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Articles 1 - 10 of 10
Full-Text Articles in Pharmacy and Pharmaceutical Sciences
Use Of Parthenolide Derivatives As Antileukemic And Cytotoxic Agents, Peter A. Crooks, Craig T. Jordan, Xiaochen Wei
Use Of Parthenolide Derivatives As Antileukemic And Cytotoxic Agents, Peter A. Crooks, Craig T. Jordan, Xiaochen Wei
Pharmaceutical Sciences Faculty Patents
To read this abstract, please download this patent.
Semi-Synthetic Mithramycin Derivatives With Anti-Cancer Activity, Jürgen Rohr, Daniel Scott, Markos Leggas, Jhong-Min Chen, Oleg V. Tsodikov
Semi-Synthetic Mithramycin Derivatives With Anti-Cancer Activity, Jürgen Rohr, Daniel Scott, Markos Leggas, Jhong-Min Chen, Oleg V. Tsodikov
Pharmaceutical Sciences Faculty Patents
Mithramycin derivatives and their pharmaceutically acceptable salts are disclosed. The mithramycin derivatives can be used in the treatment of Ewing sarcoma or other cancer or neuro-disease associated with an aberrant erythroblast transformation- specific transcription factor.
Use Of Parthenolide Derivatives As Antileukemic And Cytotoxic Agents, Peter A. Crooks, Craig T. Jordan, Xiaochen Wei
Use Of Parthenolide Derivatives As Antileukemic And Cytotoxic Agents, Peter A. Crooks, Craig T. Jordan, Xiaochen Wei
Pharmaceutical Sciences Faculty Patents
To read this abstract, please download this patent.
Derivatives Of Mithramycin And Methods Of Making And Uses Thereof, Jürgen Rohr, Lily L. Remsing, Mohammad Ner-E-Alam, Jose A. Salas, Carmen Mendez, Alfredo F. Brana, Ana M. Gonzalez
Derivatives Of Mithramycin And Methods Of Making And Uses Thereof, Jürgen Rohr, Lily L. Remsing, Mohammad Ner-E-Alam, Jose A. Salas, Carmen Mendez, Alfredo F. Brana, Ana M. Gonzalez
Pharmaceutical Sciences Faculty Patents
The invention, in one aspect, generally relates to mithramycin derivatives from mutated Streptomyces argillaceus and their production. The invention also relates using the derivatives for the treatment of various diseases. Finally, the invention relates to a mutated Streptomyces argillaceus useful in the production of the mithramycin derivatives.
Use Of Parthenolide Derivatives As Antileukemic And Cytotoxic Agents, Peter A. Crooks, Craig T. Jordan, Xiaochen Wei
Use Of Parthenolide Derivatives As Antileukemic And Cytotoxic Agents, Peter A. Crooks, Craig T. Jordan, Xiaochen Wei
Pharmaceutical Sciences Faculty Patents
Compounds of the formula having anti-tumor activity, wherein R1 and R2 are as described herein
Water Soluble Derivatives Of Camptothecin/Homocamptothecin, Thomas Burke, Ayhan Demir, Cihangir Tanyeli, Ashok J. Chavan, Tie-Lin Wang, Yves Pommier
Water Soluble Derivatives Of Camptothecin/Homocamptothecin, Thomas Burke, Ayhan Demir, Cihangir Tanyeli, Ashok J. Chavan, Tie-Lin Wang, Yves Pommier
Pharmaceutical Sciences Faculty Patents
Camptothecin and homocamptothecin analogs and derivatives are provided incorporating alkylamine and polyalkylamine moieties.
Iodo-Nonoxynol-9-Derivatives And Methods For Their Use, George Digenis, Philip Fowler, Kazuya Matsumoto, Gustavo Doncel
Iodo-Nonoxynol-9-Derivatives And Methods For Their Use, George Digenis, Philip Fowler, Kazuya Matsumoto, Gustavo Doncel
Pharmaceutical Sciences Faculty Patents
Mono- and di-iodinated nonoxynol-9-derivatives and methods for their use are disclosed.
Derivatives Of N-Chloro-N-Methyl Glucamine And N-Chloro-N-Methyl Glucamine Esters, Anwar A. Hussain, Bassam Tashtoush, Lewis W. Dittert
Derivatives Of N-Chloro-N-Methyl Glucamine And N-Chloro-N-Methyl Glucamine Esters, Anwar A. Hussain, Bassam Tashtoush, Lewis W. Dittert
Pharmaceutical Sciences Faculty Patents
The present invention relates to N-chloro-N-methyl glucamine and N-chloro-N-methyl glucamine esters, and their use as agents for water disinfection and as mild oxidizing agents for the radiolabeling of oxidation-sensitive biomolecules.
Derivative Of Aspirin, Anwar A. Hussain, James E. Truelove, Harry B. Kostenbauder
Derivative Of Aspirin, Anwar A. Hussain, James E. Truelove, Harry B. Kostenbauder
Pharmaceutical Sciences Faculty Patents
There is provided a novel derivative of 2-acetoxybenzoic acid, i.e., 1-O-(2'-acetoxy)benzoyl-α-D-2-deoxyglucopyranose, which is suitable for the attainment of high 2-acetoxybenzoic acid blood levels without irritation of the gastrointestinal lining.
Derivatives Of Aspirin, Anwar A. Hussain, James E. Truelove, Harry B. Kostenbauder
Derivatives Of Aspirin, Anwar A. Hussain, James E. Truelove, Harry B. Kostenbauder
Pharmaceutical Sciences Faculty Patents
There are provided novel derivatives of 2-acetoxybenzoic acid, which are substituted 1-0-(2'acetoxy)benzoyl-α-D-2-deoxyglucopyranose derivatives and are suitable for the attainment of high 2-acetoxybenzoic acid blood levels without irritation of the gastrointestinal lining.