Pharmacy and Pharmaceutical Sciences Commons^™

Antimicrobial Resistance In Pediatric Infections: Current Status, Challenges, And Future Directions, Clare Dinh, Keykavous Parang

Pharmacy Faculty Articles and Research

Background/Objectives: Antimicrobial resistance in pediatric infections presents a worsening global public health challenge, with antimicrobial resistance (AMR) accounting for more than one million deaths annually and disproportionately affecting children younger than 5 years of age. Neonates and critically ill children face heightened risk owing to immature immunity, frequent healthcare exposures, and limited therapeutic options. This review synthesizes evidence on the epidemiology, mechanisms of resistance, clinical outcomes, and management of AMR across the full pediatric age range. Methods: PubMed/MEDLINE and Google Scholar were searched for literature from 2014 to 2026 using terms covering antibiotic resistance, pediatric populations, and key …

Comparative Effectiveness Of Olmesartan Medoxomil In Monotherapy And Combination Therapy With Other Arb Medications: Literature Review, Deepika Saini

University Honors Theses

Hypertension remains one of the leading health issues; however, the awareness and control remain limited, with approximately 1.4 billion people affected by hypertension, yet only one in five has the condition effectively controlled. Despite the availability of effective treatments, knowledge and awareness remain limited. Angiotensin II receptor blockers (ARBs) are widely used antihypertensive medications because of their efficacy and safety profiles. Among these, Olmesartan Medoxomil has emerged as a prominent option, demonstrating strong efficacy in lowering blood pressure, both as monotherapy and in combination with other antihypertensive agents.

This thesis examines the comparative effectiveness of Olmesartan Medoxomil versus other ARBs …

Integrating Structural Analysis In The Pre-Appe Curriculum: Experiences From Three Institutions, Jennifer Ko, Sharon E. Connor, Emily K. Frederick, Katherine Foley, Emiline Snook, Ava Romah, Katie F. Leslie

Pharmacy Faculty Articles and Research

Background

Educational activity

Evaluation findings

Impact Of Dolutegravir-Based Regimens On Patient Satisfaction And Quality Of Life Among People Living With Hiv: A Systematic Review And Meta-Analysis, Mustapha Muhammed Abubakar, Christabel Ogechukwu Okoye, Ruth Jeminiwa, Ifeanyi Kanayo Ifeorah, Lotanna Ezeja, Yusuf Dauran, Sahabi Musa, Silas Usen Joel, Abdurrahman Murtala Bello, Amauche Pearl Ngige, Gabriel Ezenri, Abdulmuminu Isah, Ifunanya Ikhile, Blessing Onyinye Ukoha-Kalu

College of Pharmacy Faculty Papers

Background: Despite the global scale up of dolutegravir (DTG)-based regimens as the preferred first-line therapy for persons living with HIV (PLHIV), no comprehensive evidence exists on its effect on patient-reported outcomes such as Quality of Life (QoL) and patient satisfaction (PS). We conducted a systematic review and meta-analysis to provide the first comprehensive quantitative synthesis of the effect of DTG-based regimens on QoL and PS among PLHIV.

Method: We conducted literature search on PubMed, Scopus, Embase and Cochrane Library databases for peer-reviewed, primary studies published from January 2015 to January 2025. Studies using validated tools to evaluate QoL and PS …

An Exploratory Study: The Presence Of Imposter Syndrome In New Graduate Allied Health Professionals And Its Relationship To Location Of Practice, Samantha J. Barber, Carol A. Flavell Dr, Moira Smith Dr

Internet Journal of Allied Health Sciences and Practice

Purpose: Imposter syndrome (IS) explores the feelings of fraudulence within personal and professional settings. Commonly IS results in impaired self-confidence, and self-perceptions of one’s own abilities, their mental health, and places them at a higher risk of burnout. Imposterism is linked to transitionary periods, such as being newly graduated, and while IS addressed amongst the medical community [doctors and nurses], there is a gap in literature relating to IS amongst allied health professionals (AHPs). Additionally, there is no known literature in which IS presence or severity is explored in relation to an individual’s geographic location. The aim of this study …

Reality Check: Examining Perceived Stress In Student Pharmacists Using Virtual Reality, Kimberly B. Garza, Channing R. Ford, Kristen L. Helms

The Journal of Advancing Education Practice

The impact of stress on learning is complex and multifaceted, and there is a balance between stress that promotes learning and that which inhibits it. This study presents a qualitative analysis of students’ responses to a questionnaire about their experience using virtual reality (VR) in a perspective-taking task to promote empathy for patients with physical limitations due to arthritis of the hands. Including data collected from a first-year course in 2023, 2024, and 2025, 214 students ranked their stress while experiencing the task, and those who ranked stress as anything other than “no stress” were asked to elaborate on the …

Investigation Of Warfarin–Human Serum Albumin Binding By Ultrafast Affinity Extraction Using Single- And Dual-Column Affinity Microcolumn Systems, Samiul Alim

Department of Chemistry: Dissertations, Theses, and Student Research

This dissertation examined the interaction of warfarin with human serum albumin (HSA) by using affinity chromatography, with particular emphasis on ultrafast affinity extraction (UAE) and affinity microcolumns. HSA affinity supports were prepared by immobilizing HSA onto diol-bonded silica via Schiff base chemistry and used to prepare affinity microcolumns for chromatographic studies under physiological-like conditions at pH 7.4 and 37.0 °C. UAE studies were performed to investigate the effects of residence time, flow rate, and column configuration on the measured apparent free fraction of warfarin and on the calculated apparent binding parameters. The results showed that the measured apparent free fraction …

Evaluation Of The Impact Of Pharmacist-Led Toc On Patient Care Outcomes, Taabris Jaamal, Hana Breeland, Thanh Nguyen, Barbara Branneman, Jack Huber, Hung Phan

All Poster Presentations

No abstract provided.

The Impact On Nurses' Knowledge And Confidence Of Simulation With Chimeric Antigen Receptor T-Cell Infusion, Rachael Crickman, Shannon Williams, Heather Bissmeyer, Frances Chu, Cara Gallegos

All Poster Presentations

No abstract provided.

Evaluating Low Molecular Weight Heparin For Venous Thromboembolism Treatment In Extreme Body Weights, Natalie Tran, Brittanii Prahl, Jordan Amaro, Barbara Branneman, Jack Huber

All Poster Presentations

No abstract provided.

Euglycemic Diabetic Ketoacidosis: Institutional Review And Protocol Development, Lim Kang, Jordan Amaro, Brittanii Prahl, Jack Huber

All Poster Presentations

No abstract provided.

Comparable Endogenous Immune Reconstitution, Car-T Expansion, And Cytokine Profiles With Bendamustine Versus Fludarabine/Cyclophosphamide Lymphodepletion, Matthew Schwede, Sarah Hawley, Zachary Reitz, Faith Kierney, Neil Bailey, Tenzin Tsomo, Laiken Lopez, Terry Gilbertson, Christopher A Carney, Doug Kieper, Kelly Paulson, Krish Patel

All Poster Presentations

No abstract provided.

Beyond Ce Credit: A Retrospective Analysis Of Cme And Cpe Impact In A Health System, Diem Pham, Michelle Eng, Brandon Wu

All Poster Presentations

No abstract provided.

Assessment Of Patients With Newly Scheduled Opioids And Inappropriate Bowel Regimen, Melody Kazemini, Ryan Dow, Brittanii Prahl, Barbara Branneman, Jack Huber

All Poster Presentations

No abstract provided.

Thromboembolic Outcomes In Patients Receiving Doacs With Concomitant Antiseizure Medication, Hermela Gebregiogris, Brittanii Prahl, Michael Schirmer, Barbara Branneman, Jack Huber, Lam Vo

All Poster Presentations

No abstract provided.

Comparative Analysis Of Emergency Department Pain Medications Given For Treatment Of Sickle Cell Pain Crisis, Christo Mitchell, Kristian Campbell, Brittanii Prahl, Jack Huber

All Poster Presentations

No abstract provided.

June 2026, Swosu Rural Health Center

RURAL ROCKS

Rural Rocks

Second Generation Antipsychotics in the Treatment of Depression

Dr. Debra L. Stevens, Pharm.D., BCPP 

Major depressive disorder (MDD), also known as depression, affects 1 in 5 individuals in their lifetime.¹ Worldwide approximately 246 to 286 million individuals are afflicted with MDD.² MDD may cause significant morbidity and disability. The World Health Organization estimates that MDD will be one of the leading causes of disease burden by 2030.²

A significant number of patients diagnosed with MDD do not respond adequately despite appropriate treatment with antidepressants.² Treatment resistance may occur in up to one-third of patients …

Pacific Rxtracts - June 2026, Pacific Rxtracts

Pacific RxTracts

Articles:

• FDA Approves First Non-Antipsychotic Drug for Patients with Alzheimer’s Disease Agitation
• FDA Approves Sparsentan for Focal Segmental Glomerulosclerosis
• Lunsotogene Rings in a New Era of Gene Therapy for Hearing Loss
• Sex Differences in Breakthrough Stroke Outcomes Despite Oral Anticoagulation for Atrial Fibrillation
• Asundexian for Secondary Prevention After Ischemic Stroke or TIA
• Marstacimab Prophylaxis in Hemophilia A/B with Inhibitors: A New Purpose
• FDA Approves First-in-Class Weekly Anifrolumab Autoinjector for Systemic Lupus Erythematosus 
• Cemdisiran in Generalized Myasthenia Gravis
• Medicare’s Impact on Early Sepsis Management and Discharge to Home
• Maralixibat Shows Broader Therapeutic Benefit for Children with Alagille Syndrome 
• Reaching the Littlest …

Comparative Analysis Of Fixed Versus Variable Rate Of Regional Citrate Anticoagulation In Critically Ill Ecmo Patients On Continuous Kidney Replacement Therapy, Lisa Hall Zimmerman, Alexander Chen, Felcia Ivascu, Anthony Iacco, Jimmi Mangla, Wesley Barnes, Sean Masters

Conference Presentation Abstracts

Background: Continuous kidney replacement therapy (CKRT) is the preferred dialysis modality for critically ill patients with hemodynamic instability. Anticoagulation is often necessary to deliver CKRT effectively and prolong the circuit lifespan. The Kidney Disease Improving Global Outcomes (KDIGO) clinical practice guideline for acute kidney injury 2012 recommends regional citrate administration during CKRT for patients without contraindications to prevent filter clotting. Citrate works by chelating calcium and interfering with the activation of the coagulation cascade. This study evaluated effectiveness and safety of fixed (FIX) versus variable citrate rate (VAR) in critically ill patients receiving CKRT. Methods: This single-center, retrospective study evaluated …

Rocatinlimab As A Novel Treatment Strategy For Atopic Dermatitis, Haylee Whyde, Evan Blazek, Macy Davis, Parker George, Alex Lowery, Connor Dains, Brenna Hissong, David Koh

Pharmacy and Wellness Review

Atopic dermatitis is a common chronic inflammatory skin disease that affects millions of children and adults in the United States. Atopic dermatitis is characterized by recurrent pruritus, erythema, and relapsing symptoms that can significantly impair quality of life. The pathophysiology of atopic dermatitis involves epidermal barrier dysfunction, immune dysregulation, and genetic susceptibility. Atopic dermatitis guidelines follow a stepwise approach that begins with a severity assessment, trigger avoidance, and nonpharmacologic and pharmacologic treatments. First-line therapies include topical corticosteroids (TCSs), topical calcineurin inhibitors (TCIs), and emollients. Crisaborole and topical ruxolitinib are used for mild-to-moderate disease when prior therapy has been inadequate. Monoclonal …