Direct Composite Resin Restoration Of Anterior Maxillary Teeth And Esthetic Smile Design: A Case Report,
2020
Department of Conservative Dentistry, Universitas Gadjah Mada, Yogyakarta 55281, Indonesia
Direct Composite Resin Restoration Of Anterior Maxillary Teeth And Esthetic Smile Design: A Case Report, Christina Widya Nugrohowati, Wignyo Hadriyanto, Tunjung Nugraheni
Journal of Dentistry Indonesia
Dental esthetic complex involves more than one caries with malformed shape and malposition. Dental trauma most commonly affects maxillary anterior teeth, and subsequently affects the esthetics, functions, and psychological well-being of the individual. Composite resins have become an integral part of contemporary restorative and minimally invasive dentistry. Objective: To summarize the successful use of direct composite resin restoration in the management of a 29-year old male patient. Case Report: A 29-year old male patient presenting with multiple secondary caries and crown fractures in the anterior maxillary teeth, resulting in an unaesthetic smile. Comprehensive esthetic dental treatment was carried out. The …
Effectiveness Of Lentinus Edodes Mushroom Extract On Eradication Of Enterococcus Faecalis Biofilm,
2020
Postgraduate Program, Faculty of Dentistry, Trisakti University, Jakarta 11440, Indonesia
Effectiveness Of Lentinus Edodes Mushroom Extract On Eradication Of Enterococcus Faecalis Biofilm, Putri Lestari Anggiarini, Meiny F Amin, Juanita A Gunawan, Armelia Sari Widyarman
Journal of Dentistry Indonesia
Sodium hypochlorite is a commonly used irrigation solution in endodontic procedures, but it irritates tissues and has toxic effects. Lentinus edodes is a mushroom that has antibacterial properties. Enterococcus faecalis is an anaerobic bacterium that can cause root canal treatment failure. Objective: This study aimed to determine the effect of L. edodes extract on the eradication of E. faecalis biofilms. Methods: Phytochemical tests of L. edodes were performed to analyze alkaloids, steroids, triterpenoids, phenolics, tannins, flavonoids, and glycosides from this extract qualitatively. E. faecalis ATCC 29212 was cultured in brain heart infusion broth for 24 h at 37°C …
Epithelial Responses To Porphyromonas Gingivalis In The Community Context.,
2020
University of Louisville
Epithelial Responses To Porphyromonas Gingivalis In The Community Context., Zackary Ray Fitzsimonds
Electronic Theses and Dissertations
Porphyromonas gingivalis, a keystone pathogen for periodontal disease, initiates a complex molecular dialogue with gingival epithelial cells, leading ultimately to disruption of host signaling pathways. Dysbiotic host responses are also thought to contribute to the initiation and progression of oral squamous cell carcinomas. Recently, the homeostatic commensal Streptococcus gordonii has been shown to antagonize P. gingivalis-induced epithelial cell signaling events in host cells, such as proliferation and migration. The aim of this study was to characterize pathways that P. gingivalis targets to disturb host signaling, with a specific focus on pathways that S. gordonii can restore to homeostatic …
The Emerging Oral Pathogen, Filifactor Alocis, Disrupts Neutrophil Functions To Enhance Survival And Dysregulate Inflammation.,
2020
University of Louisville
The Emerging Oral Pathogen, Filifactor Alocis, Disrupts Neutrophil Functions To Enhance Survival And Dysregulate Inflammation., Irina Miralda Molina
Electronic Theses and Dissertations
Periodontitis is an irreversible, chronic inflammatory disease where pathogenic microbial communities accumulate in the gingival crevice. Advances in culture-independent techniques have facilitated the identification of new bacterial species in periodontal lesions, such as the Gram-positive anaerobe, Filifactor alocis. Neutrophils are a major component of the innate host response, and the outcome of their interaction with F. alocis may be a determinant of oral health status. While neutrophil functions typically protect the host against periodontal disease, oral pathogens have adapted to evade or disarm neutrophil microbicidal functions while promoting mechanisms that drive inflammation, which also provides a source of nutrients …
Functionalizing Nanoparticles With Cafa Protein To Target Bar Peptide For Oral Delivery Applications.,
2020
University of Louisville
Functionalizing Nanoparticles With Cafa Protein To Target Bar Peptide For Oral Delivery Applications., Hetal Desai
Electronic Theses and Dissertations
Background: Porphyromonas gingivalis adherence to Streptococcus gordonii may be important for P. gingivalis colonization in the oral cavity. Nanoparticles encapsulating synthetic peptide BAR (BAR-NPs) inhibit P. gingivalis adherence more potently than free BAR. However, BAR-NPs would exhibit low retention in an open flow environment. Hypothesis: Targeting BAR-NPs to the streptococcal surface using CafA protein will enhance their efficacy. Methods: CafA-modified NPs encapsulating BAR were synthesized using double emulsion approach. Surface binding and retention, and release kinetics of BAR from CafA-modified NPs was assessed. Functional inhibition assays were performed using dual a species biofilm. Results: CafA-modified NPs demonstrated specificity of adhesion, …
Health-Related Anxiety In The Management Of Oral Soreness In An Hivseropositive Patient,
2020
Oral Medicine Residency Program, Faculty of Dentistry, Universitas Indonesia, Jakarta, Indonesia
Health-Related Anxiety In The Management Of Oral Soreness In An Hivseropositive Patient, Masita Mandasari, Zulvia Oktanida Syarif, Febrina Rahmayanti
Journal of Dentistry Indonesia
The number of people living with HIV (PLHIV) has been increasing since the first known case in the early 1980s. However, PLHIV can also experience comorbidities, such as health anxiety. In the oral cavity, anxiety is often associated with the etiology of parafunctional habits. Anxiety can be measured using self-administered instruments, such as the Hospital Anxiety and Depression Scale (HADS) and Short-Health Anxiety Inventory (SHAI), which is specifically used in the medical setting. Objectives: We are describing a case of HIV positive patient with health anxiety who presented to the oral medicine clinic in our hospital with a complaint of …
Differential Diagnosis And Histopathological Analysis Of Localized Gingival Overgrowths: Study Of 218 Cases From Northeast Thailand,
2020
Department of Clinical Dental Health Sciences, College of Dentistry, University of the Philippines, Manila
Differential Diagnosis And Histopathological Analysis Of Localized Gingival Overgrowths: Study Of 218 Cases From Northeast Thailand, Lordjie Marr Morilla, Ajiravudh Subarnbhesaj, Poramaporn Klanrit
Journal of Dentistry Indonesia
Localized gingival overgrowths (LGOs) are relatively common clinical findings. These lesions can be associated with chronic irritation, infections, or they can represent benign or malignant tumors that can either be primary or metastatic. The etiology of these lesions is multifactorial, but the most prevalent cause is reactive hyperplasia and inflammation induced by dental plaque. Objective: This study presents the prevalence of LGOs in Northeast Thailand and identifies the most common LGOs in the region. Methods: A series of 218 LGO cases was studied. Results: Pyogenic granuloma (PG), gingival squamous cell carcinoma (GSCC), and peripheral ossifying fibroma (POF) were the three …
Evaluation Of Clinical Single Dental Implants Made Between 2013 And 2017,
2020
Ministry of Health, Diyarbakır Oral and Dental Health Hospital, Diyarbakır, Turkey
Evaluation Of Clinical Single Dental Implants Made Between 2013 And 2017, Zozan Erdoğmuş
Journal of Dentistry Indonesia
Objective: This retrospective study aimed to determine the profile of patients who underwent single tooth implants between 2013 and 1017 and to evaluate long-term follow-up and success. Methods: The results of 79 patients who underwent single dental intra-bone dental implantation in Diyarbakır Oral and Dental Health Hospital between 2013 and 2017 were evaluated separately in terms of gender, age, implanted area and number, systemic diseases affecting implant health, and missing implants. Results: In this study, single tooth implants were evaluated in 79 patients with a mean age of 39.55 years in men and 30.44 years in women. …
Erupted Compound Odontoma Associated With Missing Tooth: A Rare Case Report,
2020
Department of Oral Diagnosis, Faculty of Dentistry, Naresiun University, Phitnasulok 65000, Thailand
Erupted Compound Odontoma Associated With Missing Tooth: A Rare Case Report, Weeraya Tantanapornkul, Ruchadaporn Kaomongkolgit, Sirilawan Tohnak, Lalitkorn Promma, Soranan Chantarangsu
Journal of Dentistry Indonesia
Odontomas are one of the most frequently found odontogenic tumors that consist of dental tissues. Odontomas have been classified into two types: compound and complex odontomas. They are usually discovered on routine radiographic examination. In rare cases, the odontoma erupt into the oral cavity, called an erupted odontoma. The first case was published in 1980, and since then, there have been not more than 50 cases being reported in the literature. Most of the reported cases are erupted complex odontoma. This case report represents a rare case of an erupted compound odontoma in a young patient who came with the …
The Effect Of Egf On The Ultrastructure Of Submandibular Salivary Glands Of Albino Rats Receiving Doxorubicin,
2020
The British University in Egypt
The Effect Of Egf On The Ultrastructure Of Submandibular Salivary Glands Of Albino Rats Receiving Doxorubicin, Mohamed Shamel, Mohamed Mansy, Rabab Mubarak
Dentistry
Objectives: The present study was designed to detect the outcome of EGF injection on the cytotoxic effect of DXR induced in submandibular SG of rats regarding its ultrastructure. Methods: 30 male Albino rats, two months old and 200gm body weight were divided into three groups. Group I assisted as a control group. Group II (DXRgp), 20 mg/kg body weight DXR was injected intraperitoneally into the rats. Whereas group III (DXR+ EGF) the rats received the same dose of DXR and on the next day, they were injected intraperitoneally with EGF in a daily dose of 10µg/kg bodyweight for 7 consecutive …
Synthesis And Characterization Of Hemocompatible Antibiotic Nanoparticles,
2020
Loma Linda University
Synthesis And Characterization Of Hemocompatible Antibiotic Nanoparticles, Elvin Muhindo Walemba
Loma Linda University Electronic Theses, Dissertations & Projects
Porphyromonas gingivalis is a causative agent of periodontal disease and a risk factor for cardiovascular disease. Novel treatment of periodontal disease using nanomaterials can supplement or replace the use of antibiotics and mechanical debridement. Nanomaterials can be optimized for effectiveness and specificity and minimum toxicity. Synthesized Ag nanoparticles stabilized in Pluronic F127 were used to produce bimetallic core/shell Ag/Au nanoparticles with optimized Ag+ release and reduced toxicity. We tested the F127-stabilized nanoparticles for their antimicrobial activity and hemocompatibility in planktonic bacteria and citrated whole blood, respectively. Both Ag and Ag/Au bimetallic nanoparticles inhibited P. gingivalis W83 growth. We then evaluated …
Relationship Between Oral Health And Clinical Osteoporosis Among Hospitalized Patients With And Without Diabetes,
2020
University of Nevada, Las Vegas
Relationship Between Oral Health And Clinical Osteoporosis Among Hospitalized Patients With And Without Diabetes, Kenneth Izoura, Gayle Allenback, Amber Champion, Civon Gewelber, Michael Neubauer
School of Medicine Faculty Research
Objective: Diabetes mellitus (DM) is associated with poor oral health and osteoporosis (OP). The aim of this study was to assess the relationship between OP, periodontal disease (PD), and other dental and health outcomes in a cohort of hospitalized patients with and without DM. Method: Using a cross-sectional study design, we enrolled consecutive hospitalized patients. We administered a questionnaire to gather demographic information, oral health history, smoking history, and history of OP. We inspected their dentition and reviewed their charts. Data were analyzed using t-tests, chi-square tests, and logistic regression models. Result: Out of 301 patients enrolled, 275 had PD, …
The Effects Of Vaping On Oral Streptococci And Oral Inflammation,
2020
University of Central Florida
The Effects Of Vaping On Oral Streptococci And Oral Inflammation, Matthew Caldwell
Honors Undergraduate Theses
E-cigarette (e-cig) use is rising, but much is unknown about the effects of its vapor. This vapor contains chemicals such as propylene glycol, a known antimicrobial, and nicotine, whose derivatives are carcinogenic. Here, we study the effects of vaping on resident bacteria of the oral cavity and on oral cell inflammation. Oral streptococci are major residents in the oral cavity, with S. mutans the primary cause of dental caries. Growth and biofilm formation have been shown to be enhanced upon exposure to traditional cigarette smoke in vitro. In this study, we analyzed the effects of e-cig vapor on growth …
The Role Of Manganese In Streptococcus Sanguinis,
2020
Virginia Commonwealth University
The Role Of Manganese In Streptococcus Sanguinis, Tanya M. Puccio
Theses and Dissertations
Streptococcus sanguinis is primarily associated with oral health as a commensal bacterium. As an opportunistic pathogen, S. sanguinis is capable of colonizing heart valve vegetations, leading to the disease infective endocarditis. Previous studies from our lab have identified the high-affinity manganese transporter SsaACB as important for endocarditis virulence. The impact that manganese depletion has on S. sanguinis had never been evaluated and a secondary manganese transporter has not been identified. Thus, we employed the use of a fermentor to control large-scale growth over time and depleted manganese in an ΔssaACB mutant using a metal chelator, EDTA. The changes in …
Raman Microspectroscopic Study For The Detection Of Oral Field Cancerisation Using Brush Biopsy Samples,
2020
Technological University Dublin
Raman Microspectroscopic Study For The Detection Of Oral Field Cancerisation Using Brush Biopsy Samples, Isha Behl, Genecy Calado, Anika Vishwakarma, Stephen Flint, Sheila Galvin, Claire Healy, Marina Leite Pimentel, Alison Malkin, Hugh Byrne, Fiona Lyng
Articles
Field cancerisation (FC) is potentially an underlying cause of poor treatment outcomes of oral squamous cell carcinoma (OSCC). To explore the phenomenon using Raman microspectroscopy, brush biopsies from the buccal mucosa, tongue, gingiva and alveolus of healthy donors (n = 40) and from potentially malignant lesions (PML) of Dysplasia Clinic patients (n = 40) were examined. Contralateral normal samples (n = 38) were also collected from the patients. Raman spectra were acquired from the nucleus and cytoplasm of each cell, and subjected to partial least squares-discriminant analysis (PLS-DA). High discriminatory accuracy for donor and PML samples was achieved for both …
Effect Of Different Scaling Methods And Materials On The Enamel Surface Topography: An In Vitro Sem Study,
2020
The British University in Egypt
Effect Of Different Scaling Methods And Materials On The Enamel Surface Topography: An In Vitro Sem Study, Mahmoud Al Ankily, Fatma Makkeyah, Mohamed Shamel, Mahmoud Bakr
Dentistry
Aims and Objectives: Scaling is important for maintenance of gingival and periodontal conditions. These procedures have a harmful effect on the dental hard tissues. The aim of this study was to investigate the effects of hand and ultrasonic instruments made of stainless and titanium on the surface properties of enamel. Materials and Methods: Forty extracted premolars were used in this in vitro study and were randomly divided into four groups (n = 10). Group I received ultrasonic scaling with stainless steel tip, group II received ultrasonic scaling with titanium tip, group III hand scaling with stainless steel tip, and group …
Effects Of Aflatoxin B1 On The Submandibular Salivary Gland Of Albino Rats And Possible Therapeutic Potential Of Rosmarinus Officinalis: A Light And Electron Microscopic Study,
2020
The British University in Egypt
Effects Of Aflatoxin B1 On The Submandibular Salivary Gland Of Albino Rats And Possible Therapeutic Potential Of Rosmarinus Officinalis: A Light And Electron Microscopic Study, Mohamed Shamel, Bassant Ashraf
Dentistry
Background: Aflatoxin B1 (AFB1), a highly toxic mycotoxin, is one of the contaminants of food items such as corn, rice, nuts, and flour. This study aimed to evaluate the effect of AFB1 on the histology and ultrastructure of the submandibular salivary glands (SMSG) of albino rats and examine the possible therapeutic effect of Rosmarinus officinalis extract. Methods: This study used 21 adult male albino rats equally divided into three groups as follows: Group C (saline-treated control group); Group A (AFB1 treated group) subjected to intraperitoneal injection of AFB1 (2 mg/kg) once daily for four weeks; Group R …
Effect Of Different Scaling Methods And Materials On The Enamel Surface Topography: An In Vitro Sem Study,
2020
The British University in Egypt
Effect Of Different Scaling Methods And Materials On The Enamel Surface Topography: An In Vitro Sem Study, Mohamed Shamel, Mahmoud Bakr, Mahmoud Ankily, Fatma Makkeyah
Dentistry
Aims and Objectives: Scaling is important for maintenance of gingival and periodontal conditions. These procedures have a harmful effect on the dental hard tissues. The aim of this study was to investigate the effects of hand and ultrasonic instruments made of stainless and titanium on the surface properties of enamel. Materials and Methods: Forty extracted premolars were used in this in vitro study and were randomly divided into four groups (n= 10). Group I received ultrasonic scaling with stainless steel tip, group II received ultrasonic scaling with titanium tip, group III hand scaling with stainless steel tip, and group IV …
The Effect Of Smoking On Clinical Presentation And Expression Of Tlr-2 And Cd34 In Oral Lichen Planus Patients: Clinical And Immunohistochemical Study,
2020
The British University in Egypt
The Effect Of Smoking On Clinical Presentation And Expression Of Tlr-2 And Cd34 In Oral Lichen Planus Patients: Clinical And Immunohistochemical Study, Enji Ahmed Mahmoud, Nermin Yousif, Nermin Raouf
Dentistry
Background: Oral lichen planus is a chronic inflammatory disease which is considered as a potential precancerous condition. Numerous studies have confirmed that inflammation is a strong risk factor for cancer development. Smoking is associated with potentially malignant disorders of the oral and oropharyngeal mucosa. The adverse consequences of smoking in various pathologies are mediated by its effects on the immune-inflammatory system. Little is known about the influence of cigarette smoke content on the course of OLP and inflammatory response. Methods: Twenty oral lichen planus smoker patients, 20 oral lichen planus non-smoker patients and 20 control patients were included in this …
Single Nucleotide Polymorphism Of Prostaglandin-Endoperoxide Synthase (Ptgs2) And Defensin Beta 1 (Defb1) Genes In Malay Chronic Periodontitis Subjects,
2020
Universiti Malaya
Single Nucleotide Polymorphism Of Prostaglandin-Endoperoxide Synthase (Ptgs2) And Defensin Beta 1 (Defb1) Genes In Malay Chronic Periodontitis Subjects, Jagender Singh Jasmin Kaur
Student Works (2020-2029)
The association of prostaglandin-endoperoxide synthase 2 (PTGS2) and defensin beta 1 (DEFB1) single nucleotide polymorphisms (SNP) with chronic periodontitis (CP) have been widely studied amongst different ethnic groups such as the Chinese and European population. Thus far, no study has been done on the Malay ethnic group. Hence, this study assessed the allele and genotype frequencies of PTGS2 and DEFB1 variants in subjects with CP and periodontally healthy individuals in Malaysian Malays. Samples of 78 Malay CP subjects and 62 periodontally healthy controls were obtained from Malaysian Periodontal Database and Biobanking system (MPDBS) for this study. DNA samples were genotyped …
