Synthesis Of Novel Glycosylidene-Based Quinolines,
2010
Seton Hall University
Synthesis Of Novel Glycosylidene-Based Quinolines, Peter H. Dobbelaar
Seton Hall University Dissertations and Theses (ETDs)
.
Development Of Novel Ahr Antagonists,
2010
University of Kentucky
Development Of Novel Ahr Antagonists, Hyosung Lee
University of Kentucky Doctoral Dissertations
Aryl hydrocarbon receptor (AHR) is a sensor protein, activated by aromatic chemical species for transcriptionally regulating xenobiotic metabolizing enzymes. AHR is also known to be involved in a variety of pathogenesis such as cancer, diabetes mellitus, cirrhosis, asthma, etc. The AHR signaling induced by xenobiotics has been intensively studied whereas its physiological role in the absence of xenobiotics is poorly understood. Despite a number of ligands of AHR have been reported thus far, further applications are still hampered by the lack of specificity and/or the partially agonistic activity. Thus, a pure AHR antagonist is needed for deciphering the AHR cryptic …
1, 2-Bis (Phenylsulfonyl)-1h-Indole As An Acceptor Of Organocuprate Nucleophiles,
2010
Dartmouth College
1, 2-Bis (Phenylsulfonyl)-1h-Indole As An Acceptor Of Organocuprate Nucleophiles, David C. Qian, Philip E. Alford, Tara L. S. Kishbaugh, Sean T. Jones, Gordon W. Gribble
Dartmouth Scholarship
1,2-Bis(phenylsulfonyl)-1H-indole is a novel example of an electron-deficient indole that undergoes nucleophilic attack at C-3. Though a variety of other organometallic nucleophiles fail to engender nucleophilic substitution, organocuprates produce 3-substituted 2-(phenylsulfonyl)-1H-indoles. These reactions contribute to the growing number of examples of nucleophilic addition to the indole core.
Microporous Organic Polymers: Synthesis And Post Synthetic Modifications,
2010
Wilfrid Laurier University
Microporous Organic Polymers: Synthesis And Post Synthetic Modifications, Phillip Andrew Kerneghan
Theses and Dissertations (Comprehensive)
Microporous solids are an important class of materials that have been studied extensively. Newer to this field are Microporous Organic Polymers (MOPs) which are networks constructed from smaller organic building blocks and exhibit large surface areas, small pore sizes and low densities. It is due to these characteristics that MOPs have attracted attention because of their potential use in applications such as catalysis, chemical separations and gas storage.
In this thesis is described the synthesis of two novel MOPs, the first of which being a network based on benzenediboronic acid and triptycene building blocks linked together by boronate esters. This …
Synthesis Of Urethane Acrylate Macromer From Palm Oil-Based Polyol And Its Application As A Resin For Dental Composite.,
2010
Universiti Malaya
Synthesis Of Urethane Acrylate Macromer From Palm Oil-Based Polyol And Its Application As A Resin For Dental Composite., Fadheel A. A. Alsanabani
Student Works (2010-2019)
A slightly branched urethane acrylate macromer (UAM) was synthesized by reacting palm oil-based polyol with excess amounts of polymeric methylene diphenyl diisocyanate (MDI) to form urethane prepolymer, then reacted with 2-hydroxyethyl methacrylate (HEMA) and FT-IR spectroscopy confirmed the urethane and grafted acrylate groups. 0.2% by weight of camphoroquinone (CQ) and 0.8% by weight of ethyl-4-N,N-dimethylamino-benzoate (4EDMAB) by weight were added to render the experimental resins light-curable. Their viscosity, percentage of degree of conversion (%DC) and cross-linking density (CLD), percentage of volumetric polymerization shrinkage (%VPS), water sorption and solubility, flexural strength, modulus of elasticity and toughness were determined and compared to …
