larvae that affect organs and tissues of human beings and feeds on the host tissue. It is a rare and non-specific pathology that varies according to the species of fly larvae and the area of the body involved. Various factors like extraction wounds, uncontrolled diabetes, necrotic tissues, alcohol addiction, poor oral hygiene, immunocompromised conditions and people with special care needs like debilitated or mentally challenged individuals predispose to develop myiasis. We hereby report a case of oral myiasis of the maxillary anterior region of the palate and labial mucosa, …


Extrinsic And Intrinsic Factors Influencing Homeostasis And Repair In Oral Tissues, Georgia Nikoloudaki 2022 The University of Western Ontario

Extrinsic And Intrinsic Factors Influencing Homeostasis And Repair In Oral Tissues, Georgia Nikoloudaki

Electronic Thesis and Dissertation Repository

The oral tissues, including gingiva and buccal mucosa, heal rapidly with minimal scar formation. Although in the oral cavity, the palatal mucosa is associated with excessive scarring in response to injury. In this thesis, first, I investigated the complex relationship between cells and their microenvironment using wound healing models in which extracellular matrix composition and mechanical stiffness affect cellular responses during acute wound repair. I also determined how intrinsic differences of cells recruited during healing contribute to wound resolution.

In Chapter 2, I first investigated cell-extrinsic factors, specifically the influence of the pro-fibrotic matricellular protein periostin on palatal healing. Using …


Preliminary Analysis Of Transcriptomic Variations In Esrp1/Sox2 Double Transgenic Mouse Embryo Facial Prominences In Search Of Esrp1 Targets Responsible For Cleft Lip And/Or Palate Pathogenesis, Grace Lee 2022 University of Pennsylvania

Preliminary Analysis Of Transcriptomic Variations In Esrp1/Sox2 Double Transgenic Mouse Embryo Facial Prominences In Search Of Esrp1 Targets Responsible For Cleft Lip And/Or Palate Pathogenesis, Grace Lee

Dental Theses

Cleft lip and/or palate (CL/P) is a highly prevalent craniofacial deformation worldwide, that is challenging to treat. Despite the series of reconstructive surgeries, orthodontic treatments, and functional rehabilitation therapies, patients can not fully recover from the esthetic and functional defect they were born with. A paradigm-shift in treatment approach is needed to lift the medical, psychosocial, and financial burdens from the patients and their families, one that would intercept the malformation in utero and recapitulate normal development of the lip and the palate before birth. A necessary first step towards this goal is to decipher the intricate molecular mechanisms underlying …


Dataset Of Antemortem Tooth Loss And Carious Lesions At Deir El-Medina, Anne Austin 2022 University of Missouri-St. Louis

Dataset Of Antemortem Tooth Loss And Carious Lesions At Deir El-Medina, Anne Austin

UMSL Datasets

These data are from observations on antemortem tooth loss and the presence of carious lesions from the site of Deir el-Medina, Egypt. The data were collected by Anne Austin and Mélie Louys as part of the mission of the Institut Français d’Archéologie Orientale at the site during the 2012-14 and 2019-20 field seasons. These data were derived from human remains found in Theban Tombs 6, 217, 290, and 298. They are estimated to date from 1550-945 BCE. These data include macroscopic observations from 32 mandibles and 44 maxillae consisting of 485 observable teeth and 1,052 observable tooth sockets. Any mandibles …


Dataset Of Antemortem Tooth Loss And Carious Lesions At Deir El-Medina, Anne Austin 2022 University of Missouri-St. Louis

Dataset Of Antemortem Tooth Loss And Carious Lesions At Deir El-Medina, Anne Austin

History Faculty Works

These data are from observations on antemortem tooth loss and the presence of carious lesions from the site of Deir el-Medina, Egypt. The data were collected by Anne Austin and Mélie Louys as part of the mission of the Institut Français d’Archéologie Orientale at the site during the 2012-14 and 2019-20 field seasons. These data were derived from human remains found in Theban Tombs 6, 217, 290, and 298. They are estimated to date from 1550-945 BCE. These data include macroscopic observations from 32 mandibles and 44 maxillae consisting of 485 observable teeth and 1,052 observable tooth sockets. Any mandibles …


A Rat Experimental Model For Investigation Of The Effect Of Diabetes On Submandibular Salivary Glands Treated With Epidermal Growth Factor, Mahmoud Bakr, Mohamed Shamel, Sara Abdelwahed, Mahmoud Al Ankily 2022 Griffith University - Australia

A Rat Experimental Model For Investigation Of The Effect Of Diabetes On Submandibular Salivary Glands Treated With Epidermal Growth Factor, Mahmoud Bakr, Mohamed Shamel, Sara Abdelwahed, Mahmoud Al Ankily

Dentistry

BACKGROUND: Despite the plethora of research around the negative effects of diabetes on different body organs, this topic still attracts a lot of attention to find potential remedies that could counteract or reverse the damaging effect of diabetes.AIM: In this study, we developed a reliable experimental rat model that can be used for the investigation of the ability of epidermal growth factor (EFG) in restoring the normal architecture of oral tissues after being damaged by diabetes.METHODS: Eighty adult male albino rats (average weight ±220 gm) were used in the current study. Twenty rats served as control and received no treatment. …


Aggregatibacter Actinomycetemcomitans Exploits And Modulates The Immune Response By Human Neutrophils For Survival In The Anaerobic Environment., Hazel Ozuna 2022 University of Louisville

Aggregatibacter Actinomycetemcomitans Exploits And Modulates The Immune Response By Human Neutrophils For Survival In The Anaerobic Environment., Hazel Ozuna

Electronic Theses and Dissertations

Aggregatibacter actinomycetemcomitans (Aa) is a Gram-negative facultative anaerobe and an opportunistic oral pathogen, strongly associated with localized periodontitis and other inflammatory diseases. Periodontitis is a chronic inflammation of the periodontium resulting from the inflammatory response of the host towards the dysbiotic microbial community present at the gingival crevice. The host immune response creates a hostile environment for microorganisms; therefore, it is important for Aa to be able to regulate the necessary genes to survive and thrive in such an environment. Aaexpresses several virulence factors such as a cytolethal distending toxin (Cdt), lipopolysaccharide (LPS) and leukotoxin A (LtxA), …


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