Physiology Commons^™

Cerebral Vasomotor Reactivity: Impact Of Hyperventilation Induced Hypocapnia On Hypercapnia Induced Vasodilation, Kevin M. Christmas

International Journal of Exercise Science: Conference Proceedings

Cerebral vasomotor reactivity (CVMR; the relationship of cerebral blood flow responses to changes in arterial carbon dioxide (PCO2)) is used to assess cerebral vascular function. CVMR is generally assessed during either steady-state or transient breathe-by-breathe changes in PCO2. In the transient method, a brief period of hyperventilation hypocapnia is often followed by hypercapnic rebreathing to induce a wide range of change in PCO2 to assess the capacity of CVMR. Assessment of CVMR during transient changes in PCO2 has been reported to be about 30% lower than that under steady-state conditions. One possibility for this discrepancy is that cerebral vasoconstriction during …

The Experience Of Weight Control, Exercise And Healthy Eating In Medically Triggered Patients, Elizabeth A. Espie, Mark Faries, Erik Gnagy

International Journal of Exercise Science: Conference Proceedings

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Effects Of Hot And Temperate Environments On Executive Function Tasks During Moderate And High Intensity Exercise, Stephen Decker, Heidi Bachrich, Nikki Kellman, La Tori Flowers, Eric J. Jones, Mark Faries

International Journal of Exercise Science: Conference Proceedings

Cognitive function testing during changes in body core temperature has been widely studied in regards to human performance, often employing passive hyperthermia. More recently, executive function (EF) testing during exercise has been addressed to assess changes in performance with some level of active hyperthermia. The purpose of the present study was to employ both external thermal stress and active hyperthermia in order to assess changes in executive function (EF) tasks within varying environmental temperatures before, during, and after a maximal treadmill test. Nine apparently healthy college-aged males participated in two trials of a Bruce protocol treadmill test in hot (35°C) …

The Effects Of An Energy Drink (Monster) On Muscular Strength, Muscualr Fatigue, And Speed, Gene Paez Jr., Michael L. Daniel

International Journal of Exercise Science: Conference Proceedings

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12-Lead Ecg Abnormalities In Ncaa Division Ii Women's Basketball Athlete, Sarah N. Fulfer, Jennifer Blevins-Mcnaughton

International Journal of Exercise Science: Conference Proceedings

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Validity Of A Nutrition Knowledge Questionnaire For Adults With Intellectual Disability, Brooke Marie Bouza

International Journal of Exercise Science: Conference Proceedings

Nutrition professionals consider individuals with intellectual disabilities to be nutritionally vulnerable or at risk for becoming overweight or obese. Presently there is limited empirical evidence regarding the nutritional habits and education of individuals with intellectual disabilities. Currently the Special Olympics Healthy Athletes program has become the largest global public health organization dedicated to serving people with intellectual disabilities. In 2012, Special Olympics Texas provided nearly 1,600 health screenings to athletes. The screenings provide surveillance information for public health organizations in the use of health planning, prevention, and promotion. The purpose of this study was to examine the validity of a …

Isokinetic Fatigue Characteristics For The Leg Extensors Versus Flexors, Elias M. Carrillo, Matt S. Stock, Jacob Adam Mota, Kendra D. Olinghouse, Alexander S. Drusch, Brennan J. Thompson

International Journal of Exercise Science: Conference Proceedings

Maximal isokinetic muscle actions are often used in research studies to examine fatigability and even estimate muscle fiber-type. However, the majority of previous investigations have examined these topics for the leg extensors (i.e., quadriceps), and we are unaware of investigations that have specifically assessed the fatigue characteristics for the flexors (i.e., hamstrings). The purpose of this study was to compare the percent decline values for the leg extensors versus flexors for 50 and 100 repeated, maximal concentric isokinetic muscle actions. Fifteen healthy men (mean ± SD age = 23 ± 3 years; body mass = 94.1 ± 11.9 kg) with …

Effect Of Resistance Exercise Intensity On The Mrna Expression Of Pgc-1Α Isoforms In Human Skeletal Muscle, Neil A. Schwarz, Sarah K. Mckinley, Mike Spillane, Joshua J. Gann, Thomas L. Andre, Darryn S. Willoughby

International Journal of Exercise Science: Conference Proceedings

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Bilateral Avulsion Fracture, Morgan N. Suski, Airika Phillips

International Journal of Exercise Science: Conference Proceedings

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Inhibition Of Pim And Axl Kinases As Potential Treatments For A Variety Of Hematological Malignancies And Solid Tumors, Kent James Carpenter

Theses and Dissertations

This thesis is divided into three chapters. In each case, the goal is to achieve inhibition of a growth kinase (PIM or AXL) and subsequent arrest of cell growth and induction of apoptosis (in vitro cell culture models) or decrease in tumor volume (in vivo xenograft studies). Chapter one and chapter two discuss inhibition of proviral integration site for Moloneymurine leukemia virus (PIM) kinases. The three PIM kinases, PIM-1, PIM-2, and PIM-3, are a subfamily of serine/threonine kinases that are known to be involved in signaling pathways as downstream effectors of signal transducer and activator of transcription-5 (STAT5) signaling and …

Validation Of A 3-Dimensional Video Motion Capture System For Determining Barbell Power And Velocity During The Bench Press, Ac Fry, L Bradford, T Herda, J Weir Facsm, M Lane, M Andre, A Hudy, J Siedlik

International Journal of Exercise Science: Conference Proceedings

Andrew C. Fry, Luke Bradford, Trent Herda, Joseph Weir FACSM, Michael Lane, Matthew Andre, Andrea Hudy, J. Deckert and J. Siedlik.Neuromechanics Laboratory and Kansas Athletics Inc., University of Kansas, Lawrence, KS

Analyses of barbell kinetics and kinematics have typically required the use of force plates, tether-based position transducers, or digitized video analysis. PURPOSE: To determine the validity of a 3-dimensional video markerless motion capture system for determining barbell kinetics and kinematics. METHODS: Two 3-D video cameras sampling at 30 Hz and mounted on the top of a power rack were interfaced with a self-contained computer and software system, and operated …

Relationships Between Salivary Cortisol And Speed Squat Power And Velocity In Elite Collegiate Basketball Players, Mj Andre, Ac Fry, Pr Dietz, Gj Cain, A Hudy

International Journal of Exercise Science: Conference Proceedings

Matthew J. Andre, Andrew C. Fry, Patricia R. Dietz, Glenn J. Cain, Andrea Hudy; University of Kansas, Lawrence, KS

Studies have found inverse relationships between salivary cortisol and vertical jump, standing broad jump, and peak force and rate of force development (isometric mid-thigh pull) in athletes. However, to our knowledge, no study has determined the relationship between salivary cortisol and power and velocity during barbell speed squats. PURPOSE: Therefore, the purpose of this study was to determine the relationship between salivary cortisol and power and velocity during barbell speed squats in elite collegiate basketball players. METHODS: Ten NCAA Division I …

Convergent Validity Of Physical Activity Devices In Adults With Unilateral Transtibial Amputation: Case Study, Cm Veal, D Crawford, J New, Cp Dionne, Sb Sisson

International Journal of Exercise Science: Conference Proceedings

C.M. Veal¹, D. Crawford², J. New¹, C.P. Dionne²,S.B. Sisson¹; ¹Department of Nutritional Sciences, University of Oklahoma Health Sciences Center, Oklahoma City, OK ²Department of Rehabilitation Sciences, University of Oklahoma Health Sciences Center, Oklahoma City, OK

PURPOSE: To determine convergent validity of physical activity device measurement in adults with unilateral transtibial amputation for step count, time in light physical activity (LPA), time in moderate physical activity (MPA), and classification of physical activity (PA) intensity. METHODS: Adults with unilateral transtibial amputation (n=2) voluntarily participated in this single-visit, lab-based assessment. Exclusion …

Changes In Strength And Power Variables From Pre- To Post-Competitive Season In Collegiate Cheerleaders, C Proctor, Sr Wilson, Aj Bruenger

International Journal of Exercise Science: Conference Proceedings

Caroline Proctor, Steven R. Wilson, & Adam J. Bruenger; University of Central Arkansas, Conway, AR

Research performed on cheerleading focuses on injury rates. There is minimal research about strength and power levels of cheerleaders (CL) and how these variables change during a season. These variables may be a factor for the high injury rates experienced by CL. PURPOSE: To measure body composition, strength, and vertical jump ability before and after a cheerleading season. METHODS: 36 collegiate CL (23 Females; age = 20 ± 1 y; height = 65 ± 3 in; weight = 124 ± 18 lb;13 Males; age = …

Comparison Of Kinetic And Kinematic Variables During Jump Station And Markerless Motion Capture Vertical Jumps, R Pierce, D Heller, N Moodie

International Journal of Exercise Science: Conference Proceedings

Robert Pierce, Dave Heller, and Nicole Moodie; Rockhurst University; email: [email protected]

A previous study conducted in our lab revealed a significant difference in vertical jump measures obtained by using a standard jump station and markerless motion capture. PURPOSE: The purpose of this study was to determine if kinematic and kinetic variables contributed to differences in vertical jump height. METHODS: Seventeen recreationally active college subjects (9 male, 9 female) volunteered to participate in this study. Subjects reported to a motion capture facility for one testing session. Following a five minute jog warm-up, subjects completed three randomized trials of three …

Meg Final Report, Jeff Edwards, John Smith

Journal of Undergraduate Research

The objectives of this award were met, especially in regard to the mentoring focus of the award. The students have been mentored and trained in an effective manner as outlined in my Mentoring Plan (see below). This includes mentoring students in research, writing, publishing, presenting at conferences, acceptance to professional schools, etc. Indeed, all the students graduating from my lab during this time were accepted to the professional school of their choice (see students listed below). Research, especially where the students are actually involved in all aspects of it including data collection and analysis, as well as publishing can play …

Role Of Primary Cilia In Osteoarthritis, David Kooyman

Journal of Undergraduate Research

Mentoring in my lab in 2012 has led to both tangible and intangible results. The tangible results for this year include two posters presented at an international meeting by undergraduate students, ORCA grants received by two students, international recognition by a team of undergraduate students, two papers published, three papers in preparation to be submitted within 30 days. The intangible results come as students return from interviews to medical and dental schools with stories of how confident they felt talking about their research. They also come in the form of the excitement I see in students when they talk about …

Ampk Activation In Aged Skeletal Muscle After Muscle Contraction, David M. Thomson

Journal of Undergraduate Research

The purpose of this mentoring environment grant was to determine the effect of aging on skeletal muscle AMPK intracellular localization and activation by muscle contraction. Funding for the project is now completed. The primary research objectives and findings are listed below:

Can Between-The-Legs Front Throw Distance Be Predicted From Overhead Back Throw Distance?, H. Weiss, B. Meyer, L. Taylor

International Journal of Exercise Science: Conference Proceedings

Please view abstract in the attached PDF file.

Effects Of Prematurity On The Presence Of Weibel-Palade Bodies In Human Umbilical Vein Endothelial Cells In Situ, Niloufar Tabatabeai, Dr. John S. Gardner

Journal of Undergraduate Research

Newbom, premature infants have greater susceptibility to infection compared to older newborn infants. Although the reason for greater susceptibility to bacterial infection in premature infants is unknown, there are many reports that focus on neutrophils as the defective cell type in the immature neonatal system. However, it was recently reported by Lorant et al. that in a rat model of inflammation, neutrophils from adult rats failed to migrate efficiently in neonatal rats.’ Furthermore, we found that this defect was associated with decreased expression of Pselectin on the surface of neonatal endothelial cells in situ.

Regulation Of The Transcription Factor Creb In Skeletal Muscle After Exercise, David M. Thomson

Journal of Undergraduate Research

My laboratory is running quite smoothly now. The students in the laboratory are proficient in performing experiments, obtaining data and interpreting it. My first undergraduate students have recently graduated, and I now have a nice array of experienced and newer inexperienced students, so the work is moving forward steadily, both in terms of productivity and of student training. I enjoy seeing students come into the lab with essentially no knowledge of laboratory techniques and the particular physiological topics that we study, and within a couple of months gaining enough knowledge to contribute to an intellectual discussion of the principles we …

Microsome Isolation From Tissue, Maria Bodero, Jose Francisco Abisambra

Sanders-Brown Center on Aging Faculty Publications

This protocol details the extraction of microsomes from frozen tissue in order to further examine the protein-protein interactions occurring within the endoplasmic reticulum. This protocol was adapted from Abisambra et al. (2013) with modifications made in order to optimize for subsequent use.

The Abcs Of The Ribosome, Kurt Fredrick, Michael Ibba

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

An ABC protein that binds the ribosomal exit site suggests a new mechanism for direct regulation of translation in response to changing ATP levels in the cell.

Psychological Contracts In Information Exchanges, Stanislav Mamonov

Dissertations, Theses, and Capstone Projects

Information assets continue to grow in importance of contribution to economic activity. Many emergent businesses, including Google, Amazon and Facebook, leverage crowd-sourced information assets as essential pillars supporting their business models. The appropriation of rights to information assets is commonly done through legal contracts. In practice this approach often fails to prevent conflicts between the information contributors and the companies claiming information rights. In research presented here I attempt to understand when and why the conflicts arise. I draw on psychological contract theory and I develop the framework of psychological contracts in information exchanges. I propose that intellectual property and …

The Role Of Interleukin-6, C-Fos And C-Jun In Adrenal Secretion, D. Craig Seager, Dr. Allan M. Judd

Journal of Undergraduate Research

The secretions of the adrenal gland are responsible for the body’s response to stress. One of the major mechanisms by which these secretions are regulated is by the way of the hypothalamuspituitary- adrenal axis (HPA axis). However, it was suspected that other mechanisms exist that are utilized by the body in order to up or down regulate adrenal secretions. One adrenal secretion, cortisol, is of special interest due to its great abundance and various effects in the body. Cortisol levels are generally regulated by ACTH, which is released by the pituitary. However, it was also shown to be increased by …

Does Respiratory Response At Altitude Lead To A Variation In Blood Oxygen Concentrations Among Individuals, Robert Adams, Dr. Robert Conlee

Journal of Undergraduate Research

Oxygen is the essential element in the air we breathe. The concentration of oxygen is constant in the atmosphere at approximately 21%. However barometric pressure is not constant throughout the atmosphere. The barometric pressure measures the amount of pressure the particles in the atmosphere exert and varies depending on altitude and weather. At sea level the barometric pressure is 760mmHg. The oxygen molecules accessible for respiration exert 21% of that pressure. The pressure of these oxygen molecules is 160mmHg and is referred to as the partial pressure of oxygen. As the altitude increases the total barometric pressure decreases from 760mmHg …

Primate Energy Eexpenditure And Life History, Herman Pontzer, David A. Raichlen, Adam D. Gordon, Kara K. Schroepfer-Walker, Brian Hare, Matthew C. O’Neill, Kathleen M. Muldoon

Dartmouth Scholarship

Humans and other primates are distinct among placental mammals in having exceptionally slow rates of growth, reproduction, and aging. Primates’ slow life history schedules are generally thought to reflect an evolved strategy of allocating energy away from growth and reproduction and toward somatic investment, particularly to the development and maintenance of large brains. Here we examine an alternative explanation: that primates’ slow life histories reflect low total energy expenditure (TEE) (kilocalories per day) relative to other placental mammals. We compared doubly labeled water measurements of TEE among 17 primate species with similar measures for other placental mammals. We found that …

Self-Determined Engagement In Physical Activity And Sedentary Behaviors Of Us College Students, Ale Quartiroli, Hotaka Maeda

International Journal of Exercise Science

International Journal of Exercise Science 7(1) : 87-97, 2014. Although the importance of promoting physical activity is well established, researchers have recently considered “sedentary behaviors” as another key risk factor for chronic disease.However, little is known about the motivational processes regulating sedentary behavior on a daily basis. A substantial amount of research has been based on the self-determination theory to examine the motivational processes regulating physical activity behaviors. However, only limited attention has been paid to sedentary behaviors from this theoretical perspective. This study aims to identify and understand motivational aspects related to sedentary behavior from a self-determination perspective. A …

Psychosocial Factors Related To Children’S Active School Travel: A Comparison Of Two European Regions, David Mcminn, David A. Rowe, Shemane Murtagh, Norah M. Nelson, Ivan Čuk, Almir Atiković, Mojca Peček, Gavin Breslin, Elaine M. Murtagh, Marie H. Murphy

International Journal of Exercise Science

International Journal of Exercise Science 7(1) : 75-86, 2014. Inequalities in health-behaviors exist between regions of Europe, along a North West/South East axis. This study investigated whether prevalence of walking to school and associated psychosocial antecedents differed between these two European regions. Participants were 1,263 children aged 7-11 years, from five countries. Children from North West Europe (n = 641) and South East Europe (n = 622) completed a school travel questionnaire that measured demographics, school commuting mode, travel companion, feelings about their local area, and Theory of Planned Behavior (TPB) variables related to walking to school. Multivariate analysis of …

The Lived Experience Of An In-Season Concussion Amongst Ncaa Division I Student-Athletes, Matthew S. Moreau, Jody L. Langdon, Thomas A. Buckley

International Journal of Exercise Science

International Journal of Exercise Science 7(1) : 62-74, 2014. The clinical presentation and recovery from a sports-related concussion has been well-documented in the sports medicine literature; however, the post-injury experience of the injured individual has been largely unexplored. Therefore, the purpose of this study was to examine collegiate student-athletes’ lived experiences of an in-season concussion. Four NCAA Division I student-athletes who suffered an in-season concussion were interviewed utilizing an existential phenomenological approach to capture the lived experience of the injury. Five major themes developed from the participants’ experiences: 1) symptoms and emotional response to injury, 2) experiences of concussion testing, …