Ultrasound Use In Resource-Limited Settings: A Systematic Review, 2018 Virginia Commonwealth University; Penn State Health Milton S. Hershey Medical Center
Ultrasound Use In Resource-Limited Settings: A Systematic Review, Ravindra Gopaul, Gonzalo Bearman, Michael P. Stevens
Journal of Global Radiology
Purpose: Over the past decade, ultrasound (US) machines have become smaller, less expensive, more reliable, durable and user-friendly, making ultrasonography an ideal imaging modality in resource-poor settings. We conducted a literature review to examine the use of ultrasound in resource-limited settings, with emphasis on common applications, barriers to implementation, and impact on clinical decision-making and patient disposition.
Methods and Materials: Literature review. We conducted a PubMed and Cochrane Central search on the clinical use of ultrasound in the developing world. Search terms included ultrasonography, developing countries, resource limited, remote setting, poverty, and low income. Articles from 2000 to 2015 that ...
The Chapman Bone Algorithm: A Diagnostic Alternative For The Evaluation Of Osteoporosis, 2018 Chapman University
The Chapman Bone Algorithm: A Diagnostic Alternative For The Evaluation Of Osteoporosis, Elise Levesque, Anton Ketterer, Wajiha Memon, Cameron James, Noah Barrett, Cyril Rakovski, Frank Frisch
Mathematics, Physics, and Computer Science Faculty Articles and Research
Osteoporosis is the most common metabolic bone disease and goes largely undiagnosed throughout the world, due to the inaccessibility of DXA machines. Multivariate analyses of serum bone turnover markers were evaluated in 226 Orange County, California, residents with the intent to determine if serum osteocalcin and serum pyridinoline cross-links could be used to detect the onset of osteoporosis as effectively as a DXA scan. Descriptive analyses of the demographic and lab characteristics of the participants were performed through frequency, means and standard deviation estimations. We implemented logistic regression modeling to find the best classification algorithm for osteoporosis. All calculations and ...
Tissue Clearing As A Mechanism To Identify Changes In Fibronectin Structure During Breast Cancer Metastasis, Maryam Nuru, Kelsey Hopkins, Luis Solorio
The Summer Undergraduate Research Fellowship (SURF) Symposium
With metastasis accounting for approximately 90% of breast cancer deaths and an alarming number of over 300,000 new breast cancer cases to be diagnosed by the end of 2018, there is growing need to understand the process of breast cancer. Changes in the extracellular matrix (ECM) of the tumor microenvironment play an essential role in this deadly tumor progression. Specifically, the glycoprotein fibronectin (FN), has been identified to be up-regulated in patients with worse clinical outcomes. During tumor progression fibronectin undergoes conformational changes that aid in metastatic dissemination. In order to analyze the dynamic changes in FN expression and ...
Efficacy Of Smart Infusion Pumps From A Nursing Perspective, 2018 University of Tennessee Health Science Center
Efficacy Of Smart Infusion Pumps From A Nursing Perspective, Kassi B. Zaborowski
Applied Research Projects
In today’s healthcare, intravenous (IV) therapy-related errors have become rampant and are responsible for a substantial portion of hospital injuries and deaths. In the last decade, however, since the development and implementation of “smart” IV pumps, a significant number of these IV medication errors have allegedly been reduced. The purpose of this paper is to discuss research surrounding an evaluation of the efficacy of smart IV pumps from a nursing perspective.
A Cyber-Physical System Framework For Early Detection Of Paroxysmal Diseases, 2018 Tsinghua University
A Cyber-Physical System Framework For Early Detection Of Paroxysmal Diseases, Zuxing Gu, Yu Jiang, Min Zhou, Xiaoyu Song, Lui Sha
Computer Science Faculty Publications and Presentations
Paroxysmal diseases of inpatients are globally recognized as one of the top challenges in medicine. Poor clinical outcomes are primarily caused by delayed recognition, especially due to diverse clinical diagnostic criteria with complex manifestations, irregular episodes, and already overloaded clinical activities. With the proliferation of measuring devices and increased computational capabilities, cyber-physical characterization plays an increasingly important role in many domains to provide enabling technologies. This paper presents a cyber-physical system (CPS) framework to assist physicians in making earlier diagnoses of paroxysmal sympathetic hyperactivity based on existing medical knowledge. We propose a configurable diagnostic knowledge model to characterize clinical criteria ...
Effects Of 8-Week Sensory Electrical Stimulation Combined With Motor Training On Eeg-Emg Coherence And Motor Function In Individuals With Stroke, 2018 National Yang-Ming University
Effects Of 8-Week Sensory Electrical Stimulation Combined With Motor Training On Eeg-Emg Coherence And Motor Function In Individuals With Stroke, Li-Ling Hope Pan, Wen-Wen Yang, Mei-Wun Tsai, Shun-Hwa Wei, Felipe Fregni, Vincent Chiun-Fan Chen, Li-Wei Chou
Engineering Science Faculty Publications
The peripheral sensory system is critical to regulating motor plasticity and motor recovery. Peripheral electrical stimulation (ES) can generate constant and adequate sensory input to influence the excitability of the motor cortex. The aim of this proof of concept study was to assess whether ES prior to each hand function training session for eight weeks can better improve neuromuscular control and hand function in chronic stroke individuals and change electroencephalography-electromyography (EEG-EMG) coherence, as compared to the control (sham ES). We recruited twelve subjects and randomly assigned them into ES and control groups. Both groups received 20-minute hand function training twice ...
El Impacto De Las Artes Visuales En Personas Afectadas Por Cáncer, 2018 EXPLORARTE
El Impacto De Las Artes Visuales En Personas Afectadas Por Cáncer, Bettina Ingham
ICOT 18 - International Conference on Thinking - Cultivating Mindsets for Global Citizens
El impacto de las artes visuales en el bienestar y la mejora de la calidad de vida de personas afectadas por cáncer.
Un programa diseñado para poner en práctica e investigar el alcance que tienen las artes visuales y el método de Estrategias de Pensamiento Visual para el desarrollo de habilidades de pensamiento que promueven la identificación y expresión verbal de las emociones, minimizando, en el caso de las personas convalecientes, el sufrimiento que va desde el dolor de la enfermedad hasta el miedo a la muerte.
Los efectos que la contemplación (percepción estética), el análisis y la práctica(proceso ...
Engineered Exosomes For Delivery Of Therapeutic Sirnas To Neurons, 2018 University of Massachusetts Medical School
Engineered Exosomes For Delivery Of Therapeutic Sirnas To Neurons, Reka A. Haraszti
GSBS Dissertations and Theses
Extracellular vesicles (EVs), exosomes and microvesicles, transfer endogenous RNAs between neurons over short and long distances. We have explored EVs for siRNA delivery to brain. (1) We optimized siRNA chemical modifications and siRNA conjugation to lipids for EV-mediated delivery. (2) We developed a GMP-compatible, scalable method to manufacture active EVs in bulk. (3) We characterized lipid and protein content of EVs in detail. (4) We established how protein and lipid composition relates to siRNA delivering activity of EVs, and we reverse engineered natural exosomes (small EVs) into artificial exosomes based on these data.
We established that cholesterol-conjugated siRNAs passively associate ...
Assistive Utensil: A Spork For Hand Tremors And Spatial Awareness, 2018 City University of New York (CUNY)
Assistive Utensil: A Spork For Hand Tremors And Spatial Awareness, Ana Font Hernandez, Jacob Kabariti, Troy Taylor
Publications and Research
In this poster, we present a 3D printed solution for hand tremors and special awareness. Our spork is an assistive device designed and 3D printed for patients suffering from scleroderma, systemic sclerosis, Parkinson's, multiple sclerosis, drug withdrawal, etc. The scale-based handle will act as a counterweight to offset the contents on the other end and reduce shakiness. The larger grip allows an easy and comfortable hold. The product will be 3D printed for a customizable fit and at an affordable price. Lastly, the product will include a haptic feedback sensor to assist the visually impaired in locating food contents ...
Failure Of Primary Total Knee Arthroplasty: Establishing A Baseline For Retrieval Analysis Using Well-Functioning Necropsy Specimens, 2018 University of Tennessee Health Science Center
Failure Of Primary Total Knee Arthroplasty: Establishing A Baseline For Retrieval Analysis Using Well-Functioning Necropsy Specimens, Meredith Perkins
Theses and Dissertations (ETD)
Introduction. Total knee arthroplasty (TKA) is an effective treatment for end-stage osteoarthritis of the knee. While many patients have positive functional and pain outcomes following primary TKA, a subset of patients have suboptimal outcomes, such as unexplained pain or aseptic loosening of the implant components necessitating revision of the index procedure. The understanding of the exact etiology of these suboptimal outcomes of primary TKA is in its infancy. In order to elucidate the etiology of failure in primary TKAs, a baseline for the factors contributing to arthroplasty failure and dissatisfaction must first be established. The purpose of this study was ...
Policy Of Current Hospital Translation Services And Recommendations For Future Adjustments For Spanish-Speaking Patients, 2018 University of Tennessee, Knoxville
Policy Of Current Hospital Translation Services And Recommendations For Future Adjustments For Spanish-Speaking Patients, Isidora Rose Beach
University of Tennessee Honors Thesis Projects
No abstract provided.
Design And Development Of A Quartz Crystal Microbalance Immunosensor For Exosomes, 2018 University of Tennessee, Knoxville
Design And Development Of A Quartz Crystal Microbalance Immunosensor For Exosomes, Wesley Cox
University of Tennessee Honors Thesis Projects
No abstract provided.
In Vitro Aortic Arch Flow Model For Vector Flow Imaging Testing, 2018 University of Arkansas, Fayetteville
In Vitro Aortic Arch Flow Model For Vector Flow Imaging Testing, Jackson Mosley
Biomedical Engineering Undergraduate Honors Theses
Pediatric stenosis is the narrowing of the aorta at the aortic valve, above the aortic valve, or below the aortic valve. Typically, this disease’s severity is diagnosed by conventional Doppler ultrasound methods, or echocardiography. Conventional Doppler can sometimes overestimate the pressure gradient over the area of stenosis, diagnosing some cases of PAS to be more severe than they actually are. This causes earlier intervention than is desired in children. A new US modality, Vector Flow Imaging (VFI), is an angle-independent US imaging method that can potentially more accurately quantify peak blood flow velocities and pressure gradients across stenotic sections ...
Raman Spectral Analysis For Rapid Screening Of Dengue Infection, 2018 Department of Chemistry, University of Agriculture, Faisalabad, Pakistan.
Raman Spectral Analysis For Rapid Screening Of Dengue Infection, Tahir Mahmood, Haq Nawaz, A. Ditta, M.I. Majeed, M.A. Hanif, N. Rashid, H.N. Bhatti, H.F. Nargis, M. Saleem, Franck Bonnier, Hugh Byrne
Infection with the dengue virus is currently clinically detected according to different biomarkers in human blood plasma, commonly measured by enzyme linked immunosorbent assays, including non-structural proteins (Ns1), immunoglobulin M (IgM) and immunoglobulin G (IgG). However, there is little or no mutual correlation between the biomarkers, as demonstrated in this study by a comparison of their levels in samples from 17 patients. As an alternative, the label free, rapid screening technique, Raman spectroscopy has been used for the characterisation/diagnosis of healthy and dengue infected human blood plasma samples. In dengue positive samples, changes in specific Raman spectral bands associated ...
Clinical Applications Of Infrared And Raman Spectroscopy: State Of Play And Future Challenges, 2018 University of Strathclyde
Clinical Applications Of Infrared And Raman Spectroscopy: State Of Play And Future Challenges, Matthew Baker, Hugh Byrne, John Chalmers, Peter Gardner, Royston Goodacre, Alex Henderson, Sergei Kazarian, Francis Martin, Julian Moger, Nick Stone, Josep Sule-Suso
Vibrational spectroscopies, based on Infrared absorption and/or Raman scattering provide a detailed fingerprint of a material, based on the chemical content. Diagnostic and prognostic tools based on these technologies have the potential to revolutionise our clinical systems leading to improved patient outcome, more efficient public services and significant economic savings. However, despite these strong drivers, there are many fundamental scientific and technological challenges which have limited the implementation of this technology in the clinical arena, although recent years have seen significant progress in addressing these challenges. This review examines (i) the state of the art of clinical applications of ...
The Test-Retest Reliability Of Erp Components As Assessed By The Brief Neurometric Battery, 2018 The College of William and Mary
The Test-Retest Reliability Of Erp Components As Assessed By The Brief Neurometric Battery, James D. Cole, Paul Kieffaber
Undergraduate Honors Theses
Electroencephalography (EEG) has been a crucial component of neuropsychological research for nearly a century. Recent applications of the EEG recordings in a clinical setting have demonstrated a range of diagnostic and prognostic uses. Certain changes in event-related potentials (ERP) have been linked to the effects of different neurological conditions and can be accurately used to determine the severity of those conditions. However, in order to assess the stability of these ERP recordings over an extended period of time, one must first establish their statistical test-retest reliability. Using a novel Brief Neurometric Battery we assessed seven different ERP components in twenty ...
The Hospital Antimicrobial Use Process: From Beginning To End, 2018 St. Joseph Hospital, Orange, CA
The Hospital Antimicrobial Use Process: From Beginning To End, William R. Truong, Jason Yamaki
Pharmacy Faculty Articles and Research
Hospital antimicrobial stewardship (AMS) programs are responsible for ensuring that all antimicrobials are utilized in the most appropriate and safe manner to improve patient outcomes, prevent adverse drug reactions, and prevent the development of antimicrobial resistance. This Perspectives article outlines the hospital antimicrobial use process (AUP), the foundational system that ensures that all antimicrobials are utilized in the most appropriate and safe manner. The AUP consists of the following steps: antimicrobial ordering, order verification, preparation and delivery, administration, monitoring, and discharge prescribing. AMS programs should determine how each step contributes to how an antimicrobial is used appropriately or inappropriately at ...
Use Of Urine Antigen Testing For Blastomyces In An Integrated Health System, 2018 Aurora UW Medical Group, Aurora Health Care
Use Of Urine Antigen Testing For Blastomyces In An Integrated Health System, Dennis J. Baumgardner
Journal of Patient-Centered Research and Reviews
Purpose: Blastomycosis, an endemic fungal infection, mimics many other diseases. We explored the use of Blastomyces urine antigen (BuAg), reportedly the most sensitive noninvasive test, in clinical practice and compared it to other noninvasive tests.
Methods: A total of 836 BuAg tests performed on unique patients (first test only) at one large integrated health system from June 2013 to May 2016 were retrospectively reviewed to examine test characteristics and demographic features. Of these, 100 cases from 2015, a year containing a large local blastomycosis outbreak, were randomly selected for detailed analysis.
Results: Demographics for the BuAg-tested population: mean age 54 ...
Open Cycle: Forecasting Ovulation For Family Planning, 2018 Southern Methodist University
Open Cycle: Forecasting Ovulation For Family Planning, Karen Clark, Mridul Jain, Araya Messa, Vinh Le, Eric C. Larson
SMU Data Science Review
Abstract: Forecasting the length and different phases of a woman’s menstrual cycle, especially ovulation, is an important aspect of family planning. Predicting fertility has many uses in family planning including avoiding pregnancy and assisting couples in becoming pregnant. Past methods have focused on monitoring basal body temperature (BBT), cervical mucus changes, and hormonal levels to determine fertility. While these methods can provide an accurate prediction of ovulation these tests can become expensive, time-consuming, and do not provide prediction until after ovulation has occurred. In this paper, we compare conventional fertility assessment that is based on a rule known as ...
Physical Therapy Practices Of The Us And South America, 2018 Carroll College
Physical Therapy Practices Of The Us And South America, Dylan Young Vazquez
Carroll College Student Undergraduate Research Festival
The research for this presentation will explore the differences in the field of physical therapy between the United States and various countries in South America to compare and evaluate the preparation and implementation of physical therapy care, to formulate recommendations for possible improvements and pursue further research. The United States and selected South American countries have starkly different economic, social, and political backgrounds which impact the way in which physical therapy is administered and received. This allows for comparisons to be made between each respective model of physical therapy, creating a running dialog on how these programs can improve and ...