Mcnamara 2011 Feature Extraction (Image Analysis), 2012 M.D. Anderson Cancer Center
Mcnamara 2011 Feature Extraction (Image Analysis), George Mcnamara
George McNamara
Feature Extraction presentation and movies in a ZIP file from a presentation I gave at ISAC 2011 in Baltomore, Md.
Feature extraction is one phrase for image analysis.
Rogers Pmn Movie - Background Information, 2012 M.D. Anderson Cancer Center
Rogers Pmn Movie - Background Information, George Mcnamara
George McNamara
Please see
http://mdc.custhelp.com/app/answers/detail/a_id/18689/~/metamatters-newsletters
for my series of MetaMorph MetaMatters articles in volume 2, numbers 3 through 6, on the Rogers PMN Panorama data set.
http://mdc.custhelp.com/app/answers/detail/a_id/18689/~/metamatters-newsletters
Brief summary (for more, see the Word doc)
The Expression Of Ecotropic Virus Integration Site-1 In Seven Cancer Cell Lines, 2012 Illinois Mathematics and Science Academy
The Expression Of Ecotropic Virus Integration Site-1 In Seven Cancer Cell Lines, Wendy Bindeman '12
Student Publications & Research
The ecotropic virus integration site-1 (EVI1) gene is a transcriptional repressor implicated in the control of cell proliferation and frequently over-expressed in cancerous cells. I investigated the expression of this gene across seven cancer cell lines of varying morphologies. The tested lines included leukemia lines Kasumi-3, U937, MOLT-4, and CEM, breast cancer line MCF7, colorectal cancer line HT-29, and glioblastoma line M059K. Kasumi-3 and HT-29 are documented to have high EVI1 expression. Protein concentrations were normalized with respect to actin using SDS-PAGE and Western blotting. Western blots for EVI1 showed expression of an unidentified protein with a molecular weight of …
Acute Myeloid Leukaemia In Children: Experience At A Tertiary Care Facility Of Pakistan, 2012 Aga Khan University
Acute Myeloid Leukaemia In Children: Experience At A Tertiary Care Facility Of Pakistan, Zehra Fadoo, Naureen Mushtaq, Saima Alvi, Muhammad Ali
Department of Paediatrics and Child Health
Objective: To document the demographics and outcome of children with Acute Myeloid Leukemia (AML) treated at a tertiary care facility of Pakistan.
Methods: A retrospective study was conducted at Aga Khan University on children (less than 15 years) diagnosed to have AML between January 2000 to May 2007.Total 40 cases were diagnosed out of which 37 charts were available for review.
Results: The average age of presentation was 8.5±4.5 years and 75% were males. The most common presenting feature was fever in 83% followed by bleeding in 41% and pallor in 39%. Initial WBC of > 100,000 was seen in 19% …
Molecular Mechanism Of Xy Gonadal Dysgenesis, 2012 Touro College
Molecular Mechanism Of Xy Gonadal Dysgenesis, Griendy Indig-Weingarten
The Science Journal of the Lander College of Arts and Sciences
One of the fundamentals of human sociology is the characterization of the people around us based on gender. We tend to think of gender as a strict binary system where the option is clear: boy or girl. Although society usually honors this dichotomy, biology allows more flexibility to the definition of male versus female. Estimates state that one in every 2000 births is one with a disorder of sex development (The Intersex Society of North America 2006). Some of the disorders are visually obvious while others are only discovered later on in life. Regardless of when the disease first becomes …
Shared Resistance To Aging And Als In Neuromuscular Junctions Of Specific Muscles, 2012 Harvard University
Shared Resistance To Aging And Als In Neuromuscular Junctions Of Specific Muscles, Gregorio Valdez, Juan C. Tapia, Jeff W. Lichtman, Michael A. Fox, Joshua R. Sanes
Anatomy and Neurobiology Publications
Normal aging and neurodegenerative diseases both lead to structural and functional alterations in synapses. Comparison of synapses that are generally similar but respond differently to insults could provide the basis for discovering mechanisms that underlie susceptibility or resistance to damage. Here, we analyzed skeletal neuromuscular junctions (NMJs) in 16 mouse muscles to seek such differences. We find that muscles respond in one of three ways to aging. In some, including most limb and trunk muscles, age-related alterations to NMJs are progressive and extensive during the second postnatal year. NMJs in other muscles, such as extraocular muscles, are strikingly resistant to …
How To Write An Article: Preparing A Publishable Manuscript!, 2012 Wayne State University
How To Write An Article: Preparing A Publishable Manuscript!, Vinod B. Shidham, Martha B. Pitman, Richard M. Demay
Department of Pathology
Most of the scientific work presented as abstracts (platforms and posters) at various conferences have the potential to be published as articles in peer-reviewed journals. This DIY (Do It Yourself) article on how to achieve that goal is an extension of the symposium presented at the 36th European Congress of Cytology, Istanbul, Turkey (presentation available on net at http://alturl.com/q6bfp). The criteria for manuscript authorship should be based on the ICMJE (International Committee of Medical Journal Editors) Uniform Requirements for Manuscripts. The next step is to choose the appropriate journal to submit the manuscript and review the 'Instructions to …
The Effect Of Load On Movement Coordination During Sled Towing, 2012 University of New England
The Effect Of Load On Movement Coordination During Sled Towing, Michael Lawrence, Daniel Leib, Cara Masterson, Erin Hartigan
Daniel Leib
INTRODUCTION Towing sleds while walking is a popular resistance exercise for the healthy athlete. One reason for the popularity of sled towing is that it is widely believed to be a ‘functional’ exercise. Preliminary research suggests towing while walking can increases lower extremity moment impulses; however whether towing a sled utilizes the same coordination patterns as un-resisted walking is unknown. While altered patterns may not be as relevant to a healthy athlete, sled towing is also sometimes used in the rehabilitation of athletes who sustained a lower extremity injury (anterior cruciate ligament rupture) with the goal of regaining movement symmetry. …
Effects Of Fatigue On Golf Performance, 2012 Boise State University
Effects Of Fatigue On Golf Performance, Daniel J. Leib, Nicholas R. Higdon, W. Holmes Finch, Eric L. Dugan
Daniel Leib
No abstract provided.
Computerized Tomography Providing Definitive Diagnosis Of Colonic Lipoma: A Case Series, 2012 Surgical Trainee
Computerized Tomography Providing Definitive Diagnosis Of Colonic Lipoma: A Case Series, Osama M. Moussa Mr, Sanaa Arshad Dr, Ming Tee Dr, Aref U. Khan Mr, Chelliah R. Selvasekar Mr
Osama M Moussa Mr
Lipomas are common benign mesenchymal tumors. They can develop in virtually all organs throughout the body. Colonic lipomas are uncommon, benign, submucosal adipose tumors that are usually asymptomatic. Large lipomas can cause symptoms such as constipation, abdominal pain, rectal bleeding and intussusception. We report a case series of two colonic submucosal lipomas with different presentations, elaborating the importance of computerised tomography (CT) imaging in the diagnosis.
Optogenetic Stimulation Of The Corticothalamic Pathway Affects Relay Cells And Gabaergic Neurons Differently In The Mouse Visual Thalamus, 2012 Virginia Commonwealth University
Optogenetic Stimulation Of The Corticothalamic Pathway Affects Relay Cells And Gabaergic Neurons Differently In The Mouse Visual Thalamus, Chris W. D. Jurgens, Karen A. Bell, A. Rory Mcquiston, William Guido
Anatomy and Neurobiology Publications
The dorsal lateral geniculate nucleus (dLGN) serves as the primary conduit of retinal information to visual cortex. In addition to retinal input, dLGN receives a large feedback projection from layer VI of visual cortex. Such input modulates thalamic signal transmission in different ways that range from gain control to synchronizing network activity in a stimulus-specific manner. However, the mechanisms underlying such modulation have been difficult to study, in part because of the complex circuitry and diverse cell types this pathway innervates. To address this and overcome some of the technical limitations inherent in studying the corticothalamic (CT) pathway, we adopted …
Early Hearing-Impairment Results In Crossmodal Reorganization Of Ferret Core Auditory Cortex, 2012 Virginia Commonwealth University
Early Hearing-Impairment Results In Crossmodal Reorganization Of Ferret Core Auditory Cortex, M. Alex Meredith, Brian L. Allman
Anatomy and Neurobiology Publications
Numerous investigations of cortical crossmodal plasticity, most often in congenital or early-deaf subjects, have indicated that secondary auditory cortical areas reorganize to exhibit visual responsiveness while the core auditory regions are largely spared. However, a recent study of adult-deafened ferrets demonstrated that core auditory cortex was reorganized by the somatosensory modality. Because adult animals have matured beyond their critical period of sensory development and plasticity, it was not known if adult-deafening and early-deafening would generate the same crossmodal results. The present study used young, ototoxically-lesioned ferrets () that, after maturation (avg. = 173 days old), showed significant hearing deficits (avg. …
The Fit-Hansa Demonstrates Reliability And Convergent Validity Of Functional Performance In Patients With Shoulder Disorders, 2012 McMaster University
The Fit-Hansa Demonstrates Reliability And Convergent Validity Of Functional Performance In Patients With Shoulder Disorders, Prajyot Kumta, Joy C. Macdermid, Saurabh Mehta, Paul W. Stratford
Physical Therapy Faculty Research
Study
DesignPsychometric study design.
Objectives
To assess the test-retest reliability and convergent validity of the Functional Impairment Test-Hand and Neck/Shoulder/Arm (FIT-HaNSA) in patients with shoulder disorders.
Background
Performance tests that assess functional ability of patients with shoulder disorders can provide useful information for making clinical or return-to-activity decisions. No performance-based shoulder test has yet demonstrated sufficient relevance or clinical measurement properties. The FIT-HaNSA examines upper extremity performance during repetitive tasks that emphasize shoulder reaching and static postures and, therefore, has greater relevance for assessing performance.
Methods
Thirty-six patients with shoulder disorders and 65 healthy controls were recruited for the study. …
Is Pilates An Effective Treatment For Improving Functional Disability And Pain In Patients With Nonspecific Low Back Pain?, 2012 Philadelphia College of Osteopathic Medicine
Is Pilates An Effective Treatment For Improving Functional Disability And Pain In Patients With Nonspecific Low Back Pain?, Koren V. Fleming
PCOM Physician Assistant Studies Student Scholarship
OBJECTIVE: The objective of this selective EBM review is to determine whether or not “Is Pilates an effective treatment for improving functional disability and pain in patients with nonspecific low back pain?”
STUDY DESIGN: Review of three English language primary studies, two of which were published in 2006 and the other in 2009.
DATA SOURCES: Three single-blind randomized control trials comparing the Pilates method of treatment to a control group that did not receive Pilates intervention were found using PubMed and EBSCOhost databases.
OUTCOMES MEASURED: Each of the studies had patients participate in Pilates sessions for six to seven weeks. …
Does The Use Of An Oral Lipase Inhibitor (Orlistat) Increase Appetite?, 2012 Philadelphia College of Osteopathic Medicine
Does The Use Of An Oral Lipase Inhibitor (Orlistat) Increase Appetite?, Sandra Boyd
PCOM Physician Assistant Studies Student Scholarship
OBJECTIVE: To determine whether or not Orlistat ingested prior to a meal causes an increased appetite response.
STUDY DESIGN: A Review of three randomized controlled trials studies from 2003-2008 that were in the English language.
DATA RESOURCES: Randomized controlled trials comparing the effect of Orlistat on satiety were found using PubMed, OVID, and Cochrane databases.
OUTOMES MEASURED: Outcomes measured in the studies were: sensation of appetite, hunger, fullness, nausea, bloating, heartburn, belching, epigastric burning, and prospective food consumption. Each study measured individual patient responses using a VAS (visual analogue scale). Demarchi et al (2004) used a gastric barostat to measure …
Is Dabigatran Non-Inferior To Warfarin For The Prevention Of Stroke In Those With Atrial Fibrillation?, 2012 Philadelphia College of Osteopathic Medicine
Is Dabigatran Non-Inferior To Warfarin For The Prevention Of Stroke In Those With Atrial Fibrillation?, Brittany Burlakoff
PCOM Physician Assistant Studies Student Scholarship
OBJECTIVE: The objective of this systematic review is to determine whether or not dabigatran 150 mg twice daily is non-inferior to warfarin for the prevention of stroke in those with atrial fibrillation with similar rates of bleeding events.
STUDY DESIGN: Review of 3 English language primary studies. All three trials were randomized controlled trials which were blinded for those receiving dabigatran and un-blinded for those receiving warfarin.
DATA SOURCES: Articles were found using PUBMED and COCHRANE databases.
OUTCOME MEASURED: The primary outcomes of these studies were either incidence of stroke or systemic embolism and/or major bleeding events.
RESULTS:The RE-LY …
Basic Concepts In Understanding Recovery Of Function In Vestibular Reflex Networks During Vestibular Compensation, 2012 George Washington University
Basic Concepts In Understanding Recovery Of Function In Vestibular Reflex Networks During Vestibular Compensation, Kenna D. Peusner, Mei Shao, Rebecca Reddaway, June C. Hirsch
Anatomy and Regenerative Biology Faculty Publications
Unilateral peripheral vestibular lesions produce a syndrome of oculomotor and postural deficits with the symptoms at rest, the static symptoms, partially or completely normalizing shortly after the lesion due to a process known as vestibular compensation. The symptoms are thought to result from changes in the activity of vestibular sensorimotor reflexes. Since the vestibular nuclei must be intact for recovery to occur, many investigations have focused on studying these neurons after lesions. At present, the neuronal plasticity underlying early recovery from the static symptoms is not fully understood. Here we propose that knowledge of the reflex identity and input–output connections …
Targeting The Cancer Cell Cycle By Cold Atmospheric Plasma, 2012 George Washington University
Targeting The Cancer Cell Cycle By Cold Atmospheric Plasma, Olga Volotskova, Teresa S. Hawley, Mary Ann Stepp, Michael Keidar
Anatomy and Regenerative Biology Faculty Publications
Cold atmospheric plasma (CAP), a technology based on quasi-neutral ionized gas at low temperatures, is currently being evaluated as a new highly selective alternative addition to existing cancer therapies. Here, we present a first attempt to identify the mechanism of CAP action. CAP induced a robust ~2-fold G2/M increase in two different types of cancer cells with different degrees of tumorigenicity. We hypothesize that the increased sensitivity of cancer cells to CAP treatment is caused by differences in the distribution of cancer cells and normal cells within the cell cycle. The expression of γH2A.X (pSer139), an oxidative stress reporter indicating …
Aerosol Therapy For Ventilator-Dependent Patients: Devices, Issues, Selection & Technique, 2012 Georgia State University
Aerosol Therapy For Ventilator-Dependent Patients: Devices, Issues, Selection & Technique, Arzu Ari
Respiratory Therapy Faculty Publications
Aerosol devices have been used to administer inhaled medications since the invention of modern mechanical ventilators. Although many new aerosol devices are available for ventilator-dependent patients, successful aerosol therapy still depends on thorough clinician knowledge of aerosol devices and their proper use. This paper explains the types of aerosol devices available on the market and provides strategies for choosing the right device for optimal treatment of mechanically-ventilated patients.
The Role Of Corticotropin-Releasing Factor In The Behavior And Proinflammatory Activity Of Separated Guinea Pig Pups, 2012 Wright State University
The Role Of Corticotropin-Releasing Factor In The Behavior And Proinflammatory Activity Of Separated Guinea Pig Pups, Vincent Rasahd Alexander
Browse all Theses and Dissertations
Isolation of guinea pig pups in a novel environment first produces active behaviors such as vocalizing and movement; over time, these behaviors wane and pups show characteristic passive responses similar to those produced by increased proinflammatory activity. Further, isolation of pups on two consecutive days has recently been shown to enhance those passive responses on the second day. Endogenous proinflammatory activity is thought to mediate the enhancement (sensitization). An injection of corticotropin-releasing factor (CRF) has been shown to increase passive behavior, possibly by increasing proinflammatory activity. The present study further investigated the role of CRF on proinflammatory activity and behavior …