Fabrication Of Polymer Monoliths Within The Confines Of Non-Transparent 3d-Printed Polymer Housings,
2020
University of Amsterdam
Fabrication Of Polymer Monoliths Within The Confines Of Non-Transparent 3d-Printed Polymer Housings, Noor Abdulhussain, Suhas H. Nawada, Sinéad Currivan, Marta Passamonti, Peter J. Schoenmakers
Articles
In the last decade, 3D-printing has emerged as a promising enabling technology in the field of analytical chemistry. Fused-deposition modelling (FDM) is a popular, low-cost and widely accessible technique. In this study, RPLC separations are achieved by in-situ fabrication of porous polymer monoliths, directly within the 3D-printed channels. Thermal polymerization was employed for the fabrication of monolithic columns in optically non-transparent column housings, 3D-printed using two different polypropylene materials. Both acrylate-based and polystyrene-based monoliths were created. Two approaches were used for monolith fabrication, viz. (i) in standard polypropylene (PP) a two-step process was developed, with a radical initiated wall-modification step …
The Synthesis Of A Mepeg-Based Hydroxide Conducting Electrolyte And The Optimization Of The Mepeg-Tosylation Reaction,
2020
University of Mississippi
The Synthesis Of A Mepeg-Based Hydroxide Conducting Electrolyte And The Optimization Of The Mepeg-Tosylation Reaction, Andrew Ladner
Honors Theses
As society is becoming increasingly aware of the effects of climate change and the ever-looming threat of a fuel shortage, exploring green and renewable alternative energy production, such as fuel cells, is paramount. This project investigates the synthesis of a polyethylene glycol monomethyl ether (MePEGn) based polymer as well as the optimization of the MePEG Tosylation reaction. The MePEG explored contains seven polymerized ethoxy groups (MePEG7). The MePEG7 polymer was modified by substituting a positively-charged trimethylamine group in the place of the alcohol functional group at the end of the PEG chain. The reason for …
Intrinsic Buffer Hydroxyl Radical Dosimetry For Hydroxyl Radical Protein Footprinting,
2020
University of Mississippi
Intrinsic Buffer Hydroxyl Radical Dosimetry For Hydroxyl Radical Protein Footprinting, Addison Roush
Honors Theses
Hydroxyl radical protein footprinting (HRPF) coupled to mass spectrometry is a powerful technique for the analysis of protein topography as it generates covalent mass labels that can survive downstream sample handling, and it is sensitive to the solvent accessibility of amino acid sidechains. Of the multiple platforms for HRPF, fast photochemical oxidation of proteins (FPOP) utilizes a pulsed 248 nm KrF excimer laser to label proteins by photolyzing hydrogen peroxide. FPOP is the most widely used HRPF platform because it labels proteins faster than unfolding can occur. Variations in FPOP sample conditions make it difficult to compare results between experiments …
Investigation Of The History Of Fingerprinting, Advancements In The Field, And Development Of Potential Methods That Could Improve The Detection Of Endogenous And Exogenous Drugs In Latent Prints,
2020
University of Mississippi
Investigation Of The History Of Fingerprinting, Advancements In The Field, And Development Of Potential Methods That Could Improve The Detection Of Endogenous And Exogenous Drugs In Latent Prints, Kristen Malloy
Honors Theses
When someone thinks of fingerprinting, they are most likely going to picture how a latent print is matched to the fingerprint of a suspect based on ridge pattern analysis. However, there is much more information that can be obtained from a latent print. The work performed in this thesis focuses the detection of exogenous and endogenous drugs in latent prints. The experiments performed analyzed fingerprints from volunteers that were contaminated with one of three common painkillers: acetaminophen, acetylsalicylic acid (ASA), and ibuprofen. Three different instruments were tested for this purpose: MALDI-MS, ATR-FTIR, and LC-MS. Based on the results gathered, it …
Comparison Of The Vibrational Modes Of Thiolated Gold Nanoparticles Undergoing Core-Conversions Via Raman Spectroscopy,
2020
University of Mississippi
Comparison Of The Vibrational Modes Of Thiolated Gold Nanoparticles Undergoing Core-Conversions Via Raman Spectroscopy, William Gregory Cannella Jr.
Honors Theses
In this project, the vibrational characteristics/vibrational modes are explored via Raman Spectroscopy for thiolated-gold nanoparticles. This class of compounds is also known as gold nanoparticles (AuNPs). They remain of great interest in research areas such as catalysis, gold dependent nanoelectronics, drug delivery, and sensing, due to their unique size-dependent optical, chiroptical, and electronic properties. Vibrational spectroscopy of thiolated gold nanoparticles are oftentimes considered nontrivial as the compounds strongly absorb light in the visible region of the electromagnetic spectrum, are generally considered weak scatterers, and give off large amounts of fluorescence. This combined with their black appearance, susceptibility to localized heating, …
Glucose Oxidase And Prussian Blue Nanoparticles Encapsulated Within A Xerogel For Electrochemical Detection Of Glucose,
2020
Coastal Carolina University
Glucose Oxidase And Prussian Blue Nanoparticles Encapsulated Within A Xerogel For Electrochemical Detection Of Glucose, Daniel Baker
Honors Theses
Recent literature reports examples of electrochemical biosensor systems based on the encapsulation of enzymes and metal nanoparticles into a xerogel for the detection of biologically important compounds, such as glucose. While these systems are very successful with acceptable detection limits and linear ranges. However, Prussian Blue modified electrodes have been shown to be better than metal electrodes for the detection of hydrogen peroxide. Here, a biosensor system where a xerogel in formed with both glucose oxidase and Prussian Blue nanoparticles.
Using Tandem Mass Spectrometry And Irmpd Spectroscopy To Determine The Intrinsic Reactions Of Uranyl-Containing Ions,
2020
Duquesne University
Using Tandem Mass Spectrometry And Irmpd Spectroscopy To Determine The Intrinsic Reactions Of Uranyl-Containing Ions, Irena Tatosian
Electronic Theses and Dissertations
Developing a comprehensive understanding of the intrinsic reactivity of uranium-containing species remains an important goal, as it may influence future developments in areas ranging from new approaches to nuclear fuel processing to studies of the migration and fate of the element in the environment. At a more fundamental level, such studies contribute to the understanding of the role that 5-f electrons may play in chemical bonding, the so called “f-electron challenge”. Electrospray ionization (ESI) is an effective way to generate gas-phase complexes containing uranium and uranyl ions for subsequent studies of intrinsic structure and reactivity. Studies in the gas-phase are …
N-Terminal Imine Derivatization For Enhanced De Novo Peptide Sequencing: A Study Of The Fragmentation Pattern Generated From Cid Of Peptide-Imines,
2020
Duquesne University
N-Terminal Imine Derivatization For Enhanced De Novo Peptide Sequencing: A Study Of The Fragmentation Pattern Generated From Cid Of Peptide-Imines, Khiry L. Patterson
Electronic Theses and Dissertations
In this work, the fragmentation pattern derived from model peptides derivatized to create N-terminal imines (Schiff bases) were evaluated. Collision-induced dissociation of the protonated peptide-imines ([M+H]+) generally produced complete series of the sequence informative an and bn ions, now undoubtedly characteristic of the peptide ion species. A novel product ion was also observed, denoted the yǂ ion, determined by IRMPD spectroscopy and density functional theory to be generated from the elimination of the N-terminal amino acid residue despite the N-terminal modification. It was concluded the pathway involved a nucleophilic attack by an amide nitrogen and …
Heteroatom-Doped Chemical Vapor Deposition Carbon Ultramicroelectrodes,
2020
East Tennessee State University
Heteroatom-Doped Chemical Vapor Deposition Carbon Ultramicroelectrodes, Alexis Sanwick
Undergraduate Honors Theses
Metal nanoparticles have been a primary focus in areas of catalysis and electrocatalysis applications as a result of their large surface area-to-volume ratios. While there is an increased interest in understanding the properties and behaviors of metal nanoparticles, they can become expensive over time. Recent research has incorporated the idea of using heteroatom-doped materials as a cheaper catalytic alternative to metal nanoparticles. In this study nitrogen-doping and phosphorous-doping techniques were applied to chemical vapor-deposited carbon ultramicroelectrodes in order to study the electrocatalytic properties toward the oxygen reduction reaction and the enhanced affinity for the deposition of gold nanoparticles onto the …
Gold Nanoparticles: Core Conversion Of Au144(Sch2ch2ph)60 To Au99(Sph-Ch3)42 Using Aromatic Thiolate Ligands And Crystallization Of Au99(Sph-Ch3)42,
2020
University of Mississippi
Gold Nanoparticles: Core Conversion Of Au144(Sch2ch2ph)60 To Au99(Sph-Ch3)42 Using Aromatic Thiolate Ligands And Crystallization Of Au99(Sph-Ch3)42, Elizabeth Turnage
Honors Theses
The purpose of this thesis is to synthesize Au144(SCH2CH2Ph)60 using a two-step synthesis reaction, and then using this product to conduct a core conversion from Au144(SCH2CH2Ph)60 to Au99(SPh-CH3)42. The Au99(SPh-CH3)42 product will then be used to attempt to form crystals using five different crystal set-up methods. Au144(SCH2CH2Ph)60 is made with aliphatic thiolate ligands, and when it is placed in a mixture containing excess para-methyl benzenethiol, it undergoes a …
Electrochemical Reduction Of Carbon Dioxide And Carbon Monoxide For The Production Of Green Fuels And Chemicals.,
2020
University of Louisville
Electrochemical Reduction Of Carbon Dioxide And Carbon Monoxide For The Production Of Green Fuels And Chemicals., Jacob M. Strain
Electronic Theses and Dissertations
It has become apparent that closing the carbon cycle on this planet in order to mitigate disastrous consequences of runaway global warming has become one of the most pressing issues of our civilization. One of the ways we need to accomplish this goal is by finding news methods to generate fuels that will be carbon neutral. Renewable fuels and green chemicals will be a major component of closing the carbon cycle and restoring our planet’s ecosystem into a sense of balance. A method that can help achieve this goal is the reduction of CO2. If CO2 can …
Identification And Quantification Of Classic, Prescription, And Synthetic Opioids In Hair By Liquid Chromatography Tandem Mass Spectrometry (Lc/Ms/Ms),
2020
CUNY John Jay College
Identification And Quantification Of Classic, Prescription, And Synthetic Opioids In Hair By Liquid Chromatography Tandem Mass Spectrometry (Lc/Ms/Ms), Natalia A. Platosz
Student Theses
The current use and misuse of synthetic and prescription opioids in the US has reached epidemic status. According to the US Department of Health and Human Services, every day more than 130 people in the US die after overdosing on opioids, and 2.1 million had an opioid use disorder in 2016. Hair is becoming an alternative matrix of increasing interest in forensic toxicology to investigate drug use and abuse patterns due to its long window of detection. The focus of this project was to develop and validate a method that simultaneously detects and quantifies 27 classic, prescription and synthetic opioids …
Comparison Of Three Analytical Techniques For General Characterisation Of Selected Algae And Cyanobacteria,
2020
Universiti Malaya
Comparison Of Three Analytical Techniques For General Characterisation Of Selected Algae And Cyanobacteria, Mohamed Iqbal Suhaina Nashath
Student Works (2020-2029)
Algae and cyanobacteria maintain the oxygenation of earth, and are utilised as biofuels, biofertilizers and nutrition feed. The characterisation of algae and cyanobacteria through conventional methods require technical expertise, laborious sample preparation, and moderately expensive instruments and reagents. Hence, in this study, selected bioanalytical techniques with minimal sample preparation were incorporated, to simplify the characterisation of algae and cyanobacteria. The objectives of this research were to study the phylogenetic relationship of the selected algae and cyanobacteria via the 23S plastid ribosomal ribonucleic acid (rRNA) and 18S rRNA biomarkers; to validate the presence of the microcystin synthetase (mcy) gene cluster encoding …
Functional Nanomaterials By Combining Aminooxy Chemistry And Iodine Activation At Momolayer Protected Clusters.,
2020
University of Louisville
Functional Nanomaterials By Combining Aminooxy Chemistry And Iodine Activation At Momolayer Protected Clusters., Tirtha Raj Sibakoti
Electronic Theses and Dissertations
Aminooxy (-ONH2) groups are most commonly known for their chemoselective reaction with carbonyl compounds (aldehydes/ketones) under mild reaction conditions. Aminooxy-based click chemistry is a versatile means of ligation as evidenced by broad application in material science, biology, biochemistry, analytical chemistry, and nanoscience. Our work exploits the facile reaction of aminooxy groups presented on the surface of gold (Au) or palladium (Pd) monolayer protected clusters (MPCs) with various aldehydes via oximation reactions, which form the robust oxime ether adducts. The functionalization of hexanethiolate-stabilized Au MPCs with a newly developed trifunctional amine-containing aminooxy alkanethiol ligand by thiol place-exchange affords aminooxylated …
Surface Chemistry And Surface Properties Of Energetic Nitrocellulose (Nc),
2020
Seton Hall University
Surface Chemistry And Surface Properties Of Energetic Nitrocellulose (Nc), Henry Grau
Seton Hall University Dissertations and Theses (ETDs)
This research describes an investigation into the wettability of nitrocellulose (NC), most importantly to nitroglycerin (NG), which are key components of formulations used to propel military ammunition. NG demonstrates complete wetting of NC and, overtime, NG sweats on the NC surface and leaks out. The leaking out of NG from the solid formulation is a known cause of fires and explosions resulting from storage. The origin of this research is inspired by the need to engineer a solution to leakage problems of energetic plasticizer in NC based propellant. While searching for a viable material for a specific application, we journeyed …
Analysis Of Petroleum Products For Forensic And Environmental Applications,
2020
Longwood University
Analysis Of Petroleum Products For Forensic And Environmental Applications, Sarah Ghali, Sarah Porter
Virtual 2020 Spring Student Showcase for Research and Creative Inquiry
In both forensic and environmental applications, it is often important to identify ignitable liquid (IL) residues, to find a suspect or to clean up an oil spill. The ASTM method is commonly used; the extraction methods vary, but the data collection is the same. The instrument used in the ASTM method is gas chromatography mass spectroscopy (GC-MS), which allows a visual identification of the IL contaminating the sample. In this study, the use of Fourier transform infrared spectrometry (FTIR) was used in conjunction with chemometric analysis. Samples were prepared were to simulate an oil spill in natural waters. Two chemometric …
Analysis Of Phenolic Compounds In Moroccan Olive Oils By Hplc,
2020
Longwood University
Analysis Of Phenolic Compounds In Moroccan Olive Oils By Hplc, Hannah Meyls, Sarah Porter
Virtual 2020 Spring Student Showcase for Research and Creative Inquiry
Five extra virgin olive oils collected from farms in Morocco were analyzed for phenolic compounds. To complement these data, the chemical composition of the olive oils were analyzed by high-performance liquid chromatography. Several phenolic compounds were identified and quantified in the olive oils. Specifically, levels of oleuropein and luteolin were quantified in the low mg/kg range, and qualitative comparisons were made between the oil samples for tyrosol, vanillic acid, and apigenin. To compare extraction efficiency of different extraction solvents, methanol and DMF were used.
Surveillance Of Microplastic Pollution In Central Virginia Freshwater Ecosystems,
2020
Liberty University
Surveillance Of Microplastic Pollution In Central Virginia Freshwater Ecosystems, Alexandra Reddy
Senior Honors Theses
Aquatic organisms often mistake microplastic particulates (MP) as food and inadvertently ingest the particulates, which can biomagnify through the food chain. While MP ingestion is well-researched in the marine environment, little is known about microplastics in freshwater ecosystems. This project explores MP occurrence in an ecologically significant freshwater invertebrate: crayfish. Crayfish from two Central Virginia streams are collected to identify MP in the digestive tracts and gill filaments, and characterize the MP using analytical chemistry techniques. It was determined that MP were present in the digestive tracts and gill filaments of crayfish collected from both streams, and that MP frequency …
Extensible Interface For A Compact Spectrophotometer For Teaching Molecular Absorption In The Undergraduate Laboratory,
2020
Southern Illinois University Edwardsville
Extensible Interface For A Compact Spectrophotometer For Teaching Molecular Absorption In The Undergraduate Laboratory, Edward Navarre
SIUE Faculty Research, Scholarship, and Creative Activity
A simple computer interface for controlling a compact spectrograph for use as a spectrophotometer in an undergraduate teaching laboratory was developed. The project was implemented on a Raspberry Pi computer which permits the integration of a light source into the software. The interface was written in Python to facilitate modification by the user and because of its compatibility with several computing platforms. An implementation of the project in Linux on a Raspberry Pi computer is described.
Phosphorus Nmr And Its Application To Metabolomics,
2020
University of Nebraska-Lincoln
Phosphorus Nmr And Its Application To Metabolomics, Paula Evans, Fatema Bhinderwala, Robert Powers, Martha Morton, Thomas Smith
UCARE: Research Products
Stable isotopes are routinely employed by NMR metabolomics to highlight specific metabolic processes and to monitor pathway flux. 13C-carbon and 15N-nitrogen labeled nutrients are convenient sources of isotope tracers and are commonly added as supplements to a variety of biological systems ranging from cell cultures to animal models. Unlike 13C and 15N, 31P-phosphourous is a naturally abundant and NMR active isotope that doesn’t require an external supplemental source. To date, 31P NMR has seen limited usage in metabolomics because of a lack of reference spectra, difficulties in sample preparation, and an absence of two-dimensional (2D) NMR experiments. But, 31P NMR …
