Statistical Methodology Commons^™

Upper-Sided Ewma-Based Distribution-Specific Tolerance Limits, Owen Visser

UNF Graduate Theses and Dissertations

Tolerance limits are constructed from sample data to ascertain if a proportion of a process is within specification limits. There exists multiple methods of calculating the sample size requirements for tolerance limits under various assumptions. In this research, a distribution-specific algorithm that utilizes the exponentially weighted moving average technique (EWMA), first introduced by Sa and Razaila (2004), is reconstructed. The algorithm is used to calculate the required sample sizes for continuous construction of upper-sided tolerance limits. The sample sizes and intervals constructed from them are compared to three existing methods for various distributions. The distribution-specific algorithm was observed to reduce …

The Need To Incorporate Communities In Compartmental Models, Michael J. Kane, Owais Gilani

Faculty Journal Articles

Tian et al. provide a framework for assessing population- level interventions of disease outbreaks through the construction of counterfactuals in a large-scale, natural experiment assessing the efficacy of mild, but early interventions compared to delayed interventions. The technique is applied to the recent SARS-CoV-2 outbreak with the population of Shenzhen, China acting as the mild-but-early treatment group and a combination of several US counties resembling Shenzhen but enacting a delayed intervention acting as the control. To help further the development of this framework and identify an avenue for further enhancement, we focus on the use and potential limitations of compartmental …

Bayesian Experimental Design For Bayesian Hierarchical Models With Differential Equations For Ecological Applications, Rebecca Atanga

Theses and Dissertations

Ecologists are interested in the composition of species in various ecosystems. Studying population dynamics can assist environmental managers in making better decisions for the environment. Traditionally, the sampling of species has been recorded on a regular time frequency. However, sampling can be an expensive process due to financial and physical constraints. In some cases the environments are threatening, and ecologists prefer to limit their time collecting data in the field. Rather than convenience sampling, a statistical approach is introduced to improve data collection methods for ecologists by studying the dynamics associated with populations of interest. Population models including the logistic …

Changepoint Detection In Correlated Categorical Time Series, Mo Li

Theses and Dissertations

This dissertation develops two changepoint tests for serially correlated ordinal categorical time series.

A cumulative sum type test is devised to test for a single changepoint in a correlated categorical data sequence, which is constructed from a latent Gaussian process through clipping techniques. A sequential parameter estimation procedure is proposed to estimate the model parameters. The method is illustrated via simulations and applied to a real categorized rainfall time series from Albuquerque, New Mexico.

The second changepoint test is a likelihood ratio type test based on a marginalized transition model. This model permits likelihood inference and the serial dependence is …

Bayesian Semi-Supervised Keyphrase Extraction And Jackknife Empirical Likelihood For Assessing Heterogeneity In Meta-Analysis, Guanshen Wang

Statistical Science Theses and Dissertations

This dissertation investigates: (1) A Bayesian Semi-supervised Approach to Keyphrase Extraction with Only Positive and Unlabeled Data, (2) Jackknife Empirical Likelihood Confidence Intervals for Assessing Heterogeneity in Meta-analysis of Rare Binary Events.

In the big data era, people are blessed with a huge amount of information. However, the availability of information may also pose great challenges. One big challenge is how to extract useful yet succinct information in an automated fashion. As one of the first few efforts, keyphrase extraction methods summarize an article by identifying a list of keyphrases. Many existing keyphrase extraction methods focus on the unsupervised setting, …

Improved Statistical Methods For Time-Series And Lifetime Data, Xiaojie Zhu

Statistical Science Theses and Dissertations

In this dissertation, improved statistical methods for time-series and lifetime data are developed. First, an improved trend test for time series data is presented. Then, robust parametric estimation methods based on system lifetime data with known system signatures are developed.

In the first part of this dissertation, we consider a test for the monotonic trend in time series data proposed by Brillinger (1989). It has been shown that when there are highly correlated residuals or short record lengths, Brillinger’s test procedure tends to have significance level much higher than the nominal level. This could be related to the discrepancy between …

Multi-Level Small Area Estimation Based On Calibrated Hierarchical Likelihood Approach Through Bias Correction With Applications To Covid-19 Data, Nirosha Rathnayake

Theses & Dissertations

Small area estimation (SAE) has been widely used in a variety of applications to draw estimates in geographic domains represented as a metropolitan area, district, county, or state. The direct estimation methods provide accurate estimates when the sample size of study participants within each area unit is sufficiently large, but it might not always be realistic to have large sample sizes of study participants when considering small geographical regions. Meanwhile, high dimensional socio-ecological data exist at the community level, providing an opportunity for model-based estimation by incorporating rich auxiliary information at the individual and area levels. Thus, it is critical …

On Simes’S Second Conjecture: An Extended Single-Step Simes Test Procedure For Multiple Testing, Matthew G. Hudson

Dissertations

One of the major concerns with multiple tests of significance is controlling the family wise error rate. Various methods have been developed to ensure that the false positive rate be maintained at some prespecified level. One of the most well know being the Bonferroni procedure. Simes presented an improved Bonferroni procedure for testing the global hypothesis that is more powerful and less conservative, especially with positively correlated tests. While Simes’s procedure is more powerful, it does not allow for making inferences on the individual hypotheses. However, the Simes procedure has since become the foundation of many p-value based multiple testing …

Statistical Approaches Of Gene Set Analysis With Quantitative Trait Loci For High-Throughput Genomic Studies., Samarendra Das

Electronic Theses and Dissertations

Recently, gene set analysis has become the first choice for gaining insights into the underlying complex biology of diseases through high-throughput genomic studies, such as Microarrays, bulk RNA-Sequencing, single cell RNA-Sequencing, etc. It also reduces the complexity of statistical analysis and enhances the explanatory power of the obtained results. Further, the statistical structure and steps common to these approaches have not yet been comprehensively discussed, which limits their utility. Hence, a comprehensive overview of the available gene set analysis approaches used for different high-throughput genomic studies is provided. The analysis of gene sets is usually carried out based on …

Quantifying The Simultaneous Effect Of Socio-Economic Predictors And Build Environment On Spatial Crime Trends, Alfieri Daniel Ek

Graduate Theses and Dissertations

Proper allocation of law enforcement agencies falls under the umbrella of risk terrainmodeling (Caplan et al., 2011, 2015; Drawve, 2016) that primarily focuses on crime prediction and prevention by spatially aggregating response and predictor variables of interest. Although mental health incidents demand resource allocation from law enforcement agencies and the city, relatively less emphasis has been placed on building spatial models for mental health incidents events. Analyzing spatial mental health events in Little Rock, AR over 2015 to 2018, we found evidence of spatial heterogeneity via Moran’s I statistic. A spatial modeling framework is then built using generalized linear models, …

Development Of An Effect Size To Classify The Magnitude Of Dif In Dichotomous And Polytomous Items, James D. Weese

Graduate Theses and Dissertations

A standardized effect size for the SIBTEST/POLYSIBTEST procedure is proposed, allowing for Differential Item Functioning (DIF) to be classified with a single set of DIF heuristics regardless of whether data are dichotomous or polytomous. This proposed standardized effect size accounts for both variability in responses and whether participants are included in the SIBTEST/POLYSIBTEST calculations. First, a new set of unstandardized effect size heuristics are established for dichotomous data that are more aligned with Educational Testing Service (ETS) standards using two and three parameter logistic (2PL and 3PL) models. Second, a standardized effect size is proposed and compared to other DIF …

Exploring The Relationship Between Children’S Vocabulary And Their Understanding Of Cardinality: A Methodological Approach, Justin Slifer, Emily Carrigan, Kristin Walker, Marie Coppola

Honors Scholar Theses

Is there a relationship between vocabulary and children’s understanding of cardinality? Does the way in which we classify cardinality data as tested by the Give-a-Number task affect finding such a relationship? This thesis explored these questions using a methodological approach, by testing the relationship between children’s receptive vocabulary scores and Give-a-Number scores classified in two different ways, the traditional knower-level assessment, as well as by calculating the proportion of trials answered correctly. A significant correlation was found between participants’ receptive vocabulary scores and Give-a-Number scores using both manners of classification, independent of the children’s ages. The results were compared with …

Predicting Postoperative Delirium Risk For Intracranial Surgery: A Statistical Machine Learning Approach, Juliet Aygun, Alaina Bartfeld, Sahana Rayan

The Journal of Purdue Undergraduate Research

No abstract provided.

Statistical Methods For Resolving Intratumor Heterogeneity With Single-Cell Dna Sequencing, Alexander Davis

Dissertations and Theses (Open Access)

Tumor cells have heterogeneous genotypes, which drives progression and treatment resistance. Such genetic intratumor heterogeneity plays a role in the process of clonal evolution that underlies tumor progression and treatment resistance. Single-cell DNA sequencing is a promising experimental method for studying intratumor heterogeneity, but brings unique statistical challenges in interpreting the resulting data. Researchers lack methods to determine whether sufficiently many cells have been sampled from a tumor. In addition, there are no proven computational methods for determining the ploidy of a cell, a necessary step in the determination of copy number. In this work, software for calculating probabilities from …

Lectures On Mathematical Computing With Python, Jay Gopalakrishnan

PDXOpen: Open Educational Resources

This open resource is a collection of class activities for use in undergraduate courses aimed at teaching mathematical computing, and computational thinking in general, using the python programming language. It was developed for a second-year course (MTH 271) revamped for a new undergraduate program in data science at Portland State University. The activities are designed to guide students' use of python modules effectively for scientific computation, data analysis, and visualization.

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Statistical Methodology To Establish A Benchmark For Evaluating Antimicrobial Resistance Genes Through Real Time Pcr Assay, Enakshy Dutta

Department of Statistics: Dissertations, Theses, and Student Research

Novel diagnostic tests are usually compared with gold standard tests for evaluating diagnostic accuracy. For assessing antimicrobial resistance (AMR) to bovine respiratory disease (BRD) pathogens, phenotypic broth microdilution method is used as gold standard (GS). The objective of the thesis is to evaluate the optimal cycle threshold (Ct) generated by real-time polymerase chain reaction (rtPCR) to genes that confer resistance that will translate to the phenotypic classification of AMR. Data from two different methodologies are assessed to identify Ct that will discriminate between resistance (R) and susceptibility (S). First, the receiver operating characteristic (ROC) curve was used to determine the …

Improving The Quality And Design Of Retrospective Clinical Outcome Studies That Utilize Electronic Health Records, Oliwier Dziadkowiec, Jeffery Durbin, Vignesh Jayaraman Muralidharan, Megan Novak, Brendon Cornett

HCA Healthcare Journal of Medicine

Electronic health records (EHRs) are an excellent source for secondary data analysis. Studies based on EHR-derived data, if designed properly, can answer previously unanswerable clinical research questions. In this paper we will highlight the benefits of large retrospective studies from secondary sources such as EHRs, examine retrospective cohort and case-control study design challenges, as well as methodological and statistical adjustment that can be made to overcome some of the inherent design limitations, in order to increase the generalizability, validity and reliability of the results obtained from these studies.

Italian Sociologists: A Community Of Disconnected Groups, Aliakbar Akbaritabar, Vincent Traag, Alberto Caimo, Flaminio Squazzoni

Articles

Examining coauthorship networks is key to study scientific collaboration patterns and structural characteristics of scientific communities. Here, we studied coauthorship networks of sociologists in Italy, using temporal and multi-level quantitative analysis. By looking at publications indexed in Scopus, we detected research communities among Italian sociologists. We found that Italian sociologists are fractured in many disconnected groups. The giant connected component of the Italian sociology could be split into five main groups with a mixture of three main disciplinary topics: sociology of culture and communication (present in two groups), economic sociology (present in three groups) and general sociology (present in three …

Working Children On Java Island 2017, Yuniarti

International Programs

Children's wellbeing has currently become a global concern as many of them are engaged in the labor force. A small area estimation (SAE) technique, EBLUP under Fey Herriot model, is employed to reveal their number in regencies of Java Island. Statistics have been disaggregated by geographical location (urban/rural) and gender. These statistics are required by the government as the basis for policy making.

Models For Data Analysis In Accelerated Reliability Growth, Cesar Alexander Ruiz Torres

Graduate Theses and Dissertations

This work develops new methodologies for analyzing accelerated testing data in the context of a reliability growth program for a complex multi-component system. Each component has multiple failure modes and the growth program consists of multiple test-fix stages with corrective actions applied at the end of each stage. The first group of methods considers time-to-failure data and test covariates for predicting the final reliability of the system. The time-to-failure of each failure mode is assumed to follow a Weibull distribution with rate parameter proportional to an acceleration factor. Acceleration factors are specific to each failure mode and test covariates. We …