Cohomology Operations On Random Spaces,
2016
Wayne State University
Cohomology Operations On Random Spaces, Matthew John Zabka
Wayne State University Dissertations
Topology has recently received more attention from statisticians as some its tools have been applied to understanding the shape of data. In particular, a data set can generate a topological space, and this space’s topological structure can give us insight into some properties of the data. This framework has made it necessary to study random spaces generated by data. For example, without an understanding of the probabilistic properties of random spaces, one cannot conclude with any degree of confidence what the tools of topology tell us about a data set. While some results are known about the cohomological structure of …
Salvage Brachytherapy For Biochemically Recurrent Prostate Cancer Following Primary Brachytherapy,
2016
University of Kentucky
Salvage Brachytherapy For Biochemically Recurrent Prostate Cancer Following Primary Brachytherapy, John M. Lacy, William A. Wilson, Raevti Bole, Li Chen, Ali S. Meigooni, Randall G. Rowland, William H. St. Clair
Urology Faculty Publications
Purpose. In this study, we evaluated our experience with salvage brachytherapy after discovery of biochemical recurrence after a prior brachytherapy procedure. Methods and Materials. From 2001 through 2012 twenty-one patients treated by brachytherapy within University of Kentucky or from outside centers developed biochemical failure and had no evidence of metastases. Computed tomography (CT) scans were evaluated; patients who had an underseeded portion of their prostate were considered for reimplantation. Results. The majority of the patients in this study (61.9%) were low risk and median presalvage PSA was 3.49 (range 17.41–1.68). Mean follow-up was 61 months. At last follow-up after reseeding, …
Causal Inference In Observational Studies With Clustered Data,
2016
University at Albany, State University of New York
Causal Inference In Observational Studies With Clustered Data, Meng Wu
Legacy Theses & Dissertations (2009 - 2024)
In this thesis, we study causal inference in observational studies with clustered data.
Estimating Survival Distributions, Important Covariates And Time-Varying Associations,
2016
University at Albany, State University of New York
Estimating Survival Distributions, Important Covariates And Time-Varying Associations, Yan Wu
Legacy Theses & Dissertations (2009 - 2024)
There are three papers each on a different topic in this thesis. The first paper proposes a new objective methodology to estimate any subject specific survival distribution with potential time-varying effect by adjusting approximated polynomial censored survival function with estimated censoring distribution under three different assumptions: uniform censoring, independent censoring and non-informative censoring. The coefficients of the polynomial censored survival function and underlying censoring probability are estimated at each event or censoring time point across the study time frame, which naturally accommodates potential non-proportional hazards along with time-varying effect. An extensive simulation study indicates that the proposed methods usually perform …
On Variable Bandwidth Kernel Density And Regression Estimation,
2016
University of Mississippi
On Variable Bandwidth Kernel Density And Regression Estimation, Janet Nakarmi
Electronic Theses and Dissertations
We study the ideal variable bandwidth kernel density estimator introduced by McKay (1993) and the plug-in practical version of the variable bandwidth kernel density estimator with two sequences of bandwidths as in Ginè and Sang (2013).We estimate the variance of the variable bandwidth kernel density estimator. Based on the exact formula of the bias and the variance of the variable bandwidth kernel density estimator, we develop the optimal bandwidth selection of the true variable bandwidth kernel density estimator. Furthermore, we present the central limit theorem of the true variable bandwidth kernel density estimator. We also propose a new variable bandwidth …
Collective Action And Decision Making: An Analysis Of Economic Modeling And Environmental Free-Riding,
2016
DePauw University
Collective Action And Decision Making: An Analysis Of Economic Modeling And Environmental Free-Riding, Thomas Miller 16
Honor Scholar Theses
No abstract provided.
Consensus Regularized Selection Based Prediction,
2016
Wayne State University
Consensus Regularized Selection Based Prediction, Ping Wang
Wayne State University Theses
Integrating regularization methods within a regression framework has become a popular choice for researchers to build predictive models with lower variance and better generalization. Regularizers also aid in building interpretable models with high-dimensional data which makes them very appealing. Regularizers in general are unique in nature as they cater to data specific features such as correlation, structured sparsity, and temporal smoothness. The problem of obtaining a consensus among such diverse regularizers is extremely important in order to determine the optimal regularizer for the model. This is called the consensus regularization problem which has not received much attention in the literature, …
An Ensemble Model Of Qsar Tools For Regulatory Risk Assessment,
2016
Marquette University
An Ensemble Model Of Qsar Tools For Regulatory Risk Assessment, Prachi Pradeep, Richard J. Povinelli, Shannon White, Stephen Merrill
Mathematics, Statistics and Computer Science Faculty Research and Publications
Quantitative structure activity relationships (QSARs) are theoretical models that relate a quantitative measure of chemical structure to a physical property or a biological effect. QSAR predictions can be used for chemical risk assessment for protection of human and environmental health, which makes them interesting to regulators, especially in the absence of experimental data. For compatibility with regulatory use, QSAR models should be transparent, reproducible and optimized to minimize the number of false negatives. In silico QSAR tools are gaining wide acceptance as a faster alternative to otherwise time-consuming clinical and animal testing methods. However, different QSAR tools often make conflicting …
Solving Set Cover With Pairs Problem Using Quantum Annealing,
2016
Purdue University
Solving Set Cover With Pairs Problem Using Quantum Annealing, Yudong Cao, Shuxian Jiang, Debbie Perouli, Sabre Kais
Mathematics, Statistics and Computer Science Faculty Research and Publications
Here we consider using quantum annealing to solve Set Cover with Pairs (SCP), an NP-hard combinatorial optimization problem that plays an important role in networking, computational biology, and biochemistry. We show an explicit construction of Ising Hamiltonians whose ground states encode the solution of SCP instances. We numerically simulate the time-dependent Schrödinger equation in order to test the performance of quantum annealing for random instances and compare with that of simulated annealing. We also discuss explicit embedding strategies for realizing our Hamiltonian construction on the D-wave type restricted Ising Hamiltonian based on Chimera graphs. Our embedding on the Chimera graph …
A Generalized Gamma-Weibull Distribution: Model, Properties And Applications,
2016
Yazd University
A Generalized Gamma-Weibull Distribution: Model, Properties And Applications, R. S. Meshkat, H. Torabi, Gholamhossein G. Hamedani
Mathematics, Statistics and Computer Science Faculty Research and Publications
We prepare a new method to generate family of distributions. Then, a family of univariate distributions generated by the Gamma random variable is defined. The generalized gamma-Weibull (GGW) distribution is studied as a special case of this family. Certain mathematical properties of moments are provided. To estimate the model parameters, the maximum likelihood estimators and the asymptotic distribution of the estimators are discussed. Certain characterizations of GGW distribution are presented. Finally, the usefulness of the new distribution, as well as its effectiveness in comparison with other distributions, are shown via an application of a real data set.
Collective Estimation Of Multiple Bivariate Density Functions With Application To Angular-Sampling-Based Protein Loop Modeling,
2016
Marquette University
Collective Estimation Of Multiple Bivariate Density Functions With Application To Angular-Sampling-Based Protein Loop Modeling, Mehdi Maadooliat, Lan Zhou, Seyed Morteza Najibi, Xin Gao, Jianhua Z. Huang
Mathematics, Statistics and Computer Science Faculty Research and Publications
This article develops a method for simultaneous estimation of density functions for a collection of populations of protein backbone angle pairs using a data-driven, shared basis that is constructed by bivariate spline functions defined on a triangulation of the bivariate domain. The circular nature of angular data is taken into account by imposing appropriate smoothness constraints across boundaries of the triangles. Maximum penalized likelihood is used to fit the model and an alternating blockwise Newton-type algorithm is developed for computation. A simulation study shows that the collective estimation approach is statistically more efficient than estimating the densities individually. The proposed …
A Hybrid Segmentation And D-Bar Method For Electrical Impedance Tomography,
2016
Marquette University
A Hybrid Segmentation And D-Bar Method For Electrical Impedance Tomography, Sarah J. Hamilton, J. M. Reyes, Samuli Siltanen, X. Zhang
Mathematics, Statistics and Computer Science Faculty Research and Publications
The regularized D-bar method for electrical impedance tomography (EIT) provides a rigorous mathematical approach for solving the full nonlinear inverse problem directly, i.e., without iterations. It is based on a low-pass filtering in the (nonlinear) frequency domain. However, the resulting D-bar reconstructions are inherently smoothed, leading to a loss of edge distinction. In this paper, a novel method that combines a D-bar approach with the edge-preserving nature of total variation (TV) regularization is presented. The method also includes a data-driven contrast adjustment technique guided by the key functions (CGO solutions) of the D-bar method. The new TV-enhanced D-bar …
Pain Level Detection From Facial Image Captured By Smartphone,
2016
Marquette University
Pain Level Detection From Facial Image Captured By Smartphone, Md Kamrul Hasan, Golam Mushih Tanimul Ahsan, Sheikh Iqbal Ahamed, Rechard Love, Reza Salim
Mathematics, Statistics and Computer Science Faculty Research and Publications
Accurate symptom of cancer patient in regular basis is highly concern to the medical service provider for clinical decision making such as adjustment of medication. Since patients have limitations to provide self-reported symptoms, we have investigated how mobile phone application can play the vital role to help the patients in this case. We have used facial images captured by smart phone to detect pain level accurately. In this pain detection process, existing algorithms and infrastructure are used for cancer patients to make cost low and user-friendly. The pain management solution is the first mobile-based study as far as we found …
Remarks On A Paper Of Ahmad, Ahmad And Ahmed,
2016
Marquette University
Remarks On A Paper Of Ahmad, Ahmad And Ahmed, Gholamhossein G. Hamedani
Mathematics, Statistics and Computer Science Faculty Research and Publications
Ahmad et al. (2015) consider a Transmuted Kumaraswamy distribution and study certain properties of their distribution. In the title of their paper they mention characterization of this distribution, but no characterization are presented in their paper. In the present short note, we establish certain characterizations of the Transmuted Kumaraswamy distribution in three directions.
The Transmuted Weibull-Pareto Distribution,
2016
Benha University
The Transmuted Weibull-Pareto Distribution, Ahmed Z. Afify, Haitham M. Yousof, Nadeem Shafique Butt, Gholamhossein G. Hamedani
Mathematics, Statistics and Computer Science Faculty Research and Publications
A new generalization of the Weibull-Pareto distribution called the transmuted Weibull-Pareto distribution is proposed and studied. Various mathematical properties of this distribution including ordinary and incomplete moments, quantile and generating functions, Bonferroni and Lorenz curves and order statistics are derived. The method of maximum likelihood is used for estimating the model parameters. The flexibility of the new lifetime model is illustrated by means of an application to a real data set.
Almost Perfect Restriction Semigroups,
2016
Marquette University
Almost Perfect Restriction Semigroups, Peter R. Jones
Mathematics, Statistics and Computer Science Faculty Research and Publications
We call a restriction semigroup almost perfect if it is proper and the least congruence that identifies all its projections is perfect. We show that any such semigroup is isomorphic to a ‘W -product’ W(T,Y)W(T,Y), where T is a monoid, Y is a semilattice and there is a homomorphism from T into the inverse semigroup TIYTIY of isomorphisms between ideals of Y. Conversely, all such W-products are almost perfect. Since we also show that every restriction semigroup has an easily computed cover of this type, the combination yields a ‘McAlister-type’ theorem for all restriction semigroups. …
On Six-Parameter Fréchet Distribution: Properties And Applications,
2016
Benha University
On Six-Parameter Fréchet Distribution: Properties And Applications, Haitham M. Yousof, Ahmed Z. Afify, Abd El Hadi N. Ebraheim, Gholamhossein G. Hamedani, Nadeem Shafique Butt
Mathematics, Statistics and Computer Science Faculty Research and Publications
This paper introduces a new generalization of the transmuted Marshall-Olkin Fréchet distribution of Afify et al. (2015), using Kumaraswamy generalized family. The new model is referred to as Kumaraswamy transmuted Marshall-Olkin Fréchet distribution. This model contains sixty two sub-models as special cases such as the Kumaraswamy transmuted Fréchet, Kumaraswamy transmuted Marshall-Olkin, generalized inverse Weibull and Kumaraswamy Gumbel type II distributions, among others. Various mathematical properties of the proposed distribution including closed forms for ordinary and incomplete moments, quantile and generating functions and Rényi and η-entropies are derived. The unknown parameters of the new distribution are estimated using the maximum …
On The Double Chain Ladder For Reserve Estimation With Bootstrap Applications,
2016
Missouri University of Science and Technology
On The Double Chain Ladder For Reserve Estimation With Bootstrap Applications, Larissa Schoepf
Masters Theses
"To avoid insolvency, insurance companies must have enough reserves to fulfill their present and future commitment-refer to in this thesis as outstanding claims towards policyholders. This entails having an accurate and reliable estimate of funds necessary to cover those claims as they are presented. One of the major techniques used by practitioners and researchers is the single chain ladder method. However, though most popular and widely used, the method does not offer a good understanding of the distributional properties of the way claims evolve. In a series of recent papers, researchers have focused on two potential components of outstanding claims, …
Unequal Edge Inclusion Probabilities In Link-Tracing Network Sampling With Implications For Respondent-Driven Sampling,
2016
Augsburg College
Unequal Edge Inclusion Probabilities In Link-Tracing Network Sampling With Implications For Respondent-Driven Sampling, Miles Q. Ott, Krista J. Gile
Statistical and Data Sciences: Faculty Publications
Respondent-Driven Sampling (RDS) is a widely adopted linktracing sampling design used to draw valid statistical inference from samples of populations for which there is no available sampling frame. RDS estimators rely upon the assumption that each edge (representing a relationship between two individuals) in the underlying network has an equal probability of being sampled. We show that this assumption is violated in even the simplest cases, and that RDS estimators are sensitive to the violation of this assumption.
A Multistep Approach To Single Nucleotide Polymorphism-Set Analysis: An Evaluation Of Power And Type I Error Of Gene-Based Tests Of Association After Pathway-Based Association Tests,
2016
University of Connecticut
A Multistep Approach To Single Nucleotide Polymorphism-Set Analysis: An Evaluation Of Power And Type I Error Of Gene-Based Tests Of Association After Pathway-Based Association Tests, Alessandra Valcarcel, Kelsey Grinde, Kaitlyn Cook, Alden Green, Nathan Tintle
Statistical and Data Sciences: Faculty Publications
The aggregation of functionally associated variants given a priori biological information can aid in the discovery of rare variants associated with complex diseases. Many methods exist that aggregate rare variants into a set and compute a single p value summarizing association between the set of rare variants and a phenotype of interest. These methods are often called gene-based, rare variant tests of association because the variants in the set are often all contained within the same gene. A reasonable extension of these approaches involves aggregating variants across an even larger set of variants (eg, all variants contained in genes within …
