Determining The Presence Of Biological Fluids In Peruvian Mummy Cloths Using The Liquid Chromatography Quadruple Time Of Flight Instrument,
2021
University of Northern Iowa
Determining The Presence Of Biological Fluids In Peruvian Mummy Cloths Using The Liquid Chromatography Quadruple Time Of Flight Instrument, Tim Perksen, Joshua Sebree Ph.D.
Fall 2021 - Chemical Analysis Class Projects
A poster presenting the processes used and the results of analyzing the cloth from Peruvian mummies for the presence of biological fluids.
Identification Of Natural Dyes In Ancient Peruvian Mummy Cloths Using Lc/Ms/Ms,
2021
University of Northern Iowa
Identification Of Natural Dyes In Ancient Peruvian Mummy Cloths Using Lc/Ms/Ms, Shailah Mathews, Joshua Sebree Ph.D.
Fall 2021 - Chemical Analysis Class Projects
A poster presenting the processes used and the results of analyzing the natural dyes used on cloth from Peruvian mummies.
Detecting Oceanic Salt In Peruvian Mummy Cloths Using Scanning Electron Microscopy,
2021
University of Northern Iowa
Detecting Oceanic Salt In Peruvian Mummy Cloths Using Scanning Electron Microscopy, Alexis Wirtz, Joshua Sebree Ph.D.
Fall 2021 - Chemical Analysis Class Projects
A poster presenting the processes and the results of analyzing cloth from Peruvian mummies for the presence of ocean salts.
Rapid Method For Consistency And Concentration Reporting Of Cannabidiol Using 1H-Nmr And Computer-Assisted Chemical Software,
2021
Portland State University
Rapid Method For Consistency And Concentration Reporting Of Cannabidiol Using 1H-Nmr And Computer-Assisted Chemical Software, Michael A. Fernando
University Honors Theses
An integrated computational method was demonstrated with hemp-derived Cannabidiol for an assessment of its purity and concentration. The sample was structurally verified, high purity, and 2.98 mmol/L in dissolved DMSO. The method presented is a general approach to assessing purity and concentration for any small organic molecule in CMC-Assist.
Facile Nitrogen-Doping Of Screen-Printed Carbon Electrodes For Detection Of Hydrogen Peroxide,
2021
East Tennessee State University
Facile Nitrogen-Doping Of Screen-Printed Carbon Electrodes For Detection Of Hydrogen Peroxide, Emmanuel Nkyaagye
Electronic Theses and Dissertations
Screen-printed carbon electrodes (SPCEs) have garnered much attention as sensors due to their simplicity and relatively low cost. However, to impart necessary selectivity and sensitivity for specific applications, modification of the SPCE surface, which can involve time-consuming procedures or costly equipment/materials, is typically required. Here, a simple nitrogen-doping process based on NH4OH was used to modify SPCEs prepared from commercially available ink for electrochemical detection of H2O2, a common target for biosensing strategies and indicator of cell stress. XPS studies showed that NH4OH treatment of SPCEs led to a nearly 5-fold increase …
Effects Of Localized Oxygen Production By Electrolysis On The First-Generation Glucose Sensor Response,
2021
University of Arkansas, Fayetteville
Effects Of Localized Oxygen Production By Electrolysis On The First-Generation Glucose Sensor Response, Nandita Halder
Graduate Theses and Dissertations
Glucose sensors are very important for detecting blood glucose both in vitro and in vivo. First-generation glucose biosensors were based on the glucose oxidase (GOx) enzyme using molecular oxygen as the electron acceptor and therefore oxygen dependent. Unfortunately for in-vivo work, oxygen in the body is variable and limited. Alternative approaches to overcome the oxygen dependency came with their own limitations. The widely used and commercially available ex-vivo glucose test strip uses a mediator in place of oxygen to free it from oxygen dependency. The mediator-based technology, in most cases cannot be transferred to in vivo applications due to the …
Amilorides Inhibit Sars-Cov-2 Replication In Vitro By
Targeting Rna Structures,
2021
Duke University
Amilorides Inhibit Sars-Cov-2 Replication In Vitro By Targeting Rna Structures, Martina Zafferani, Christina Haddad, Le Luo, Jesse Davila-Calderon, Liang-Yuan Chiu, Christian Shema Mugisha, Adeline G. Monaghan, Andrew A. Kennedy, Joseph D. Yesselman, Robert J. Gifford, Andrew W. Tai, Sebla B. Kutluay, Mei-Ling Li, Gary Brewer, Blanton S. Tolbert, Amanda E. Hargrove
Department of Chemistry: Faculty Publications
The SARS-CoV-2 pandemic, and the likelihood of future coronavirus pandemics, emphasized the urgent need for development of novel antivirals. Small-molecule chemical probes offer both to reveal aspects of virus replication and to serve as leads for antiviral therapeutic development. Here, we report on the identification of amiloride-based small molecules that potently inhibit OC43 and SARS-CoV-2 replication through targeting of conserved structured elements within the viral 5′-end. Nuclear magnetic resonance–based structural studies revealed specific amiloride interactions with stem loops containing bulge like structures and were predicted to be strongly bound by the lead amilorides in retrospective docking studies. Amilorides represent the …
Nuscon: A Community-Driven Platform For Quantitative Evaluation Of Nonuniform Sampling In Nmr,
2021
UConn Health
Nuscon: A Community-Driven Platform For Quantitative Evaluation Of Nonuniform Sampling In Nmr, Yulia Pustovalova, Frank Delaglio, D. Levi Craft, Haribabu Arthanari, Ad Bax, Martin Billeter, Mark J. Bostock, Hesam Dashti, D. Flemming Hansen, Sven G. Hyberts, Bruce A. Johnson, Krzysztof Kazimierczuk, Hengfa Lu, Mark Maciejewski, Tomas M. Miljenović, Mehdi Mobli, Daniel Nietlispach, Vladislav Orekhov, Robert Powers, Xiaobo Qu, Scott Anthony Robson, David Rovnyak, Gerhard Wagner, Jinfa Ying, Matthew Zambrello, Jeffrey C. Hoch, David L. Donoho, Adam D. Schuyler
Department of Chemistry: Faculty Publications
Although the concepts of nonuniform sampling (NUS) and non-Fourier spectral reconstruction in multidimensional NMR began to emerge 4 decades ago (Bodenhausen and Ernst, 1981; Barna and Laue, 1987), it is only relatively recently that NUS has become more commonplace. Advantages of NUS include the ability to tailor experiments to reduce data collection time and to improve spectral quality, whether through detection of closely spaced peaks (i.e., “resolution”) or peaks of weak intensity (i.e., “sensitivity”). Wider adoption of these methods is the result of improvements in computational performance, a growing abundance and flexibility of software, support from NMR spectrometer vendors, and …
Corrosion Prevention On Aluminum Alloy,
2021
Kennesaw State University
Corrosion Prevention On Aluminum Alloy, Andrea Brenner
Symposium of Student Scholars
Aluminum alloy (Al-alloy) is a widely used metal in construction, aerospace, aviation, and other necessary fields due to its lightweight and tweakable properties. However, corrosion is inevitable on metals and alloys, and that causes millions of dollars of revenue loss every year. Therefore, we propose to research fabricating coating to prevent corrosion on Al-alloy. This study uses an iron-based metal-organic framework (MOF) and polyurethane (PU) based composite coating to prevent corrosion on the Al-alloy. The makeup of the composite material is changed by varying the percentage of MOF. In addition, a binder is also used to enhance the homogenization between …
Impact Of The Water Content In The Therapeutic Deep Eutectic Solvents,
2021
Kennesaw State University
Impact Of The Water Content In The Therapeutic Deep Eutectic Solvents, Noam Lewit, James Stewart, Oluseyi Olawuyi, Mohammed A. Halim
Symposium of Student Scholars
Deep eutectic solvent(s) (DES) are the new generation of greener and more sustainable solvents, formulated by the complex of hydrogen bond in the molecules. The solvents allow us to achieve a significantly lower freezing point compared to its components, an affordable formulation and a technology that is typically formulated to improve the bioavailability of a drug. In this research project, we synthesized an ibuprofen-menthol based therapeutic deep eutectic solvent and investigated how water content affects the structure and dynamics of the solvent. For synthesizing the ibuprofen-menthol DES, 2.0629 g of Ibuprofen and 4.6881 g of menthol were placed in a …
Analysis Of Kavalactones In Various Consumptive Kava Samples Using Gc-Ms,
2021
Kennesaw State University
Analysis Of Kavalactones In Various Consumptive Kava Samples Using Gc-Ms, Stephanie O'Kon
Symposium of Student Scholars
Piper Methysticum, or Kava, is a plant native to the Pacific Islands and is used in various ceremonial and cultural aspects. In the United States, Kava has many dietary forms from sleep aids to mood boosters. The active ingredients found in Kava roots, kavalactones, give users psychoactive effects. However, there are concerns regarding toxicity and unknown safety consumption limits. There are six major kavalactones, and possibly more that have been reported, but not fully researched. The one of interest in this study is kavain. Different solvents, diethyl ether and acetone, have been used in extracting kavalactones from cut kava root. …
3-Dimensional Structural Determination Of Epidermal Growth Factor-Like Repeat 27 From Mouse Notch1 Using Nuclear Magnetic Resonance Spectroscopy,
2021
Louisiana State University
3-Dimensional Structural Determination Of Epidermal Growth Factor-Like Repeat 27 From Mouse Notch1 Using Nuclear Magnetic Resonance Spectroscopy, Justin Grennell
LSU Doctoral Dissertations
NOTCH1 has been associated with a variety of human ailments, such as cancer and heart disease. NOTCH1 is a transmembrane protein that contains 36 epidermal growth factor-like (EGF) repeats, which facilitate cell signaling by binding proteins on neighboring cells. Each repeat contains about 40 amino acids and has to be folded in a specific manner to function properly. The amino acid sequence, carbohydrate pattern, and calcium-binding sites of EGF-like repeats vary, but the pattern along the 36-repeat chain is conserved. The Abruptex region (EGF24-29) of NOTCH1 is a highly glycosylated (having undergone sugar addition) and flexible region, which gained its …
Investigating Thermodynamics And Kinetics Of Methylene Blue And Eriochrome Black-T Adsorption On Activated Carbon Prepared From Coconut Husk,
2021
College of Science, Hadhramout University
Investigating Thermodynamics And Kinetics Of Methylene Blue And Eriochrome Black-T Adsorption On Activated Carbon Prepared From Coconut Husk, Abdul Rahman Wahoud, Lotfi Abdul Samed Bawazer
Hadhramout University Journal of Natural & Applied Sciences
In this research, the adsorption process was studied for methylene blue eriochrome black-T from aqueous solutions on the surface of activated carbon prepared from coconut husk by chemical activation with potassium hydroxide. The results show that the adsorption isotherm for methylene blue follows the Langmuir model while it follows the Freundlich model and the maximum adsorption capacity was 909 mg/g for methylene blue and 262 mg/g for eriochrome black-T. The equilibrium contact time reached in about 90 minutes at lower concentrations and 120 minutes at higher concentrations. Two simplified kinetic models including pseudo-first-order and pseudo-second-order equations were selected to follow …
Kinetic, Equilibrium And Application Studies For Removal Of Methylene Blue From Aqueous Solution Using Sesbenia Dates Activated Carbon,
2021
College of Science, Hadhramout University
Kinetic, Equilibrium And Application Studies For Removal Of Methylene Blue From Aqueous Solution Using Sesbenia Dates Activated Carbon, Mohammed Saleh Bashanaini, Gameel Ahmed Baghaffar, Waheeb Abdellah Bin Frejan
Hadhramout University Journal of Natural & Applied Sciences
In the present work, sesbenia dates as local agricultural waste has been successfully used for the preparation of activated carbon (AC) by sulphuric acid. This sulphuric acid based activated carbon (SD) and (MSACS) were used for the removal of one cationic dye viz., methylene blue (MB) from aqueous solutions. The structure and physical and chemical properties of (SD) and (MSACS) are investigated using (FTIR) and (SEM) analysis and pH surface and Boehm titration. The effect of the differential experimental parameters controlling the adsorption of dye onto (SD) and (MSACS), were thoroughly investigated, such as the effect of pH, initial dye …
Mathematical Expression And Quantitative Analysis Of Impedance Spectrum On The Interface Of Glassy Carbon Electrode,
2021
State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Science, Guangxi Normal University, Guilin 541004, Guangxi, China;
Mathematical Expression And Quantitative Analysis Of Impedance Spectrum On The Interface Of Glassy Carbon Electrode, Lei Cheng, Pu-Xuan Yan, You-Jun Fan, Hua-Hong Zou, Hong Liang
Journal of Electrochemistry
Glassy carbon electrode (GCE) is a common basic electrode for various electrochemical sensors, and the detection properties are determined by its interfacial characteristics. In this paper, we established an equivalent circuit including electrolyte resistance (Rel), charge transport resistance (Rct), diffusion impedance (Rdi, Cdi), electrochemical (oxidation/reduction) reaction impedance (RR, CR), surface adsorption impedance (Rads , Cads), double-layer capacitance (CDL), and derived the mathematical expression for the equivalent circuit. The Rel and CDL are contributed by inactive …
Preparation Of Modified Titanium Based Pbo2 Electrode And Its Rapid Detection Of Cod,
2021
1. Department of Environmental Engineering, Beijing Institute of Petrochemical Technology, Beijing 102617, China;2. School of Environmental and Energy Engineering, Beijing University of Technology, Beijing 100124, China;
Preparation Of Modified Titanium Based Pbo2 Electrode And Its Rapid Detection Of Cod, Qi Sun, Yan-He Han, Xiao-Lu Fu
Journal of Electrochemistry
In the traditional Ti/β-PbO2 electrode, the crystal lattice difference between β-PbO2 and Ti matrix is large, and the prepared electrode is easy to fall off and has a short service life. It needs to be modified in actual use. Based on the advantages of α-PbO2 material and Ag material in terms of adhesion and conductivity, respectively, the above two materials are selected as the intermediate layer of Ti/β-PbO2 electrode to improve electrode performance. In this paper, by preparing Ti/α/β-PbO2 and Ti/Ag/β-PbO2 electrodes …
Fundamentals Of Electrochemical Impedance Spectroscopy For Macrohomogeneous Porous Electrodes,
2021
1. Shanxi Key Laboratory of Nanomaterials and Nanotechnology, Xi’an University of Architecture and Technology, Xi’an 710055, Shaanxi, China;
Fundamentals Of Electrochemical Impedance Spectroscopy For Macrohomogeneous Porous Electrodes, Xiang Li, Qiu-An Huang, Wei-Heng Li, Yu-Xuan Bai, Jia Wang, Yang Liu, Yu-Feng Zhao, Juan Wang, Jiu-Jun Zhang
Journal of Electrochemistry
Electrochemical impedance spectroscopy (EIS) can be used to diagnose charge transfer reactions and mass transport in porous electrodes. The charge transfer reactions include interfacial charge accumulation and charge conduction as well as electrochemical reaction. In this paper, the complex phasor method is developed under the macrohomogeneous assumption to build an impedance model of porous electrodes for clarifying several vague expressions in the traditional approaches. The following researches are carried out: (1) Identifying characteristic parameters for the porous electrodes, including electrode electronic conductivity σ1, electrolyte ionic conductivity σ2, interface charge transfer conductivity gct, unit area …
Bioadhesives,
2021
Lincoln , NE
Bioadhesives, Mark Alan Helle, Chin Li Cheung
Department of Chemistry: Faculty Publications
Materials and methods for preparing reactive lignin and for preparing a bio - based adhesive are described herein.
Lateral Growth Of Xenon Hydrate Films On Mica,
2021
University of Nebraska - Lincoln
Lateral Growth Of Xenon Hydrate Films On Mica, Avinash Kumar Both, Chin Li Cheung
Department of Chemistry: Faculty Publications
In this paper, we report an in situ optical microscopy study of lateral growth of xenon (Xe) hydrate thin films on mica at sub-zero temperatures. The interactions between a solid surface and water molecules can strongly affect the alignment of water molecules and induce ice-like ordered structures within the water layer at the water-surface interface. Mica was chosen as a model surface to study the surface effect of hydrophilic sheet silicates on the lateral growth of Xe hydrate films. Under the experimental conditions, the lateral growth of Xe hydrate films was measured to be at an average rapid rate of …
Comparison Of Design Approaches For Low-Cost Sampling Mechanisms In Open-Source Chemical Instrumentation,
2021
Rowan University
Comparison Of Design Approaches For Low-Cost Sampling Mechanisms In Open-Source Chemical Instrumentation, Greggory Murray, Samuel Bednarski, Michael Hall, Samuel W. Foster, Sijun Jin, Joshua J. Davis, Wei Xue, Eric Constans, James P. Grinias
College of Science & Mathematics Departmental Research
Robotic positioning systems are used in a variety of chemical instruments, primarily for liquid handling purposes, such as autosamplers from vials or well plates. Here, two approaches to the design of open-source autosampler positioning systems for use with 96-well plates are described and compared. The first system, a 3-axis design similar to many low-cost 3D printers that are available on the market, is constructed using an aluminum frame and stepper motors. The other system relies upon a series of 3D printed parts to achieve movement with a series of linker arms based on Selective Compliance Assembly Robot Arm (SCARA) design …
