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Articles 181 - 193 of 193
Full-Text Articles in Pharmacy and Pharmaceutical Sciences
Method Of Administering Narcotic Antagonists And Analgesics And Novel Dosage Forms Containing Same, Anwar A. Hussain
Method Of Administering Narcotic Antagonists And Analgesics And Novel Dosage Forms Containing Same, Anwar A. Hussain
Pharmaceutical Sciences Faculty Patents
The invention provides a novel method of administering narcotic antagonists, narcotic analgesics and related compounds, and novel dosage forms containing those compounds which are adapted for nasal administration. The nasal dosage forms disclosed include solutions, suspensions, gels and ointments. Especially preferred compounds which can be advantageously administered in accordance with the invention include naloxone, naltrexone, nalbuphine, levorphanol, buprenorphine, butorphanol, Δ9-tetrahydrocannabinol (THC), cannabidiol (CBD) and levonantradol.
Alteration Of Gallium Biodistribution Using Indium Complexes For Enhanced Early Imaging, John W. Triplett
Alteration Of Gallium Biodistribution Using Indium Complexes For Enhanced Early Imaging, John W. Triplett
Pharmaceutical Sciences Faculty Patents
Radiopharmaceutical compositions and methods for tumor tomography in mammals are disclosed, wherein radioactive gallium and non-radioactive indium are injected into said mammals whereby the affinity of said radioactive gallium for non-tumor tissues is decreased, resulting in enhanced imaging characteristics.
Novel Method Of Administering Β-Blockers And Novel Dosage Forms Containing Same, Anwar A. Hussain
Novel Method Of Administering Β-Blockers And Novel Dosage Forms Containing Same, Anwar A. Hussain
Pharmaceutical Sciences Faculty Patents
The invention provides a novel method of administering selected known adrenergic β-receptor blocking agents, such as dichloroisoproterenol, pronethalol, sotalol and alprenolol, which are of use in the treatment of angina pectoris, arrhythmias, hypertension and other cardiac conditions, and migraine. The invention further provides novel dosage forms of those β-blockers which are adapted for nasal administration and which include solutions, suspensions, gels and ointments.
Nasal Dosage Forms Of Propranol, Anwar A. Hussain, Shinichiro Hirai, Rima Bawarshi
Nasal Dosage Forms Of Propranol, Anwar A. Hussain, Shinichiro Hirai, Rima Bawarshi
Pharmaceutical Sciences Faculty Patents
The invention relates to a novel method of administering propranolol, a known β-adrenergic blocking agent widely used in the treatment of angina pectoris, arrhythmias, hypertension and other cardiac conditions, and migraine. The invention further relates to novel dosage forms of propranolol which are adapted for nasal administration and which include solutions, suspensions, gels and ointments.
Nasal Dosage Forms Containing Natural Female Sex Horomones, Anwar A. Hussain, Shinichiro Hirai, Rima Bawarshi
Nasal Dosage Forms Containing Natural Female Sex Horomones, Anwar A. Hussain, Shinichiro Hirai, Rima Bawarshi
Pharmaceutical Sciences Faculty Patents
The invention relates to a novel method of administering the natural female sex hormones, 17 β-estradiol and progesterone, to achieve enhanced bioavailability thereof. The invention further relates to novel dosage forms of 17 β-estradiol and/or progesterone which are adapted for nasal administration, such as solutions, suspensions, gels and ointments. The dosage forms containing a combination of 17 β-estradiol and progesterone are particularly useful as contraceptives, while the dosage forms containing only one of the hormonal components find utility in the treatment of conditions such as menopause, menstrual disorders, etc., which are known to respond to administration of a natural or …
Method Of Administering Natural Female Sex Horomones, Anwar A. Hussain, Shinichiro Hirai, Rima Bawarshi
Method Of Administering Natural Female Sex Horomones, Anwar A. Hussain, Shinichiro Hirai, Rima Bawarshi
Pharmaceutical Sciences Faculty Patents
The invention relates to a novel method of administering the natural female sex hormones, 17 β- estradiol and progesterone, to achieve enhanced bioavailability thereof. The invention further relates to novel dosage forms of 17 β- estradiol and/or progesterone which are adapted for nasal administration, such as solutions, suspensions, gels and ointments. The dosage forms containing a combination of 17 β-estradiol and progesterone are particularly useful as contraceptives, while the dosage forms containing only one of the hormonal components find utility in the treatment of conditions such as menopause, menstrual disorders, etc., which are known to respond to administration of a …
Nasal Administration Of Propranolol, Anwar A. Hussain, Shinichiro Hirai, Rima Bawarshi
Nasal Administration Of Propranolol, Anwar A. Hussain, Shinichiro Hirai, Rima Bawarshi
Pharmaceutical Sciences Faculty Patents
The invention relates to a novel method of administering propranolol, a known β-andrenergic blocking agent widely used in the treatment of angina pectoris, arrhythmias, hypertension and other cardiac conditions, and migraine. The invention further relates to novel dosage forms of propranolol which are adapted for nasal administration and which include solutions, suspensions, gels and ointments.
Testing The Integrity Of Liquid Containing Hermetically Sealed Containers By The Use Of Radioactive Markers, Patrick P. Deluca, L. David Butler
Testing The Integrity Of Liquid Containing Hermetically Sealed Containers By The Use Of Radioactive Markers, Patrick P. Deluca, L. David Butler
Pharmaceutical Sciences Faculty Patents
A method for detecting leaky ampules filled with a liquid such as a parenteral solution. The ampules to be tested are immersed in a solution containing a short-lived radionuclide, and a pressure differential is imposed between the solution containing the radionuclide and the parenteral solution or other liquid contained in the ampules. The ampules are then removed from solution, decontaminated to remove any solution adhering to the outer surface and pores thereof, dried, and finally examined for electromagnetic radiation, preferably gamma radiation, emanating from the interior of the ampules which would indicate a leaky condition thereof.
Synthesis And Use Of Diagnostic Radio-Pharmaceuticals Comprising Radioactive Isotopes Of Bromine With Dyes, John W. Triplett, Randall B. Smith
Synthesis And Use Of Diagnostic Radio-Pharmaceuticals Comprising Radioactive Isotopes Of Bromine With Dyes, John W. Triplett, Randall B. Smith
Pharmaceutical Sciences Faculty Patents
A process for preparing bromine-containing dyes labelled with gamma-emitting isotopes of bromine, and the product thereof which is useful as an imaging agent for the hepato-biliary system, particularly in dynamic imaging methods. The dyes prepared are from the class of triarylmethane dyes, and also from the phthalein subclass of the class of xanthene dyes, and the labelling thereof is effected with 76Br, 77 Br or 82 Br. The process for preparing these dyes involves reacting the non-brominated dye precursor with either 76 Br2, 77 Br2 or 82 Br2. This is a substitution type of …
Derivative Of Aspirin, Anwar A. Hussain, James E. Truelove, Harry B. Kostenbauder
Derivative Of Aspirin, Anwar A. Hussain, James E. Truelove, Harry B. Kostenbauder
Pharmaceutical Sciences Faculty Patents
There is provided a novel derivative of 2-acetoxybenzoic acid, i.e., 1-O-(2'-acetoxy)benzoyl-α-D-2-deoxyglucopyranose, which is suitable for the attainment of high 2-acetoxybenzoic acid blood levels without irritation of the gastrointestinal lining.
Derivatives Of Aspirin, Anwar A. Hussain, James E. Truelove, Harry B. Kostenbauder
Derivatives Of Aspirin, Anwar A. Hussain, James E. Truelove, Harry B. Kostenbauder
Pharmaceutical Sciences Faculty Patents
There are provided novel derivatives of 2-acetoxybenzoic acid, which are substituted 1-0-(2'acetoxy)benzoyl-α-D-2-deoxyglucopyranose derivatives and are suitable for the attainment of high 2-acetoxybenzoic acid blood levels without irritation of the gastrointestinal lining.
Tobacco Smoke Filter Material, George A. Digenis, Manvendra B. Shambhu
Tobacco Smoke Filter Material, George A. Digenis, Manvendra B. Shambhu
Pharmaceutical Sciences Faculty Patents
A tobacco smoke filter comprising a imidazole-containing polymer, the imidazole groups being chemically bound to said polymer.
Radiodiagnostic Agent, George A. Digenis, Manvendra B. Shambhu, Michael C. Theodorakis
Radiodiagnostic Agent, George A. Digenis, Manvendra B. Shambhu, Michael C. Theodorakis
Pharmaceutical Sciences Faculty Patents
A radiodiagnostic agent comprising a solid, insoluble nontoxic synthetic resin, such as polystyrene, bearing a detectable amount of technetium 99m thereon. This agent is useful for analyzing the gastrointestinal tract, for example, for gastric emptying time, by means of a gamma camera.