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Full-Text Articles in Pharmacy and Pharmaceutical Sciences
Nicotinic Receptor Antagonists In The Treatment Of Neuropharmacological Disorders, Peter A. Crooks, Linda P. Dwoskin, Alain Ravard
Nicotinic Receptor Antagonists In The Treatment Of Neuropharmacological Disorders, Peter A. Crooks, Linda P. Dwoskin, Alain Ravard
Pharmaceutical Sciences Faculty Patents
Nicotine analogs that have nicotinic receptor antagonist properties. These compounds have been shown to competitively inhibit dopamine release induced by nicotine. The nicotine analog compounds are useful in the treatment of nicotine abuse, smoking cessation therapy, as an antidote for nicotine intoxication, treatment of cognitive disorders such as Alzheimer's disease and for the treatment of Parkinson's disease.
Multicompartment Hard Capsule With Control Release Properties, George Digenis, Dagmar Noskova
Multicompartment Hard Capsule With Control Release Properties, George Digenis, Dagmar Noskova
Pharmaceutical Sciences Faculty Patents
The present invention relates to a hard capsule made from a material such as gelatin, starch or a hydrophilic polymer. The capsule of the present invention is formulated into a delivery system which incorporates pharmacologically active components in three or more distinct compartments. When three compartments are utilized in the capsule, the outer compartment incorporates a drug and excipients into a layer which coats the outer part of the capsule. This layer represents the rapid release portion of the delivery system. The intermediate compartment comprises a powder formulation comprised of a drug and excipients which represents the intermediary speed release …
Aminoalkylpyridine Compounds Which Are Useful As Anticonvulsant Drugs, Excitatory Amino Acid Inhibitors And Nmda Sigma Receptor Antagonists, Pankaja K. Kadaba
Aminoalkylpyridine Compounds Which Are Useful As Anticonvulsant Drugs, Excitatory Amino Acid Inhibitors And Nmda Sigma Receptor Antagonists, Pankaja K. Kadaba
Pharmaceutical Sciences Faculty Patents
Pharmaceutical compositions comprise as the active ingredient potent orally active, nonneurotoxic anticonvulsant compounds that are excitatory amino acid and NMDA/sigma receptor antagonists . . .
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