Do Firms Respond To Peer Disclosures? Evidence From Clinical Trial Disclosures,
2021
HEC Paris
Do Firms Respond To Peer Disclosures? Evidence From Clinical Trial Disclosures, Vedran Capkun, Yun Lou, Clemens A. Otto, Yin Wang
Research Collection School Of Accountancy
We examine whether a firm’s decision to disclose non-financial proprietary information depends on peer disclosures of similar information. Using a sample of 5,035 unique clinical trials by U.S. pharmaceutical firms over the 2007-2014 period, we find that the firm is less likely to disclose its own clinical trial results if peers have published clinical trial results pertaining to the same medical condition. Conditional on disclosing clinical trial results, the firm is also less likely to disclose the trial results on time when peers have disclosed their clinical trial results. Our cross-sectional tests suggest that proprietary costs of disclosure play an …
The Forestecology R Package For Fitting And Assessing Neighborhood Models Of The Effect Of Interspecific Competition On The Growth Of Trees,
2021
Smith College
The Forestecology R Package For Fitting And Assessing Neighborhood Models Of The Effect Of Interspecific Competition On The Growth Of Trees, Albert Y. Kim, David N. Allen, Simon P. Couch
Statistical and Data Sciences: Faculty Publications
Neighborhood competition models are powerful tools to measure the effect of interspecific competition. Statistical methods to ease the application of these models are currently lacking. We present the forestecology package providing methods to (a) specify neighborhood competition models, (b) evaluate the effect of competitor species identity using permutation tests, and (cs) measure model performance using spatial cross-validation. Following Allen and Kim (PLoS One, 15, 2020, e0229930), we implement a Bayesian linear regression neighborhood competition model. We demonstrate the package's functionality using data from the Smithsonian Conservation Biology Institute's large forest dynamics plot, part of the ForestGEO global network of research …
Beluga Whale (Delphinapterus Leucas) Acoustic Foraging Behavior And Applications For Long Term Monitoring,
2021
University of Washington
Beluga Whale (Delphinapterus Leucas) Acoustic Foraging Behavior And Applications For Long Term Monitoring, Manuel Castellote, Aran Mooney, Russel Andrews, Stacy L. Deruiter
University Faculty Publications and Creative Works
Cook Inlet, Alaska, is home to an endangered and declining population of 279 belugas (Delphinapterus leucas). Recovery efforts highlight a paucity of basic ecological knowledge, impeding the correct assessment of threats and the development of recovery actions. In particular, information on diet and foraging habitat is very limited for this population. Passive acoustic monitoring has proven to be an efficient approach to monitor beluga distribution and seasonal occurrence. Identifying acoustic foraging behavior could help address the current gap in information on diet and foraging habitat. To address this conservation challenge, eight belugas from a comparative, healthy population in Bristol Bay, …
Effects Of Sesame Consumption On Inflammatory Biomarkers In Humans: A Systematic Review And Meta-Analysis Of Randomized Controlled Trials,
2021
University of South Carolina
Effects Of Sesame Consumption On Inflammatory Biomarkers In Humans: A Systematic Review And Meta-Analysis Of Randomized Controlled Trials, Shabnam Rafiee, Roghaye Faryabi, Mohammad Ali Zareian, Jessie Hawkins, Nitin Shivappa Mbbs, Mph, Ph.D., Laila Shirbeigi
Faculty Publications
Objectives. Existing evidence produces conflicting findings regarding the effect of sesame intake on inflammatory biomarkers; thisknowledge gap has yet to be met through systematic review and meta-analysis. )is meta-analysis of randomized, controlledclinical trials (RCTs) was conducted to evaluate the effects of sesame consumption on markers of inflammation in humans. Methods. PubMed, Scopus, and the Cochrane Database of Systematic Reviews were searched through August 2020 to identify relevant papers for inclusion. Using the random-effects model, data were evaluated as weighted mean differences (WMD) with 95% confidence intervals (CI). Cochrane’s Q and I-squared (I2) tests were used to …
Port Throughput Forecasting Using Arima And Ols Regression : Case Study : Gwangyang Port In Korea,
2021
World Maritime University
Port Throughput Forecasting Using Arima And Ols Regression : Case Study : Gwangyang Port In Korea, Shin Park
World Maritime University Dissertations
No abstract provided.
Online And Adjusted Human Activities Recognition With Statistical Learning,
2021
University of South Florida
Online And Adjusted Human Activities Recognition With Statistical Learning, Yanjia Zhang
USF Tampa Graduate Theses and Dissertations
Wearable human activity recognition (HAR) is a widely application system for our daily life. It hasbeen built in many devices, such as smartphone, smartwatch, activity tracker, and health monitor. Many researchers try to develop a system which requires less memory space and power, but has fast and accurate classification results. Moreover, the objective of adjusting the classifier by the system self is also a study direction. In the present study, we introduced the machine learning methods to both smartphone data and smartwatch data and an adjusted model with the continuous generating data. Further, we also proposed a new HAR system …
Shape-Based Classification Of Partially Observed Curves, With Applications To Anthropology,
2021
Loyola University Chicago
Shape-Based Classification Of Partially Observed Curves, With Applications To Anthropology, Gregory J. Matthews, Karthik Bharath, Sebastian Kurtek, Juliet K. Brophy, George K. Thiruvathukal, Ofer Harel
Computer Science: Faculty Publications and Other Works
We consider the problem of classifying curves when they are observed only partially on their parameter domains. We propose computational methods for (i) completion of partially observed curves; (ii) assessment of completion variability through a nonparametric multiple imputation procedure; (iii) development of nearest neighbor classifiers compatible with the completion techniques. Our contributions are founded on exploiting the geometric notion of shape of a curve, defined as those aspects of a curve that remain unchanged under translations, rotations and reparameterizations. Explicit incorporation of shape information into the computational methods plays the dual role of limiting the set of all possible completions …
A Comparison Of Bayesian Spatial Models For Hiv Mapping In South Africa,
2021
University of South Carolina - Columbia
A Comparison Of Bayesian Spatial Models For Hiv Mapping In South Africa, Kassahun Abere Ayalew, Samuel Manda, Bo Cai Ph.D.
Faculty Publications
Despite making significant progress in tackling its HIV epidemic, South Africa, with 7.7 million people living with HIV, still has the biggest HIV epidemic in the world. The Government, in collaboration with developmental partners and agencies, has been strengthening its responses to the HIV epidemic to better target the delivery of HIV care, treatment strategies and prevention services. Population-based household HIV surveys have, over time, contributed to the country’s efforts in monitoring and understanding the magnitude and heterogeneity of the HIV epidemic. Local-level monitoring of progress made against HIV and AIDS is increasingly needed for decision making. Previous studies have …
Facilitating Team-Based Data Science: Lessons Learned From The Dsc-Wav Project,
2021
University of Minnesota
Facilitating Team-Based Data Science: Lessons Learned From The Dsc-Wav Project, Chelsey Legacy, Andrew Zieffler, Benjamin S. Baumer, Valerie Barr, Nicholas J. Horton
Statistical and Data Sciences: Faculty Publications
While coursework provides undergraduate data science students with some relevant analytic skills, many are not given the rich experiences with data and computing they need to be successful in the workplace. Additionally, students often have limited exposure to team-based data science and the principles and tools of collaboration that are encountered outside of school. In this paper, we describe the DSC-WAV program, an NSF-funded data science workforce development project in which teams of undergraduate sophomores and juniors work with a local non-profit organization on a data-focused problem. To help students develop a sense of agency and improve confidence in their …
Cognitive Effects Of The Bet Protein Inhibitor Apabetalone: A Prespecified Montreal Cognitive Assessment Analysis Nested In The Betonmace Randomized Controlled Trial,
2021
University of Nevada, Las Vegas
Cognitive Effects Of The Bet Protein Inhibitor Apabetalone: A Prespecified Montreal Cognitive Assessment Analysis Nested In The Betonmace Randomized Controlled Trial, Jeffrey Cummings, Gregory G. Schwartz, Stephen J. Nicholls, Aziz Khan, Chris Halliday, Peter P. Toth, Michael Sweeney, Jan O. Johansson, Norman C.W. Wong, Ewelina Kulikowski, Kamyar Kalantar-Zadeh, Kenneth Lebioda, Henry N. Ginsberg, Bengt Winblad, Henrik Zetterberg, Kausik K. Ray
School of Medicine Faculty Research
Background: Epigenetic changes may contribute importantly to cognitive decline in late life including Alzheimer's disease (AD) and vascular dementia (VaD). Bromodomain and extra-terminal (BET) proteins are epigenetic 'readers' that may distort normal gene expression and contribute to chronic disorders. Objective: To assess the effects of apabetalone, a small molecule BET protein inhibitor, on cognitive performance of patients 70 years or older participating in a randomized trial of patients at high risk for major cardiovascular events (MACE). Methods: The Montreal Cognitive Assessment (MoCA) was performed on all patients 70 years or older at the time of randomization. 464 participants were randomized …
A Roadmap For Building Data Science Capacity For Health Discovery And Innovation In Africa,
2021
McMaster University, Canada
A Roadmap For Building Data Science Capacity For Health Discovery And Innovation In Africa, Joseph Beyene, Solomon W. Harrar, Mekibib Altaye, Tessema Astatkie, Tadesse Awoke, Ziv Shkedy, Tesfaye B. Mersha
Statistics Faculty Publications
Technological advances now make it possible to generate diverse, complex and varying sizes of data in a wide range of applications from business to engineering to medicine. In the health sciences, in particular, data are being produced at an unprecedented rate across the full spectrum of scientific inquiry spanning basic biology, clinical medicine, public health and health care systems. Leveraging these data can accelerate scientific advances, health discovery and innovations. However, data are just the raw material required to generate new knowledge, not knowledge on its own, as a pile of bricks would not be mistaken for a building. In …
Determining Diagnosis Date Of Diabetes Using Structured Electronic Health Record (Ehr) Data: The Search For Diabetes In Youth Study,
2021
University of South Carolina
Determining Diagnosis Date Of Diabetes Using Structured Electronic Health Record (Ehr) Data: The Search For Diabetes In Youth Study, Kristin M. Lenoir, Lynne E. Wagenknecht, Jasmin Divers, Ramon Casanova, Dana Dabelea, Sharon Saydah, Catherine Pihoker, Angela D. Liese Ph.D., Debra Standiford, Richard Hamman, Brian J. Wells, The Search For Diabetes In Youth Study Group
Faculty Publications
Background Disease surveillance of diabetes among youth has relied mainly upon manual chart review. However, increasingly available structured electronic health record (EHR) data have been shown to yield accurate determinations of diabetes status and type. Validated algorithms to determine date of diabetes diagnosis are lacking. The objective of this work is to validate two EHR-based algorithms to determine date of diagnosis of diabetes. Methods A rule-based ICD-10 algorithm identified youth with diabetes from structured EHR data over the period of 2009 through 2017 within three children’s hospitals that participate in the SEARCH for Diabetes in Youth Study: Cincinnati Children’s Hospital, …
On The Extension Of Exponentiated Pareto Distribution,
2021
Cairo University, Giza, Egypt
On The Extension Of Exponentiated Pareto Distribution, Amal S. Hassan, Saeed Elsayed Hemeda, Said G. Nassr
Journal of Modern Applied Statistical Methods
In this study, an extended exponentiated Pareto distribution is proposed. Some statistical properties are derived. We consider maximum likelihood, least squares, weighted least squares and Bayesian estimators. A simulation study is implemented for investigating the accuracy of different estimators. An application of the proposed distribution to a real data is presented.
Systematic Review Of Polyherbal Combinations Used In Metabolic Syndrome,
2021
Aga Khan University
Systematic Review Of Polyherbal Combinations Used In Metabolic Syndrome, Amber Hanif Palla, Faridah Amin, Bilqees Fatima, Arooj Shafiq, Najeeb Ur Rehman, Ikram Ul Haq, Anwar-Ul-Hassan Gilani
Department of Biological & Biomedical Sciences
Background: Metabolic syndrome (MetS) is a multifactorial disease, whose main stay of prevention and management is life-style modification which is difficult to attain. Combination of herbs have proven more efficacious in multi-targeted diseases, as compared to individual herbs owing to the "effect enhancing and side-effect neutralizing" properties of herbs, which forms the basis of polyherbal therapies This led us to review literature on the efficacy of herbal combinations in MetS.
Methods: Electronic search of literature was conducted by using Cinnahl, Pubmed central, Cochrane and Web of Science, whereas, Google scholar was used as secondary search tool. The key words used …
A Clash Of Cultures: The Struggle Of Native Americans To Participate In Traditional Ecological Knowledge And Western Science Under California’S Marine Life Protection Act,
2021
Humboldt State University
A Clash Of Cultures: The Struggle Of Native Americans To Participate In Traditional Ecological Knowledge And Western Science Under California’S Marine Life Protection Act, John W. Corbett, Ruthie A. Maloney
IdeaFest: Interdisciplinary Journal of Creative Works and Research from Cal Poly Humboldt
This article comprehensively details the culture clash that took place between Native Americans, the North Group Science Panel, and the Science Advisory Team (SAT) involved in the Marine Life Protection Act (MLPA). In 1999, the California Legislature passed the Marine Life Protection Act to create a statewide, science-driven network of marine reserves along the 1,100 miles of the California coast. The MLPA was meant to protect marine areas from overharvesting, and an initiative was formed to create a state marine reserve system advised by regional science panels. The science panel, a public body, decided that Native Americans science was not …
Ovarian Cancer Epidemiology, Healthcare Access And Disparities (Orchid): Methodology For A Population-Based Study Of Black, Hispanic And White Patients With Ovarian Cancer,
2021
Duke University
Ovarian Cancer Epidemiology, Healthcare Access And Disparities (Orchid): Methodology For A Population-Based Study Of Black, Hispanic And White Patients With Ovarian Cancer, Tomi Akinyemiju, April Deveaux, Lauren Wilson, Anjali Gupta, Ashwini Joshi, Malcolm Bevel, Chioma Omeogu, Onyinye Ohamadike, Bin Huang, Maria Pisu, Margaret Liang, Molly Mcfatrich, Erin Daniell, Laura Jane Fish, Kevin Ward, Maria Schymura, Andrew Berchuck, Arnold L. Potosky
Biostatistics Faculty Publications
INTRODUCTION: Less than 40% of patients with ovarian cancer (OC) in the USA receive stage-appropriate guideline-adherent surgery and chemotherapy. Black patients with cancer report greater depression, pain and fatigue than white patients. Lack of access to healthcare likely contributes to low treatment rates and racial differences in outcomes. The Ovarian Cancer Epidemiology, Healthcare Access and Disparities study aims to characterise healthcare access (HCA) across five specific dimensions-Availability, Affordability, Accessibility, Accommodation and Acceptability-among black, Hispanic and white patients with OC, evaluate the impact of HCA on quality of treatment, supportive care and survival, and explore biological mechanisms that may contribute to …
Faculty Versus Student Repeatability On Evaluating Translucency Of The Anterior Dentition,
2021
Creighton University
Faculty Versus Student Repeatability On Evaluating Translucency Of The Anterior Dentition, James L. Sheets, David B. Marx, Nina Ariani, Valentim A. R. Barão, Alvin G. Wee
Department of Statistics: Faculty Publications
The objective was to compare the repeatability between dental faculty, whose clinical practice was primarily restorative dentistry, and final year dental students in categorizing the inherent translucency of images selected at random using either a 3- or 7-point scale (translucent to opaque). Digital images of anterior dentition were randomly selected based on inherent translucency. Thirty images (five were repeated) were randomized and categorized by 20 dental students and 20 faculty on their inherent translucency. Statistical analysis was performed using an F test for analysis of variance at 95% confidence interval. A covariance parameter estimate (CPE) was accomplished to compare the …
The Mediating/Moderating Role Of Cultural Context Factors On Self-Care Practices Among Those Living With Diabetes In Rural Appalachia,
2021
University of Kentucky
The Mediating/Moderating Role Of Cultural Context Factors On Self-Care Practices Among Those Living With Diabetes In Rural Appalachia, Brittany L. Smalls, Adebola Adegboyega, Ellen Combs, Matthew Rutledge, Philip M. Westgate, Md. Tofial Azam, Felipe De La Barra, Lovoria B. Williams, Nancy E. Schoenberg
Family and Community Medicine Faculty Publications
Background
The aim of this study was to examine whether cultural factors, such as religiosity and social support, mediate/moderate the relationship between personal/psychosocial factors and T2DM self-care in a rural Appalachian community.
Methods
Regression models were utilized to assess for mediation and moderation. Multilevel linear mixed effects models and GEE-type logistic regression models were fit for continuous (social support, self-care) and binary (religiosity) outcomes, respectively.
Results
The results indicated that cultural context factors (religiosity and social support) can mediate/moderate the relationship between psychosocial factors and T2DM self-care. Specifically, after adjusting for demographic variables, the findings suggested that social support may …
Math 671: Statistical Method I,
2021
University of Mississippi
An Evaluation Of The Organic Carbon Content Found In Fucus Vesiculosus And Ascophyllum Nodosum From Skutulsfjörður And Eyjafjörður, Iceland,
2021
SIT Study Abroad
An Evaluation Of The Organic Carbon Content Found In Fucus Vesiculosus And Ascophyllum Nodosum From Skutulsfjörður And Eyjafjörður, Iceland, Sylvie Alexander
Independent Study Project (ISP) Collection
In response to global warming and changing climate, carbon sequestration through macroalgal cultivation has emerged as a possible climate change mitigation technique. Macroalgal cultivation’s relationship to carbon sequestration however is still not well understood. It is imperative to understand macroalgae’s connection to carbon sequestration to evaluate if macroalgal cultivation can help combat climate change. There is a gap in literature regarding the carbon content of Icelandic macroalgae and therefore the contribution of Icelandic macroalgae to national and global carbon sequestration estimates. This paper aims to address this knowledge gap by evaluating organic carbon content of Fucus vesiculosus and Ascophyllum nodosum …
