Physiology Commons^™

Phase- Specific Changes In Rate Of Force Development And Muscle Morphology Throughout A Block Periodized Training Cycle In Weightlifters, Dylan G. Suarez, Satoshi Mizuguchi, William Guy Hornsby, Aaron J. Cunanan, Donald J. Marsh, Michael H. Stone

ETSU Faculty Works

The purpose of this study was to investigate the kinetic and morphological adaptations that occur during distinct phases of a block periodized training cycle in weightlifters. Athlete monitoring data from nine experienced collegiate weightlifters was used. Isometric mid-thigh pull (IMTP) and ultrasonography (US) results were compared to examine the effects of three specific phases of a training cycle leading up to a competition. During the high volume strength-endurance phase (SE) small depressions in rate of force development (RFD) but statistically significant (p ≤ 0.05) increases in vastus lateralis cross-sectional area (CSA), and body mass (BM) were observed. The lower volume …

Stimulatory Effect Of 5-Hydroxytryptamine (5-Ht) On Rat Capsaicin-Sensitive Lung Vagal Sensory Neurons Via Activation Of 5-Ht3 Receptors, Chun-Chun Hsu, Ting Ruan, Lu-Yuan Lee, You Shuei Lin

Physiology Faculty Publications

5-hydroxytryptamine (5-HT) is an inflammatory mediator known to be released in lung. Capsaicin-sensitive lung vagal (CSLV) afferents function as a primary sensor for detecting chemical stimuli and produce consequent reflexes during lung inflammation. To characterize the effect of 5-HT on CSLV afferents, responses of cardiorespiratory reflexes and single-unit C-fiber afferents to right-atrial injections of 5-HT were investigated in anesthetized Sprague-Dawley rats. Bolus injection of 5-HT (8 μg/kg) caused an immediate augmented breath and apnea, accompanied by hypotension and bradycardia. These initial responses were then followed by a brief pressor response and a more sustained depressor response. After a perineural treatment …

Time-Course Of Changes In Physiological, Psychological And Performance Markers Following A Functional-Fitness Competition, Ramires Alsamir Tibana, Jonato Prestes, Nuno Frade Sousa, Vinicius C. De Souza, Otávio De Tolêdo Nóbrega, Matheus Baffi, Carlos Ernesto S. Ferreira, Gabriel Veloso Cunha, James W. Navalta, Joice Cristina Dos Santos Trombeta, Cláudia R. Cavaglieri, Fabrício Azevedo Voltarelli

International Journal of Exercise Science

International Journal of Exercise Science 12(3): 904-918, 2019. Functional Fitness Training (FFT) programs are characterized by utilizing a high volume of training and using a variety of high intensity exercises. While FFT are growing in the number of practitioners and popularity, the relationship between physiological biomarkers and subjective scales in the specific context of FFT has not yet been evaluated in the literature. The purpose of the present study was to monitor the time-course response of cytokines (IL-10 and 1L-1b), immune variables (C-reactive protein -CRP and immunoglobulin A-IgA), hormonal milieu (cortisol-C, total testosterone-TT, free testosterone-FT and testosterone/cortisol-T/C ratio), creatine kinase-CK, …

Breathing Limited Air Situational Training Masks (Blastmask) Versus Self-Contained Breathing Apparatus (Scba) For Firefighters: A Pilot Study, Thomas Andre, Silvio Valladao, Shana Walsh, Derek Reisbeck

International Journal of Exercise Science

International Journal of Exercise Science 12(6): 941-949, 2019. Despite maintaining high levels of fitness, firefighters’ performance may be negatively impacted by the use of a Self-Contained Breathing Apparatus (SCBA), an essential piece of safety equipment worn during structural firefighting. Routine training with SCBAs can be cost-prohibitive and inefficient. The Breathing Limited Air Situational Training Mask (BlastMask) was developed as a training aid used to simulate the SCBA. The purpose of this study was to examine physiological and perceptual responses elicited by firefighters during steady state exercise when using the BlastMask compared to the SCBA. Current staff male firefighters (n …

The Impact Of Physical Activity And Sleep On Physiology Following A Mtbi, Garrett L. Lindsey, Alia Yasen, Anita Christie

International Journal of Exercise Science

International Journal of Exercise Science 12(3): 919-931, 2019. A mild traumatic brain injury (mTBI) is a common injury that happens to people across a range of lifestyles. Rest has been regarded as the most effective remedy to restore impaired physiological functions in those who have experienced this kind of injury. However, recent data suggests that a gradual increase in physical activity post-injury can lead to quicker recovery from negative symptoms. The impact of physical activity on physiologic recovery is not completely understood and the purpose of this study was to better understand how physical activity and sleep influence physiological outcomes …

Comparison Of College Student Hypertension Prevalence Between The Jnc7 And Acc/Aha Diagnostic Criteria, Kadiatu Kamara, Oliver W A Wilson, Zack Papalia, Melissa Bopp, C M. Bopp

International Journal of Exercise Science

International Journal of Exercise Science 12(3): 898-903, 2019. Hypertension is highly prevalent and associated with non-communicable diseases and increased premature mortality risk. However, the impact of the new hypertension diagnostic criteria on the prevalence of hypertension diagnoses has yet to be examined among college students. The purpose of this study was to compare the prevalence of hypertension between the JNC7 and the ACC/AHA hypertension diagnostic criteria among college students. The blood pressure of 5,945 college students was assessed, and chi-square tests for independence examined differences between JNC7 and ACC/AHA criteria. The mean age of participants was 21.30 ± 1.05 years, …

The Validity Of Resting Metabolic Rate (Rmr)-Prediction Equations And Reliability Of Measured Rmr In Female Athletes, Kelsi Mackay, Katie Schofield, Stacy Sims, Joseph Mcquillan, Matthew Driller

International Journal of Exercise Science

International Journal of Exercise Science 12(2): 886-897, 2019. The aim of the current study was to; 1) assess the test-retest reliability of an indirect calorimetry analyzer (Parvo Medics TrueOne), and 2) compare measured RMR with three RMR-predictive (pRMR) equations in female athletes. In part one, 12 recreationally-exercising women (mean ± SD; age 27.5 ± 12.3 y) performed two RMR assessments, on separate days, utilising the Parvo Medics TrueOne analyser. In part two, 25 recreationally-exercising women to sub-elite athletes (mean ± SD; age 30.1 ± 10.2 y) underwent an RMR assessment using the Parvo Medics TrueOne analyser, which was compared to …

Stress And Body Composition Of Juvenile Alligator Snapping Turtles (Macrochelys Temminckii), Brandon Scott Tappmeyer

Graduate Theses/Dissertations

The alligator snapping turtle (Macrochelys temminckii), is a species of conservation concern that is the subject of multiple head-start and reintroduction efforts across its range. In captive propagation programs, producing offspring that are in optimal physiological condition maximizes the likelihood of success after release. The purpose of my study was to compare stress and body composition between one free-ranging reintroduced population and two captive populations. The two captive populations were both housed in southern Oklahoma, but one group was reared indoors whereas the other inhabited outdoor ponds at a national fish hatchery. I used circulating glucocorticoid (corticosterone) concentrations as an …

Effects Of Home-Based Exercise Training Systems, Combined With Diet, On Cardiometabolic Health, Christian K. Roberts, David E. Segovia, Eli Lankford

International Journal of Exercise Science

International Journal of Exercise Science 12(2): 871-885, 2019. The efficacy of exercise training systems designed to be used in the home on cardiometabolic outcomes remains largely unknown. This investigation included two studies. Study 1 tested the effects a multi-exercise pulley system(NordicTrack Fusion CST with video trainer) and Study 2 an incline trainer (NordicTrack X22i with video trainer), both combined with daily food provision, for 12-weeks on indices of cardiometabolic health. Study 1 enrolled 27 adults (11 men, 16 women, 33.8±4.4 years of age) and Study 2 enrolled 29 adults (11 men, 18 women, 40.8±12.5 years of age). Pre- and post-intervention …

Age Dependent Regulation Of Cardiac Sodium Channel Gain Of Function, Madison Nowak, David Ryan King, Steven Poelzing, Seth Weinberg

Biology and Medicine Through Mathematics Conference

No abstract provided.

Hydration Status And Perception Of Fluid Loss In Male And Female University Rugby Union Players, Trev Muth, Robert C. Pritchett, Kelly Pritchett, James Depaepe, Rachael Blank

International Journal of Exercise Science

International Journal of Exercise Science 12(3): 859-870, 2019. Rugby union players are at risk for dehydration due to the high physiologic demand of the sport (~7.5 MJ/game). Dehydration could be due to lack of knowledge of fluid lost during activity. Therefore, the purpose of this study was to observe the hydration status and sweat loss estimations of male and female university rugby union players over three consecutive training sessions. Body mass, urine specific gravity (USG), and self-reported thirst scores were recorded pre and post training sessions. Sweat loss estimations were recorded post training session. After estimations, participants were shown his …

Lower-Body Power And Its Relationship With Body Drag Velocity In Law Enforcement Recruits, Matthew R. Moreno, Joseph M. Dulla, J. Jay Dawes, Robin (Rob) Marc Orr, Karly Cesario, Robert G. Lockie

International Journal of Exercise Science

International Journal of Exercise Science 12(4): 847-858, 2019. The body drag (BD) is used as a test to measure a law enforcement officer (LEO) recruit’s capability to rescue an individual. However, the physical characteristics associated with faster BD performance have not been identified. It could be expected that lower- body power, often measured via jump performance, could positively relate to BD performance. This study investigated the relationship between the vertical jump (VJ), peak anaerobic power measured in watts (PAPw), power-to-body mass ratio (P:BM), standing broad jump (SBJ), and relative SBJ, with BD velocity in LEO recruits. Retrospective analysis of data …

Self-Myofascial Release Does Not Improve Back Squat Range Of Motion, Alter Muscle Activation, Or Aid In Perceived Recovery 24-Hours Following Lower Body Resistance Training., Zach M. Beier, Ian L. Earp, John A. Korak

International Journal of Exercise Science

International Journal of Exercise Science 12(3): 839-846, 2019. Self-myofascial release (SMR) is an alternative therapy believed to increase myofascial mobility by exciting muscles and increasing blood flow to the treated area. Previous literature suggest SMR produces conflicting results on performance, muscle activation, range of motion (ROM), and recovery. This study was designed to utilize SMR on a fatigued individual prior to exercise and measure its’ effects on muscle activation, ROM, and perceived recovery compared to a dynamic warm-up session. The findings could help develop an efficient warm-up protocol for resistance-trained individuals. Electromyography (EMG) measured muscle activation of the rectus femoris …

Role Of Pkcbeta And Oxidant Signaling In Neonatal Pulmonary Hypertension, Joshua R. Sheak

Biomedical Sciences ETDs

Chronic hypoxia (CH)-induced vasoconstriction has been implicated in the pathogenesis of pulmonary hypertension (pHTN) in infants with chronic cardiorespiratory disorders. Although endothelial dysfunction, reduced nitric oxide (NO) bioavailability and oxidative stress contribute to a variety of cardiovascular disorders, their contribution to enhanced vasoconstrictor reactivity in neonatal pHTN is poorly understood. We therefore hypothesized that neonatal CH augments pulmonary vasoconstrictor reactivity by limiting NO-dependent pulmonary vasodilation and by promoting the generation of reactive oxygen species (ROS).

Enzymatic sources of ROS in the vasculature include NADPH oxidase isoforms, xanthine oxidase, and uncoupled endothelial nitric oxide synthase (eNOS). The mitochondria are also a …

Facilitation Of Neuropathic Pain By The Npy Y1 Receptor-Expressing Subpopulation Of Excitatory Interneurons In The Dorsal Horn, Tyler S. Nelson, Weisi Fu, Renee R. Donahue, Gregory F. Corder, Tomas Hökfelt, Ronald G. Wiley, Bradley K. Taylor

Physiology Faculty Publications

Endogenous neuropeptide Y (NPY) exerts long-lasting spinal inhibitory control of neuropathic pain, but its mechanism of action is complicated by the expression of its receptors at multiple sites in the dorsal horn: NPY Y1 receptors (Y1Rs) on post-synaptic neurons and both Y1Rs and Y2Rs at the central terminals of primary afferents. We found that Y1R-expressing spinal neurons contain multiple markers of excitatory but not inhibitory interneurons in the rat superficial dorsal horn. To test the relevance of this spinal population to the development and/or maintenance of acute and neuropathic pain, we selectively ablated Y1R-expressing interneurons with intrathecal administration of an …

Measurement Of Strength Gains Using A Fascial System Exercise Program, Michele M. Bond, Richard Lloyd, Robyn A. Braun, James A. Eldridge

International Journal of Exercise Science

International Journal of Exercise Science 12(1): 825-838, 2019. Current fascia research is allowing for an interdisciplinary understanding of the body’s anatomical, biomechanical, and neurological connectivity via the fascial network. Fascial research and its application has been validated and established in various clinical areas of research. The purpose of this study was to apply the current knowledge of the fascial system to general exercise protocols. This study involved 20 women, ages 30-60 years, who were novice weight trainers, mostly sedentary, and with no injuries, excessive pain or disease. The 10-week study compared strength gain changes between a strength training regimen control …

Rising Rural Body-Mass Index Is The Main Driver Of The Global Obesity Epidemic In Adults, Con Burns, Tara Coppinger, Janette Walton, Et Al

Publications

Body-mass index (BMI) has increased steadily in most countries in parallel with a rise in the proportion of the population who live in cities1,2. This has led to a widely reported view that urbanization is one of the most important drivers of the global rise in obesity3,4,5,6. Here we use 2,009 population-based studies, with measurements of height and weight in more than 112 million adults, to report national, regional and global trends in mean BMI segregated by place of residence (a rural or urban area) from 1985 to …

Recommendations For Measurement And Management Of An Elite Athlete, William Sands, Marco Cardinale, Jeni Mcneal, Steven Murray, Christopher Sole, Jacob Reed, Nikos Apostolopoulos, Michael H. Stone

ETSU Faculty Works

Athletes who merit the title ‘elite’ are rare and differ both quantitatively and qualitatively from athletes of lower qualifications. Serving and studying elite athletes may demand non-traditional approaches. Research involving elite athletes suffers because of the typical nomothetic requirements for large sample sizes and other statistical assumptions that do not apply to this population. Ideographic research uses single-athlete study designs, trend analyses, and statistical process control. Single-athlete designs seek to measure differences in repeated measurements under prescribed conditions, and trend analyses may permit systematic monitoring and prediction of future outcomes. Statistical process control uses control charting and other methods from …

Household Support For Physical Activity In Adolescent Girls Living In Primarily Low Socioeconomic Status Neighborhoods, Kristie Rupp, Sharon E. Taverno Ross, Tiffany L. Gary-Webb, Thomas Akiva, John M. Jakicic

International Journal of Exercise Science

International Journal of Exercise Science 12(5): 811-824, 2019. The purpose of this study was to examine the association between perception of household support and physical activity levels of adolescent girls living in primarily low socioeconomic status (SES) neighborhoods. The sample consisted of thirty-six adolescent girls (N=36; 60% non-Hispanic Black; mean age of 14.6 ± 1.3 [mean ± sd]; median body mass index (BMI) percentile of 90.5 [58.5, 97.0]) living in primarily low socioeconomic status (SES) neighborhoods. Trained researchers measured participants’ height and weight, and administered questionnaires to assess perception of household support for physical activity and minutes per day participating …

Development Of A Sonically Powered Biodegradable Nanogenerator For Bone Regeneration, Avi S. Patel

University Scholar Projects

Background: Reconstruction of bone fractures and defects remains a big challenge in orthopedic surgery. While regenerative engineering has advanced the field greatly using a combination of biomaterial scaffolds and stem cells, one matter of difficulty is inducing osteogenesis in these cells. Recent works have shown electricity’s ability to promote osteogenesis in stem cell lines when seeded in bone scaffolds; however, typical electrical stimulators are either (a) externally housed and require overcomplex percutaneous wires be connected to the implanted scaffold or (b) implanted non-degradable devices which contain toxic batteries and require invasive removal surgeries.

Objective: Here, we establish a biodegradable, piezoelectric …

Development Of A Sonically Powered Biodegradable Nanogenerator For Bone Regeneration, Avi Patel

Honors Scholar Theses

Background: Reconstruction of bone fractures and defects remains a big challenge in orthopedic surgery. While regenerative engineering has advanced the field greatly using a combination of biomaterial scaffolds and stem cells, one matter of difficulty is inducing osteogenesis in these cells. Recent works have shown electricity’s ability to promote osteogenesis in stem cell lines when seeded in bone scaffolds; however, typical electrical stimulators are either (a) externally housed and require overcomplex percutaneous wires be connected to the implanted scaffold or (b) implanted non-degradable devices which contain toxic batteries and require invasive removal surgeries.

Objective: Here, we establish a biodegradable, piezoelectric …

Eeg Responses To Incremental Self-Paced Cycling Exercise In Young And Middle Aged Adults, Rachel M. Maceri, Nicholas P. Cherup, Nicholas J. Hanson

International Journal of Exercise Science

International Journal of Exercise Science 12(3): 800-810, 2019. Electroencephalography (EEG) is a non-invasive method of measuring electrical activity of the brain during exercise. There is conflicting evidence as to how neural activity changes in relation to incremental exercise testing (IET), or if age has any effect. The purpose of this study was to determine 1) how brain activity changes throughout an IET, and 2) if age affects this response. 13 younger (age: 24.9 ± 2.6 years, 9 males) and 10 middle-aged (49.1 ± 3.2 years, 3 males) recreationally active individuals volunteered for this study. A self-paced, perceptually regulated IET was …

Cardio-Metabolic Disease Risk Factors Among South Asian Labour Migrants To The Middle East: A Scoping Review And Policy Analysis, Shiva Raj Mishra, Saruna Ghimire, Chandni Joshi, Bishal Gyawali, Archana Shrestha, Dinesh Neupane, Sudesh Raj Sharma, Yashashwi Pokharel, Salim S. Virani

School of Public Health Faculty Research

This paper aims to explore the burgeoning burden of cardiovascular and metabolic disease (CMD) risk factors among South Asian labor migrants to the Middle East. We conducted a qualitative synthesis of literature using PubMed/Medline and grey literature searches, supplemented by a policy review of policies from the South Asian countries. We found a high burden of cardio-metabolic risk factors among the migrants as well as among the populations in the home and the host countries. For example, two studies reported the prevalence of diabetes mellitus (DM) ranging between 9 and 17% among South Asian migrants. Overweight and obesity were highly …

A Dedicated Chaperone Mediates The Safe Transfer Of Mitoribosomal Proteins To Their Site Of Assembly, Gabrielle Ashley Hillman

Graduate School of Biomedical Sciences Theses and Dissertations

Mitochondrial ribosomes are functionally specialized for the synthesis of several essential inner membrane proteins of the respiratory chain. While remarkable progress has recently been made towards understanding the structure of mitoribosomes, the unique pathways and factors that facilitate their biogenesis remain largely unknown. This dissertation defines the physiological role of an evolutionarily conserved yeast protein called Mam33 in mitochondrial ribosome assembly. The biomedical relevance of this finding stems from the fact that mutations or changes in its expression of the human ortholog p32 result in mitochondrial dysfunction. In human patients, bi-allelic mutations cause severe multisystemic defects in mitochondrial energy metabolism, …

Association Of Oxidative Stress With Female Infertility - A Case Control Study, Faiza Alam, Taseer Ahmed Khan, Sofia Amjad, Rehana Rehman

Department of Biological & Biomedical Sciences

Objective: To compare stress markers and reproductive hormones in fertile and infertile females, and to relate the markers with age, duration and cause of infertility, and body mass index..
Methods: The case-control study was conducted at Aga Khan University Hospital, Karachi, from March 2017 to February 2018. Females aged 16-50 years regardless of ethnic background were recruited from the Australian Concept Infertility Medical Centre, Karachi, and were equally divided into infertile cases group A, and fertile controls group B. Serum follicular stimulating hormone, luteinizing hormone, estradiol, glutathione reductase and cortisol were measured using enzyme-linked innmunosorbent assay. SPSS 19 …

Comparison Of Post-Activation Potentiation Methods On Power And Sprint Acceleration, Aaron Piper

Electronic Theses and Dissertations

Post-activation potentiation (PAP) is a stimulus used to enhance performance by performing specific interventions prior to subsequent explosive movements. The purpose of this study was to determine the effect of different PAP methods on power and sprint acceleration in resistance trained, college-aged men and women. A total of 13 subjects participated in the study. After determining back squat 1 repetition max, subjects returned for testing on separate days to complete one of four interventions (dynamic resistance, weighted plyometric, isometric, or control) in a randomized order. A standardized warmup was given, followed by a baseline countermovement jump (CMJ) and 20-meter sprint. …

Human Anatomy And Physiology I: Course Map With Expected Learning Outcomes, Carlos Liachovitzky

Open Educational Resources

This document contains a list with all the Anatomy and Physiology I expected learning outcomes organized by topics, and grouped into ten units: 1. Introduction to A&P: body plan & organization; 2. Introduction to A&P: homeostasis; 3. The chemical level of organization; 4. Levels of organization: the cellular level of organization; 5. Levels of organization: the tissue level of organization; 6. Support and movement: integumentary system; 7. Support and movement: skeletal system & articulations; 8. Support and movement: muscular system; 9. Regulation, integration, and control: nervous system; 10. Regulation, integration, and control: special senses

Each learning outcome is referred to …

Food Traceability In School Foodservice Operations: Benefits And Challenges, Basem Boutros, Kevin Roberts, Naiqing Lin, Kevin Sauer

Health and Sport Science Faculty Publications

Purpose/Objectives: This study explored food traceability systems in school foodservice in the United States and the potential benefits and challenges to their implementation.

Methods: An online questionnaire was developed and used to collect data. A mixed-mode approach was followed to recruit the participants. A convenience sample of 500 school nutrition professionals from Qualtrics panel was targeted for data collection with the goal of having responses from 300 participants. Due to low response rate from the initial panel, the contact information of a second convenience sample of 200 child nutrition professionals with no geographic representation was obtained from the National Center …

A Mixed-Methods Approach To Understanding The Relationship Between Mental Toughness And The Effect Of Music On Exercise Performance, Kayla Baker

Electronic Theses and Dissertations

Previous research has investigated the use of music as an ergogenic aid for exercise performance; however, the effect of music on exercise may differ between individuals of varying levels of mental toughness (MT). Purpose: The purpose of this study is to examine the moderating effect of MT on the effect of listening to music during exercise. Methods: The current study used a counter-balanced design, utilizing a mixed-methods approach. Thirty-one recreationally-active individuals (22.13 ± 2.11 yrs, 1.73 ± .10 m, 75.68 ± 14.67 kg, 42.89 ± 5.31 mL·kg·min-1; 65.5% males) were recruited for this study. Participants completed an initial visit to …

The Effects Of Salinity On Zootechnical Performance Of Spotted Seatrout (Cynoscion Nebulosus) In Recirculating Aquaculture Systems, Eric Gigli

Master's Theses

The spotted seatrout (Cynoscion nebulosus) is a euryhaline finfish candidate for marine aquaculture in the northern Gulf of Mexico. Aquaculture of this species currently uses salinities of 25 psu or greater making production challenging in areas where high salinity water is not available. This study aimed to document the effects of salinity on zootechnical performance of spotted seatrout embryos, early larvae, and juveniles in recirculating aquaculture systems to assist with the development of protocols for low salinity culture.

Embryos obtained from a volitional spawn at 29 psu were incubated at three salinities (12.5, 18.75, or 25 psu) until …