Oral Biology and Oral Pathology Commons^™

Oral Leukoplakia: Diagnosis And Management Revisited, Isaäc Van Der Waal

Journal of Dentistry Indonesia

The definition of oral leukoplakia has not much changed during the past five decades and is still a definition by exclusion of ‘known’ lesions. Therefore, a diagnosis of leukoplakia is not always a straightforward one for the clinicians and, to some extent, also for the pathologists. The traditional clinical classification in homogeneous and nonhomogeneous leukoplakia may just be simplified into leukoplakia (thin and thick/verrucous) and erythroleukoplakia. In spite of numerous reported predictive molecular and genetic parameters of malignant transformation, the presence and grade of epithelial dysplasia as assessed by histopathological examination is still the most important one. Of the various …

Salivary Changes In Patients Hospitalized For Complications Of Hiv Infection/Aids: A Study Using Inductively Coupled Plasma Optical Emission Spectrometry, Vanessa Cavassin Klamas, Mateus Anhaia Ventura, Loana Mara Baika, Adryano Arana Kamei, Jhonatan Yukio Naka, Cassiano Lima Chaiben, Marco Tadeu Grassi, Antonio Adilson Soares De Lima

Journal of Dentistry Indonesia

Objective: The aim of this study was to analyze the salivary flow and levels of major salivary ions of HIV-infected individuals. Methods: One hundred and two participants (18 - 74 years of age) were divided into two groups (51 HIV - infected patients and 51 controls) and had a saliva sample collected. Salivary flow rate was measured gravimetrically. Levels of salivary sodium, potassium, magnesium, calcium and phosphorus were analyzed by inductively coupled plasma optical emission spectrometry (ICP-OES). Results: The mean salivary flow of subjects with HIV infection was significantly higher when compared to controls (Case group = …

The Biocompatibility Of A Ginger-Containing Herbal Toothpaste On Developing Zebrafish Embryos, Simge Meseli, Unsal Veli Ustundag, Perihan Seda Ates, Ismail Unal, Ebru Isik Alturfan, Dilek Tağtekin, Funda Yanikoglu

Journal of Dentistry Indonesia

The biocompatibility of toothpaste in an oral cavity should be approved by clinical trials. Nowadays, herbal toothpaste is increasing in popularity due to its natural ingredients. Being genetically similar to humans, zebrafish are used in potential toxicity testing. The zebrafish embryotoxicity test is a fast and straightforward method to study chemical toxicity during embryogenesis.

Objective: This study aimed to evaluate if there was any biocompatibility of the toothpaste on zebrafish embryos.

Methods: Adult AB strain zebrafish were used according to Institutional Animal Care and Use Committee protocols. Normally dividing, spherical embryos were exposed to herbal toothpaste with ginger (Gumgumix, Turkey) …

Perceived Stress, Severity Of Xerostomia, And Periodontal Status In Undergraduate Dental Students, Engku Ahmad Muzhaffar, Zurairah Berahim, Norsila Abdul Wahab, Norkhafizah Saddki

Journal of Dentistry Indonesia

Dentistry is a highly stressful program; stress is associated with xerostomia and periodontal disease.

Objective: This study aims to investigate the association of perceived stress, severity of xerostomia, and periodontal status in dental students.

Methods: This was a two-phase cross-sectional study of 245 Universiti Sains Malaysia (USM) undergraduate dental students. Phase 1 involved administration of the Perceived Stress Scale (PSS-10) and Summated Xerostomia Inventory (SXI). In phase 2, the Community Periodontal Index (CPI) was performed on 150 students to determine their periodontal status.

Results: Mean PSS-10 and SXI scores were 19.6 (SD 5.47) and 7.9 (SD 2.04), respectively. …

How To Manage Fan’S C Shape Canals Along With S Shape Morphology In Indian Population: A Case Series And Narrative Review, A Lavanya, Rajendra Kumar Tewari

Journal of Dentistry Indonesia

The C-shaped root canals offer greater negotiation, debridement, and obturation difficulty as they present with intercommunications, lateral canals, and reduced dentin thickness.

Objective: This case series elaborates on the recognition that these varying configurations is important to enhance adequate cleaning, shaping, and sealing of the root canal.

Case Reports: On clinical examination, all the teeth showed caries were nonresponsive to sensibility tests and toother diagnostic tests, suggestive of pulp necrosis with apical periodontitis. Conventional root canal treatment with different techniques and obturation systems have been used. This case series presents the successful management of various C-shaped configurations classified by Fan …

Expression Of Vimentin, Α-Sma And Tgf-Β In Different Grades Of Oral Squamous Cell Carcinoma, Hala El-Kammar, Waleed F. Esmael, Nermeen S. Afifi

Future Dental Journal

Abstract

Background: Oral Squamous cell carcinoma (OSCC) is typically discovered at an early stage; nevertheless, regional lymph node metastases are prevalent; therefore, surgical excision of the primary tumor is commonly coupled with neck dissection and radiotherapy. Cancer cells become invasive by acquiring a mesenchymal phenotype, a process known as the epithelial-to-mesenchymal transition. Vimentin, α-SMA and TGF-β expressions are believed to take part in EMT and tumor progression. Aim: this work aimed to evaluate the expression of Vimentin, α-SMA and TGF-β on OSCC progression and hence propose potential role as potential prognostic markers or therapeutic targets. Materials and methods: twenty-four specimens …

Computer Guided Versus Conventional Maxillary Sinus Augmentation Using Allogenic Bone Blocks With Simultaneous Implant Placement In Severely Pneumatized Sinuses, Hisham G. Zulhemma Department Of Oral And Maxillofacial Surgery, Future University In Egypt, Egypt. 20172740@Fue.Edu.Eg, Waleed Ragab El-Beialy Professor Of Oral And Maxillofacial Surgery -Cairo University, Egypt. Wbeialy@Yahoo.Com, Ahmed Abd Elsamad Associate Professor Of Oral And Maxillofacial Radiology– Cairo University, Egypt. Abdalsamad_A@Yahoo.Com, Ahmed Abozekry Lecturer Of Oral And Maxillofacial Surgery –Future University In Egypt, Egypt. Ahmed.Kamal@Fue.Edu.Eg

Future Dental Journal

Background: Maxillary sinus lifting is a complex procedure with reported complications in the literature where the presence of sinus septa further complicates the procedure, they including membrane perforation, bleeding. Aim: The aim of this study is to decrease the incidence of membrane perforation which is the most common reported complication, and to determine whether the use of surgical guides could decrease the incidence of membrane perforation. Materials and methods: A total of 12 cases where blindly divided into 2 groups; Group (A) computer guided maxillary sinus lifting and Group (B) conventional sinus lifting, both groups received allogenic bone blocks for …

Therapeutic Effect Of Curcumin, Ginger And Tamarind On Oral And Paraoral Tissues: (Histological Overview), Mona El Deeb, Amany A. Rabea

Future Dental Journal

Background: Biocompatible substances from plant origin have been more in focus in contemporary dentistry. Aim: This review, aimed to highpoint the influence of curcumin, ginger and tamarind on different oral and paraoral tissues from histological point of view. Material and methods: A narrative review was carried out based on publications in PubMed, google and Scopus database. The documents published up to 2021 were included. The research was based on inclusion criteria of 89 studies.Results: Curcumin inhibits alveolar bone resorption, reduces inflammatory cell infiltration, aids in epithelial regeneration and improves salivary glands architecture. Ginger was found to be beneficial in …

Epidemiological Distribution Of Primary Salivary Gland Tumors. Retrospective Analysis In Baghdad Medical City, Osama Mohammed Ghazi

Maaen Journal for Medical Sciences

Background: Studies on the incidence of salivary tumors around the world showed variations, including in Iraq. This study was intended to evaluate the relative incidence of these tumors among the Iraqi population. Materials and methods: The current retrospective study encompassed 109 cases retrieved from the file records of the pathology laboratory of Baghdad Medical City over a five-year period from January 2017 to December 2021. Information regarding age, gender, site, and tumor type was assembled and analyzed using a statistical package for social sciences (SPSS version 20). Results: The present study documented that salivary gland tumors represent 1.35% of the …

The Emerging Oral Pathogen, Filifactor Alocis, Modulates Antimicrobial Responses In Primed Human Neutrophils., Ian J. Snider

College of Arts & Sciences Senior Honors Theses

Periodontitis is an irreversible, chronic inflammatory, infectious disease of the oral cavity that affects approximately half of all adults 30 years or older in the USA. The oral cavity is under high immune surveillance because of its constant exposure to microbes in the environment. The primary immune cell responsible for this surveillance is the neutrophil. Pathogens associated with periodontitis possess virulence factors and have evolved strategies to evade neutrophil antimicrobial responses to survive. One such pathogen is Filifactor alocis, whose presence is associated with the progression of periodontitis. F. alocis manipulates several neutrophil antimicrobial functional responses to avoid killing, an …

Education, Beliefs, And Health Literacy Of Care Providers On Mouth Care Of Older Adults, Molly Lakin

Honors Theses, University of Nebraska-Lincoln

Oral health is important to one’s overall health and quality of life as it can lead to chronic illnesses such as cardiovascular disease, stroke, and neurodegenerative disorders (Haumschild et al. 2021). In long-term care facilities, it is important that dependent older adults are provided mouth care to maintain their oral health and decrease their chances of developing a chronic illness; however, there are barriers affecting the level, quality, and quantity of mouth care being provided in these facilities. A survey was developed to look at the education, beliefs, and health literacy of care providers on providing mouth care in hopes …

A Clinical Reference Guide To The Treatment Of Common Oral Lesions, Janet Zalucha Dds, Felipe Nör Dds, Ms, Phd, David Tindle Dds, Ms

The Journal of the Michigan Dental Association

This special MDA Journal pull-out is created as a quick reference for practitioners to assist their patients who present with some of the most common oral pathology manifestations. When encountering these conditions, please consider coordinating care and collaborating with practitioners who have had additional, specialized training in the respective fields. Treatment recommendations for each condition described are included. Note that many of these are considered off-label use of the listed agents. Full prescribing information is beyond the scope of this quick reference guide, so practitioners should thoroughly familiarize themselves with each agent chosen for use.

Compound Odontoma:Diagnosis And Treatment: Case Report, Georgina El Ghoule, Bassam Salameh, Wassim Al Manhal

International Arab Journal of Dentistry

Odontomas are an asymptomatic benign odontogenic tumors, generally discovered fortuitously, or when a tooth failed to erupt. They are mainly composed of enamel and dentin, cement and pulp tissue can also be present in variable amounts. In 2005, the World Health Organization classified two main types of odontoma, an amorphous and irregular mass of calcified dental tissues as complexe odontoma and multiple miniature tooth-like structures as compound odontoma. This article is a case presentation of a compound odontoma diagnosed for an eleven year old girl upon a routine radiography, making it a lesion of childhood /adolescence. A retro-alveolar radiography of …

Oral Manifestations Of Acute Lymphocytic Leukemia, Angela Yepes Dds, Ms, Mba, Juan Yepes Dds, Md, Mph, Ms, Drph, James E. Jones Dmd, Msd, Edd, Phd

The Journal of the Michigan Dental Association

Leukemia is the most prevalent malignancy of leukocytes and can occur in children and adults. Oral manifestations are part of the complexity of signs and symptoms in patients with leukemia and, in some patients, oral manifestations precede systemic manifestations. Oral signs of leukemia include spontaneous bleeding, gingival enlargement, and whiteness of the oral mucosa. Head and neck lymphadenopathy is common in patients with leukemia. Oral manifestations are the result of the direct invasion of immature cells in the oral cavity tissues or indirectly caused by the replacement of the normal blood cells for immature cells causing anemia, leucopenia, and thrombocytopenia. …

Do Nasal Anatomical Variations Affect The Maxillary Sinus? A Cbct Volumetric Analysis, Raghdaa A. Mostafa, Sahar M. Samir

Journal of Dentistry Indonesia

Objective: This study aimed to determine the effect of the concha bullosa (CB) and the nasal septum deviation (NSD) on the volume of the maxillary sinuses using ITK-SNAP (http://www.itksnap.org/ download/snap/). Methods: A total of 70 CBCT scans were analyzed. Three groups were evaluated; control (absence of CB), unilateral CB, and bilateral CB. Moreover, scans were classified according to the NSD into control (no deviation), mild, moderate, and severe NSD deviation. The volume of each maxillary sinus was calculated using the ITKSNAP. Intra-observer reliability analysis was performed by paired-sample t-test. Analysis of variance ANOVA and t-test were used to …

A Two-Year Retrospective Evaluation Of Cone Beam Computed Tomography Indications In Pediatric, Adolescent And Adult Patients, Zeynep Betül Arslan, Esra Ceren Tuğutlu

Journal of Dentistry Indonesia

Objective: The objective was to evaluate cone-beam computed tomography (CBCT) indications and distribution in pediatric, adolescent and adult patients. Methods: A total of 1013 CBCT images were reviewed in detail from the electronic patient database. The patient’s age, gender, CBCT indications and acquisition sites, referral departments, reason for referral, incidental findings in the imaging field and the presence of artifacts in the CBCT images were all recorded. The European DIMITRA project recommendations were used to categorize CBCT indications in the children and the European Guidelines were used for adults. Results: From a total of 1013 images; 5.3% …

Head And Neck Tumor Histopathological Image Representation With Pre- Trained Convolutional Neural Network And Vision Transformer, Ranny Rahaningrum Herdiantoputri, Daisuke Komura, Tohru Ikeda, Shumpei Ishikawa

Journal of Dentistry Indonesia

Image representation via machine learning is an approach to quantitatively represent histopathological images of head and neck tumors for future applications of artificial intelligence-assisted pathological diagnosis systems. Objective: This study compares image representations produced by a pre-trained convolutional neural network (VGG16) to those produced by a vision transformer (ViT-L/14) in terms of the classification performance of head and neck tumors. Methods: W hole-slide images of five oral t umor categories (n = 319 cases) were analyzed. Image patches were created from manually annotated regions at 4096, 2048, and 1024 pixels and rescaled to 256 pixels. Image representations were …

Treatment Of Oral Vascular Malformations With Ethamolin: A Report Of Two Cases, Maria Clara De Moura Santos Coelho Ferreira, Marco Vinícius De Sales Lima, Anna Laura Almeida Barreto, Dárcio Kitakawa, Alexandre Do Prado Scherma, Felipe Peralta, Luis Felipe Das Chagas E Silva De Carvalho

Journal of Dentistry Indonesia

A hemangioma is a benign vascular neoplasm, relatively common in the head and neck. In the oral region, it affects the tongue, gums, mucosa, palate, and lip. Its size can vary from millimeters to centimeters, characterized as a purplish or reddish lesion. The present study aims to present two clinical cases of hemangiomas, the first of a male patient treated by sclerotherapy and the second of a female patient in which she was treated with ethamolin and later surgical treatment. It was concluded that sclerotherapy, in addition to being a safe treatment, managed to drastically reduce the initial size of …

A Prospective-Randomized Study: The Impact Of Four Different Caries Removal Method On Pain And Clinical Evaluations, Merve Aydemir, Serdar Bağlar

Journal of Dentistry Indonesia

Objective: There are many different methods for removing caries. In this study, to evaluate four caries removal methods in terms of patient comfort and to evaluate the clinical success of restorations according to modified-USPHS criteria. Methods: In 31 patients with at least 4 Class II caries in their posterior teeth, 4 teeth were randomly divided into four groups and 4 different methods (conventional method, Carisolv, Papacarie, Er-Cr:YSGG Laser) were used for caries removal. Pain formation during caries removal was determined by FACE Pain Scale questionnaire. The restorations were controlled with Modified-USPHS criteria in 3-6-12 months period. Mann-Whitney U …

Treatment Of Gingival Fenestration Using Mucoperiosteal Flap With Connective Tissue Graft: A Report Of Two Cases, Swati Jaglan, Shikha Tewari

Journal of Dentistry Indonesia

Fenestration term is derived from the Latin word ‘fenestra’ means ‘window’. Gingival fenestration is not found in routine while its actual occurrence is assumed to be higher. Additionally, if these mucogingival defects persist for a longer duration it may lead to adverse outcomes like compromised esthetics, hypersensitivity, plaque and calculus deposition, and susceptibility to dental caries. Present cases of gingival fenestration were successfully treated by using full-thickness flap elevation with connective tissue graft placement. Two cases were presented with the accumulation of plaque and calculus and having gingival fenestration to the respective sites. After phase 1 therapy, full thickness flap …