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Tissue Clearing As A Mechanism To Identify Changes In Fibronectin Structure During Breast Cancer Metastasis, Maryam Nuru, Kelsey Hopkins, Luis Solorio 2018 Purdue University

Tissue Clearing As A Mechanism To Identify Changes In Fibronectin Structure During Breast Cancer Metastasis, Maryam Nuru, Kelsey Hopkins, Luis Solorio

The Summer Undergraduate Research Fellowship (SURF) Symposium

With metastasis accounting for approximately 90% of breast cancer deaths and an alarming number of over 300,000 new breast cancer cases to be diagnosed by the end of 2018, there is growing need to understand the process of breast cancer. Changes in the extracellular matrix (ECM) of the tumor microenvironment play an essential role in this deadly tumor progression. Specifically, the glycoprotein fibronectin (FN), has been identified to be up-regulated in patients with worse clinical outcomes. During tumor progression fibronectin undergoes conformational changes that aid in metastatic dissemination. In order to analyze the dynamic changes in FN expression and ...


Efficacy Of Smart Infusion Pumps From A Nursing Perspective, Kassi B. Zaborowski 2018 University of Tennessee Health Science Center

Efficacy Of Smart Infusion Pumps From A Nursing Perspective, Kassi B. Zaborowski

Applied Research Projects

In today’s healthcare, intravenous (IV) therapy-related errors have become rampant and are responsible for a substantial portion of hospital injuries and deaths. In the last decade, however, since the development and implementation of “smart” IV pumps, a significant number of these IV medication errors have allegedly been reduced. The purpose of this paper is to discuss research surrounding an evaluation of the efficacy of smart IV pumps from a nursing perspective.


A Cyber-Physical System Framework For Early Detection Of Paroxysmal Diseases, Zuxing Gu, Yu Jiang, Min Zhou, Xiaoyu Song, Lui Sha 2018 Tsinghua University

A Cyber-Physical System Framework For Early Detection Of Paroxysmal Diseases, Zuxing Gu, Yu Jiang, Min Zhou, Xiaoyu Song, Lui Sha

Computer Science Faculty Publications and Presentations

Paroxysmal diseases of inpatients are globally recognized as one of the top challenges in medicine. Poor clinical outcomes are primarily caused by delayed recognition, especially due to diverse clinical diagnostic criteria with complex manifestations, irregular episodes, and already overloaded clinical activities. With the proliferation of measuring devices and increased computational capabilities, cyber-physical characterization plays an increasingly important role in many domains to provide enabling technologies. This paper presents a cyber-physical system (CPS) framework to assist physicians in making earlier diagnoses of paroxysmal sympathetic hyperactivity based on existing medical knowledge. We propose a configurable diagnostic knowledge model to characterize clinical criteria ...


El Impacto De Las Artes Visuales En Personas Afectadas Por Cáncer, Bettina Ingham 2018 EXPLORARTE

El Impacto De Las Artes Visuales En Personas Afectadas Por Cáncer, Bettina Ingham

ICOT 18 - International Conference on Thinking - Cultivating Mindsets for Global Citizens

El impacto de las artes visuales en el bienestar y la mejora de la calidad de vida de personas afectadas por cáncer.

Un programa diseñado para poner en práctica e investigar el alcance que tienen las artes visuales y el método de Estrategias de Pensamiento Visual para el desarrollo de habilidades de pensamiento que promueven la identificación y expresión verbal de las emociones, minimizando, en el caso de las personas convalecientes, el sufrimiento que va desde el dolor de la enfermedad hasta el miedo a la muerte.

Los efectos que la contemplación (percepción estética), el análisis y la práctica(proceso ...


Assistive Utensil: A Spork For Hand Tremors And Spatial Awareness, Ana Font Hernandez, Jacob Kabariti, Troy Taylor 2018 City University of New York (CUNY)

Assistive Utensil: A Spork For Hand Tremors And Spatial Awareness, Ana Font Hernandez, Jacob Kabariti, Troy Taylor

Publications and Research

In this poster, we present a 3D printed solution for hand tremors and special awareness. Our spork is an assistive device designed and 3D printed for patients suffering from scleroderma, systemic sclerosis, Parkinson's, multiple sclerosis, drug withdrawal, etc. The scale-based handle will act as a counterweight to offset the contents on the other end and reduce shakiness. The larger grip allows an easy and comfortable hold. The product will be 3D printed for a customizable fit and at an affordable price. Lastly, the product will include a haptic feedback sensor to assist the visually impaired in locating food contents ...


In Vitro Aortic Arch Flow Model For Vector Flow Imaging Testing, Jackson Mosley 2018 University of Arkansas, Fayetteville

In Vitro Aortic Arch Flow Model For Vector Flow Imaging Testing, Jackson Mosley

Biomedical Engineering Undergraduate Honors Theses

Pediatric stenosis is the narrowing of the aorta at the aortic valve, above the aortic valve, or below the aortic valve. Typically, this disease’s severity is diagnosed by conventional Doppler ultrasound methods, or echocardiography. Conventional Doppler can sometimes overestimate the pressure gradient over the area of stenosis, diagnosing some cases of PAS to be more severe than they actually are. This causes earlier intervention than is desired in children. A new US modality, Vector Flow Imaging (VFI), is an angle-independent US imaging method that can potentially more accurately quantify peak blood flow velocities and pressure gradients across stenotic sections ...


Failure Of Primary Total Knee Arthroplasty: Establishing A Baseline For Retrieval Analysis Using Well-Functioning Necropsy Specimens, Meredith Perkins 2018 University of Tennessee Health Science Center

Failure Of Primary Total Knee Arthroplasty: Establishing A Baseline For Retrieval Analysis Using Well-Functioning Necropsy Specimens, Meredith Perkins

Theses and Dissertations (ETD)

Introduction. Total knee arthroplasty (TKA) is an effective treatment for end-stage osteoarthritis of the knee. While many patients have positive functional and pain outcomes following primary TKA, a subset of patients have suboptimal outcomes, such as unexplained pain or aseptic loosening of the implant components necessitating revision of the index procedure. The understanding of the exact etiology of these suboptimal outcomes of primary TKA is in its infancy. In order to elucidate the etiology of failure in primary TKAs, a baseline for the factors contributing to arthroplasty failure and dissatisfaction must first be established. The purpose of this study was ...


Raman Spectral Analysis For Rapid Screening Of Dengue Infection, Tahir Mahmood, Haq Nawaz, A. Ditta, M.I. Majeed, M.A. Hanif, N. Rashid, H.N. Bhatti, H.F. Nargis, M. Saleem, Franck Bonnier, Hugh Byrne 2018 Department of Chemistry, University of Agriculture, Faisalabad, Pakistan.

Raman Spectral Analysis For Rapid Screening Of Dengue Infection, Tahir Mahmood, Haq Nawaz, A. Ditta, M.I. Majeed, M.A. Hanif, N. Rashid, H.N. Bhatti, H.F. Nargis, M. Saleem, Franck Bonnier, Hugh Byrne

Articles

Infection with the dengue virus is currently clinically detected according to different biomarkers in human blood plasma, commonly measured by enzyme linked immunosorbent assays, including non-structural proteins (Ns1), immunoglobulin M (IgM) and immunoglobulin G (IgG). However, there is little or no mutual correlation between the biomarkers, as demonstrated in this study by a comparison of their levels in samples from 17 patients. As an alternative, the label free, rapid screening technique, Raman spectroscopy has been used for the characterisation/diagnosis of healthy and dengue infected human blood plasma samples. In dengue positive samples, changes in specific Raman spectral bands associated ...


The Test-Retest Reliability Of Erp Components As Assessed By The Brief Neurometric Battery, James D. Cole, Paul Kieffaber 2018 The College of William and Mary

The Test-Retest Reliability Of Erp Components As Assessed By The Brief Neurometric Battery, James D. Cole, Paul Kieffaber

Undergraduate Honors Theses

Electroencephalography (EEG) has been a crucial component of neuropsychological research for nearly a century. Recent applications of the EEG recordings in a clinical setting have demonstrated a range of diagnostic and prognostic uses. Certain changes in event-related potentials (ERP) have been linked to the effects of different neurological conditions and can be accurately used to determine the severity of those conditions. However, in order to assess the stability of these ERP recordings over an extended period of time, one must first establish their statistical test-retest reliability. Using a novel Brief Neurometric Battery we assessed seven different ERP components in twenty ...


Policy Of Current Hospital Translation Services And Recommendations For Future Adjustments For Spanish-Speaking Patients, Isidora Rose Beach 2018 University of Tennessee, Knoxville

Policy Of Current Hospital Translation Services And Recommendations For Future Adjustments For Spanish-Speaking Patients, Isidora Rose Beach

University of Tennessee Honors Thesis Projects

No abstract provided.


Design And Development Of A Quartz Crystal Microbalance Immunosensor For Exosomes, Wesley Cox 2018 University of Tennessee, Knoxville

Design And Development Of A Quartz Crystal Microbalance Immunosensor For Exosomes, Wesley Cox

University of Tennessee Honors Thesis Projects

No abstract provided.


The Hospital Antimicrobial Use Process: From Beginning To End, William R. Truong, Jason Yamaki 2018 St. Joseph Hospital, Orange, CA

The Hospital Antimicrobial Use Process: From Beginning To End, William R. Truong, Jason Yamaki

Pharmacy Faculty Articles and Research

Hospital antimicrobial stewardship (AMS) programs are responsible for ensuring that all antimicrobials are utilized in the most appropriate and safe manner to improve patient outcomes, prevent adverse drug reactions, and prevent the development of antimicrobial resistance. This Perspectives article outlines the hospital antimicrobial use process (AUP), the foundational system that ensures that all antimicrobials are utilized in the most appropriate and safe manner. The AUP consists of the following steps: antimicrobial ordering, order verification, preparation and delivery, administration, monitoring, and discharge prescribing. AMS programs should determine how each step contributes to how an antimicrobial is used appropriately or inappropriately at ...


Use Of Urine Antigen Testing For Blastomyces In An Integrated Health System, Dennis J. Baumgardner 2018 Aurora UW Medical Group, Aurora Health Care

Use Of Urine Antigen Testing For Blastomyces In An Integrated Health System, Dennis J. Baumgardner

Journal of Patient-Centered Research and Reviews

Purpose: Blastomycosis, an endemic fungal infection, mimics many other diseases. We explored the use of Blastomyces urine antigen (BuAg), reportedly the most sensitive noninvasive test, in clinical practice and compared it to other noninvasive tests.

Methods: A total of 836 BuAg tests performed on unique patients (first test only) at one large integrated health system from June 2013 to May 2016 were retrospectively reviewed to examine test characteristics and demographic features. Of these, 100 cases from 2015, a year containing a large local blastomycosis outbreak, were randomly selected for detailed analysis.

Results: Demographics for the BuAg-tested population: mean age 54 ...


Open Cycle: Forecasting Ovulation For Family Planning, Karen Clark, Mridul Jain, Araya Messa, Vinh Le, Eric C. Larson 2018 Southern Methodist University

Open Cycle: Forecasting Ovulation For Family Planning, Karen Clark, Mridul Jain, Araya Messa, Vinh Le, Eric C. Larson

SMU Data Science Review

Abstract: Forecasting the length and different phases of a woman’s menstrual cycle, especially ovulation, is an important aspect of family planning. Predicting fertility has many uses in family planning including avoiding pregnancy and assisting couples in becoming pregnant. Past methods have focused on monitoring basal body temperature (BBT), cervical mucus changes, and hormonal levels to determine fertility. While these methods can provide an accurate prediction of ovulation these tests can become expensive, time-consuming, and do not provide prediction until after ovulation has occurred. In this paper, we compare conventional fertility assessment that is based on a rule known as ...


Physical Therapy Practices Of The Us And South America, Dylan Young Vazquez 2018 Carroll College

Physical Therapy Practices Of The Us And South America, Dylan Young Vazquez

Carroll College Student Undergraduate Research Festival

The research for this presentation will explore the differences in the field of physical therapy between the United States and various countries in South America to compare and evaluate the preparation and implementation of physical therapy care, to formulate recommendations for possible improvements and pursue further research. The United States and selected South American countries have starkly different economic, social, and political backgrounds which impact the way in which physical therapy is administered and received. This allows for comparisons to be made between each respective model of physical therapy, creating a running dialog on how these programs can improve and ...


Transcranial Direct Current Stimulation (Tdcs) Improves Performance On Spelling And Word Detection Tasks, J. Kevin Wilson 2018 University of New Mexico

Transcranial Direct Current Stimulation (Tdcs) Improves Performance On Spelling And Word Detection Tasks, J. Kevin Wilson

Psychology ETDs

Deficits in written language involving spelling can have negative effects on a person’s education and occupation. Conventional spelling therapy is a time consuming and cost-prohibitive option, if even available, highlighting the need for improved methods for remediation. One possible way to address this need may be through the use of transcranial direct current stimulation (tDCS). This study sought to examine the effects of tDCS on performance during spelling, word detection, and facial recognition tasks. Active or sham tDCS was randomly assigned to typically functioning adults. The anode electrode was placed over Broca’s area (F7 in the 10/20 ...


Resource Review: 5minuteconsult, Ivan Armando Portillo 2018 Chapman University

Resource Review: 5minuteconsult, Ivan Armando Portillo

Library Articles and Research

A product review of 5MinuteConsult, an online resource from WoltersKluwer "designed to help health care professionals and clinical students by providing information that is needed at the point-of-care".


Comparación Evaluativa De La Preparación E Implementación De Fisioterapia Entre Los Estados Unidos Y Los Países Seleccionados De América Del Sur, Dylan Young Vazquez 2018 Carroll College

Comparación Evaluativa De La Preparación E Implementación De Fisioterapia Entre Los Estados Unidos Y Los Países Seleccionados De América Del Sur, Dylan Young Vazquez

Languages and Literature Undergraduate Student Works

The research for this comparative analysis explores the differences in the field of physical therapy between the United States and various countries in South America to compare and evaluate the forms of preparation and implementation of care, to formulate recommendations within areas for further research to be pursued. The United States and South American countries have starkly different economic, social, and political backgrounds which impact the way in which physical therapy is administered and received. This allows for comparisons to be made between each respective model of physical therapy, creating a running dialog on how these programs can improve and ...


Therapeutic Effects Of Instrument-Assisted Soft Tissue Mobilization And The Use In Athletic Populations: A Literature Review, Jenna Treloar 2018 University of Nebraska-Lincoln

Therapeutic Effects Of Instrument-Assisted Soft Tissue Mobilization And The Use In Athletic Populations: A Literature Review, Jenna Treloar

Honors Theses, University of Nebraska-Lincoln

This literature review examines the mechanism and application of instrument-assisted soft tissue mobilization (IASTM) in athletic populations. IASTM is a treatment technique used for soft tissue pathologies. Experimental studies have been performed to determine the effects of IASTM on range of motion, pain, and inflammation in upper and lower extremities. Conflicting evidence exists for the effect of IASTM on the inflammatory reparative process of the body while more evidence exists in support of the technique’s benefits on pain reduction and improvement in range of motion. Understanding the effects of IASTM on range of motion, pain, and inflammation may be ...


Concussion Competencies: A Framework For School-Based Concussion Management (Flyer), Arthur C. Maerlender, Jonathan Lichtenstein, Jennifer Parent-Nichols 2018 University of Nebraska-Lincoln

Concussion Competencies: A Framework For School-Based Concussion Management (Flyer), Arthur C. Maerlender, Jonathan Lichtenstein, Jennifer Parent-Nichols

Center for Brain, Biology and Behavior: Papers & Publications

This volume grew out of many years of clinical practice, research, and program projects. It is the culmination of more than 50 years of work with kids, brains, and schools. While there is research behind the Competencies and the underlying content, the intent was to create a user-friendly manual that cut across levels of responsibility and care. Concussion Competencies was not intended to be a textbook in the traditional manner; however, the Competencies have been shown to be a useful approach to teaching this material.

This volume is organized around a set of Competencies that have been shown to be ...


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