Study Of 2,5-Diaminoimidazolone, A Mutagenic Product Of Oxidation Of Guanine In Dna,
2017
East Tennessee State University
Study Of 2,5-Diaminoimidazolone, A Mutagenic Product Of Oxidation Of Guanine In Dna, Hannah Catherine J. Pollard
Electronic Theses and Dissertations
2,5-diaminoimidazolone (Iz) is an important product of a 4-electron oxidation of guanine. The present research focuses on the mechanisms of formation of Iz via pathways initiated by guanine oxidation by one-electron oxidants (OEOs) generated by X-ray radiolysis in aqueous solutions. The kinetics of formation and yields of Iz in reactions of native highly polymerized DNA with different OEOs have been compared using an HPLC-based quantitative analysis of low-molecular products generated from the reaction of DNA-bound Iz with primary amines. Mechanisms of Iz formation in DNA have been investigated including oxygen and superoxide dependence as well as the hypothesis that 8-oxo-G, …
The Autophagy-Related Beclin-1 Protein Requires The Coiled-Coil And Bara Domains To Form A Homodimer With Submicromolar Affinity,
2017
Broad Institute of MIT and Harvard
The Autophagy-Related Beclin-1 Protein Requires The Coiled-Coil And Bara Domains To Form A Homodimer With Submicromolar Affinity, Matthew J. Ranaghan, Michael A. Durney, Michael F. Mesleh, Patrick R. Mccarren, Colin W. Garvie, Douglas S. Daniels, Kimberly L. Carey, Adam P. Skepner, Beth Levine, Jose R. Perez
Chemistry Faculty Publications
Beclin-1 (BECN1) is an essential component of macroautophagy. This process is a highly conserved survival mechanism that recycles damaged cellular components or pathogens by encasing them in a bilayer vesicle that fuses with a lysosome to allow degradation of the vesicular contents. Mutations or altered expression profiles of BECN1 have been linked to various cancers and neurodegenerative diseases. Viruses, including HIV and herpes simplex virus 1 (HSV-1), are also known to specifically target BECN1 as a means of evading host defense mechanisms. Autophagy is regulated by the interaction between BECN1 and Bcl-2, a pro-survival protein in the apoptotic pathway that …
Coupled Plasmon/Molecule Dynamics Near Core-Shell Nanoparticles: Synthesis, Ultrafast Characterization, And Quantum/Classical Modeling,
2017
Louisiana State University and Agricultural and Mechanical College
Coupled Plasmon/Molecule Dynamics Near Core-Shell Nanoparticles: Synthesis, Ultrafast Characterization, And Quantum/Classical Modeling, Holden Tyler Smith
LSU Doctoral Dissertations
In this dissertation, the resonance coupling of chromaphoric dyes adsorbed on the surface of plasmonic nanoparticles (NPs) are investigated using a combined theoretical and experi- mental approach. Colloidal gold, gold-silver core-shell, silver-gold core-shell, and gold-silver- gold core-shell-shell NPs are considered. These NPs are thiolated with mercaptosuccinic acid, and malachite green dyes are adsorbed to the surface of the nanoparticle (NP) via elec- trostatic interactions. Second harmonic generation is used to determine the surface to the isotherm of the molecular dyes to the colloidal nanoparticle surface. Adsorption isotherms show that the SHG intensity increases as the concentration of dye increases, reaching …
Dendritic Plasmonics For Mid-Infrared Spectroscopy,
2017
University of Western Ontario
Dendritic Plasmonics For Mid-Infrared Spectroscopy, Francois Lagugne-Labarthet, Gregory Q. Wallace, Hayden C. Foy, Scott M. Rosendahl
Chemistry Publications
Metallic nanostructures that exhibit tailored optical resonances spanning from the near to mid-infrared spectral range are of particular interest for spectroscopic and optical measurements in these spectral domains that can benefit from localized surface-enhancement effects. Plasmon resonances shifted in the near or mid-infrared range could be used to further enhance the excitation and/or the emission of an optical process. Surface-enhanced infrared absorption (SEIRA) is one of such processes and can particularly benefit from plasmon-enhanced local fields yielding an increase in sensitivity towards the detection of an analyte. Herein, we have fabricated a series of gold dendritic nanostructures, prepared by electron-beam …
Special Issue On Supercapacitors,
2017
College of Materials Science & Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing, 210016, P. R. China;
Electrochemical Capacitors Based On Anion-Graphite Intercalation Compounds,
2017
State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry,Chinese Academy of Sciences, Changchun 130022, China;
Electrochemical Capacitors Based On Anion-Graphite Intercalation Compounds, Hong-Yu Wang, Hui Fan, Xiao-Hong Wang, Li Qi
Journal of Electrochemistry
Anions can be electrochemically intercalated into a graphite electrode with a reversible capacity as high as 120 mAh·g-1 at the high potential near 5 V vs. Li/Li+. Besides, graphite is environmentally benign, economic and abundant in China. Therefore, graphite is a very promising positive electrode material for asymmetric capacitors using non-aqueous electrolytes. However, the performance of graphite positive electrode is quite sensitive to various affecting factors, such as the compositions of electrolyte solutions, graphite type and ambient temperature, and so on. In the platform of activated carbon/graphite capacitors, the electrochemical behavior of anion-graphite intercalation compounds can be …
Strategies To Enhance Energy Density For Supercapacitors,
2017
Laboratory of Clean Energy Chemistry and Materials, State Key Laboratory of Solid Lubrication, Lanzhou Institute of Chemical Physics, Lanzhou 730000, P. R. China;
Strategies To Enhance Energy Density For Supercapacitors, Jun-Wei Lang, Xu Zhang, Ru-Tao Wang, Xing-Bin Yan
Journal of Electrochemistry
The biggest advantage of supercapacitor lies in not only the excellent pulse and fast charging-discharging performance, but also the characteristics of long cycle life and wide operating temperature window with no pollution. However, the energy density of supercapacitor is low. In this paper, the working principle, the development status, defects and improvement method of supercapacitors are introduced. Based on the research workes of the supercapacitors with high energy density in our group, combined with the literature reports in recent years, the strategies to promote the energy density of supercarpacitors will be focused. The strategies for the enhancement of energy density …
Attempts To Improve The Energy Capacity Of Capacitive Electrochemical Energy Storage Devices,
2017
Department of Chemical and Environmental Engineering, and Centre for Sustainable Energy Technologies, Faculty of Science and Engineering, University of Nottingham Ningbo China, Ningbo 315100, Zhejiang, China;
Attempts To Improve The Energy Capacity Of Capacitive Electrochemical Energy Storage Devices, Lin-Po Yu, George Z. Chen
Journal of Electrochemistry
This article reviews selected literatures from the authors’ research group on the development of capacitive electrochemical energy storage (EES) devices, focusing on supercapacitors and supercapatteries at both the electrode material level and device level. Electronically conducting polymers (ECPs) and transition metal oxides (TMOs) composited with carbon nanotubes (CNTs) were found to be able to improve the capacitance performance as capacitive faradaic storage electrode. Carbon materials, like activated carbon (Act-C) and carbon black, were used to fabricate non-faradaic capacitive storage electrode. It was found that the electrode capacitance balance can effectively extend the maximum charging voltage (MCV) of the supercapacitor, and …
Porous Carbon Materials Produced By Koh Activation For Supercapacitor Electrodes,
2017
CAS Key Laboratory of Materials for Energy Conversion & Department of Materials Science and Engineering, & iChEM, University of Science and Technology of China, Hefei 230026, P. R. China;
Porous Carbon Materials Produced By Koh Activation For Supercapacitor Electrodes, Jiang-Lin Ye, Yan-Wu Zhu
Journal of Electrochemistry
Porous carbon materials with high specific surface area and excellent conductivity have wide applications in supercapacitor electrodes. Much effort has been made to synthesize and tailor the microstructures of porous carbon materials via various activation procedures (physical and chemical activations). In particular, the chemical activation using potassium hydroxide (KOH) as an activating reagent is promising because of the well-defined micropore size distribution and ultrahigh specific surface area up to 3000 m2·g-1 of the resulting porous carbons. Based mainly on the previous works taken by the authors and collaborators in the field, we have summarized the activation mechanism …
Recent Advances On Carbon And Transition Metallic Compound Electrodes For High-Performance Supercapacitors,
2017
MOE of the Key Laboratory of Bioinorganic and Synthetic Chemistry, KLGHEI of Environment and Energy Chemistry, School of Chemistry, Sun Yat-Sen University, Guangzhou 510275, People’s Republic of China;
Recent Advances On Carbon And Transition Metallic Compound Electrodes For High-Performance Supercapacitors, Dun Lin, Xi-Yue Zhang, Yin-Xiang Zeng, Ming-Hao Yu, Xi-Hong Lu, Ye-Xiang Tong
Journal of Electrochemistry
Supercapacitors (SCs) have stimulated intensive interests for their promising applications in electric vehicles and portable electronics, etc. Electrode material is the most important key component of SCs, which vastly determines the performance of SCs. Carbon and transition metallic compound materials have attracted considerable attention and been widely explored as electrode materials. However, the insufficient capacitance of carbon materials and unsatisfactory conductivity and cyclic stability of transition metallic compounds severely limit their implementation as robust SC electrodes. Herein, we highlight our recent efforts to boost the capacitive performance of carbon and metal oxide/nitride electrodes by rationally structural and componential design. The …
Lithium Ion Hybrid Capacitor With High Energy Density,
2017
Institute of Electrical Engineering, Chinese Academy of Sciences, Beijing 100190, PR China;University of Chinese Academy of Sciences, Beijing 100049, PR China;
Lithium Ion Hybrid Capacitor With High Energy Density, Xian-Zhong Sun, Xiong Zhang, Kai Wang, Yan-Wei Ma
Journal of Electrochemistry
Lithium ion hybrid capacitors are electrochemical energy storage devices combining the advantages of both Li-ion battery and electrochemical capacitor. They can be extensively used in many fields. However, the commercialization of lithium ion hybrid capacitor has been encountered several problems, e.g., the device structure design, the screening of materials, the pre-lithiation process, and the interface between electrolyte and electrode, etc. This review summarizes the recent research advances in lithium ion hybrid capacitor with high energy density, including the selection of the active materials in cathode/anode and the separator, the pre-lithiation method using the three-electrode structure, the high- and low-temperature performances, …
Template Induced Fabrication Of Nitrogen Doped Carbon Sheets As Electrode Materials In Supercapacitors,
2017
School of Chemistry and chemical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China;
Template Induced Fabrication Of Nitrogen Doped Carbon Sheets As Electrode Materials In Supercapacitors, Tao Huang, Guang-Zhi Tao, Chong-Qing Yang, Deng Lu, Lie Ma, Dong-Qing Wu
Journal of Electrochemistry
Due to the good electrical conductivity, high specific surface area, and excellent chemical/mechanical stability, carbon nanomaterials with two-dimensional morphology have gradually become the hot topic of the research on supercapacitors. Herein, we report for the first time the fabrication of nitrogen doped carbon sheets (NCSs). In our approach, the sheet-like magnisum aluminum (MgAl) layered double hydroxide was used as the hard template, which was mixed with o-phenylene diamine and iron chloride. The following thermal treatment could render the polymerization and carbonization of o-phenylene diamine. The NCSs with ordered hexagonal architectures were formed by final etching process of the thermally treated …
Preparation And Characterization Of Cellulose Acetate-Based Separator For Lithium-Ion Batteries,
2017
Coal Engineering College, Shanxi Datong University, Datong 037003, Shanxi, China;
Preparation And Characterization Of Cellulose Acetate-Based Separator For Lithium-Ion Batteries, Hua-Feng Luo, Yuan-Dong Qiao
Journal of Electrochemistry
To improve the electrolyte wettability and thermal resistance of separators used for lithium-ion battery, a novel cellulose acetate (CA)-based separator is facilely prepared by non-solvent induced phase separation (NIPS) wet-process and investigated in lithium-ion batteries. Systematical investigations including morphological characterization, electrolyte wettability and thermal resistance testing were carried out. The results demonstrated that the CA-based separator exhibited well developed three-dimensional porous structures with porosity up to 65%, which is 1.5 times higher than that of PE separator. The CA separator also showed excellent electrolyte uptake (285%) and thermal stability at 150 oC for 30 min. Compared with the commercial …
An Aqueous Zn-Ion Capacitor,
2017
Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Shandong Qingdao 266101, China;
An Aqueous Zn-Ion Capacitor, Jing-Wen Zhao, Jia-Jia Li, Peng-Xian Han, Guang-Lei Cui
Journal of Electrochemistry
We first present a new aqueous zinc-ion (Zn-ion) capacitor based on vanadium pentoxide (V2O5) cathode, activated carbon (AC) anode, and 2 mol·L-1 zinc trifluoromethanesulfonate (Zn(TfO)2) electrolyte. The Zn-ion capacitor possesses a wide electrochemical window of 1.4 V, good rate capability and cycling stability. The XRD data demonstrates that the Zn2+ ion serving as the charge carrier could be reversibly intercalated into the V2O5. This capacitor delivered a power density of 181 W·kg-1 and an energy density of 4.5 Wh·kg-1 at 1000 mA·g-1. This work …
Nucleotide-Dependent Preferential Localization Of Ras In Model Membranes With Lipid Raft Nanodomains,
2017
Marquette University
Nucleotide-Dependent Preferential Localization Of Ras In Model Membranes With Lipid Raft Nanodomains, Anna Shishina
Dissertations (1934 -)
Membrane proteins constitute a third of all proteins in the cell and more than 50% of drug targets. However, the analysis of membrane proteins has many challenges owing to their partially hydrophobic surfaces, flexibility and lack of stability. One example of an essential membrane protein is Ras superfamily. Ras is a small monomeric GTPase involved in regulation of cell growth, proliferation and differentiation. Therefore, Ras and its effectors are among the most important targets for cancer therapy. A detailed knowledge of the processes occurring during signal propagation via Ras might help to elucidate the mechanisms of the involved signal cascades. …
Spin-Imbalance In A 2d Fermi-Hubbard System,
2017
Princeton University
Spin-Imbalance In A 2d Fermi-Hubbard System, Peter Brown, Debayan Mitra, Elmer Guardado-Sanchez, Peter Schauß, Stanimir Kondov, Ehsan Khatami, Thereza Paiva, Nandini Trivedi, David Huse, Waseem Bakr
Faculty Publications
The interplay of strong interactions and magnetic fields gives rise to unusual forms of superconductivity and magnetism in quantum many-body systems. Here, we present an experimental study of the two-dimensional Fermi-Hubbard model—a paradigm for strongly correlated fermions on a lattice—in the presence of a Zeeman field and varying doping. Using site-resolved measurements, we revealed anisotropic antiferromagnetic correlations, a precursor to long-range canted order. We observed nonmonotonic behavior of the local polarization with doping for strong interactions, which we attribute to the evolution from an antiferromagnetic insulator to a metallic phase. Our results pave the way to experimentally mapping the low-temperature …
Phase Behavior Of Binary And Polydisperse Suspensions Of Compressible Microgels Controlled By Selective Particle Deswelling,
2017
Paul Scherrer Institut
Phase Behavior Of Binary And Polydisperse Suspensions Of Compressible Microgels Controlled By Selective Particle Deswelling, A. Scotti, U. Gasser, E. S. Herman, Jun Han, A. Menzel, L. Andrew Lyon, A. Fernandez-Nieves
Biology, Chemistry, and Environmental Sciences Faculty Articles and Research
We investigate the phase behavior of suspensions of poly(N-isopropylacrylamide) (pNIPAM) microgels with either bimodal or polydisperse size distribution. We observe a shift of the fluid-crystal transition to higher concentrations depending on the polydispersity or the fraction of large particles in suspension. Crystallization is observed up to polydispersities as high as 18.5%, and up to a number fraction of large particles of 29% in bidisperse suspensions. The crystal structure is random hexagonal close-packed as in monodisperse pNIPAM microgel suspensions.We explain our experimental results by considering the effect of bound counterions. Above a critical particle concentration, these cause deswelling of the largest …
Distinct Ice Patterns On Solid Surfaces With
Various Wettabilities,
2017
Chinese Academy of Sciences
Distinct Ice Patterns On Solid Surfaces With Various Wettabilities, Jie Liu, Chongqin Zhu, Kai Liu, Ying Jiang, Yanlin Song, Joseph S. Francisco, Xiao Cheng Zeng, Jianjun Wang
Xiao Cheng Zeng Publications
No relationship has been established between surface wettability and ice growth patterns, although ice often forms on top of solid surfaces. Here, we report experimental observations obtained using a process specially designed to avoid the influence of nucleation and describe the wettability-dependent ice morphology on solid surfaces under atmospheric conditions and the discovery of two growth modes of ice crystals: along-surface and off-surface growth modes. Using atomistic molecular dynamics simulation analysis, we show that these distinct ice growth phenomena are attributable to the presence (or absence) of bilayer ice on solid surfaces with different wettability; that is, the formation of …
Avoiding The Cubic Equation In Finding The Van Der Waals Fluid's Vapor Pressures,
2017
University of Connecticut
Avoiding The Cubic Equation In Finding The Van Der Waals Fluid's Vapor Pressures, Carl W. David
Chemistry Education Materials
The van der Waals coexistence curve of liquid and vapor volumes as functions of the temperature (all in reduced coordinates) as well as the correspponding vapor pressures at these temperatures, is obtained using SageMath, a symbolic calculus/algebra computer programming language.The lack of correspondence of the coexistence locus’ analytical form as obtained herein and those of Lekner remains disconcerting.
Optical Studies Of The Solution Phase Reduction And Stabilization Of Indigo Tetrasulfonate In Polyelectrolyte Complexes,
2017
Central Washington University
Optical Studies Of The Solution Phase Reduction And Stabilization Of Indigo Tetrasulfonate In Polyelectrolyte Complexes, Becca Hoene, Dion Rivera
All Faculty Scholarship for the College of the Sciences
Ultraviolet-visible (UV-vis) and fluorescence spectroscopy have been used to characterize the polyelectrolyte complexes (PECs) formed when potassium indigo tetrasulfonate (ITS) interacts with poly diallydimethylammonium chloride (PDADMAC) through columbic attraction in the presence of the reducing agent sodium bisulfite, NaHSO3. The PDADMAC facilitates both the reduction of the ITS and the stabilization of the reduced state of the ITS in an atmospheric oxygen environment. Dilutions of the dye solution show that the PEC is stable to dilutions of at least 1 to 1000. UV–vis studies indicate that the reduced ITS (ITSred) forms what is likely a J-aggregate in the presence of …
