Asthma,
2020
Illinois Mathematics and Science Academy
Asthma, Rachel Hodge, Brenna Christoffel
Human Diseases Graphic Novels
No abstract provided.
Addison's Disease And Parkinson's Disease,
2020
Illinois Mathematics and Science Academy
Addison's Disease And Parkinson's Disease, Jade Bates, Minju Oh, Megan Ptak
Human Diseases Graphic Novels
No abstract provided.
Patho Graphic Novels: Epilepsy,
2020
Illinois Mathematics and Science Academy
Patho Graphic Novels: Epilepsy, Lily Isibue, Melissa Myint, Laila Walton
Human Diseases Graphic Novels
No abstract provided.
Lung Cancer,
2020
Illinois Mathematics and Science Academy
Lung Cancer, Ahana Narayanan, Maia Peregrino, Moorea Gay
Human Diseases Graphic Novels
No abstract provided.
Celiac Disease,
2020
Illinois Mathematics and Science Academy
Celiac Disease, Maia Peregrino, Ahana Narayanan, Moorea Gay
Human Diseases Graphic Novels
No abstract provided.
Nervous System: Alzheimer’S Disease,
2020
Illinois Mathematics and Science Academy
Nervous System: Alzheimer’S Disease, Krisha Patel, Saachi Kumar, Delicia Chen
Human Diseases Graphic Novels
No abstract provided.
Supersize It! Developing A "Supercytoplast" Through Platelet Fusion,
2020
University of Arkansas, Fayetteville
Supersize It! Developing A "Supercytoplast" Through Platelet Fusion, Taulbee B. Gunter
Animal Science Undergraduate Honors Theses
Stem cell research opens a wide range of possibilities from lab-grown tissues for medical purposes to cloned animals for livestock production. The issue with one of the most popular forms of cell recombination into a stem cell, known as somatic cell nuclear transfer (SCNT), is that it requires an oocyte. The requirement of an oocyte is often the host of public scrutiny for its economic and ethical issues. Platelets may offer a less expensive and more accessible alternative to oocytes as sources of naturally enucleated cells. Thus, the objective of this explorative research project is to isolate and fuse platelets …
The 2019 P-Mig Student Survey Report And Capturing The Undergraduate Perspective Of Physiology Programming,
2020
University of Iowa
The 2019 P-Mig Student Survey Report And Capturing The Undergraduate Perspective Of Physiology Programming, Jennifer Rogers, Jenny L. Mcfarland, Claudia I. Stanescu, Patrick L. Crosswhite, Anne R. Crecelius
Health and Sport Science Faculty Publications
The aim of the 2019 Student Survey was to inform the Physiology Majors Interest Group (PMIG) of characteristics of undergraduates enrolled in physiology courses or degree programs from across the United States, to be used as one input source for development of program-level guidelines. 1389 participants from seven universities completed the 2019 P-MIG Student Survey. 37% reported enrollment in a physiology/human physiology major; allied health related programs were the second most common (24%). 61% of respondents reported attending a community college, the majority of whom enrolled in one or more courses at a community college while in high school (44%). …
Biomechanical Properties Of Land Based And Shallow Water Wait: A Comparative Review Of Literature,
2020
Massey University, Wellington
Biomechanical Properties Of Land Based And Shallow Water Wait: A Comparative Review Of Literature, Mostafa Yaghoubi, Philip Fink, Wyatt H. Page, Sarah P. Shultz
International Journal of Aquatic Research and Education
Aquatic locomotion exercises are frequently used in rehabilitation and cross-training for land-based athletes. Hydrostatic pressure, thermal conductivity and drag force affect a person's ability to move; therefore, it is important to understand differences of biomechanical gait in water vs land. This review investigated biomechanical differences between shallow water and land-based exercises. PubMed, Google Scholar, SPORTDiscus and Scopus were searched; 33 studies included walking forward (27), backward (6) and running (6). Electromyographic amplitude was similar or less in submaximal intensity during aquatic gait, in comparison to on land. At maximal intensities, however, the amplitude was similar (n=5) or higher (n=4) in …
The Effect Of Epa And Dha On Skeletal Muscle Physiology And Energy Balance,
2020
University of Arkansas, Fayetteville
The Effect Of Epa And Dha On Skeletal Muscle Physiology And Energy Balance, Saeed Jebor Ghnaimawi
Graduate Theses and Dissertations
Eicosapentaenoic acid (EPA) and Docosahexaenoic acid (DHA) supplementation commonly suggested during pregnancy confers many health benefits on offspring and more recently improves fetal BAT development and induces myoblast trans-differentiation into adiopocytes through activating PPARs expression. Embryonic myoblast is a highly flexible cell showing great capacity to change its phenotype into adipocyte in response to EPA and DHA supplementation in many in vitro models. However, a little is known about the identity of derived adipocytes, whether, they change into brown or white adipocyte, and in vivo evidence is still missing. Given that the myogeneis process is initiated at the mid of …
A Functional Three-Dimensional Microphysiological Model Of Myeloma Bone Disease,
2020
Seton Hall University
A Functional Three-Dimensional Microphysiological Model Of Myeloma Bone Disease, Richard Visconti
Seton Hall University Dissertations and Theses (ETDs)
Multiple myeloma (MM) is a hematologic cancer caused by a mature B cell neoplasm, or plasmacytoma, that infiltrates the skeleton at several sites. The disease is characterized by uninhibited transformed plasma cell proliferation that disrupts skeletal homeostasis leading to decreased bone modeling and increased bone resorption. Osteolytic lesions (OL) or voids left in the bone, remain long after the treatment of the cancer and indicate disease progression to myeloma bone disease (MBD). Current combinatorial MM therapies inhibit malignant plasma cell proliferation, slow the progression towards MBD, and increase the mean five-year survival rate, but do little to improve osteoblastic function …
Functional Compartmentalization Of Mlck In Fetal Arteries,
2020
Loma Linda University
Functional Compartmentalization Of Mlck In Fetal Arteries, Dane William Sorensen
Loma Linda University Electronic Theses, Dissertations & Projects
Changes in vascular structure and reactivity are amongst the most important that occur during the transition from fetal to newborn life, and are guided by the principle of ensuring adequate coupling of blood flow to metabolism. A clinical consequence of maladaptive fetal vascular adaptation to hypoxia is an increased probability for loss of cerebral autoregulation, increased risk for neonatal encephalopathy, and hypoxicischemic cerebral injury. MLCK is a very specific calcium-calmodulin dependent enzyme, with its only known substrate being MLC20, and is essential for the ability of VSMCs within resistance arteries to appropriately contract or relax in response to changes in …
Lung Epithelial Trpa1 Mediates Lipopolysaccharide-Induced Lung Inflammation In Bronchial Epithelial Cells And Mice,
2020
Taipei Veterans General Hospital, Taiwan
Lung Epithelial Trpa1 Mediates Lipopolysaccharide-Induced Lung Inflammation In Bronchial Epithelial Cells And Mice, Hsin-Kuo Ko, An-Hsuan Lin, Diahn-Warng Perng, Tzong-Shyuan Lee, Yu Ru Kou
Physiology Faculty Publications
Toll-like receptor (TLR) 4 was originally thought to be the sole pattern recognition receptor for lipopolysaccharide (LPS). Transient receptor potential ankyrin 1 (TRPA1), a Ca2+-permeant channel, has been suggested as a non-TLR receptor membrane-bound sensor of LPS. We recently reported that TRPA1 is expressed in lung epithelial cells (LECs) and mediates lung inflammation induced by cigarette smoke. However, the role of TRPA1 in LPS-induced lung inflammation has not been conclusively defined, and its underlying cellular mechanisms remain unclear. In this study, our in vitro results showed that LPS sequentially produced a cascade of events, including the elevation of …
Sexually Dimorphic Oxytocin Receptor-Expressing Neurons In The Anteroventral Periventricular Nucleus Regulates Maternal Behavior,
2020
Louisiana State University and Agricultural and Mechanical College
Sexually Dimorphic Oxytocin Receptor-Expressing Neurons In The Anteroventral Periventricular Nucleus Regulates Maternal Behavior, Kaustubh Sharma
LSU Doctoral Dissertations
The neurohypophysial hormone oxytocin is involved in the regulation of social behaviors, including social recognition, pair bonding, and sex-specific parental behaviors in a variety of species. Oxytocin triggers these social behaviors by binding to oxytocin receptors (OXTR) in various parts of the brain. Oxytocin-induced sex-typical behavior, therefore, suggests a sexual dimorphic distribution of OXTR in the brain. In recent years, the oxytocin system in the brain received tremendous attention as a potential pharmacological target for treatment of many psychiatric disorders, such as anxiety, autism spectrum disorders, and even sex-specific psychiatric disorder like postpartum depression (PPD). An important problem and a …
The Combined Effects Of Exercise-Induced Muscle Damage And Heat Stress On Acute Kidney Stress And Heat Strain During Subsequent Endurance Exercise,
2020
University of New Mexico - Main Campus
The Combined Effects Of Exercise-Induced Muscle Damage And Heat Stress On Acute Kidney Stress And Heat Strain During Subsequent Endurance Exercise, Zidong Li
Health, Exercise, and Sports Sciences ETDs
Purpose: The purpose of this study was to investigate the combined effect of downhill running and heat stress on muscle damage, as well as on heat strain and kidney stress during subsequent endurance exercise in the heat. Methods: Using a crossover design and randomized order, ten non-heat-acclimated, physically active males completed downhill running in a cool (EIMD in Cool) and hot (EIMD in Hot) environment followed by an exercise-heat stress (HS) test after 3-hour seated rest. Core temperature, heart rate, thermal sensation and ratings of perceived exertion were recorded throughout each exercise session. Blood and urine samples were collected at …
Mathematical Modelling Of Temperature Effects On The Afd Neuron Of Caenorhabditis Elegans,
2020
Illinois State University
Mathematical Modelling Of Temperature Effects On The Afd Neuron Of Caenorhabditis Elegans, Zachary Mobille, Rosangela Follmann, Epaminondas Rosa
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Stochastic Modeling Of Ovarian Follicle Growth In Adult Female Rats,
2020
Illinois State University
Stochastic Modeling Of Ovarian Follicle Growth In Adult Female Rats, Zhaozhi Li
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
No Changes In Appetite-Related Hormones Following Swimming And Cycling Exercise Interventions In Adults With Obesity,
2020
The University of Texas at Austin
No Changes In Appetite-Related Hormones Following Swimming And Cycling Exercise Interventions In Adults With Obesity, Brandon G. Fico, Mohammed Alkatan, Hirofumi Tanaka
International Journal of Exercise Science
International Journal of Exercise Science 13(2): 1819-1825, 2020. Swimming is a favorable and ideal modality of exercise for individuals with obesity and arthritis as it encompasses a minimal weight-bearing stress and a reduced heat load. However, the available evidence indicates that regular swimming may not be effective in reducing body weight and body fatness. A current hypothesis is that exercise in cold water stimulates appetite. We determined the effect of swimming training on appetite-related hormones. Thirty-nine adults with obesity and osteoarthritis were randomly assigned to 12 weeks of supervised swimming or cycling training. In the initial few weeks, participants exercised …
Cardiovascular And Muscular Response To No Load Exercise With Blood Flow Restriction,
2020
University of South Florida
Cardiovascular And Muscular Response To No Load Exercise With Blood Flow Restriction, Wenyuan Zhu, Noam Yitzchaki, Tayla E. Kuehne, Ryo Kataoka, Kevin Mattocks, Samuel L. Buckner
International Journal of Exercise Science
International Journal of Exercise Science 13(2): 1807-1818, 2020. Changes in muscle thickness (MT), isometric torque, and arterial occlusion pressure (AOP) were examined following four sets of twenty unilateral elbow flexion exercise. Participants performed four sets of maximal voluntary contractions with no external load throughout a full range of motion of a bicep curl with and without the application of blood flow restriction (BFR). For torque there was an interaction (p = 0.012). The BFR condition had lower torque following exercise (56.07 ± 17.78 Nm) compared to the control condition (58.67 ± 19.06 Nm). For MT, there was a main …
Ceramide Analog [18F]F-Hpa-12 Detects Sphingolipid Disbalance In The Brain Of Alzheimer’S Disease Transgenic Mice By Functioning As A Metabolic Probe,
2020
University of Kentucky
Ceramide Analog [18F]F-Hpa-12 Detects Sphingolipid Disbalance In The Brain Of Alzheimer’S Disease Transgenic Mice By Functioning As A Metabolic Probe, Simone M. Crivelli, Daan Van Kruining, Qian Luo, Jo A. A. Stevens, Caterina Giovagnoni, Andreas Paulus, Matthias Bauwens, Dusan Berkes, Helga E. De Vries, Monique T. Mulder, Jochen Walter, Etienne Waelkens, Rita Derua, Johannes V. Swinnen, Jonas Dehairs, Felix M. Mottaghy, Mario Losen, Erhard Bieberich, Pilar Martinez-Martinez
Physiology Faculty Publications
The metabolism of ceramides is deregulated in the brain of Alzheimer’s disease (AD) patients and is associated with apolipoprotein (APO) APOE4 and amyloid-β pathology. However, how the ceramide metabolism changes over time in AD, in vivo, remains unknown. Distribution and metabolism of [18F]F-HPA-12, a radio-fluorinated version of the ceramide analog N-(3-hydroxy-1-hydroxymethyl-3-phenylpropyl) dodecanamide, was investigated in the brain of AD transgenic mouse models (FAD) on an APOE4 or APOE3 genetic background, by positron emission tomography and by gamma counter. We found that FAD mice displayed a higher uptake of [18F]F-HPA-12 in the brain, independently from the APOE4 …
