Adherence To Malaria Treatment And Its Associated Factors: A Narrative Review,
2026
Master Program of Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran
Adherence To Malaria Treatment And Its Associated Factors: A Narrative Review, Lafie Urwatul Wutsqo, Eli Halimah, Sofa Dewi Alfian
Pharmacology and Clinical Pharmacy Research
Malaria is an infectious disease that remains a global health concern, particularly in Asia and Africa. The success of malaria medication largely depends on patients' adherence to the prescribed therapeutic regimen. This article aims to identify the level of adherence to malaria treatment and the factors that influence it, based on observational studies. A narrative review was conducted using the PRISMA approach, involving 12 articles published between 2019 - 2023 from various countries. The results indicate that adherence levels vary widely, ranging from 15.6% to 93.31%, depending on respondent characteristics and the intervention strategies implemented. Factors influencing adherence include patient-related …
Evaluation Of Drug Use In Inpatient Care: A Retrospective Study At A Tertiary Hospital In Bandung, Indonesia (2024),
2026
Pharmacist Professional Program, Faculty of Pharmacy, Universitas Padjadjaran, West Java, Indonesia 45363
Evaluation Of Drug Use In Inpatient Care: A Retrospective Study At A Tertiary Hospital In Bandung, Indonesia (2024), Aliya Rosyidah Fitrianti, Athoya Delarosa, Husna Muharram Ahadi, Imam Adi Wicaksono, Falerina Puspita
Pharmacology and Clinical Pharmacy Research
Rational drug use is a critical component of improving healthcare quality. However, irrational prescribing remains a significant concern, particularly in developing countries like Indonesia. This study evaluates drug use patterns at a Type B hospital in Bandung using WHO standard: average number of drugs per prescription, percentage of generic drugs, antibiotics, injections, and adherence to the National Formulary. A retrospective, descriptive observational method was applied, using 2024 inpatient Drug Use Evaluation (DUE) data. Findings reveal an average of 3.4 drugs per prescription—slightly above the WHO standard (≤ 3.3); 68.4% of prescriptions used generic drugs (meeting the WHO standard ≥ 59%); …
Comparison Of Chop And R-Chop For Treatment Non-Hodgkin Lymphoma, Yogyakarta, Indonesia: A Cost-Effectiveness Analysis,
2026
Faculty of Pharmacy, Universitas Ahmad Dahlan, Yogyakarta 55166, Indonesia
Comparison Of Chop And R-Chop For Treatment Non-Hodgkin Lymphoma, Yogyakarta, Indonesia: A Cost-Effectiveness Analysis, Woro Supadmi, Rizky Gustinanda, Lalu M. Irham, Riat El Khair
Pharmacology and Clinical Pharmacy Research
CHOP and R-CHOP are commonly used chemotherapy regimens for Non-Hodgkin Lymphoma (NHL). While R-CHOP has demonstrated clinical benefits, its higher cost raises concerns regarding economic efficiency, particularly in middle-income countries such as Indonesia. This study aimed to compare direct medical costs and clinical outcomes of CHOP and R-CHOP regimens among NHL patients treated at a national referral hospital in yogykarta. A retrospective cohort study was conducted using medical record data of NHL patients who received CHOP or R-CHOP chemotherapy at Dr. Sardjito General Hospital Yogyakarta, between 2020 and 2023, with follow-up extended until April 30, 2025. Clinical outcomes included overall …
Exploring Protein-Protein Interactions: A Promising Avenue For Biomarker And Anti-Tb Drug Development,
2026
Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang 45363, Indonesia
Exploring Protein-Protein Interactions: A Promising Avenue For Biomarker And Anti-Tb Drug Development, Rajwa Dwifauza Suryanto, Maritsa Widati Aqila Rumawan, Imam Adi Wicaksono
Pharmacology and Clinical Pharmacy Research
In 2023, tuberculosis (TB) reached its highest incidence with 8.2 million new cases reported by the World Health Organization (WHO). The virulence of Mycobacterium tuberculosis (MTB) is strongly governed by protein-protein interactions (PPIs) that regulate essential processes such as cell wall biosynthesis, immune evasion, and persistence. This study aims to map and analyze the mechanisms of key PPIs in MTB using a scoping review approach. Data was retrieved from PubChem and related literature with the keyword ``PPIs Network TB''. Our findings highlight crucial PPI-driven mechanisms, including the role of DprE1/DprE2 in arabinogalactan synthesis, VapB4/VapC4 in stress response and self-toxicity, ESX-1 …
Low To Moderate Intensity Home-Based And Online Exercise For Cognitive Health In Older Adults: A Narrative Review,
2026
Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran AND Prodia Clinical Laboratory, Central Jakarta, Indonesia
Low To Moderate Intensity Home-Based And Online Exercise For Cognitive Health In Older Adults: A Narrative Review, Novita Salim, Melisa Intan Barliana, Anna Meiliana
Pharmacology and Clinical Pharmacy Research
Cognitive decline represents one of the most pressing public health challenges associated with global population ageing, prompting growing interest in accessible and scalable exercise-based interventions. This narrative review synthesizes evidence from 15 randomized controlled trials to compare the cognitive effects of 3 exercise modalities in older adults across varying cognitive and functional profiles: conventional aerobic and resistance training, exergame-based interventions, and dual-task or multicomponent training. Interventions were evaluated on their capacity to improve global cognition, executive function, working memory, and attention, with additional consideration of adherence, supervision format, and implementation feasibility. The evidence consistently demonstrates that dual-task and multicomponent training …
Patterns Of Adverse Drug Reactions In Tuberculosis Treatment: A Literature Review,
2026
Master of Pharmacoepidemiology and Pharmacoeconomics Program, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, Indonesia AND Center of Excellence for Pharmaceutical Care Innovation, Universitas Padjadjaran, Sumedang, Indonesia
Patterns Of Adverse Drug Reactions In Tuberculosis Treatment: A Literature Review, Jasmine R. Aisyah, Ivan S. Pradipta, Widya N. Insani
Pharmacology and Clinical Pharmacy Research
Tuberculosis (TB) treatment is often interrupted by adverse drug reactions (ADRs). However, few studies have thoroughly examined these ADR patterns in TB treatment, and no research has assessed the prevalence of ADRs in specific organs. This narrative review describes the patterns of ADRs in tuberculosis treatment, including how common each type is and its impact on organs across different countries and populations. A structured narrative literature review was conducted to identify relevant original studies published in PubMed database between 2019 and 2025. The search combined Medical Subject Headings (MeSH) and free-text terms related to ``tuberculosis'' and ``adverse drug reactions''. Eligible …
Evaluation Of The Compliance Of Ultra-Low Dose Drugs Available In Local Iraqi Markets With Regulatory Weight Variation Test,
2026
Department of Pharmaceutics, College of Pharmacy, University of Tikrit, Tikrit, Iraq
Evaluation Of The Compliance Of Ultra-Low Dose Drugs Available In Local Iraqi Markets With Regulatory Weight Variation Test, Yousif K. Younis
Al-Mustaqbal Journal of Pharmaceutical and Medical Sciences
Mixing and formulation of drugs with very low dose is a brutal challenge to formulators sometimes due to all kinds of difficulties like segregation, content uniformity and physicochemical stability issues. A careful consideration of all related factors is essential during manufacturing of very low dose drug products. The aim of this study is to evaluate the quality control of ultra-low dose drugs of different companies available in local Iraqi and their compliance with regulatory weight variation test. Quantitative analysis conducted to five drugs using weight variation technique with 20 randomly selected tablets for each drug. All of these drugs passed …
A Comparative Study Examining The Effects Of Nifedipine And Minoxidil On Stimulating Hair Growth Using A Mouse Model,
2026
Tikrit University- College of Pharmacy- Tikrit- Iraq
A Comparative Study Examining The Effects Of Nifedipine And Minoxidil On Stimulating Hair Growth Using A Mouse Model, Nihad Hussein Ahmed, Rabei Abdullah Salih, Shereen M. Mekkey
Al-Mustaqbal Journal of Pharmaceutical and Medical Sciences
Hair loss is a common human scalp condition caused by chemotherapy, chronic diseases, and aging. Currently, it is estimated that approximately 50% of males and 15–30% of females experience hair loss issues. Minoxidil is considered a preferred treatment for hair loss in men and women. Nifedipine is effective in improving blood circulation and blood supply via its vasodilator action. To compare nifedipine and minoxidil in terms of their effect on stimulating hair growth using a mouse model. Fifteen female albino mice, aged 8 to 10 weeks, were randomly assigned to three groups of five mice each, all with shaved dorsal …
Buccal Films As An Emerging Drug Delivery System: A Comprehensive Review,
2026
Department of Pharmaceutics, Vidyabharati College of Pharmacy, Amravati, India
Buccal Films As An Emerging Drug Delivery System: A Comprehensive Review, Syed Faizan Syed Nizamuddin, Nishan N. Bobade, Vikrant P. Wankhade, Sandeep C. Atram, Shrikant D. Pande, Nakul S. Dhore, Shraddha P. Malpani, Ashwin A. Pahurkar
Al-Mustaqbal Journal of Pharmaceutical and Medical Sciences
Oral administration through the digestive tract is still the most common means by which drugs are given, as it is simple and cheap. However, it has some biopharmaceutical limitations in general, such as varying gastrointestinal conditions, enzymatic degradation, and extensive hepatic first-pass metabolism, which decrease drug stability and bioavailability To address these challenges, drug delivery through the oral mucosa (OMDD) has emerged as a potential non-invasive option. The buccal mucosa is well supplied with blood, provides a relatively mild environment, and avoids hepatic first-pass metabolism, thereby resulting in a faster onset of action and improved bioavailability. Mucoadhesive buccal films have …
Ethnopharmacology, Phytochemistry, And Pharmacological Potential Of Philenoptera Laxiflora: An Emerging African Medicinal Plant For Drug Discovery,
2026
Department of Pharmacology, Faculty of Basic Medical Sciences, Sa'adu Zungur University, Bauchi State, Nigeria
Ethnopharmacology, Phytochemistry, And Pharmacological Potential Of Philenoptera Laxiflora: An Emerging African Medicinal Plant For Drug Discovery, Albashir Tahir
Al-Mustaqbal Journal of Pharmaceutical and Medical Sciences
Medicinal plants remain an important source of therapeutic agents and play a significant role in modern drug discovery. Philenoptera laxiflora (Fabaceae) is a tropical African plant widely used in traditional medicine, but the scientific evidence supporting its therapeutic potential remains fragmented. This review aims to comprehensively summarize the current knowledge on the ethnomedicinal uses, phytochemical composition, pharmacological activities, and toxicological profile of P. laxiflora, while highlighting research gaps and future directions for drug discovery. A comprehensive literature search was conducted using electronic scientific databases, including PubMed, Google Scholar, Scopus, Web of Science, and ScienceDirect. Relevant publications on the ethnobotany, …
Prevalence Of Medication Prescription Patterns For Iraqi Outpatients Visiting Otolaryngology Clinics,
2026
Department of Pharmacology and Toxicology, College of Pharmacy, University of Kirkuk, Kirkuk, Iraq, Ph.D. in Clinical Pharmacy
Prevalence Of Medication Prescription Patterns For Iraqi Outpatients Visiting Otolaryngology Clinics, Mirna. K. Faiq
Al-Mustaqbal Journal of Pharmaceutical and Medical Sciences
Objectives: To assess the prevalence of drug use patterns among ENT outpatient settings in Kirkuk, Iraq. Methods: This retrospective observational study was conducted in Kirkuk, Iraq, involving the collection of data from the e-Prescribing system and the review of written prescriptions, including 582 outpatient records from ENT clinics, from January 2024 to December 2024. Results: Most patients were below 20yr age (18.73%), with a male predominance (57%). Ear-related complaints like otitis media were the most frequent (35.22%). The average number of drugs per prescription was 2.82. The percentage of prescriptions in which an antibiotic was prescribed was 84.7%. The percentage …
Preparation And In-Vitro Evaluation Of Tizanidine Flash Oral Dispersible Tablet,
2026
College of Pharmacy, University of Tikrit, Tikrit, Iraq
Preparation And In-Vitro Evaluation Of Tizanidine Flash Oral Dispersible Tablet, Ahmed Yousif Fadhel, Yousif K. Younis
Al-Mustaqbal Journal of Pharmaceutical and Medical Sciences
Background: Oral administration is the most common and preferred route for drug delivery. Oral dispersible tablets (ODTs) are solid dosage forms that disintegrate into saliva without the need for water. Tizanidine is a centrally acting muscle relaxant used to manage spasticity from spinal or brain injuries. Preparing it as a flash (ODT) tablet may enhance patient compliance and potentially improve bioavailability by bypassing part of the first-pass metabolism. Methods: Six formulations of tizanidine flash tablets were developed using varying concentrations of mannitol (bulk-forming agent), glycine (to aid tablet collapse), and gelatin (matrix-forming agent). The formulations were evaluated for weight variation, …
Bioactive Constituents And Pharmacological Activities Of Curcuma Zedoaria: A Mini-Review,
2026
Faculty of Applied Sciences, Universiti Teknologi MARA, 40450 Shah Alam, Selangor Darul Ehsan, Malaysia AND Atta-ur-Rahman Institute for Natural Products Discovery (AuRIns), Universiti Teknologi MARA, Puncak Alam Campus, 42300 Puncak Alam, Selangor, Malaysia
Bioactive Constituents And Pharmacological Activities Of Curcuma Zedoaria: A Mini-Review, Abdulmutalib Allaq, Muneer M. Saleh Mohammed Saleh Alsayadi, Mustapha Salihu, Hasan M. Agha, Amena Hassan Hassan Gheeth, Fatimah Salim, Norrizah Jaafar Jaafar Sidik
AUIQ Complementary Biological System
Curcuma zedoaria Rosc. (white turmeric) is a rhizomatous medicinal plant in the Zingiberaceae family, widely used in traditional Asian medicine. In recent years, increasing scientific attention has focused on its diverse pharmacological properties and bioactive constituents. This mini review summarises current knowledge of the phytochemical composition and biological activities of C. zedoaria, with particular emphasis on its antimicrobial, antioxidant, anti-inflammatory, and anticancer effects. Phytochemical investigations using analytical techniques such as GC–MS and HPLC have revealed the presence of numerous bioactive compounds, including sesquiterpenes (example, germacrone, curzerenone, and curdione) and curcuminoids, which contribute to its therapeutic potential. Experimental studies demonstrate …
Raising The Barb: Evaluation Of Phenobarbital Use For Alcohol Withdrawal In Patients On General Medicine Floors,
2026
Providence
Raising The Barb: Evaluation Of Phenobarbital Use For Alcohol Withdrawal In Patients On General Medicine Floors, Seth Arakawa, Jason Frederick, Anthony Le
Books, Presentations, Posters, Etc.
Abstract: Alcohol withdrawal syndrome (AWS) can present as a spectrum of symptoms such as a mild headache, gastrointestinal issues, and diaphoresis. However, if not treated properly, it can progress to severe hallucinations, seizures, or delirium tremens. Current guidelines from the American Society of Addiction Medicine (ASAM) recommend benzodiazepines as first line agents for alcohol withdrawal with phenobarbital recommended as an adjunct agent or replacement to benzodiazepines by providers who are familiar with its use. Although most evidence supporting phenobarbital in AWS comes from critical care settings, emerging data suggest it may also be safe and effective in general ward patients. …
Score Data 2026,
2026
University of Mississippi
Score Data 2026, M. Barnard, T. Johnson, A. Ford-Wade, M. Godfrey, C. Compretta, E. Dehon, B. Wade
Faculty and Student Publications
This data file includes data for four years of Project SCORE implementation.
Coordinated Telehealth For People With Parkinson’S Disease: A Qualitative Comparison Of Providers’ And Patients’ Experiences,
2026
Florida State University, Communication Science and Disorders. Tallahassee, Florida, USA
Coordinated Telehealth For People With Parkinson’S Disease: A Qualitative Comparison Of Providers’ And Patients’ Experiences, Erin J. Bush, Reshmi L. Singh, Josephine Cox, Merrill R. Landers, Annalisa V. Piccorelli
The Qualitative Report
Telehealth increases access to allied healthcare in rural areas. People with Parkinson’s disease (PD) need improved access to health care, and from a patient-centered perspective, the coordination of their healthcare should be a priority. Four speech-language pathologists, two physical therapists, two pharmacists, and two study coordinators provided a coordinated allied healthcare intervention for people with PD in rural Wyoming and Nevada. Both the providers of the intervention, as well as the participants who received it, were interviewed about their experiences with the eight-week intervention and asked about aspects that were successful or unsuccessful. Through a naturalistic paradigm using a qualitative …
Behavioral Effects Of Cocaine After Activation Of Cb1 Cannabinoid Receptors In Male And Female Mice,
2026
ONU
Behavioral Effects Of Cocaine After Activation Of Cb1 Cannabinoid Receptors In Male And Female Mice, Cade Baughman, Jejun Lee, Jessica Acheampong, Jihoon Choi, Sarah Seeley, Manoranjan Dsouza
ONU Student Research Colloquium
The goal of this study was to assess the behavioral effects of cocaine following activation of CB1 cannabinoid receptors in male and female mice. This study was undertaken because recently published data suggest sex-dependent behavioral differences after CB1 receptor activation. However, the sex-dependent effects of CB1 receptor activation on the rewarding and psychomotor effects of cocaine have not been systematically evaluated. This study aimed to address this gap in knowledge. The study will use adult male and female C57BL6 mice. CB1 receptors will be activated using synthetic cannabinoid WIN 55212. Behavioral effects assessed after CB1 receptor activation will include both …
A Single Administration Of Psilocybin Is Ineffective In Reversing Ptsd-Like Sequelae In A Rat Model Of Stress-Enhanced Fear Learning,
2026
Ohio Northern University
A Single Administration Of Psilocybin Is Ineffective In Reversing Ptsd-Like Sequelae In A Rat Model Of Stress-Enhanced Fear Learning, Kylie M. King, Marisa J. Savini, Noelle M. Molnar, Evelynn J. Schneider, Savannah E. Straub, Joe Parker, Lillianna P. Puppel, Aleece K. Al-Olimat, Allison M. Bach, Phillip R. Zoladz
ONU Student Research Colloquium
Single treatments with psychedelics produce rapid, long-lasting antidepressant effects. Psychedelics may also exert anxiolytic effects and be useful in treating more complex psychiatric conditions, such as PTSD. However, less is known about the impact of these agents on PTSD-related symptoms. Thus, we aimed to determine whether a single administration of psilocybin could reverse PTSD-like sequelae induced by stress-enhanced fear learning in rats. Sprague-Dawley rats were placed in Context A (circular, white conditioning box) and exposed to several uncontrollable footshocks (Stress) or no footshocks (No Stress). The next day, the rats were placed in Context B (square conditioning box with clear …
Psilocybin And The Related Tryptamine, Norbaeocystin, Exert Acute Anxiogenic Effects That Depend On Sex,
2026
Ohio Northern University
Psilocybin And The Related Tryptamine, Norbaeocystin, Exert Acute Anxiogenic Effects That Depend On Sex, Marisa J. Savini, Kylie M. King, Noelle M. Molnar, Evelynn J. Schneider, Savannah E. Straub, Joe Parker, Lillianna P. Puppel, Aleece K. Al-Olimat, Allison M. Bach, Andrew Jones, Phillip R. Zoladz
ONU Student Research Colloquium
Single treatments with psychedelics have demonstrated rapid, long-lasting antidepressant effects. However, psychedelics often produce unfavorable psychoactive effects that could worsen existing psychological distress. Thus, we compared the effects of psilocybin and the related tryptamine, norbaeocystin, on anxiety-like behavior in male and female rats. In Experiment 1, rats were treated with 1 mg/kg psilocybin (PSIL), 1 mg/kg norbaeocystin (NOR), or vehicle 30 min before a 5-min trial on an elevated plus maze (EPM) or in an open field test (OFT). On the EPM, PSIL led to decreased open arm time and fewer arm entries in males and females. NOR led to …
How To Best Utilize Outcomesmtm In Patient Care Settings,
2026
Ohio Northern University
How To Best Utilize Outcomesmtm In Patient Care Settings, Anna Spalvieri
ONU Student Research Colloquium
Pharmacies are essential for the reception and filling of prescriptions, but they can also be vital for the monitoring and managing of different patient conditions and medication regimens. Patients, especially those who are older or live with chronic conditions, can be prescribed many different medications and therapies. Inversely, they might not have the medications and therapies needed to address their conditions. ONU Healthwise Pharmacy and the pharmacy call center utilize a platform called OutcomesMTM as a way of providing Medication Therapy Management (MTM) services to help patients control their chronic conditions and manage their health. These services, delivered through phone …
