Physiology Commons^™

Comparison Of Post-Activation Potentiation Methods On Power And Sprint Acceleration, Aaron Piper

Electronic Theses and Dissertations

Post-activation potentiation (PAP) is a stimulus used to enhance performance by performing specific interventions prior to subsequent explosive movements. The purpose of this study was to determine the effect of different PAP methods on power and sprint acceleration in resistance trained, college-aged men and women. A total of 13 subjects participated in the study. After determining back squat 1 repetition max, subjects returned for testing on separate days to complete one of four interventions (dynamic resistance, weighted plyometric, isometric, or control) in a randomized order. A standardized warmup was given, followed by a baseline countermovement jump (CMJ) and 20-meter sprint. …

Comparative Plasma Proteomics In Muscle Atrophy Induced By Cancer Cachexia And Hindlimb Unloading, Kirsten Rene Dunlap

Graduate Theses and Dissertations

Introduction: Muscle atrophy results from a dysfunction in protein turnover that leads to loss of mass and function and occurs concurrently with multiple pathologies such as cancer and extended bed rest. Atrophy reduces overall quality of life while increasing morbidity and mortality. Currently, efficacious therapeutic interventions to treat and prevent muscle wasting in all its forms are lacking, however if conserved mechanisms can be identified between wasting conditions, this would aid in the development of multipurpose therapeutics to ameliorate this pathology. Purpose: To examine circulating factors present across atrophic pathologies. Methods: 35 male C57BL/6J mice were assigned to hindlimb unloading …

The Effects Of Salinity On Zootechnical Performance Of Spotted Seatrout (Cynoscion Nebulosus) In Recirculating Aquaculture Systems, Eric Gigli

Master's Theses

The spotted seatrout (Cynoscion nebulosus) is a euryhaline finfish candidate for marine aquaculture in the northern Gulf of Mexico. Aquaculture of this species currently uses salinities of 25 psu or greater making production challenging in areas where high salinity water is not available. This study aimed to document the effects of salinity on zootechnical performance of spotted seatrout embryos, early larvae, and juveniles in recirculating aquaculture systems to assist with the development of protocols for low salinity culture.

Embryos obtained from a volitional spawn at 29 psu were incubated at three salinities (12.5, 18.75, or 25 psu) until …

Effects Of A 3-Week High-Fat-Low-Carbohydrate Diet On Lipid And Glucose Profiles In 8 Experienced, Middle-Age Male Runners, Eric K. O'Neal, Ashton F. Smith, Alexander J. Heatherly, Lauren G. Killen, Hunter S. Waldman, Angela Hollingsworth, Yunsuk Koh

International Journal of Exercise Science

International Journal of Exercise Science 12(2): 786-799, 2019. This study examined glucose and lipid marker responses following a 3-week, ad libitum low-carbohydrate-high-fat diet (LCHF; ~70% kcals from fat, <50 g/day of net carbohydrates) versus the habitual mixed macronutrient diet (HMD) of eight middle-age, trained male runners (40 ±10 years; V̇O₂peak = 49 ±4 mL·kg^-1·min^-1). Blood was drawn at 0600 from an antecubital vein after an overnight fast under conditions of no exercise/ heat stress (NEXH; 48 h of restriction from intense exercise) or 24-h after exercise/heat stress (EXH; 60 min run in hot conditions plus 5-km time trial) for both dietary conditions. Glucose improvement during LCHF approached but did not reach statistical significance (p = 0.07). …

Obesity Affects Submaximal Oxygen Uptake-Heart Rate Relationship And Exercise Economy Differently In Pre And Postpubescent Boys And Girls, Eric Rivas

International Journal of Exercise Science

International Journal of Exercise Science 12(3): 748-763, 2019. The purpose of this study was to develop regression equations for estimating the intensity of the exercise work rate (relative peak oxygen uptake-heart rate [%VO₂-HR]) and the metabolic energy expenditure (MEE) for exercise prescription and rehabilitation medicine that are specific to children. This study took into account that the specific data in terms of obesity, sex, and pubertal status are currently unavailable. Our hypothesis was that obesity would affect the submaximal exercise the oxygen uptake (VO₂), heart rate (HR), and metabolic energy expenditure (MEE), and exercise economy (ExEco). …

Too Much Workplace Sitting: A Brief Historical Perspective, Raymond Jones, Daniel P. Credeur, Stephanie M. Mccoy

International Journal of Exercise Science

International Journal of Exercise Science 12(2): 777-785, 2019. Sedentary behavior is a risk factor for the development of chronic diseases, especially those of cardiovascular and metabolic origins. Prolonged sitting is one of the most common sedentary behaviors among adults. Individuals sit for hours every day for several reasons, including work and or physical limitations. Historical accounts regarding the negative health effects of prolonged sitting began with early epidemiological studies, which sparked a breakout of research examining this behavior in the workplace setting. Understanding the risks associated with prolonged workplace sitting is important when considering workplace interventions, such as sit-stand workstations. …

Cardiovascular Disease Risk Factors And Physical Fitness In Volunteer Firefighters, Zachary T. Martin, Rebecca A. Schlaff, Jade K. Hemenway, Jillian R. Coulter, Jeremy L. Knous, John E. Lowry, Joshua J. Ode

International Journal of Exercise Science

International Journal of Exercise Science 12(2): 764-776, 2019. Forty-seven percent of volunteer firefighter line of duty deaths are caused by cardiovascular events. Aggressive cardiovascular disease (CVD) risk factor reduction and improved physical fitness could reduce CVD mortality within this population. We assessed CVD risk factors and physical fitness in a large cohort of volunteer firefighters to help establish a health and fitness profile of this population, which may serve as evidence for the need to initiate programs aimed at reducing morbidity and mortality caused by CVD in the volunteer fire service. Seventy-four male volunteer firefighters were assessed for eight CVD …

Effects Of Whole-Body Vibration On Flexibility And Stiffness: A Literature Review, Brannen Fowler, Turner Palumbo, Brent Feland, Jonathan Blotter

International Journal of Exercise Science

International Journal of Exercise Science 12(3): 735-747, 2019. The effects of whole-body vibration (WBV) on flexibility and muscle stiffness are focused areas of research. Many studies have been performed over a large range of vibratory conditions and have reported varied results on effectiveness. When reviewing the published literature, it is difficult to track the vibration parameters that have positive effects and which have negative or no effects. In writing this paper,over 80 articles were evaluated, 24 of which met the inclusion requirements. The data gathered in the articles were used to develop charts that illustrate the vibration conditions that elicit …

The Impact Of Power Training On Balance And Visual Feedback Removal, Juliana Bouton

Senior Honors Theses

Because power training has been known to augment stability, the purpose of this study was to assess whether the removal of visual input affects lower limb muscle power production in young women who are resistance trained to the same degree it affects the untrained. This provided insight as far as the need for resistance training protocols in a largely untrained visually impaired population. To study this, fourteen college-aged female participants (18-23 years) performed a seated double-leg press on a leg sled machine, isolating power production of the lower limbs. After establishing baselines, which involved finding an average of power produced …

Comparison Of Steady State Exercise And Interval Training On Pitching Performance In Collegiate Baseball Players: A Pilot Study, Robert Rabena, Ryan Moran

International Journal of Exercise Science

International Journal of Exercise Science 12(6): 726-734, 2019. Traditionally, a baseball pitcher’s in-season conditioning between starts has consisted of steady state exercise. Little to no research exists on the effects of interval training on pitching performance. The purpose of this study was to examine the difference between steady state exercise (SSE) and interval training (IT) on exercise and pitching performance in collegiate baseball pitchers following an 11-week program. A total of 13 collegiate baseball pitchers were randomly assigned to either the SSE or IT group and tested pre- and post-season on a one-mile run, 30-m sprint, pitching velocity, walks plus …

The Influence Of A Slow-Breathing Protocol On Heart Rate And Blood Pressure From Exercise In Moderately Trained Females, Emily L. Zumbro, Greg A. Ryan, Stephen J. Rossi, John L. Dobson

International Journal of Exercise Science

International Journal of Exercise Science 12(2): 714-725, 2019. Heart rate recovery (HRR) and blood pressure recovery (BPR) from exercise are both important indicators of health and fitness and are strongly associated with cardiovascular disease. The purpose of this study was to compare the effects of a slow-breathing technique, upright passive recovery (PASS), and active recovery (ACT) on HRR and BPR from exercise. Nine moderately trained, college-aged (20.22 ± 0.97 yrs) female participants cycled three times on an ergometer for 15 mins at 70% of their heart rate maximum (HR_max), each of which was followed by one of three …

Endothelial, Cardiovascular, And Performance Responses To L-Arginine Intake And Resistance Exercise, Daniel M. Streeter, Kara A. Trautman, Tylor W. Bennett, Lauren E. Mcintosh, James W. Grier, Sherri N. Stastny, Kyle J. Hackney

International Journal of Exercise Science

International Journal of Exercise Science 12(2): 701-713, 2019. The purpose of this study was to examine the acute endothelial, cardiovascular, and performance responses to L-arginine intake by assessing flow-mediated dilation (FMD) and various indicators (e.g., heart rate, heart rate variability (HRV), blood pressure, torque) both before and after resistance exercise. Thirty (15 male, 15 female) physically active participants (mean ± SD: age 20.4 ± 1.8 years, height 176.9 ± 10.2 cm, body mass 76.0 ± 12.2 kg) volunteered for a randomized, cross-over, double-blind, placebo-controlled clinical trial. Participants completed five sets of elbow extension-flexion exercise after consumption of either 3 g …

Bovine Milk Extracellular Vesicles (Evs) Modification Elicits Skeletal Muscle Growth In Rats, Hailey A. Parry, Christopher Brooks Mobley, Petey W. Mumford, Matthew A. Romero, Cody T. Haun, Yufeng Zhang, Paul A. Roberson, Janos Zempleni, Arny A. Ferrando, Ivan J. Vechetti Jr., John J. Mccarthy, Kaelin C. Young, Michael D. Roberts, Andreas N. Kavazis

Physiology Faculty Publications

The current study investigated how bovine milk extracellular vesicles (EVs) affected rotarod performance and biomarkers of skeletal muscle physiology in young, growing rats. Twenty-eight-day Fisher 344 rats were provided an AIN-93G-based diet for 4 weeks that either remained unadulterated [EVs and RNA-sufficient (ERS; n = 12)] or was sonicated [EVs and RNA-depleted (ERD; n = 12)]. Prior to (PRE) and on the last day of the intervention (POST), animals were tested for maximal rotarod performance. Following the feeding period, the gastrocnemius muscle was analyzed at the histological, biochemical, and molecular levels and was also used to measure mitochondrial function and …

Extracellular Vesicles As Biological Shuttles For Targeted Therapies., Stefania Raimondo, Gianluca Giavaresi, Aurelio Lorico, Riccardo Alessandro

College of Osteopathic Medicine (TUN) Publications and Research

The development of effective nanosystems for drug delivery represents a key challenge for the improvement of most current anticancer therapies. Recent progress in the understanding of structure and function of extracellular vesicles (EVs)-specialized membrane-bound nanocarriers for intercellular communication-suggests that they might also serve as optimal delivery systems of therapeutics. In addition to carrying proteins, lipids, DNA and different forms of RNAs, EVs can be engineered to deliver specific bioactive molecules to target cells. Exploitation of their molecular composition and physical properties, together with improvement in bio-techniques to modify their content are critical issues to target them to specific cells/tissues/organs. Here, …

Power Output In Rugby Players Comparing Unilateral And Bilateral Isotonic Upper-Body Resistance Exercise, Evan Nakachi, James D. George, Allen Parcell, Dennis Eggett, Brent Feland

International Journal of Exercise Science

International Journal of Exercise Science 12(6): 691-700, 2019. Bilateral deficit (BLD) occurs when the internal muscular force generated during simultaneous bilateral limb exercise is lower than the sum of internal muscular forces generated during separate right limb and left limb unilateral exercise, while attempting to oppose the same total external load. Numerous BLD studies have evaluated force output differences during exercise; however, no study has determined whether BLD exists when generating power during isotonic upper-body exercise. To address this, we measured and compared power output across unilateral and bilateral isotonic upper-body exercise. Seventeen college male rugby players (age = 21.8 …

Lumen Apposing Metal Stents In Drainage Of Pancreatic Walled-Off Necrosis, Are They Any Better Than Plastic Stents? A Systematic Review And Meta-Analysis Of Studies Published Since The Revised Atlanta Classification Of Pancreatic Fluid Collections, Babu P. Mohan, Mahendran Jayaraj, Ravishankar Asokkumar, Mohammed Shakhatreh, Parul Pahal, Suresh Ponnada, Udayakumar Navaneethan, Douglas G. Adler

School of Medicine Faculty Research

Lumen-apposing metal stents (LAMS) are increasingly being used in the drainage of pancreatic walled-off necrosis (WON). Best choice of stent is subject to argument, and studies are varied in the reported outcomes between LAMS and plastic stents (PS) to this end. We conducted a comprehensive search of multiple electronic databases and conference proceedings including PubMed, EMBASE, and Web of Science databases (earliest inception through July 2018) to identify studies that reported on the use of LAMS and PS in WON drainage. Studies published since the release of the revised Atlanta classification for pancreatic fluid collections (2014 to current) were included …

Rediscovering The Axolotl As A Model For Thyroid Hormone Dependent Development, Anne Crowner, Shivam Khatri, Dana Blichmann, S. Randal Voss

Neuroscience Faculty Publications

The Mexican axolotl (Ambystoma mexicanum) is an important model organism in biomedical research. Much current attention is focused on the axolotl's amazing ability to regenerate tissues and whole organs after injury. However, not forgotten is the axolotl's equally amazing ability to thwart aspects of tissue maturation and retain juvenile morphology into the adult phase of life. Unlike close tiger salamander relatives that undergo a thyroid hormone regulated metamorphosis, the axolotl does not typically undergo a metamorphosis. Instead, the axolotl exhibits a paedomorphic mode of development that enables a completely aquatic life cycle. The evolution of paedomorphosis allowed axolotls …

Comparison Of The Effects Of Linear And Non-Linear Resistance Training Periodization On Morphofunctional Capacity Of Subjects With Different Fitness Levels: A Systematic Review, Rafael M. Pitta, Carla G. S. Pinto Montenegro, Roberta L. Rica, Danilo Sales Bocalini, Ramires A. Tibana, Jonato Prestes, Whitley J. Stone, Aylton J. Figueira Jr.

International Journal of Exercise Science

International Journal of Exercise Science 12(4): 666-690, 2019. Resistance training (RT) is recognized as an efficient method to improve muscle strength, power, hypertrophy; all are fundamental components of functional health and quality of life. Variables of RT such as volume, intensity, density, rest interval, duration, exercise order and selection, training frequency, and periodization models (i.e. linear periodization (LP), reverse linear periodization (RLP), block periodization (BP), and nonlinear periodization (NLP): undulating periodization (UP) and weekly undulating periodization (WUP)) are manipulated to potentiate musculoskeletal adaptations. The aim of the present study was to conduct a systematic review of studies comparing different periodization …

The Effect Of Exercise Order In Circuit Training On Muscular Strength And Functional Fitness In Older Women, Diogo Correia Cardozo, Belmiro Freitas De Salles, Pietro Mannarino, Ana Paula Sena Vasconcelos, Humberto Miranda, Jeffrey M. Willardson, Roberto Simão

International Journal of Exercise Science

International Journal of Exercise Science 12(4): 657-665, 2019.The purpose of this study was to analyze the effect of different orders of exercises in circuit training on strength and functional fitness in older women over a 12-week period. After 10 repetition maximum (10-RM) and functional fitness baseline testing, thirty older women were randomly assigned into two groups. The exercise order for Group 1 was leg press, wide-grip lat pulldown, knee extension, pec deck fly, plantar flexion and triceps extension; Group 2 performed the same exercises, but in the opposite order: triceps extension, plantar flexion, pec deck fly, knee extension, wide-grip …

Trunk Muscle Activation During Dynamic Sling Training Exercises, Tobias Morat, Denis Holzer, Rieke Trumpf

International Journal of Exercise Science

International Journal of Exercise Science 12(1): 590-601, 2019. The purpose of this study was to examine the level of trunk muscle activation to characterize different dynamic sling training exercises. Thirty-six young adults (25±3 years, 1.78±0.1 m, 71.5±10.4 kg) performed six different sling training exercises while muscle activation of eight different trunk muscles was measured unilaterally by surface electrodes. Four of the exercises were conducted at two different difficulty levels (an easy and a hard version) by changing the body angle. The six sling training exercises differed regarding muscle activation, with significant differences (p< 0.05) between the three body parts (front, side, back). High muscle activations (76-87%) of the (front) trunk flexor muscles were measured. The back muscles tested reached more than half of their peak reference trial values only during one exercise tested. Regarding the side muscles, three of the sling exercises achieved muscle activations of 60% and higher (66-92%). All eight trunk muscles tested demonstrated a significantly (p< 0.05) higher muscle activation in the harder version compared with the easy version. Based on the results, the sling training exercises tested in this study seem to be most effective for the abdominal muscles. As assumed based on the former literature, changing the body angle during sling training exercises is shown to be a feasible way of adjusting the intensity of sling training. This could potentially be used in longitudinal sling training studies to assure a controlled, progressively increasing training intervention.