Untrained Position-Encoded Multilayer Perceptron Network For Structured Illumination Microscopy Reconstruction,
2026
Indian Institute of Technology Delhi
Untrained Position-Encoded Multilayer Perceptron Network For Structured Illumination Microscopy Reconstruction, Sahil Sharma, Leonidas Zimianitis, Krishnendu Samanta, Balpreet Singh Ahluwalia, Joby Joseph, Dushan N. Wadduwage
Computer Science Faculty Publications
Structured Illumination Microscopy (SIM) enables super-resolution imaging by encoding high-frequency spatial information through patterned light. While traditional Fourier-based reconstruction methods are prone to artifacts under suboptimal conditions, recent deep learning approaches often require large training datasets and lack adaptability across different imaging setups. In this work, we present Position Encoded Multi-Layer Perceptron (PEM) network that leverages implicit neural representations (INRs) and SIM forward-model-driven modeling to reconstruct super-resolved images without any training data. PEM-SIM represents each spatial coordinate as a combination of sinusoidal functions across multiple frequencies, enabling rich encoding of fine spatial detail. A forward model grounded in SIM image …
Adaptive Self-Attention For Enhanced Segmentation Of Adult Gliomas In Multi-Modal Mri,
2026
Old Dominion University
Adaptive Self-Attention For Enhanced Segmentation Of Adult Gliomas In Multi-Modal Mri, Evan P. Savaria, Jiangwen Sun
Computer Science Faculty Publications
Every year there are an estimated 80,000–90,000 new glioma cases, highlighting the need for reliable imaging-based decision support. Although deep learning has improved tumor sub-region segmentation, many state-of-the-art models fail to fully capture complementary information across T1, T1Gd, T2, and FLAIR MRI modalities and often operate as “black boxes,” limiting physician trust when precise delineation is critical for surgical planning, radiation targeting, and treatment monitoring. To address these limitations, we propose AIMS, an Adaptive Integrated Multi-Modal Segmentation framework that maintains modality-specific feature streams and employs adaptive self-attention within a hierarchical CNN-Transformer architecture to prioritize and fuse multi-modal MRI features. We …
Forcing A Molecule To Switch: Quantifying Mechanical Control At The Atomic Scale,
2026
Old Dominion University
Forcing A Molecule To Switch: Quantifying Mechanical Control At The Atomic Scale, A. M. Shashika D. Wijerathna, Markus Zirnheld, Michael L. Hildebrand, Myles Perry, Marjorie Cenese, Yuan Zhang
Physics Faculty Publications
Mechanically induced conformational switching at the single-molecule level represents a fundamental mechanism for molecular functionality, yet quantitative characterization of the underlying force and energy landscape remains limited. Here, we study individual TBrPP-Co(II) molecules on Au(111) using qPlus atomic force microscopy. By reconstructing interaction potentials from 3D Δf(x,y,z) data, we determine a threshold force of ∼96 ± 8 pN and a tip-induced switching interaction energy of ∼38 ± 4 meV associate with the conformational transition. The isolated tip-molecule force follows a power law (exponent ∼6), indicating dominance of long-range van der Waals interactions. …
Computational Modeling Of Bubble Dispersion In Alginate Hydrogel Foams For Radiologically Equivalent Biomedical Phantoms,
2026
University Central of Florida
Computational Modeling Of Bubble Dispersion In Alginate Hydrogel Foams For Radiologically Equivalent Biomedical Phantoms, Godson N. Brako
Graduate Studies Theses and Dissertations 2026
The foaming of hydrogels presents a promising strategy for tailoring mechanical and radiological properties to replicate biological soft tissues for biomedical phantoms. Achieving uniform and predictable void fraction distributions in alginate hydrogel foams remains a challenge due to the complex interplay between bubble dynamics, matrix rheology, and interfacial forces during the pre-gelation aeration stage. This thesis develops a Computational Fluid Dynamics framework using the transient Eulerian two-fluid approach to predict void fraction distribution in alginate hydrogel precursor solutions aerated by air injection through a bottom nozzle. The objective is to use the framework for design of the foaming system to …
Recent Insight And Perspective Of Marine-Inspired Biopolymers For Wound Healing Applications - A Review,
2026
Qatar University
Recent Insight And Perspective Of Marine-Inspired Biopolymers For Wound Healing Applications - A Review, Muhammad Umar Aslam Khan, Saiqa Yousaf, Abdalla Abdal-Hay, Mohd Faizal Bin Abdullah, Sahar Madani, Muhammad Shahzad Zafar, Goran M. Stojanović, Lobat Tayebi
Electrical & Computer Engineering Faculty Publications
There is an increasing necessity for advanced, sustainable, and biocompatible materials for wound healing as therapeutic and diagnostic products. Marine environments, characterized by high biodiversity, offer an underutilized source of natural resources with enormous potential for creating novel materials for dressings. This review highlights the revolutionary nature of polymeric biomaterials of marine origin, with a focus on polysaccharides, like alginate, chitosan, and carrageenan; proteins, such as collagen and gelatin. These biopolymers are outstanding in their physicochemical properties, such as biodegradability, bioactivity, and modifiable mechanical strength, which enable their use in wound-healing systems. Besides, these biomaterials may be easily chemically and …
Recent Advances In Bioceramics, Fundamental Properties And Future Perspective In Biomedical Applications ‒ A Review,
2026
The First Affiliated Hospital of Lishui University
Recent Advances In Bioceramics, Fundamental Properties And Future Perspective In Biomedical Applications ‒ A Review, Ayesha Younas, Muhammad Umar Aslam Khan, Mohd Faizal Binte Abdullah, Lobat Tayebi, Shuanghu Wang, Abdalla Abdal-Hay, Yichi Xu
Electrical & Computer Engineering Faculty Publications
Bioceramics are important biomaterials in biomedical engineering because of their biocompatibility, bioactivity, osteoconductivity, and structural resemblance to actual bone tissue. In recent years, materials science and nanotechnology have enabled the use of bioceramics in bone regeneration, dental restoration, tissue engineering, drug delivery systems, and implantable medical devices. This comprehensive review covers advances in bioceramics, including calcium phosphates, hydroxyapatite (HAp), tricalcium phosphate, bioactive glasses, zirconia, alumina, and multifunctional ceramic nanocomposites. Priority is given to techniques such as additive manufacturing, 3D printing, sol-gel processing, electrospinning, and nanostructuring to improve mechanical strength, porosity, bioactivity, and cell interactions. Recent advances include ion doping, surface …
Application Of A Hyaluronic Acid-Based Lotions Containing Hydroxyapatite Nano-Particles Approach For Treatment Of Initial Dental Caries,
2026
Shahid Beheshti University of Medical Sciences
Application Of A Hyaluronic Acid-Based Lotions Containing Hydroxyapatite Nano-Particles Approach For Treatment Of Initial Dental Caries, Zahra Gharavi, Zahra Namazi, Fatemehsadat Pishbin, Helia Givian, Maryam Torshabi, Farhood Najafi, Parisa Amdjadi
Electrical & Computer Engineering Faculty Publications
This study evaluated the remineralization potential of a ceramic–polyelectrolyte system, based on a novel combination of hydroxyapatite nanoparticles (HAp NPs) and a hyaluronic acid (HY) matrix, for dental enamel, a tissue that remains challenging to repair in clinical dentistry. Nano-Hydroxyapatite (nanoHAp) powder was synthesized and characterized using X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR), field-emission scanning electron microscopy (FE-SEM), dynamic light scattering (DLS), and zeta potential analysis to confirm their crystalline structure, functional groups, morphology, particle size distribution, and colloidal stability. HY-based suspensions (remineralizing lotions) containing 5, 10, and 12 wt% of the synthesized nanoHAp particles were formulated via a …
3d-Printed Alginate Scaffolds Incorporated With Synergistic Strontium/Magnesium - Doped Bioglass Nanoparticles For Bone Regeneration: An In Vivo Evaluation In Rabbit Cranial Defects,
2026
Mashhad University of Medical Sciences
3d-Printed Alginate Scaffolds Incorporated With Synergistic Strontium/Magnesium - Doped Bioglass Nanoparticles For Bone Regeneration: An In Vivo Evaluation In Rabbit Cranial Defects, Mehraneh Movahedi Aliabadi, Afsaneh Jahani, Seyed Majdoddin Vahidi Toorchi, Ali Moradi, Mohammad Hossein Ebrahimzadeh, Fatemeh Kalalinia, Farkhonde Sarhaddi, Lobat Tayebi, Nafiseh Jirofti
Electrical & Computer Engineering Faculty Publications
Nonunion fractures remain a major orthopedic challenge, highlighting the need for improved bone tissue engineering (BTE) strategies. This study hypothesized that incorporating Sr/Mg-doped 58S bioglass nanoparticles into 3D-printed alginate (Alg) scaffolds would improve their physicochemical, mechanical, and biological properties and enhance bone regeneration. Structural characterization showed that Sr/Mg-doping reduced bioglass size and produced interconnected porous scaffolds. Under wet conditions, Alg scaffold incorporating 2.5%Sr/Mg-doped 58S bioglass showed the highest Young’s modulus (0.4356 ± 0.0244 MPa), whereas under dry conditions, the Alg scaffold incorporating 5%Sr/Mg-doped 58S bioglass achieved the highest value (0.1945 ± 0.0519 MPa). In vitro studies demonstrated biocompatibility and enhanced …
A Low-Cost Fourier-Based Dual-Pump Mock Circulatory Loop For Arterial Pressure Waveform Reproduction,
2026
University of North Dakota
A Low-Cost Fourier-Based Dual-Pump Mock Circulatory Loop For Arterial Pressure Waveform Reproduction, Victor K. Tsui, Kouhyar Tavakolian, Daniel Ewert
Electrical & Computer Engineering Faculty Publications
Cardiovascular diseases are among the leading causes of death worldwide, creating a need for reliable hemodynamic testing platforms for cardiovascular device evaluation and therapeutic development. Mock circulatory loops (MCLs) provide effective in vitro platforms for reproducing physiological and pathological pressure conditions; however, many existing systems remain limited in programmability, waveform fidelity, standardization, and affordability. This study presents a cost-effective dual-pump hybrid MCL (hMCL) that independently regulates baseline and pulsatile pressure components using Fourier-based harmonic synthesis. Reference arterial pressure waveforms were decomposed into harmonic components, and their amplitudes, frequencies, and phase shifts were converted into pulse-width-modulation signals for dual-pump actuation. Validation …
Senescent Fibroblasts In Aging And Pulmonary Fibrosis,
2026
Biomedical and Translational Sciences
Senescent Fibroblasts In Aging And Pulmonary Fibrosis, Sara B. Palega, Aiwei Y. Borengasser, Yan Y. Sanders
Department of Biomedical and Translational Sciences Faculty Publications
Aging is a major risk factor for many chronic lung diseases, including Idiopathic Pulmonary Fibrosis (IPF), a fatal and incurable disease characterized by progressive fibrotic remodeling. Age-associated structural alterations, impaired regenerative capacity, and dysregulated cellular signaling collectively create a pro-fibrotic microenvironment. A central driver of this pathological shift is the accumulation of senescent cells, which undergo irreversible growth arrest and develop a robust pro-inflammatory senescence-associated secretory phenotype (SASP). Emerging evidence identifies senescent lung fibroblasts as critical mediators of IPF pathogenesis. These cells promote excessive extracellular matrix deposition, myofibroblast differentiation, and tissue stiffening, while simultaneously impairing epithelial regeneration. Together, these effects …
Yk-4-250, A Synthetic Telmisartan-Tempol Conjugate: Crystal Structure Of A Stabilized Free Radical Containing An Angiotensin At₁ Receptor Inhibitor,
2026
Virginia Commonwealth University
Yk-4-250, A Synthetic Telmisartan-Tempol Conjugate: Crystal Structure Of A Stabilized Free Radical Containing An Angiotensin At₁ Receptor Inhibitor, Simon Friedrich, Yali Kong, Faik N. Musayev, Milton L. Brown, B. Frank Gupton
Department of Biomedical and Translational Sciences Faculty Publications
We report the first crystal structure of the telmisartan-tempol conjugate 2,2,6,6-tetramethyl-1-(λ'-oxidaneyl)piperidin-4-yl 4'-[(1,7'-dimethyl-2'-propyl-1H,3'H-[2,5'-bibenzo[d]imidazol]-3'-yl)methyl]-[1,1'-biphenyl]-2-carboxylate free radical (YK-4-250, C₄₂H₄₆N₅O₃), a dual-function inhibitor designed to target both the angiotensin II type 1 receptor (AT₁R) and reactive oxygen species (ROS). Structural analysis reveals a unique crystal architecture in which the nitroxide radical is stabilized within a sterically protected environment while preserving the telmisartan pharmacophore essential for high-affinity receptor antagonism. YK-4-250 is a novel small-molecule conjugate of telmisartan and tempol that incorporates a catalytic stabilized nitroxide radical and was rationally designed to mitigate gastrointestinal acute radiation syndrome (GI-ARS).
Parametric Study Of Yields And Properties Of Corn Stover-Derived Hydrothermal Liquefaction Products By Using Statistical Approaches,
2026
Old Dominion University
Parametric Study Of Yields And Properties Of Corn Stover-Derived Hydrothermal Liquefaction Products By Using Statistical Approaches, Isamu Umeda, Meicen Liu, Jiefu Wang, Yi Zheng, Zhiwu Wang, Jaya Shankar Tumuluru, Sandeep Kumar
Civil & Environmental Engineering Faculty Publications
Hydrothermal liquefaction (HTL) of lignocellulosic biomass produces multiple product fractions, including solid residue (SR), heavy bio-oil (HBO), aqueous phase (AP), and light bio-oil (LBO). This study mainly applied principal component analysis (PCA) and regression modeling to predict AP solution weight, LBO weight and fuel characteristics, and HTL wastewater biodegradability, as well as to improve prediction accuracy for SR and HBO under various operating conditions (temperature: 250–350 °C, residence time: 5–60 min, and the combined solid loading of three batches: 15–45 g). A complementary relationship between SR and AP weights found in PCA enabled the estimation of AP weight based on …
Eeg And Imu Gait Signal Processing: A Comparative Assessment Of The "Reza" Exponential Filter And Classic Filters,
2026
Macon & Joan Brock Virginia Health Sciences at Old Dominion University
Eeg And Imu Gait Signal Processing: A Comparative Assessment Of The "Reza" Exponential Filter And Classic Filters, Reza Pousti, Daniel M. Russell, Derek C. Monroe, Christopher K. Rhea
Rehabilitation Sciences Faculty Publications
Noise degrades both EEG and gait signals, and classical IIR filters (Butterworth, Chebyshev, elliptic) involve trade-offs between passband flatness, ripple, and roll-off. This study compared a novel exponential "Reza" filter with these designs for neural and locomotor data. We analyzed an open-source mobile brain-body imaging dataset with EEG and gait data from 49 healthy adults (EEG: 256-channel, 512 Hz; IMUs: six APDM Opals, 128 Hz). EEG channels were grand-averaged and band-pass filtered at 0.5-50 Hz, while IMU axes were averaged and band-pass filtered at 0.5-5 Hz. The outcomes were signal-to-noise ratio SNR (dB) and band-integrated Welch PSD (EEG:0.5-50 Hz; IMU:0.5-5 …
Effect Of Local Steel Slag Incorporation On The Mechanical Properties Of Concrete,
2025
Civil Engineering Department, College of Engineering, Al-Mustansiriyah University, Baghdad/Iraq
Effect Of Local Steel Slag Incorporation On The Mechanical Properties Of Concrete, Ahmed Safaa Tariq Karmah, Wissam Khadum Alsaraj, Luma A. Zghair
Al-Esraa University College Journal for Engineering Sciences
The increasing interest in the production of concrete through the utilization of inexpensive materials has caused a rise in the number of studies concerning the use of materials with cementitious properties, such as Silica Fume, Slag, Fly Ash and other pozzolanic materials. Moreover, the increasing amounts of Steel Slag being produced from local factories that are being deposited without an available method of disposal provides an opportunity to harness the Slag in the production of an inexpensive, and possibly better concrete. Slag has been used as both an addition and substitution of the cement and fine aggregate. The mixtures included …
Decoding Climate Change: A Comprehensive Statistical Insight Into Temperature Anomalies In Iraq And Its Neighboring Countries,
2025
AL-Furat Al-Awsat Technical University, Mechanical Power Department,54001/Iraq
Decoding Climate Change: A Comprehensive Statistical Insight Into Temperature Anomalies In Iraq And Its Neighboring Countries, Jameel T. Al-Naffakha, Mohammed R. Al-Qassabanda, Israa Jafar
Al-Esraa University College Journal for Engineering Sciences
This study applies advanced statistical techniques, including the Mann-Kendall Trend Test and ARIMA forecasting, to validate and predict temperature anomalies across Iraq and its neighboring countries (2014–2024). Findings confirm a statistically significant warming trend (p < 0.00000005) across all nations, with Syria (1.02°C) and Turkey (0.97°C) experiencing the highest anomalies. GIS-based spatial analysis highlights regional disparities, identifying climate-vulnerable zones. The persistent rise in temperature anomalies correlates with worsening water scarcity, desertification, and extreme weather events, including prolonged droughts and heatwaves. Iraq’s peak anomaly (1.48°C) has exacerbated heat stress, agricultural decline, and reduced river inflows, while Kuwait and Saudi Arabia struggle to maintain critical infrastructure under record-breaking temperatures exceeding 50°C. These climate shifts pose severe risks to water availability, food security, and energy demand, necessitating urgent policy interventions. Key recommendations include enhanced water resource management, climate-adaptive agriculture, and renewable energy expansion. If left unaddressed, rising temperatures could destabilize the region, increasing socio-economic vulnerabilities and escalating resource conflicts. This study underscores the need for cross-border collaboration and sustainable adaptation policies to mitigate the long-term impacts of climate change in the Middle East.
Optimal Power Flow Control In The Iraqi Power Grid Using Artificial Intelligence Algorithms For Carbon Emission Reduction,
2025
Islamic Azad University, Islamic Republic of Iran
Optimal Power Flow Control In The Iraqi Power Grid Using Artificial Intelligence Algorithms For Carbon Emission Reduction, Mohammed Shakir Juber
Al-Esraa University College Journal for Engineering Sciences
Iraq’s power sector remains in a protracted and severe crisis characterized by a significant mismatch between supply and demand, high levels of losses during transmission and distribution, as well as an increasing challenge to the resources base being largely unfavourably. These inefficiencies impose heavy costs on the national economy in excess of 40 billion annually and they also reinforce greenhouse gas emissions, and exacerbate environmental issues. To deal with these problems, we proposed in this paper that a new hybrid AI tool should be developed for the solution of multi-objective optimization problem based on purpose Genetic Algorithm (GA) merger with …
Applying Machine Learning Techniques For Early Detection Of Cyber Attacks On Iot Devices,
2025
Researcher, Islamic Azad University, Islamic Republic of Iran
Applying Machine Learning Techniques For Early Detection Of Cyber Attacks On Iot Devices, Noor Adnan Allamy
Al-Esraa University College Journal for Engineering Sciences
This research designs, implements, and evaluates a machine learning-based framework for the early detection of cyber attacks targeting Internet of Things (IoT) devices, with a specific focus on the context and challenges present in Iraq. The study conducts a comparative analysis of three supervised learning algorithms—Support Vector Machine (SVM), Random Forest (RF), and Deep Neural Networks (DNN)—using a combination of benchmark datasets (NSL-KDD, CIC-IDS-2017, Bot-IoT) and a synthesized dataset adapted to simulate the Iraqi threat landscape. Key performance metrics, including accuracy, precision, recall, and F1-score, were used for evaluation. The proposed Random Forest model demonstrated superior performance, achieving an accuracy …
Ai-Enhanced Heat Transfer Optimization In Magnetic Bio-Nanofluids,
2025
Ministry of Reconstruction, Housing, Municipalities, and Public Works, Baghdad/Iraq
Ai-Enhanced Heat Transfer Optimization In Magnetic Bio-Nanofluids, Hasan Attyah Shaboot
Al-Esraa University College Journal for Engineering Sciences
This study presents a hybrid Artificial Intelligence–Computational Fluid Dynamics (AI-CFD) framework for optimizing heat transfer in magnetic bio-nanofluids subjected to external magnetic fields. Magnetic bio-nanofluids, composed of biocompatible base fluids containing superparamagnetic nanoparticles, exhibit tunable thermal and flow behavior, making them promising for biomedical and micro-cooling applications. Conventional optimization methods based on experiments or brute-force CFD are computationally expensive and limited in exploring the full design space. To overcome these challenges, an Artificial Neural Network (ANN) surrogate model was developed to predict two key performance indicators, the Nusselt number and the friction factor, with high accuracy (R² > 0.997). The surrogate …
Hybrid Experimental–Computational Study On The Energy Absorption Of Graphene Nanoplatelet-Reinforced Sandwich Structures,
2025
Ministry of Higher Education and Scientific Research, University of Mustansiriyah, Baghdad/Iraq
Hybrid Experimental–Computational Study On The Energy Absorption Of Graphene Nanoplatelet-Reinforced Sandwich Structures, Hamdan Yousif Hamdan
Al-Esraa University College Journal for Engineering Sciences
Background: Sandwich composites are widely used in aerospace, automotive, and marine applications because of their lightweight, stiffness, and strength, but they remain prone to out-of-plane impacts and barely visible impact damage (BVID). Graphene Nanoplatelets (GNPs) have shown strong potential to improve fracture toughness and impact resistance. However, hybrid experimental–computational studies applying such reinforcement are still lacking in developing contexts like Iraq, where practical and accessible solutions are essential. Aims: The study investigates the effect of GNP reinforcement on the low-velocity impact behavior and energy absorption of glass fiber/epoxy sandwich panels with PVC foam and balsa wood cores. Objectives include fabricating …
Effect Of Thick Closed Walls Of West And South Elevations Of Iraqi Middle And South Territory Housing Building On Reducing Energy Use,
2025
University of Mustansiriyah, College of Engineering, Dept. of Architecture Baghdad/Iraq
Effect Of Thick Closed Walls Of West And South Elevations Of Iraqi Middle And South Territory Housing Building On Reducing Energy Use, Abeer Qasim Jbur, Shaimaa M. Hamza, Mayyadah Lutfi Abdulwahhab
Al-Esraa University College Journal for Engineering Sciences
Thermal insulation is one of the most important factors in achieving sustainability, increasing efficiency, and reducing energy consumption, but modern insulation materials are expensive, in addition to their availability. Therefore, through our research, we resorted to investigating the issue of reducing thermal load in buildings through the use of thick-walled facades in the southern and western facades, where we studied a building with two windows with windows on the southern and western facades and another without these windows and with thick walls, for two locations, the first in central Iraq, which is the city of Baghdad, and the second in …
