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Pharmaceutical Sciences Faculty Patents

Dosage

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Full-Text Articles in Pharmacy and Pharmaceutical Sciences

Novel Method Of Administering Aspirin And Dosage Forms Containing Same, Anwar A. Hussain, Lewis W. Dittert, Thomas S. Foster Dec 1989

Novel Method Of Administering Aspirin And Dosage Forms Containing Same, Anwar A. Hussain, Lewis W. Dittert, Thomas S. Foster

Pharmaceutical Sciences Faculty Patents

The invention relates to a novel method of administering aspirin to achieve improved delivery thereof. The invention further relates to novel dosage forms of neutralized aspirin adapted for nasal administration, such as solutions, suspensions, gels and ointments. These dosage forms find utility in the treatment of conditions known to respond to the administration of aspirin, particularly in the treatment of migraine and in the mitigation of cardiovascular damage resulting from heart attack.


Method Of Administering Narcotic Antagonists And Analgesics And Novel Dosage Forms Containing Same, Anwar A. Hussain Aug 1984

Method Of Administering Narcotic Antagonists And Analgesics And Novel Dosage Forms Containing Same, Anwar A. Hussain

Pharmaceutical Sciences Faculty Patents

The invention provides a novel method of administering narcotic antagonists, narcotic analgesics and related compounds, and novel dosage forms containing those compounds which are adapted for nasal administration. The nasal dosage forms disclosed include solutions, suspensions, gels and ointments. Especially preferred compounds which can be advantageously administered in accordance with the invention include naloxone, naltrexone, nalbuphine, levorphanol, buprenorphine, butorphanol, Δ9-tetrahydrocannabinol (THC), cannabidiol (CBD) and levonantradol.


Novel Method Of Administering Β-Blockers And Novel Dosage Forms Containing Same, Anwar A. Hussain Jan 1984

Novel Method Of Administering Β-Blockers And Novel Dosage Forms Containing Same, Anwar A. Hussain

Pharmaceutical Sciences Faculty Patents

The invention provides a novel method of administering selected known adrenergic β-receptor blocking agents, such as dichloroisoproterenol, pronethalol, sotalol and alprenolol, which are of use in the treatment of angina pectoris, arrhythmias, hypertension and other cardiac conditions, and migraine. The invention further provides novel dosage forms of those β-blockers which are adapted for nasal administration and which include solutions, suspensions, gels and ointments.


Nasal Dosage Forms Of Propranol, Anwar A. Hussain, Shinichiro Hirai, Rima Bawarshi Jul 1983

Nasal Dosage Forms Of Propranol, Anwar A. Hussain, Shinichiro Hirai, Rima Bawarshi

Pharmaceutical Sciences Faculty Patents

The invention relates to a novel method of administering propranolol, a known β-adrenergic blocking agent widely used in the treatment of angina pectoris, arrhythmias, hypertension and other cardiac conditions, and migraine. The invention further relates to novel dosage forms of propranolol which are adapted for nasal administration and which include solutions, suspensions, gels and ointments.


Nasal Dosage Forms Containing Natural Female Sex Horomones, Anwar A. Hussain, Shinichiro Hirai, Rima Bawarshi May 1983

Nasal Dosage Forms Containing Natural Female Sex Horomones, Anwar A. Hussain, Shinichiro Hirai, Rima Bawarshi

Pharmaceutical Sciences Faculty Patents

The invention relates to a novel method of administering the natural female sex hormones, 17 β-estradiol and progesterone, to achieve enhanced bioavailability thereof. The invention further relates to novel dosage forms of 17 β-estradiol and/or progesterone which are adapted for nasal administration, such as solutions, suspensions, gels and ointments. The dosage forms containing a combination of 17 β-estradiol and progesterone are particularly useful as contraceptives, while the dosage forms containing only one of the hormonal components find utility in the treatment of conditions such as menopause, menstrual disorders, etc., which are known to respond to administration of a natural or …