Lung Epithelial Trpa1 Mediates Lipopolysaccharide-Induced Lung Inflammation In Bronchial Epithelial Cells And Mice,
2020
Taipei Veterans General Hospital, Taiwan
Lung Epithelial Trpa1 Mediates Lipopolysaccharide-Induced Lung Inflammation In Bronchial Epithelial Cells And Mice, Hsin-Kuo Ko, An-Hsuan Lin, Diahn-Warng Perng, Tzong-Shyuan Lee, Yu Ru Kou
Physiology Faculty Publications
Toll-like receptor (TLR) 4 was originally thought to be the sole pattern recognition receptor for lipopolysaccharide (LPS). Transient receptor potential ankyrin 1 (TRPA1), a Ca2+-permeant channel, has been suggested as a non-TLR receptor membrane-bound sensor of LPS. We recently reported that TRPA1 is expressed in lung epithelial cells (LECs) and mediates lung inflammation induced by cigarette smoke. However, the role of TRPA1 in LPS-induced lung inflammation has not been conclusively defined, and its underlying cellular mechanisms remain unclear. In this study, our in vitro results showed that LPS sequentially produced a cascade of events, including the elevation of …
Sexually Dimorphic Oxytocin Receptor-Expressing Neurons In The Anteroventral Periventricular Nucleus Regulates Maternal Behavior,
2020
Louisiana State University and Agricultural and Mechanical College
Sexually Dimorphic Oxytocin Receptor-Expressing Neurons In The Anteroventral Periventricular Nucleus Regulates Maternal Behavior, Kaustubh Sharma
LSU Doctoral Dissertations
The neurohypophysial hormone oxytocin is involved in the regulation of social behaviors, including social recognition, pair bonding, and sex-specific parental behaviors in a variety of species. Oxytocin triggers these social behaviors by binding to oxytocin receptors (OXTR) in various parts of the brain. Oxytocin-induced sex-typical behavior, therefore, suggests a sexual dimorphic distribution of OXTR in the brain. In recent years, the oxytocin system in the brain received tremendous attention as a potential pharmacological target for treatment of many psychiatric disorders, such as anxiety, autism spectrum disorders, and even sex-specific psychiatric disorder like postpartum depression (PPD). An important problem and a …
The Combined Effects Of Exercise-Induced Muscle Damage And Heat Stress On Acute Kidney Stress And Heat Strain During Subsequent Endurance Exercise,
2020
University of New Mexico - Main Campus
The Combined Effects Of Exercise-Induced Muscle Damage And Heat Stress On Acute Kidney Stress And Heat Strain During Subsequent Endurance Exercise, Zidong Li
Health, Exercise, and Sports Sciences ETDs
Purpose: The purpose of this study was to investigate the combined effect of downhill running and heat stress on muscle damage, as well as on heat strain and kidney stress during subsequent endurance exercise in the heat. Methods: Using a crossover design and randomized order, ten non-heat-acclimated, physically active males completed downhill running in a cool (EIMD in Cool) and hot (EIMD in Hot) environment followed by an exercise-heat stress (HS) test after 3-hour seated rest. Core temperature, heart rate, thermal sensation and ratings of perceived exertion were recorded throughout each exercise session. Blood and urine samples were collected at …
Mathematical Modelling Of Temperature Effects On The Afd Neuron Of Caenorhabditis Elegans,
2020
Illinois State University
Mathematical Modelling Of Temperature Effects On The Afd Neuron Of Caenorhabditis Elegans, Zachary Mobille, Rosangela Follmann, Epaminondas Rosa
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Stochastic Modeling Of Ovarian Follicle Growth In Adult Female Rats,
2020
Illinois State University
Stochastic Modeling Of Ovarian Follicle Growth In Adult Female Rats, Zhaozhi Li
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
No Changes In Appetite-Related Hormones Following Swimming And Cycling Exercise Interventions In Adults With Obesity,
2020
The University of Texas at Austin
No Changes In Appetite-Related Hormones Following Swimming And Cycling Exercise Interventions In Adults With Obesity, Brandon G. Fico, Mohammed Alkatan, Hirofumi Tanaka
International Journal of Exercise Science
International Journal of Exercise Science 13(2): 1819-1825, 2020. Swimming is a favorable and ideal modality of exercise for individuals with obesity and arthritis as it encompasses a minimal weight-bearing stress and a reduced heat load. However, the available evidence indicates that regular swimming may not be effective in reducing body weight and body fatness. A current hypothesis is that exercise in cold water stimulates appetite. We determined the effect of swimming training on appetite-related hormones. Thirty-nine adults with obesity and osteoarthritis were randomly assigned to 12 weeks of supervised swimming or cycling training. In the initial few weeks, participants exercised …
Cardiovascular And Muscular Response To No Load Exercise With Blood Flow Restriction,
2020
University of South Florida
Cardiovascular And Muscular Response To No Load Exercise With Blood Flow Restriction, Wenyuan Zhu, Noam Yitzchaki, Tayla E. Kuehne, Ryo Kataoka, Kevin Mattocks, Samuel L. Buckner
International Journal of Exercise Science
International Journal of Exercise Science 13(2): 1807-1818, 2020. Changes in muscle thickness (MT), isometric torque, and arterial occlusion pressure (AOP) were examined following four sets of twenty unilateral elbow flexion exercise. Participants performed four sets of maximal voluntary contractions with no external load throughout a full range of motion of a bicep curl with and without the application of blood flow restriction (BFR). For torque there was an interaction (p = 0.012). The BFR condition had lower torque following exercise (56.07 ± 17.78 Nm) compared to the control condition (58.67 ± 19.06 Nm). For MT, there was a main …
Ceramide Analog [18F]F-Hpa-12 Detects Sphingolipid Disbalance In The Brain Of Alzheimer’S Disease Transgenic Mice By Functioning As A Metabolic Probe,
2020
University of Kentucky
Ceramide Analog [18F]F-Hpa-12 Detects Sphingolipid Disbalance In The Brain Of Alzheimer’S Disease Transgenic Mice By Functioning As A Metabolic Probe, Simone M. Crivelli, Daan Van Kruining, Qian Luo, Jo A. A. Stevens, Caterina Giovagnoni, Andreas Paulus, Matthias Bauwens, Dusan Berkes, Helga E. De Vries, Monique T. Mulder, Jochen Walter, Etienne Waelkens, Rita Derua, Johannes V. Swinnen, Jonas Dehairs, Felix M. Mottaghy, Mario Losen, Erhard Bieberich, Pilar Martinez-Martinez
Physiology Faculty Publications
The metabolism of ceramides is deregulated in the brain of Alzheimer’s disease (AD) patients and is associated with apolipoprotein (APO) APOE4 and amyloid-β pathology. However, how the ceramide metabolism changes over time in AD, in vivo, remains unknown. Distribution and metabolism of [18F]F-HPA-12, a radio-fluorinated version of the ceramide analog N-(3-hydroxy-1-hydroxymethyl-3-phenylpropyl) dodecanamide, was investigated in the brain of AD transgenic mouse models (FAD) on an APOE4 or APOE3 genetic background, by positron emission tomography and by gamma counter. We found that FAD mice displayed a higher uptake of [18F]F-HPA-12 in the brain, independently from the APOE4 …
Lower Limb Graduated Compression Garments Modulate Autonomic Nervous System And Improve Post-Training Recovery Measured Via Heart Rate Variability,
2020
University of California, Los Angeles
Lower Limb Graduated Compression Garments Modulate Autonomic Nervous System And Improve Post-Training Recovery Measured Via Heart Rate Variability, Jonathan Hu, Jonathan D. Browne, Jaxon T. Baum, Anthony Robinson, Michael T. Arnold, Sean P. Reid, Eric V. Neufeld, Brett A. Dolezal
International Journal of Exercise Science
International Journal of Exercise Science 13(7): 1794-1806, 2020. Prior studies have examined the benefits of graduated compression garments (GCG) with regards to diverse exercise regimens; however, the relationship between GCG and the autonomic nervous system (ANS) has not been fully explored. The aim of this study was to examine Heart Rate Variability (HRV) trends—a proxy for ANS modulation—in response to donning GCG during a progressive overload training regimen designed to induce overtraining. Ten college-aged male novice runners were recruited for the 8-week crossover study. After three weeks of monitored free living, participants were randomized and blinded to an intervention group …
Short Term High-Repetition Back Squat Protocol Does Not Improve 5-Km Run Performance,
2020
Indiana University
Short Term High-Repetition Back Squat Protocol Does Not Improve 5-Km Run Performance, Matthew J. Barenie, Jordan T. Domenick, Jason E. Bennett, George G. Schweitzer, Paulina Shetty, Edward P. Weiss
International Journal of Exercise Science
International Journal of Exercise Science 13(7): 1770-1782, 2020. The purpose of this study was to evaluate the hypothesis that a novel high-repetition, low-resistance back squat training protocol, designed to stimulate high-intensity interval training, improves 5-km run performance. Fifteen runners [4 male, 11 female; 150 + minutes of endurance exercise/week; age = 22.7 ± 2.0 y; 21.5 ± 2.2 kg/m2 BMI] in this single-group test-retest design completed two weeks of back squats consisting of three sets of 15-24 repetitions at 60% of estimated one-repetition max (1RM), three times per week (1-2 days of rest between sessions). Outcome tests included a …
Energy Expenditure And Muscular Recruitment Patterns Of Riding A Novel Electrically Powered Skateboard,
2020
University of California, Los Angeles
Energy Expenditure And Muscular Recruitment Patterns Of Riding A Novel Electrically Powered Skateboard, Anthony J. Robinson, Robert P. Carter, Jonathan D. Browne, Jonathan Hu, Michael T. Arnold, Jaxon T. Baum, Eric V. Neufeld, Brett A. Dolezal
International Journal of Exercise Science
International Journal of Exercise Science 13(4): 1783-1793, 2020. Analysis of metabolic gas exchange and muscular output measures have enabled researchers to index activity intensity and energy expenditure for a myriad of exercises. However, there is no current research that investigates the physiological demands of riding electrically powered skateboards. The aim of this study was to measure the energetic cost and muscular trends of riding a novel electrically powered skateboard engineered to emulate snowboarding on dry-land. While riding the skateboard, eight participants (aged 21-37 years, 1 female) donned a portable breath-by-breath gas analyzer to measure energy expenditure (mean = 12.5, …
Heavy Is The Head That Wears The Crown: Black Men’S Perspective On Harmful Effects Of Hair Product Use And Breast Cancer Risk,
2020
Chapman University
Heavy Is The Head That Wears The Crown: Black Men’S Perspective On Harmful Effects Of Hair Product Use And Breast Cancer Risk, Dede K. Teteh, Marissa Chan, Bing Turner, Brian Hedgeman, Marissa Ericson, Phyllis Clark, Eudora Mitchell, Emily Barrett, Adana Llanos, Rick Kittles, Susanne Montgomery
Health Sciences and Kinesiology Faculty Articles
Racial disparities in breast cancer are well-documented, and Black women assume a disproportionate burden of breast cancer mortality. Black women also commonly use hair products containing endocrine disrupting chemicals (EDCs) more often at an increased rate, as compared to other racial/ethnic groups. Emerging findings have reported the use of hair and other personal care products containing EDCs may contribute to breast cancer risk. While some sociocultural perspectives about hair and identity have been explored, the role of beauty expectations upheld by males has not been studied. Through a community-based participatory methodology, we explored perceptions and beliefs held by Black men …
A Comparison Of United States Marine Corps Physical Fitness Test And Combat Fitness Test Results,
2020
Southern Utah University
A Comparison Of United States Marine Corps Physical Fitness Test And Combat Fitness Test Results, Marc Keefer, Mark Debeliso
International Journal of Exercise Science
International Journal of Exercise Science 13(4): 1741-1755, 2020. The United States Marines Corps (USMC) have installed a Physical Fitness Test (PFT) to measure physical fitness levels and a Combat Fitness Test (CFT) to assess a Marine’s functional fitness as it relates to the demands of combat operations. The PFT involves three events; pull-ups/push-ups (PU), two-minute abdominal crunches/sit-ups (AC), and a timed three-mile run (RUN). The CFT also involves three events; Movement to Contact (MTC), two-minute Ammunition Lift (AL), and Maneuver-Under-Fire (MANUF). It is of interest to determine if the PFT and CFT are both necessary. As such, the purpose of …
Metabolic Flexibility And Weight Status May Contribute To Inter-Individual Changes In Breastmilk Lipid Content In Response To An Acute Bout Of Exercise: Preliminary Findings From A Pilot Study,
2020
University of Tennessee Graduate School of Medicine
Metabolic Flexibility And Weight Status May Contribute To Inter-Individual Changes In Breastmilk Lipid Content In Response To An Acute Bout Of Exercise: Preliminary Findings From A Pilot Study, Jill M. Maples, Charlotte Mccarley, Maire M. Blankenship, Kristin Yoho, K.Paige Johnson, Kimberly B. Fortner, Rachel A. Tinius
International Journal of Exercise Science
International Journal of Exercise Science 13(2): 1756-1769, 2020. The purposes of this pilot study were to describe changes in breastmilk lipid content in response to an acute bout of moderate intensity exercise and to explore maternal metabolic health factors, including metabolic flexibility, which may impact this change. A cross-sectional, observational, pilot study design was performed in 14 women between 4 and 6 months postpartum. Whole body fasting lipid oxidation was assessed, a standardized high-fat breakfast was consumed, and lipid oxidation was again measured 120-minutes post-meal. Metabolic flexibility was determined by comparing the change in lipid oxidation before and after the …
New Multisite Bioelectrical Impedance Device Compared To Hydrostatic Weighing And Skinfold Body Fat Methods,
2020
University of New Mexico
New Multisite Bioelectrical Impedance Device Compared To Hydrostatic Weighing And Skinfold Body Fat Methods, Andrew D. Wells, Bryanne N. Bellovary, Jonathan M. Houck, Jeremy B. Ducharme, Abdulaziz Abdulrahman A. Masoud, Ann L. Gibson, Christine M. Mermier
International Journal of Exercise Science
International Journal of Exercise Science 13(4): 1718-1728, 2020. The purpose of this study was to compare the Skulpt Chisel™ to seven-site skinfold (SKF) and hydrostatic weighing (HW) body fat percentage (%BF) estimates. Twenty-six participants (aged 24 ± 4 years; BMI 23.1 ± 3.5 kg∙m-2) were assessed. Significant differences in %BF estimates were found for all methodological pairings; p < 0.05. The SKF method underestimated %BF compared to HW (-2.52 ± 3.42 %BF). The Skulpt Chisel™ overestimated %BF compared to both HW (3.38 ± 6.10 %BF) and SKF (5.90 ± 5.26 %BF). Limits of agreement comparing HW to Skulpt Chisel™ indicated a difference between 95% confidence interval bounds (Upper bound: 5.84 %BF, Lower bound 0.92 %BF) and for HW to SKF (Upper bound: -1.14 %BF, Lower bound: -3.91 %BF). Regression analysis showed no significant bias for any methodological pairing; (p > 0.05). In conclusion, the Skulpt Chisel™ method should be used with caution when evaluating %BF of adults with similar demographics reported in this study.
The Effects Of Acute Anaerobic Exercise On The Cardiovascular And Metabolic Response To The Cold Pressor Test In Healthy Adult Males,
2020
Pan Am Clinic Foundation
The Effects Of Acute Anaerobic Exercise On The Cardiovascular And Metabolic Response To The Cold Pressor Test In Healthy Adult Males, Marc P. Morissette, Dean M. Cordingley, Todd A. Duhamel, Jeff R. S. Leiter
International Journal of Exercise Science
International Journal of Exercise Science 13(3): 1729-1740, 2020. Little is known about the physiological response to the cold pressor test (CPT) when in a clinically-induced state of autonomic nervous system (ANS) imbalance, despite its utility in various disease- and injury-states. To date, research in this area is limited to acute aerobic and isometric exercise, with a paucity of research investigating the effects of anaerobic exercise on the physiological response to the CPT. Therefore, the purpose of our study was to assess the effects of the Wingate anaerobic cycle test (WAT) on cardiovascular (CV) and metabolic recovery following the CPT in …
Use Of Heart Rate Index To Predict Oxygen Uptake – A Validation Study,
2020
The College of New Jersey
Use Of Heart Rate Index To Predict Oxygen Uptake – A Validation Study, Jie Kang, Nicholas A. Ratamess, Avery D. Faigenbaum, Jill A. Bush-Wallace, Christopher Roser, Devyn Montemarano, Hannah Mercado, Morgan Choma, Christian Mendez, Matthew Pollock
International Journal of Exercise Science
International Journal of Exercise Science 13(7): 1705-1717, 2020. An equation that uses heart rate index (HRI) defined as HR/HRrest to predict oxygen uptake (VO2) in METs (e.g., METs = 6 × HRI ‒ 5) has been developed retrospectively from aggregate data of 60 published studies. However, the prediction error of this model as used by an individual has not been established. Therefore, the purpose of this study was to examine the predictive validity of the HRI equation by comparing submaximal and maximal VO2 predicted by the equation (VO2-Pred) with that measured by indirect calorimetry (VO …
Relationships Of Lower-Body Power Measures To Sprint And Change Of Direction Speed Among Ncaa Division Ii Women’S Lacrosse Players: An Exploratory Study,
2020
University of Colorado Colorado Springs
Relationships Of Lower-Body Power Measures To Sprint And Change Of Direction Speed Among Ncaa Division Ii Women’S Lacrosse Players: An Exploratory Study, Emily Kulakowski, Robert G. Lockie, Quincy Johnson, Keston Lindsay, J. Jay Dawes
International Journal of Exercise Science
International Journal of Exercise Science 13(6): 1667-1676, 2020. This study sought to determine if significant relationships exist between lower-body power measures to sprint and change of direction speed (CODS) in Division II collegiate women’s lacrosse athletes. Archived data for 17 NCAA Division II female lacrosse athletes was provided to the investigators for analysis. Jumping performance was assessed using a countermovement jump (CMJ), squat jump (SJ), and standing broad jump (SBJ). Sprint speed was measured at 10m and 30m, of a 30m sprint. CODS was evaluated using a T-Test (TT), a modified T-Test (MTT), and the 5-0-5 Agility Test (5-0-5). No …
No Change In Executive Function Or Stress Hormones Following A Bout Of Moderate Treadmill Exercise In Preadolescent Children,
2020
California Polytechnic State University - San Luis Obispo
No Change In Executive Function Or Stress Hormones Following A Bout Of Moderate Treadmill Exercise In Preadolescent Children, Brian T. Ebisuzaki, Nicholas D. Riemen, Kory M. Bettencourt, Lupita M. Gonzalez, Kelly A. Bennion, Cory J. Greever
International Journal of Exercise Science
International Journal of Exercise Science 13(5): 1650-1666, 2020. Several studies suggest that acute bouts of exercise improve executive function in preadolescent children. However, the mechanisms underlying these effects are not completely understood. Specifically, no studies have examined the relationship between the stress hormone response to exercise and improvements in executive function in preadolescent children. The purpose of this study was to examine the effects of a bout of moderate intensity exercise versus rest on working memory (List Sorting Working Memory Task) and selective inhibition/attention (Eriksen flanker task) in preadolescent children, as well as to investigate whether changes in stress hormones …
Multi-Joint Vs Single-Joint Resistance Exercises Induce A Similar Strength Increase In Trained Men: A Randomized Longitudinal Crossover Study,
2020
Methodist University of Piracicaba
Multi-Joint Vs Single-Joint Resistance Exercises Induce A Similar Strength Increase In Trained Men: A Randomized Longitudinal Crossover Study, Felipe Alves Brigatto, Júlio Benvenutti Bueno De Camargo, Witter Felipe De Ungaro, Moisés Diego Germano, Paulo Henrique Marchetti, Marcelo Saldanha Aoki, Tiago Volpi Braz, Charles Ricardo Lopes
International Journal of Exercise Science
International Journal of Exercise Science 13(4): 1677-1690, 2020. The type of exercise is a relevant resistance training-variable that might be manipulated in order to induce significant increases in muscle strength. The aim of this study was to analyze the influence of multi-joint vs single-joint resistance exercises on maximal strength. Sixteen resistance-trained men (age: 23.1 ± 4.4 years; body mass: 86.0 ± 12.8; height: 177.9 ± 6.4 cm; training experience: 4.2 ± 3.4 years) performed one of the following training protocols for six weeks: MULTI, consisting of only multi-joint exercises or SINGLE, consisting of only single-joint exercises. Subjects were then submitted …
