Antarctic Glacier Melting Modeling Distribution Of Bacterial Community Structure, 2024 Institute of Biology Bucharest of the Romanian Academy, Bucharest, Romania
Antarctic Glacier Melting Modeling Distribution Of Bacterial Community Structure, Corina Itcus, Constantin Marin, Soon Gyu Hong, Manuela Elisabeta Sidoroff, Cristian Coman, Cristina Purcarea
FRONTIERS UNBOUND: Exploring Extreme Environments
No abstract provided.
Molecular Detection Of Mycoplasma Spp. And Its Associated Risk Factors In Domestic Cats In The City Of Ibagué, Tolima, 2024 University of Tolima
Molecular Detection Of Mycoplasma Spp. And Its Associated Risk Factors In Domestic Cats In The City Of Ibagué, Tolima, Karen D. Osorio Muñoz Dr., Iang S. Rondon Barragan Prof.
The Thai Journal of Veterinary Medicine
Feline hemoplasmosis is a disease with worldwide distribution, mainly in tropical countries, where its transmission is favored by the presence of vectors such as fleas and ticks. In Colombia, the diagnosis of the disease in small animals has been limited to the identification of the pathogen in blood smears, which have low sensitivity and specificity, demanding methods of higher diagnostic value, such as those based on molecular techniques. The objective of the present study was to investigate the prevalence of Mycoplasma spp. in felines from the city of Ibagué using the PCR and the associated risk factors. Briefly, blood samples …
The Roles Of Cd4+ T Cell Help, Sex, And Dose In The Induction Of Protective Cd8+ T Cells Against A Lethal Poxvirus By Mrna-Lnp Vaccines, 2024 Thomas Jefferson University
The Roles Of Cd4+ T Cell Help, Sex, And Dose In The Induction Of Protective Cd8+ T Cells Against A Lethal Poxvirus By Mrna-Lnp Vaccines, Samita Kafle, Brian Montoya, Lingjuan Tang, Ying Tam, Hiromi Muramatsu, Norbert Pardi, Luis Sigal
Department of Microbiology and Immunology Faculty Papers
The role of CD4+ T cells in the induction of protective CD8+ T cells by mRNA lipid nanoparticle (LNP) vaccines is unknown. We used B6 or Tlr9−/− mice depleted or not of CD4+ T cells and LNP vaccines loaded with mRNAs encoding the ectromelia virus (ECTV) MHC class I H-2 Kb-restricted immunodominant CD8+ T cell epitope TSYKFESV (TSYKFESV mRNA-LNPs) or the ECTV EVM158 protein, which contains TSYKFESV (EVM-158 mRNA-LNPs). Following prime and boost with 10 μg of either vaccine, Kb-TSYKFESV-specific CD8+ T cells fully protected male and female mice from …
Cognition And Inflammation In Youth With Perinatal Hiv, 2024 UMSL
Cognition And Inflammation In Youth With Perinatal Hiv, Megan Niehaus, Julie Mannarino, Jacob Bolzenius, Tori Frerichs, Robert Paul
Undergraduate Research Symposium
Background: Perinatally acquired HIV (PHIV) remains a major global health challenge. Approximately 90% of the global population of PHIV reside in low- or middle-income countries (LMICs) where access to antiretroviral therapy (ART) remains incomplete, particularly for PHIV. With PHIV, the brain is exposed to the virus during critical periods of brain development without the immunological benefits from ART. Unlike adults with horizontally acquired HIV whose nadir CD4+ Tcell count is a strong correlate of cognitive difficulties that persist after sustained use of ART, cognitive symptoms among PHIV youth are independent of traditional HIV disease metrics. Prior studies indicate that PHIV …
Leaf Diseases And Their Management In Oats, 2024 Department of Primary Industries and Regional Development, Western Australia
Leaf Diseases And Their Management In Oats, Department Of Primary Industries And Regional Development, Western Australia
Biosecurity factsheets
Leaf diseases of oats impact on grain yield and quality and reduce hay quality characteristics, such as colour and digestibility. This page outlines the symptoms, factors favouring disease risk and spread, and management.
Major leaf diseases of oats are septoria avenae blotch, stem rust, leaf rust, and barley yellow dwarf virus. Their severity changes with seasons.
Wheat Streak Mosaic Virus And Wheat Curl Mite And Their Management, 2024 Department of Primary Industries and Regional Development, Western Australia
Wheat Streak Mosaic Virus And Wheat Curl Mite And Their Management, Department Of Primary Industries And Regional Development, Western Australia
Biosecurity factsheets
Wheat streak mosaic virus (WSMV) is a seed and mite-borne virus that infects wheat, causing severe leaf symptoms and reduced yields. The symptoms and damage are more severe in wheat than other hosts, in which infection is symptomless.
Wheat streak mosaic virus can cause crop failure when widespread infection occurs in seedling wheat, particularly when a heavily WSMV-infected green bridge is not controlled before sowing an early crop, and warm temperatures favour mites.
Wheat curl mite (Aceria tosichella) is the only known vector of WSMV. It can transmit the virus in its nymph and adult stages.
Bean Yellow Mosaic Virus And Its Management In Lupins, 2024 Department of Primary Industries and Regional Development, Western Australia
Bean Yellow Mosaic Virus And Its Management In Lupins, Department Of Primary Industries And Regional Development, Western Australia
Biosecurity factsheets
Bean yellow mosaic virus (BYMV) is an aphid-transmitted virus that commonly causes necrotic symptoms that kills lupin plants when infected early before pod set. When plants are infected after pod set, black pods develop (known as black pod syndrome).
BYMV is found predominantly in high rainfall areas of the Western Australian (WA) grainbelt. This page outlines the symptoms, diagnosis, factors favouring disease risk and spread, yield and quality impacts, and management for BYMV in lupin crops in WA
Antibiotic-Resistant Gram-Negative Bacteria In A Local Wastewater Treatment Plant In North Georgia, 2024 University of North Georgia
Antibiotic-Resistant Gram-Negative Bacteria In A Local Wastewater Treatment Plant In North Georgia, Nou Moua, Lindsay Mccuen, Sarah White, Swapna Bhat, Margi Flood, Jeanelle Morgan
Georgia Journal of Science
Antibiotics are some of the most essential lifesaving drugs currently available to us against infectious diseases. Several pathogens are developing resistance to these drugs and many have become resistant to multiple antibiotics. Such multi-drug resistance is becoming a global issue and has been found in many environments including wastewater treatment plants (WWTPs). In this study, we sampled a local WWTP for antibiotic-resistant bacteria. This WWTP is in North Georgia and runs directly into Lake Lanier, which is the main source of drinking water for the Atlanta area as well as a popular spot for water recreation. We obtained treated and …
Avicennia Marina Mangrove Plant Mediated Selenium Nanoparticles And Their Therapeutic Activity Against Oral Pathogens And Other Biological Properties, 2024 Marine Microbial Research Lab, Department of Research and Analytics (DORA), Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai, India; Centre for Marine and Aquatic Research (CMAR), Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai, India
Avicennia Marina Mangrove Plant Mediated Selenium Nanoparticles And Their Therapeutic Activity Against Oral Pathogens And Other Biological Properties, Kannan Kamala, Pitchiah Sivaperumal, Dhanraj Ganapathy
Journal of Dentistry Indonesia
In the last few decades nanoparticles are widely used in the control of many pathogenic bacteria, fungi, viruses, and cancer growth both in-vitro and in-vivo. A marine plant of Avicennia marina is widely used in traditional medicine for diabetes, inflammation and skin diseases. Objective: In general Avicennia marina has been used as a traditional medicine to treat various diseases and it has shown significant inhibition against various pathogen and the formation of free radicals. Also, the plant A.marina mediated selenium nanoparticles has therapeutic activity has promising to develop biocompatible new cost effective treatment for various oral diseases. Methods: …
Probiotic Properties, Antioxidant Potential, Bile Salts Tolerance And Antibiotic Susceptibility Assessment Of Streptococcus Thermophilus Isolates, 2024 Laboratory of Improvement of Agricultural Production, Biotechnology and Environment, Department of Biology, Faculty of Sciences, Université Mohamed Premier, Oujda 60000, Morocco. & Process Engineering and Food Technologies Department, Institute of Agronomy and Veterinary medicine (IAV-Hassan II) BP 6202 Rabat, Morocco
Probiotic Properties, Antioxidant Potential, Bile Salts Tolerance And Antibiotic Susceptibility Assessment Of Streptococcus Thermophilus Isolates, Nora Hamdaoui, Ali Azghar, Chaymae Benkirane, Haytham Bouaamali, Mouncif Mohamed, Douaae Ou-Yahia, Bouchra El Guerrouj, Abdeslam Asehraou, Adil Maleb, Belkheir Hammouti, Raed Alkowni, Shehdeh Jodeh, Meziane Mustapha
Palestinian Medical and Pharmaceutical Journal
Streptococcus thermophilus was considered one of the probiotic bacterial strains found in milk, cheese, and yogurt that provided health benefits to humans. Due to their probiotic potential, S. thermophilus can be very helpful in replacing chemical preservatives. This study came out to investigate the probiotic activity of different ten S. thermophilus isolates obtained from raw cow milk in eastern Morocco. The antimicrobial tests against multidrug-resistant bacteria (MDR): Staphylococcus aureus, and Escherichia coli were evaluated using the disc diffusion technique. In addition, the antioxidant potential was tested using the DPPH free radical assay. The bile salt tolerance was evaluated using …
Phytochemicals And Medicinal Plants: A Promising Frontier For Antiviral Research In The Age Of Pandemics: Review, 2024 Department of Pharmaceutics, Dr. D.Y. Patil Institute of Pharmaceutical Sciences and Research, Pimpri, Pune, Maharashtra, India- 411018.
Phytochemicals And Medicinal Plants: A Promising Frontier For Antiviral Research In The Age Of Pandemics: Review, Diksha Tapsale, Radhika Baheti, Jayashri Mahore, Rashmi Trivedi, Vinita Patole
Palestinian Medical and Pharmaceutical Journal
The recent outbreaks of viral infections have underscored the urgent need for effective antiviral agents. While synthetic antivirals are frequently employed, they may have limited efficacy and cause negative side effects due to their synthetic nature. An alternative approach that holds promise is phytotherapy, which employs medicinal plants and their secondary metabolites to treat various infections. Herbal remedies offer several advantages, such as lower toxicity and increased efficacy in some viral outbreaks. As extraction technology and customized delivery systems continue to advance, herbal-based therapies are gaining greater popularity. The current review article summarizes the various phytoconstituents isolated from medicinal plants …
Using Origami And Shrinky Dinks To Create Active Learning Activities To Tackle Two Microbiology Concepts: Cell Structure Differences And Operon Regulation, 2024 Thomas Jefferson University
Using Origami And Shrinky Dinks To Create Active Learning Activities To Tackle Two Microbiology Concepts: Cell Structure Differences And Operon Regulation, Manuela Tripepi, Hannah M. Schapiro
College of Life Sciences Faculty Papers
This paper presents two low-cost hands-on activities designed to enhance student understanding and address the pedagogical challenges faced by microbiology professors in teaching concepts related to cell structure and gene regulation. In the first activity, we used Shrinky Dinks and Jeopardy-style game questions to explore the differences between prokaryotic and eukaryotic cells. Students have to collect pieces and physically build their cell models. The second activity uses origami organelles sets from Edvotek to illustrate the regulation of gene expression in the lac and trp operons, incorporating mutation scenarios for analysis. The intended audience comprises undergraduate students in microbiology, including biology, …
Multidrug-Resistant Esbl-Producing Escherichia Coli Coexisting With Colistin-Resistance Genes In Pig Farms, Central Thailand, 2024 Chulalongkorn University, College of Public Health Science
Multidrug-Resistant Esbl-Producing Escherichia Coli Coexisting With Colistin-Resistance Genes In Pig Farms, Central Thailand, Wipawee Songsaeng, Nutthee Am-In, Nuvee Prapasarakul, Wandee Sirichokchatchawan
The Thai Journal of Veterinary Medicine
The presence of extended-spectrum beta-lactamase and colistin resistance E. coli in food-producing animals is a public health concern. This study was conducted using a rigorous methodology to survey the prevalence of ESBL-producing and colistin-resistant E. coli from pig farms in the central part of Thailand. A total of 519 samples were collected from fecal, feed, and waste in 53 farms located in central Thailand. All samples were inoculated onto selective agar, and species identification was performed using biochemical assays and MAlDI-TOF MS. Antimicrobial susceptibility was determined by broth microdilution, and ESBL production was confirmed by the combination disc diffusion method. …
Development Of A Urothelial Cell Line Expressing A Caspase-1 Biosensor To Measure Cellular Inflammatory Responses To Potential Uropathogens, 2024 Loyola University of Chicago Graduate School
Development Of A Urothelial Cell Line Expressing A Caspase-1 Biosensor To Measure Cellular Inflammatory Responses To Potential Uropathogens, Nikita Riya Kesav
Master's Theses
Urinary tract infections are one of the most common bacterial infections, historically implicating Escherichia coli as the causative pathogen. However, it is now known that there are a variety of bacteria that exist within the urinary tract, acting as either beneficial uroprotectives or opportunistic uropathogens. Furthermore, there are significant gaps in our understanding as to how these bacteria interact with the urothelium and what role each plays in maintaining or disrupting homeostasis. Research has shown that Toll-like receptor 4 (TLR4) signaling and Nod-like Receptor Protein 3 play a role in inflammasome activation during infection, triggering caspase-1 activation and inducing release …
Elucidating Enterococcal Mechanisms Underlying Recurrent Urinary Tract Infections, 2024 Loyola University of Chicago Graduate School
Elucidating Enterococcal Mechanisms Underlying Recurrent Urinary Tract Infections, Baylie Hochstedler-Kramer
Dissertations
Urinary tract infection (UTI) is one of the most common bacterial infections globally and can lead to life-threatening complications. UTI disproportionately affects females, with the majority of females being treated for at least one UTI in their lifetime. Of the females who develop UTI in their lifetime, almost one third will develop recurrence within six months after initial treatment and many will struggle with UTI recurrence for long spans of their lives. Although recurrent UTI has previously been attributed to persistence of Escherichia coli, recent studies utilizing more sensitive detection methods have shown Enterococcus faecalis is strongly associated with recurrent …
Time-Transgressive Microbial Diversity In A Tropical Bat Guano Accumulation, Deer Cave, Mulu, Borneo, 2024 Carleton University, Canada
Time-Transgressive Microbial Diversity In A Tropical Bat Guano Accumulation, Deer Cave, Mulu, Borneo, Joyce Lundberg, Donald A. Mcfarlane
International Journal of Speleology
Bat guano accumulations in caves can constitute large deposits of organic material, particularly chitin and its degradation products, that host a diverse microbiome. Previous microbiological studies have not addressed the stratified nature of these deposits in the context of the timeframe of the decomposition process. We present such data (temperature, pH, DNA sampling of eight carbon-dated strata) for a 75 cm-deep tropical guano accumulation that undergoes complete decomposition over a timescale of ~120 years. The aerobic, surface layer of freshly-fallen guano has the greatest diversity of taxa, with Bacteroidota co-dominant with Pseudomonadota, and includes many taxa unique to this …
The Antioxidants And Anti-Inflammatories Benefit Of Broccoli Sprout Diets And Their Relation To Health, 2024 University of Maine
The Antioxidants And Anti-Inflammatories Benefit Of Broccoli Sprout Diets And Their Relation To Health, Tolu Esther Alaba
Electronic Theses and Dissertations
Inflammatory bowel disease is a chronic intestinal condition characterized by severe inflammation, oxidative stress, microbial dysbiosis, and cellular structure and barrier damage. The complex mechanism of pathologies makes it challenging to manage the disease effectively. Most current treatments target only inflammation using steroids and antibiotics with side effects. Therefore, recent research has focused on safe and effective nutritional options. Broccoli sprouts, Brassica oleracea variety italica, is a member of the Brassicaceae family and has documented antioxidant, anti-inflammatory, and gut protective benefits against inflammatory bowel diseases. These benefits have been associated mainly with sulforaphane from dietary glucosinolates present in broccoli sprouts. …
The Experience Of Homelessness And Its Effects On Gut Eubiosis, 2024 Portland State University
The Experience Of Homelessness And Its Effects On Gut Eubiosis, Kamerin Villagomez
University Honors Theses
Microorganisms which populate the human gastrointestinal tract (GIT) have a profound effect on overall human health. The relationship between host health and eubiosis, or balance, of the GIT microbiome is symbiotic and can have reciprocal relationships with quality of sleep, quality of diet, stress and mental health, and the experience of pain. These specific aspects of health are unique in populations experiencing homelessness due to the multi-dimensional and complex nature of their lived experience. Very few studies explore populations experiencing homelessness, with even fewer investigating the intersection between this population and the human GIT microbiome. It is important to do …
Investigation Of Calcium And Calmodulin Signaling During Jc Polyomavirus Infection, 2024 The University of Maine
Investigation Of Calcium And Calmodulin Signaling During Jc Polyomavirus Infection, Avery Bond
Electronic Theses and Dissertations
JC polyomavirus (JCPyV) infects 50-80% of the human population. In healthy individuals, JCPyV establishes a persistent, asymptomatic infection in the kidneys. In severely immunocompromised individuals, JCPyV infection can result in a fatal brain infection called progressive multifocal leukoencephalopathy (PML). PML causes a lytic infection of myelin-producing glial cells in the brain and becomes progressively debilitating, sometimes resulting in death within one year of symptom onset. There are currently no targeted, approved treatments for PML, underscoring the importance of continued research on JCPyV and PML.
To identify potential antiviral therapeutics, the Maginnis laboratory performed a large-scale drug screen using the National …
The Molecular Detection Of Hemotropic Mycoplasma Species In Dogs, 2024 Department of Microbiology, Faculty of Veterinary Medicine, Aydin Adnan Menderes University
The Molecular Detection Of Hemotropic Mycoplasma Species In Dogs, Hafize Tuğba Yüksel Dolgun, Şükrü Kirkan
The Thai Journal of Veterinary Medicine
Hemotropic mycoplasmas are uncultured bacteria that cause different degrees of hemolytic anemia in infected hosts. Molecular approaches are used to diagnose hemotropic mycoplasmas since they are difficult to identify using conventional methods. The aim of this study was to use molecular approaches to determine hemotropic mycoplasmas in dogs. Blood samples were collected in tubes (with EDTA) from 100 dogs. After DNA extraction, 100 DNA samples were investigated by PCR. Hemotropic mycoplasma was detected in 12 (12%) samples and positive samples were subjected to Sanger sequencing. Mycoplasma haemocanis was detected in 6 (50.0%) of the samples, Candidatus Mycoplasma hematoparvum in 5 …