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An Economic And Regulatory Analysis Of Breast Cancer Drugs Approved By The Us Food And Drug Administration, Abdullah Althomali 2023 Chapman University

An Economic And Regulatory Analysis Of Breast Cancer Drugs Approved By The Us Food And Drug Administration, Abdullah Althomali

Pharmaceutical Sciences (MS) Theses

Introduction

Breast cancer is the most common cancer among women and the leading cause of cancer death among women worldwide. The pharmacological options for breast cancer include chemotherapy, hormone therapy, targeted therapy, and immunotherapy, which are used for the prevention or treatment of breast cancer. This study assessed trends in FDA approvals and prices at the market entry of new drugs indicated for breast cancer in the period 1980-2022. The study also evaluated the factors associated with the price of the new breast cancer drugs at market entry.

Material and Methods

Regulatory data were collected from the FDA website, and …


The Influences Of The Public Health Care System And Education System On The Economic Growth Of Swaziland, Grace Greer 2023 University of Arkansas, Fayetteville

The Influences Of The Public Health Care System And Education System On The Economic Growth Of Swaziland, Grace Greer

International and Global Studies Undergraduate Honors Theses

The Kingdom of Eswatini, also known as Swaziland, has one of the youngest populations in the world with over 70% of citizens being under the age of 18 years old. This creates a substantial opportunity for economic, social, and educational growth in a country previously plagued with diseases such as HIV/AIDS, poor health care infrastructure cutting off thousands from basic care, and an educational system with a very low attendance rate and an even lower graduation rate. By evaluating the root causes of such issues dating back to the colonial era there is an opportunity to reprioritize health care and …


Us Public School Demand For Locally Produced Meat And Poultry, Shara Akat 2023 University of Nebraska-Lincoln

Us Public School Demand For Locally Produced Meat And Poultry, Shara Akat

Department of Agricultural Economics: Dissertations, Theses, and Student Research

The objective of the USDA Farm-to-School program is to promote the understanding and use of local food in school education and meals. The hope is that by reconnecting students with how food is raised and purchasing the product from local producers it will increase nutrition and reduce food insecurity and obesity among students while simultaneously increasing economic activity for local producers. Most studies evaluating the federal program have focused on how the economic outcomes for local producers or student related health outcomes and primarily using fresh fruits and vegetables. Fundamental to either of these outcomes is understanding the schools’ demand …


Developing The Food Navigator Role At Everyone's Harvest, Chase Rodriguez 2023 California State University, Monterey Bay

Developing The Food Navigator Role At Everyone's Harvest, Chase Rodriguez

Capstone Projects and Master's Theses

Everyone’s Harvest (EH) is a 501(c)(3) non-profit that operates farmers’ markets. In order to reduce hunger in Monterey County, Everyone's Harvest offers several food assistance programs for low-income people including the Market Match (MM) incentive program which matches CalFresh money, modern day food stamps, dollar for dollar. The problem is that in Monterey County 1 in 4 adults and 1 in 3 children are food insecure. The purpose of the Food Navigator (FN) at EH is to engage with the local community and connect low-income people with food assistance resources, primarily the MM program. This project was a role development …


Debt And The Medicare Eligibility Discontinuity: Disparate Effects Across Households, Olivia Falck 2023 University of Richmond

Debt And The Medicare Eligibility Discontinuity: Disparate Effects Across Households, Olivia Falck

Honors Theses

Public health insurance programs like Medicare and Medicaid have been shown to help reduce household debt caused by healthcare costs. The impact of health insurance literacy makes the relationship between public health programs and debt more ambiguous. The increasing complexity of Medicare raises the question of whether cost savings associated with enrollment might be mitigated by the complexity of choosing the ideal plan for those with low health insurance literacy. In this study, I utilize the Medicare eligibility cutoff at age 65 to implement a regression discontinuity design that analyzes the impact of Medicare eligibility on household debt and out …


A Prospective-Randomized Study: The Impact Of Four Different Caries Removal Method On Pain And Clinical Evaluations, Merve Aydemir, Serdar Bağlar 2023 Department of Restorative Dentistry, Faculty of Dentistry, Istanbul Aydın University, Istanbul, Turkey

A Prospective-Randomized Study: The Impact Of Four Different Caries Removal Method On Pain And Clinical Evaluations, Merve Aydemir, Serdar Bağlar

Journal of Dentistry Indonesia

Objective: There are many different methods for removing caries. In this study, to evaluate four caries removal methods in terms of patient comfort and to evaluate the clinical success of restorations according to modified-USPHS criteria. Methods: In 31 patients with at least 4 Class II caries in their posterior teeth, 4 teeth were randomly divided into four groups and 4 different methods (conventional method, Carisolv, Papacarie, Er-Cr:YSGG Laser) were used for caries removal. Pain formation during caries removal was determined by FACE Pain Scale questionnaire. The restorations were controlled with Modified-USPHS criteria in 3-6-12 months period. Mann-Whitney U …


Treatment Of Oral Vascular Malformations With Ethamolin: A Report Of Two Cases, Maria Clara de Moura Santos Coelho Ferreira, Marco Vinícius de Sales Lima, Anna Laura Almeida Barreto, Dárcio Kitakawa, Alexandre do Prado Scherma, Felipe Peralta, Luis Felipe das Chagas e Silva de Carvalho 2023 Departamento de odontologia, Universidade de Taubaté, Taubaté, São Paulo, Brazil

Treatment Of Oral Vascular Malformations With Ethamolin: A Report Of Two Cases, Maria Clara De Moura Santos Coelho Ferreira, Marco Vinícius De Sales Lima, Anna Laura Almeida Barreto, Dárcio Kitakawa, Alexandre Do Prado Scherma, Felipe Peralta, Luis Felipe Das Chagas E Silva De Carvalho

Journal of Dentistry Indonesia

A hemangioma is a benign vascular neoplasm, relatively common in the head and neck. In the oral region, it affects the tongue, gums, mucosa, palate, and lip. Its size can vary from millimeters to centimeters, characterized as a purplish or reddish lesion. The present study aims to present two clinical cases of hemangiomas, the first of a male patient treated by sclerotherapy and the second of a female patient in which she was treated with ethamolin and later surgical treatment. It was concluded that sclerotherapy, in addition to being a safe treatment, managed to drastically reduce the initial size of …


A Two-Year Retrospective Evaluation Of Cone Beam Computed Tomography Indications In Pediatric, Adolescent And Adult Patients, Zeynep Betül Arslan, Esra Ceren Tuğutlu 2023 Department of Oral and Maxillofacial Radiology, Faculty of Dentistry, Yıldırım Beyazıt University, Ankara, Turkey

A Two-Year Retrospective Evaluation Of Cone Beam Computed Tomography Indications In Pediatric, Adolescent And Adult Patients, Zeynep Betül Arslan, Esra Ceren Tuğutlu

Journal of Dentistry Indonesia

Objective: The objective was to evaluate cone-beam computed tomography (CBCT) indications and distribution in pediatric, adolescent and adult patients. Methods: A total of 1013 CBCT images were reviewed in detail from the electronic patient database. The patient’s age, gender, CBCT indications and acquisition sites, referral departments, reason for referral, incidental findings in the imaging field and the presence of artifacts in the CBCT images were all recorded. The European DIMITRA project recommendations were used to categorize CBCT indications in the children and the European Guidelines were used for adults. Results: From a total of 1013 images; 5.3% …


Treatment Of Gingival Fenestration Using Mucoperiosteal Flap With Connective Tissue Graft: A Report Of Two Cases, Swati Jaglan, Shikha Tewari 2023 Department of Periodontics, Post Graduate Institute of Dental Sciences, Rohtak, Haryana, India

Treatment Of Gingival Fenestration Using Mucoperiosteal Flap With Connective Tissue Graft: A Report Of Two Cases, Swati Jaglan, Shikha Tewari

Journal of Dentistry Indonesia

Fenestration term is derived from the Latin word ‘fenestra’ means ‘window’. Gingival fenestration is not found in routine while its actual occurrence is assumed to be higher. Additionally, if these mucogingival defects persist for a longer duration it may lead to adverse outcomes like compromised esthetics, hypersensitivity, plaque and calculus deposition, and susceptibility to dental caries. Present cases of gingival fenestration were successfully treated by using full-thickness flap elevation with connective tissue graft placement. Two cases were presented with the accumulation of plaque and calculus and having gingival fenestration to the respective sites. After phase 1 therapy, full thickness flap …


Management Of Tooth Hypersensitivity Under A Cantilever Fixed Partial Denture Using A Novel Low-Level Laser Therapy Protocol: A Case Report, Mohamed Fattouh, Manal Mohammed Aljuaid, Nada Ali AbdelAleem 2023 Department of Fixed Prosthodontics, Faculty of Dentistry, Cairo University, Cairo, Egypt; Department of Oral and Maxillofacial Surgery, Faculty of Dental Medicine, Umm Al-Qura University, Makkah, Saudi Arabia

Management Of Tooth Hypersensitivity Under A Cantilever Fixed Partial Denture Using A Novel Low-Level Laser Therapy Protocol: A Case Report, Mohamed Fattouh, Manal Mohammed Aljuaid, Nada Ali Abdelaleem

Journal of Dentistry Indonesia

Tooth hypersensitivity is a common clinical complaint after dental treatment.

Objective: This study presents a case report of the use of a diode laser for treating tooth hypersensitivity in a patient with a cantilever fixed partial denture abutment.

Case Report: A 23-year-old female patient presented to the Faculty of Dentistry, Umm Al-Qura University in Makkah, with the chief complaint of pain in a deeply carious maxillary right first premolar. The tooth was extracted, and a cantilever fixed partial denture was placed using the second premolar as an abutment. One year later, the patient experienced tooth hypersensitivity under the bridge. Low-level …


Research On The Influence Of Management Practices On Hospital Performance: An Empirical Study Based On Hospitals In Eastern China, Zhihua ZHANG 2023 Fordham University

Research On The Influence Of Management Practices On Hospital Performance: An Empirical Study Based On Hospitals In Eastern China, Zhihua Zhang

Fordham Dissertations and Theses

Since the beginning of the 21st century, a series of challenges have been confronting global health development, including significant factors affecting human health such as population aging, severe infectious diseases, and climate change. In particular, the COVID-19 that swept the globe in the past three years has posed a major comprehensive test to the global health governance system. As both the last line of defense for human health and the largest consumer of health resources, how the hospital can "improve quality and promote efficiency" based on limited resources is the core of the first priority. Previous studies have proven that …


The Impact Of Covid-19 And Associated Policy Responses On Global Food Security, Edward J. Balistreri, Felix Baquedano, John C. Beghin 2023 University of Nebraska-Lincoln

The Impact Of Covid-19 And Associated Policy Responses On Global Food Security, Edward J. Balistreri, Felix Baquedano, John C. Beghin

Department of Economics: Faculty Publications

We analyze the impact of the COVID-19 pandemic and associated policy responses on the global economy and food security in 80 low- and middle-income countries. We use a global economy-wide model with detailed disaggregation of agricultural and food sectors and develop a business-as-usual baseline for 2020 and 2021 called “But-for-COVID” (BfC). We then shock the model with aggregate income shocks derived from the IMF World Economic Outlook for 2020 and 2021. We impose total-factor productivity losses in key sectors as well as consumption decreases induced by social distancing. The resulting shocks in prices and incomes from the CGE model simulations …


Association Between Low Health Literacy And Adverse Health Behaviors In North Carolina, 2016, Manan Roy, Adam Hege, Erin D. Bouldin 2023 Appalachian State University

Association Between Low Health Literacy And Adverse Health Behaviors In North Carolina, 2016, Manan Roy, Adam Hege, Erin D. Bouldin

Journal of Appalachian Health

Introduction: Health literacy (HL) is an urgent public health challenge facing the U.S. HL is a critical factor in health inequities and exacerbates underlying social determinants of health.

Purpose: This study assesses the association between low HL (LHL) and adverse health behaviors, which contribute to poor health.

Methods: Researchers used North Carolina’s 2016 Behavioral Risk Factor Surveillance System data, namely, the Health Literacy optional module which asks respondents to rate how difficult it is for them to get health-related advice or to understand medical information (verbal or written). Health behaviors analyzed were excessive alcohol consumption, lack of adequate exercise and …


Effects Of The Raising The Minimum Legal Purchasing Age For Tobacco On Cigarette, Cocaine And Inhalant Consumption, Ahmed Adil 2023 CUNY Hunter College

Effects Of The Raising The Minimum Legal Purchasing Age For Tobacco On Cigarette, Cocaine And Inhalant Consumption, Ahmed Adil

Theses and Dissertations

Over the past few years, several states have passed laws that increase the minimum legal purchasing age (MLPA) for tobacco from 18 to 21 years. This study examines the impact of statewide MLPA laws on youth tobacco consumption. Using data from the 2009-2019 Youth Risky Behavior Surveys (YRBS) and a difference-in-differences approach, I find that the enactment of MLPA laws is associated with a decrease in tobacco usage among adolescents. I also find that MLPA laws have important spillover effects to other youth risky behaviors. MLPA law adoption is associated with a reduction in cocaine use and inhalant abuse.


Food As A Vector For Change: Lessons From The Third Sector On Improving Livelihoods With Nutritional Knowledge In Medellín And Bogotá, Solomon Treister 2023 Colby College

Food As A Vector For Change: Lessons From The Third Sector On Improving Livelihoods With Nutritional Knowledge In Medellín And Bogotá, Solomon Treister

Honors Theses

In this thesis I argue that improving diet in communities depends on building nutritional knowledge. In examining the role of community level organizations, I look specifically at how knowledge is conveyed through agriculture and gastronomy. This project analyzes how civil society organizations work to reintegrate individuals into food systems, compelling consumers to take agency over their diets and pursue better livelihoods. The industrialization of food systems has fundamentally changed the way humans connect with food and diet. In Colombia, internal displacements and urban migration have accelerated a loss of connection with the land and food processes. At the same time, …


Three Essays On Health, Food, And Agricultural Economics, Saber Feizy 2023 University of Kentucky

Three Essays On Health, Food, And Agricultural Economics, Saber Feizy

Theses and Dissertations--Agricultural Economics

This dissertation comprises three distinct but interrelated projects that explore the intersection of agriculture, nutrition, and economics. The first project investigates the impact of Community Supported Agriculture (CSA) food programs on the health outcomes of its participants. Using fixed effects models and a matching algorithm, the study finds that while conventional fixed effects models indicate a significant effect of CSA participation on diet-related medical expenditures, our modified time-heterogenous fixed effects model did not find a meaningful effect. The results of the matching method are consistent with those of our modified model.

The second project examines racial disparities in the prevalence …


An Analysis On How Housing Status Influences The Gut-Brain-Axis For Populations In And Around The Skid Row Area Of Los Angeles, California, Mauricio Guzman 2023 Claremont Colleges

An Analysis On How Housing Status Influences The Gut-Brain-Axis For Populations In And Around The Skid Row Area Of Los Angeles, California, Mauricio Guzman

Pitzer Senior Theses

Over recent years, the “microbiota-gut-brain axis” (MGBA) has garnered significant attention in the scientific community. Specifically, perturbations of the MGBA via stress and dietary intake have been linked to a wide-range of diseases including gastrointestinal diseases, metabolic diseases, mood disorders, and cognitive diseases. However, most studies have been solely conducted on mice models and have yet to consider the more complex, intricate systems that impact the human body. In addition, researchers have yet to consider the populations who may be most susceptible to chronic stress and negative dietary outcomes. Drawing from the fields of medical sociology, non-invasive human biology, and …


Three Essays On Health And Environmental Economics: Applications Of Spatial Econometrics And Spatial Analysis, Mohammed Syedul Islam 2023 West Virginia University

Three Essays On Health And Environmental Economics: Applications Of Spatial Econometrics And Spatial Analysis, Mohammed Syedul Islam

Graduate Theses, Dissertations, and Problem Reports (ETD)

Spatial interaction and the locational structure between observations play key roles in the field of econometrics for both cross-sectional and panel data analysis. Compared to a non-spatial econometric model, a spatial model relaxes the assumption of independency in observations. This research applies spatial and non-spatial econometrics in three different fields of applied economics: (1) drinking water and air quality violations impacts on lung and bronchus cancer incidence in the contiguous United States (U.S.); (2) spillover effects of non-pharmaceutical interventions (NPIs) on COVID-19 cases across the contiguous U.S. counties; and (3) urbanization impacts on carbon dioxide (CO2) emissions in …


Redlining And Opioid Overdose Outcomes: Do Historical Housing Policies Still Impact Health Today?, Sahana Paravantavida 2023 Bucknell University

Redlining And Opioid Overdose Outcomes: Do Historical Housing Policies Still Impact Health Today?, Sahana Paravantavida

Honors Theses

This study examines the relationship between historical housing policies and current health outcomes, specifically the impact of redlining on opioid overdose rates. Using data collected from the state of New Jersey, neighborhoods with a history of redlining have higher rates of opioid overdose deaths. My findings suggest that historical housing policies, which systematically excluded certain populations from accessing affordable housing and resources, continue to impact health outcomes today.


The Expected Risks And Exacerbations Of Poverty, Mental Health Disorders, And Maternal Mortality From Abortion Bans: A Comparative Literature Analysis, Daniel J. Francisco 2023 Central Washington University

The Expected Risks And Exacerbations Of Poverty, Mental Health Disorders, And Maternal Mortality From Abortion Bans: A Comparative Literature Analysis, Daniel J. Francisco

All Master's Theses

Background. Early termination of a pregnancy (hereinafter referred to as an “abortion”) has been debated in the United States (U.S.) for decades, without much regard to the negative outcomes that forced pregnancies have for those assigned female at birth regarding poverty, mental health and maternal mortality. In 1973, access to safe abortions was protected so long that the procedure was done within the legal gestational period and/or was necessary for the health and safety of the patient (Blackmun, 1972). Unfortunately, in 2022, the Supreme Court took that protection away and made it legal for states to determine the reproductive rights …


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