Efficient Development Of Density-Insensitive Near-Infrared Methods For In-Line Drug Content Monitoring In Continuous Powder Streams,
2024
Duquesne University
Efficient Development Of Density-Insensitive Near-Infrared Methods For In-Line Drug Content Monitoring In Continuous Powder Streams, Natasha L. Velez-Silva
Electronic Theses and Dissertations
A well-defined action plan to respond effectively to sudden changes in product demand is critical for preventing drug shortages within the pharmaceutical industry. An effective way to increase the output of a continuous manufacturing (CM) process is through flow rate adjustments. However, robust analytical methods must be in place to ensure consistent analytical performance across varying flow rates. Existing approaches for mitigating the physical effects of flow rate on Near-Infrared (NIR) measurements are often burdensome. Thus, efficient robust modeling strategies that reduce the current calibration burden and ensure model insensitivity to the physical variations in CM systems are needed. In …
Mean From Median Estimation In Longitudinal Meta-Analysis Of Quality Of Life In Radiation Oncology Patients,
2024
University of Nebraska Medical Center
Mean From Median Estimation In Longitudinal Meta-Analysis Of Quality Of Life In Radiation Oncology Patients, Harlan R. Sayles
Theses & Dissertations
Meta-analysis of longitudinal data, where some of the studies report results with means and standard errors while others use medians and ranges, is a complex analytical problem with several challenges which must be overcome. Existing methods for estimating means from medians and either ranges, interquartile ranges, or both have not previously been evaluated in a longitudinal setting. In this work, a simulation study was used to estimate mean bias, between studies variance bias, and coverage of confidence intervals in a longitudinal setting. A second simulation study estimated the variance of meta-analysis results from a given set of studies that may …
How Should China Respond To “Pan-Data Sovereignty” Competition Among China, U.S., And Eu—An Analysis Based On The Digital Stack Model?,
2024
School of Information Management, Wuhan University, Wuhan 430072, China
How Should China Respond To “Pan-Data Sovereignty” Competition Among China, U.S., And Eu—An Analysis Based On The Digital Stack Model?, Yan Liu, Congjing Ran
Bulletin of Chinese Academy of Sciences (Chinese Version)
Data sovereignty has become deeply intertwined with various economic and social development factors such as technology, trade, economy, culture, society, and politics, leading to a “Pan-Data Sovereignty” competition pattern in the digital space. Through the digital stack model, which examines digital technologies in a layered framework, we can more clearly assess the competitive capacities in“Pan-Data Sovereignty” of China, United States, and European Union. The analysis identifies a three-tiered global “Pan-Data Sovereignty” competition structure among China, U.S., and EU, with each entity holding distinct advantages across various layers of the digital stack. Intense future competition is anticipated in fields such as …
Racial And Ethnic Differences In Outcomes Of Neonates Born At Less Than 30 Weeks' Gestation, 2018-2022,
2024
University of South Carolina
Racial And Ethnic Differences In Outcomes Of Neonates Born At Less Than 30 Weeks' Gestation, 2018-2022, Nansi S. Boghossian, Marco Geraci, Erika M. Edwards, Jeffrey D. Horbar
Faculty Publications
Importance: Previous research has examined outcomes among very preterm newborns by the birthing parent's race and ethnicity, but knowledge about these trends during the COVID-19 pandemic is limited. Objective: To examine trends in outcomes among Black, Hispanic, and Asian preterm newborns compared with White preterm newborns. Design, Setting, and Participants: This cohort study (2018-2022) took place at 774 neonatal intensive care units in the Vermont Oxford Network. Participants were newborns born at 22 to 29 weeks' gestation. Exposure: Race and ethnicity. Main Outcomes and Measures: The primary outcomes were mortality and complications, including respiratory distress syndrome, necrotizing enterocolitis (NEC), early-onset …
Method For Measuring The Rate Of Improvement In Survival Times Of Cancer Patients,
2024
University of Arkansas Little Rock
Method For Measuring The Rate Of Improvement In Survival Times Of Cancer Patients, Thobani Chaduka
Theses and Dissertations
In clinical settings, technological advancements have facilitated health care improvements in data analytics, artificial intelligence, telemedicine, health information systems, etc. This has furthered our understanding of cancer biology and treatment mechanisms. In this study, we aim to understand whether Moore’s law-like models may derive from historical cancer survival data, and how they can predict survival statistics for newly diagnosed cancer patients. Historically these predictions have previously been done with the diagnosis year as the independent variable and the survival as a dependent variable. In this study we use death year data as an independent variable and from that, we derive …
Optimization Of Construction Scheme Of Ultra‑Large Special‑Shaped Foundation Pit Adjacent To Existing Station And Temporary Steel Bridge,
2024
China Railway Southern Investment Group Co ., Ltd., Shenzhen , Guangdong 518060 , China
Optimization Of Construction Scheme Of Ultra‑Large Special‑Shaped Foundation Pit Adjacent To Existing Station And Temporary Steel Bridge, Chen Dengwei
Journal of China & Foreign Highway
With the intensifying development density of urban underground space in China，the impact of ultra-large foundation pit construction on the normal operation of adjacent structures cannot be ignored.Relying on the Huangmugang Comprehensive Transportation Hub Project in Shenzhen，this paper studied the deformation of the envelope structure and soil caused by the excavation of the ultra-large special-shaped foundation pit，as well as the structural response of the deformation of the adjacent existing station and the temporary steel bridge.The paper optimized the construction scheme of the special-shaped foundation pit excavation.The results show that the deformation trend of the envelope structure on the north and south …
Comparison Analysis Of Different Settlement Prediction Models Under Small Post‑ Constructio N Load On Soft Foundation,
2024
School of Traffic & Transportation Engineering , Changsha University of Science & Technology , Changsha , Hunan 410114 ,China
Comparison Analysis Of Different Settlement Prediction Models Under Small Post‑ Constructio N Load On Soft Foundation, Han S Hanpeng, Fu Wei, Zhang Junhui, Lin Chen
Journal of China & Foreign Highway
Settlement deformatio n is a key conc ern in soft foundation construction.Since there is still a small load applied after the filling of soft foundation in the actual project,based on the settlement monitoring data of the high-fill section of Zhaoyang West Ring Expressway in Zhaotong City,Yunnan Province,three settlement prediction methods,namely the hyperbolic method,the three-point method,and the Hoshino method,were used to predict,compare,and analyze the settlement of the fill foundation,and the fitting characteristics of each model were summarized.By comparing the fitting curves and the actual settlement curves,it was found that the loading on the roadbed will cause large errors in the prediction …
Experimental Study On Deformation Characteristics Of High Liquid Limit Soil Considering The Effect Of Temperature,
2024
Hainan Transportation Engineering Construction Bureau , Haikou , Hainan 570208 , China
Experimental Study On Deformation Characteristics Of High Liquid Limit Soil Considering The Effect Of Temperature, Li Bangwu, Shen Xuning, Zhang Rui, Chen Yanrong
Journal of China & Foreign Highway
In order to study the influence of temperature on the absorbed bound water and deformation characteristics of high liquid limit soil，the high liquid limit soil in Hunan and Hainan provinces were selected for test.The influence of temperature on the content of bound water was measured by a temperature-controlled water bath volumetric flask test.The consolidation test was carried out on the samples with a one-dimensional temperature-controlled consolidometer，and the variation law of high liquid limit soil deformation affected by temperature was analyzed under the modified pore ratio considering the bound water content.The results show that the absorbed bound water in the high …
Research Progress Of Rubber‑Modified Asphalt By Wet Process,
2024
School of Traffic & Transportation Engineering , Changsha University of Science & Technology , Changsha , Hunan 410114 , China ;National Engineering Research Center of Road Maintenance Technologies , Changsha , Hunan 410114 , China ;National Key Laboratory of Green and Long-Life Road Engineering in Extreme Environment , Changsha , Hunan 410114 , China
Research Progress Of Rubber‑Modified Asphalt By Wet Process, Ge Dongdong, Jiang Xiangyang, Lyu Songtao, Zhang Honggang, Song Xiaojin
Journal of China & Foreign Highway
The application of waste tires in asphalt pavements can not only effectively reduce resource consumption but also significantly reduce environmental pollution.Crumb rubber could be obtained by processing waste tires and used as a modifier by mixing with asphalt through the wet process to improve the performance of asphalt.This paper reviewed the research progress of rubber-modified asphalt by wet process and discussed its preparation process，influencing factors of performance，and modification mechanism.By reviewing the relevant studies，the critical conditions in the preparation process and their effects on storage stability were summarized.Furthermore，the effects of rubber dosage，particle size，matrix asphalt type，and preparation parameters on the physical and …
Friction‑ 1d Transformer ： A 1d Vision Transformer Hybrid Model For Skid Resistance Prediction On Asphalt Pavements,
2024
Sichuan Chengmian Cangba Expressway Co ., Ltd., Chengdu , Sichuan 618206 , China
Friction‑ 1d Transformer ： A 1d Vision Transformer Hybrid Model For Skid Resistance Prediction On Asphalt Pavements, Pei Feifei, Nie Zilong, Xu G Uomin, Zhan You, Gong Xianqi, Ai Changfa, Deng Yuan, Ji Zhengyun, Wang Shifa
Journal of China & Foreign Highway
The friction performance of road surfaces is an important indicator of highway safety，which is closely related to road texture.In this paper，a set of three-dimensional denoising methods for road texture data with different noise levels was proposed，which could effectively remove noise while preserving local texture features.In addition，a skid resistance prediction model named Friction- 1D Transformer was developed based on the design concept of Vision Transformer （VIT） for skid resistance evaluation of asphalt pavements.Unlike traditional convolutional neural networks，the Friction- 1D Transformer utilized positional encoding structures and multi-head attention mechanisms to extract global features from one-dimensional （1D） texture signals along the direction of …
Skid Resistance Detection Technology Of Highway Pavement Based On Tie‑Pavement Coupling Noise,
2024
China Merchants Chongqing Communications Technology Research & Design Institute Co .,Ltd., Chongqing 400067 , China
Skid Resistance Detection Technology Of Highway Pavement Based On Tie‑Pavement Coupling Noise, Ye Wei, Chen Fei, Hu Xiaoyang, Xu Zhengwei, Li Liguo
Journal of China & Foreign Highway
In order to improve the skid resistance detection technology of highway pavement，this paper summarized the advantages and disadvantages of the traditional pavement noise measurement methods，adopted the vehicle-following method to collect the tie-pavement coupling noise，and optimized the specific positional parameters of the microphone.The speed correction of the equivalent continuous A-weighted sound level was realized through the fitting of driving speed and equivalent continuous A-weighted sound level.The characteristic signal of the tie-pavement coupling noise was extracted by the principal component analysis method，and it can effectively suppress interference signals such as traffic noise，wind noise，and engine noise.The envelope noise energy （ENE） was obtained by …
Mechanical Properties Of Alkali‑Activated Slag‑Fly Ash Geopolymers,
2024
School of Civil Engineering , Changsha University of Science & Technology , Changsha , Hunan 410114 , China
Mechanical Properties Of Alkali‑Activated Slag‑Fly Ash Geopolymers, Liu Yang, Wang Jizhao, Lu Naiwei, Wang Bowen
Journal of China & Foreign Highway
In order to respond to the national strategy of energy saving and emission reduction and improve the comprehensive utilization rate of industrial waste，the influence of slag content，alkali equivalent，sodium silicate modulus，and water-cement ratio on the compressive strength of slag-fly ash geopolymers was investigated by single variable and orthogonal experiment method.The compressive strength of geopolymers was analyzed by combining XRD，SEM，and porosity.The results show that the gel formation is promoted with the increase in slag content，and the structure of geopolymers is more compact，which is conducive to the development of strength.After 28 days of standard curing，the influence of various factors on the compressive strength …
Mechanical Properties Of Geopolymer‑Stabilized Recycled Aggregates From Construction Solid Wastes,
2024
China Road & Bridge Corporation ，Beijing 100001 ,China
Mechanical Properties Of Geopolymer‑Stabilized Recycled Aggregates From Construction Solid Wastes, Yuan Kaixin, He Yongjian, Zhang Laijun, Li Hai, Xu Gewei
Journal of China & Foreign Highway
In order to solve the problem of a sharp increase in construction solid wastes and insufficient utilization rate，this paper took slag-fly ash-based geopolymer as an inorganic binder，replaced natural gravels with recycled aggregates from construction solid wastes，and set urban road base layer as the target scene to study the mechanical properties of geopolymer-stabilized recycled aggregates at different contents.The results show that with the increase in geopolymer content，the maximum dry density of the mixture increases.The optimum moisture content increases.The unconfined compressive strength of the mixture increases with the increase in geopolymer content and curing age and decreases with the increase in recycled …
Experimental Investigation On Shrinkage Effect Of Ultra‑High Performance Concrete Under Steam Curing,
2024
Foshan Jianying Development Group Co ., Ltd., Foshan ,Guangdong 528000 , China
Experimental Investigation On Shrinkage Effect Of Ultra‑High Performance Concrete Under Steam Curing, Li Bing, Yang Tengyu, Fang Changle, Luo Zirun, Li Chuanxi, Tan Ke
Journal of China & Foreign Highway
Determining the free shrinkage of U HPC is an important basis for analyzing the shrinkage effect of steel UHPC composite bridge deck.Therefore，based on the UHPC materials to be used in a project，three batches of UHPC free shrinkage specimens were made，and three specimens were made in each batch.By testing the strain and temperature of specimens during curing，the free shrinkage strain-age curve and temperature-age curve of UHPC were obtained.The development and variation law of UHPC shrinkage strain are discussed.Based on the experimental results，the equivalent time is introduced on the basis of Arrhenius empirical formula，and a modified model of free shrinkage is proposed.Finally，based …
Comparative Experimental Study On Deformation Characteristics Of High Liquid Limit Soil Under Different Dry And Wet States,
2024
School of Traffic & Transportation Engineering , Changsha University of Science & Technology , Changsha ，Hunan 410114 , China
Comparative Experimental Study On Deformation Characteristics Of High Liquid Limit Soil Under Different Dry And Wet States, Qin Lingwei, Zhang Rui, Li Lu, Xiao Yupeng
Journal of China & Foreign Highway
In order to further reveal the internal mechanism of the influence of solid-like bound water on the deformation characteristics of high liquid limit soil，the difference in the influence of different bound water contents on the deformation of soil samples was analyzed through the comparison of dry and wet sides.Four types of high liquid limit soil with different water contents at the same dry density were used，and a low liquid limit soil was used as a comparison sample to carry out a deformation test.The volumetric flask method was used to test the content of adsorbed bound water in each test soil …
Influence Of Loading Methods On Compression Modulus Of Red Sandstone Soil Solidified With Biological Enzyme And Cement,
2024
Hunan Hengyong Expressway Construction and Development Co ., Ltd., Yongzhou , Hunan 426100 , China
Influence Of Loading Methods On Compression Modulus Of Red Sandstone Soil Solidified With Biological Enzyme And Cement, He Liang, Zhang Haixiang, Guan H Ongxin, Li Huili, Yang Hairong, Liu Hongfu
Journal of China & Foreign Highway
There are various methods to test the modulus of cement-stabilized mixtures.The stiffness performance of cement-stabilized materials will be affected after adding biological enzymes.In order to systematically analyze the influence of loading conditions on the compression modulus of the red sandstone soil solidified with biological enzyme and cement，compressive modulus tests were conducted on the red sandstone soil solidified with biological enzyme and cement by using three static modulus test methods including monotonic loading method of middle section，stepwise loading and unloading method of top surface，and stepwise loading and unloading method of middle section，as well as dynamic modulus method of top surface and …
Mechanical And Vegetative Performance Of Bamboo Fiber‑Reinforced Eco‑Concrete With Recycled Aggregate,
2024
School of Municipal and Ecological Engineering , Shanghai Urban Construction Vocational College , Shanghai 201415，China;School of Naval Architecture and Maritime , Zhejiang Ocean University , Zhoushan ，Zhejiang 316022，China
Mechanical And Vegetative Performance Of Bamboo Fiber‑Reinforced Eco‑Concrete With Recycled Aggregate, Li Tao, Deng Bofan, He Maolin, Liu Ting, Chen Houde
Journal of China & Foreign Highway
In response to the current common urban construction waste disposal issue，this study utilized processed recycled construction waste aggregate and bamboo waste materials to produce bamboo fiber-reinforced eco-concrete with recycled aggregate.By adjusting the dosage of bamboo fiber，the effects of the dosage of bamboo fiber on the mechanical and vegetative performance of the concrete were systematically analyzed by means of orthogonal tests and verification methods.The test results indicate that bamboo fiber enhances the toughness of eco-concrete significantly.Particularly，when the dosage of bamboo fiber exceeds 3.0 kg/m3，there is a significant enhancement in the tensile performance of the eco-concrete with recycled aggregate.Due to the spatial …
Effect Of Corn Stover Oil On Rheological Properties Of Aged Asphalt And Its Regeneration Effect,
2024
College of Civil Engineering , Northeast Forestry University ，Harbin ,Heilongjiang 150040 , China
Effect Of Corn Stover Oil On Rheological Properties Of Aged Asphalt And Its Regeneration Effect, Cheng Peifeng, Bai Yue, Li Yiming, Zhang Zhanming
Journal of China & Foreign Highway
Corn stover oil，as a kind of bio-oil，is low-carbon and renewable.At the same time，it may restore the performance of aged asphalt.In order to further promote the application of corn stover oil in road engineering，this study explored the effect of corn stover oil as a kind of regeneration agent on the rheological properties of aged asphalt through laboratory experiments and analyzed the regeneration effect.On this basis，the regeneration mechanism of corn stover oil regeneration agent was revealed by using an infrared spectroscopy test and gel permeation chromatography test.The results show that the addition of corn stover oil changes the proportion of aged asphalt …
Optimization Of Mix Proportion For New Jersey Precast Concrete Safety Barriers And Performance Tests Under Integral Concrete Vibrating,
2024
Guangxi Xinxiang Expressway Co ., Ltd., Nanning , Guangxi 530004 , China
Optimization Of Mix Proportion For New Jersey Precast Concrete Safety Barriers And Performance Tests Under Integral Concrete Vibrating, Chen Lin, Li Beian, Li Yuanrui, Zhao Zixiang
Journal of China & Foreign Highway
New Jersey safety barriers are the most commonly used form of guardrails in highway median separators due to their excellent safety protection.In response to the cost reduction and quality improvement，efficient and rapid preparation process，and quality issues of New Jersey precast concrete safety barriers，this article adopted the automation production process of New Jersey precast safety barriers，optimized concrete mix proportion for precast safety barriers，and studied their performance.The experimental results show that in the designed C 30 concrete，the compressive strength of the concrete mixed with 15% fly ash reaches 39.2 MPa，and th e slump reaches 185 mm.The concrete performance meets the requirements of …
Curing Law And Road Performance Of Polyurethane Mixture,
2024
Sichuan Transportation Construction Group Co ., Ltd., Chengdu ,Sichuan 610000 , China
Curing Law And Road Performance Of Polyurethane Mixture, Sun Shengkai, Zheng Mao, Tang Xiong, Liu Li, Zhong Shengran, Si Te
Journal of China & Foreign Highway
Polyurethane mixture is composed of polyurethane binder，rubber particles，and stones.Compared with ordinary asphalt mixture，it has the characteristics of a higher content of rubber particles and large void ratios.This article first tested the viscosity-time curve and viscosity-temperature curve of one-component polyurethane and determined the compaction temperature of the polyurethane mixture.Based on the rutting test，three-point bending test，water immersion Marshall test，freeze-thaw splitting test，and pendulum friction test，the road performance of the polyurethane mixture under different replacement amounts of rubber particles was tested.The research results show that the mixing temperature of PU- 1 polyurethane mixture can be basically controlled between 73 ℃ and 81 ℃，and it …
