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Articles 4471 - 4500 of 62458

Full-Text Articles in Public Affairs, Public Policy and Public Administration

A Call To Action For Transport Justice: Exploring Transportation Disadvantages Faced By Justice-Impacted Individuals Reintegrating Into Rural Communities, Tarnika Edmunds Jan 2025

A Call To Action For Transport Justice: Exploring Transportation Disadvantages Faced By Justice-Impacted Individuals Reintegrating Into Rural Communities, Tarnika Edmunds

Master of Urban and Regional Planning Capstone Projects

This study explores the intersection of rural reentry and transportation planning, emphasizing the importance of Transport Justice in overcoming barriers faced by transit-dependent populations, particularly formerly incarcerated individuals. While urban transportation planning is widely discussed, this research highlights the overlooked challenges that rural environments pose for individuals reentering society. Through a multi-method approach that involved document analysis, participant observations, and informal discussions, this study uncovers a range of themes related to accessibility, reliability, vulnerability, and the quality of commuting experiences. The findings underline the necessity for transparency, accountability, and collaboration across sectors to address these gaps and inform policies that …


Exploring The Role Of Government Funding And Policy Criteria In Greening Projects: A Case Study Of Southside Richmond, Destiny R. Brown Jan 2025

Exploring The Role Of Government Funding And Policy Criteria In Greening Projects: A Case Study Of Southside Richmond, Destiny R. Brown

Master of Urban and Regional Planning Capstone Projects

This thesis explores how government and private funding structures and policy criteria influence community-based organizations (CBOs) engaged in urban greening projects, focusing on Southside Richmond, Virginia through a case study of a local CBO. Using a multi-method approach including document analysis, secondary data review, and autoethnographic reflection, the research suggests a gap between visibility and influence for CBOs, showing that their decision-making authority often varies while they are publicly recognized. The study also reveals that public documentation of funders' community engagement is often performative or symbolic rather than structurally embedded in decision-making processes. In addition, funding remains a barrier, with …


Firelog: An Open-Source, Low-Cost System For Temperature Logging During Wildland Fires With High Spatial And Temporal Resolution, Nipuna Chamara, Yufeng Ge, Sabrina E. Russo Jan 2025

Firelog: An Open-Source, Low-Cost System For Temperature Logging During Wildland Fires With High Spatial And Temporal Resolution, Nipuna Chamara, Yufeng Ge, Sabrina E. Russo

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Measuring flame, air, and soil temperatures during wildland fires, including wildfires and controlled burns in land management contexts, is crucial for research and applications in fire ecology, safety, and management in a wide array of ecosystems, from grasslands to forests. However, open-source and commercial systems are needed for measuring and logging flame and air temperatures that are user-friendly, economical, modular, and customizable. This paper details the design, development, and validation of the FireLog system. Laboratory validation experiments demonstrated high measurement accuracy, with a minimum coefficient of determination (R2) of 0.98 and the highest observed root mean square error (RMSE) of …


Transforming Urban Dynamics: Harnessing Large Language Models For Smarter Mobility, Hao Xue, Ming Jin, Shirui Pan, Flora Salim, Guansong Pang Jan 2025

Transforming Urban Dynamics: Harnessing Large Language Models For Smarter Mobility, Hao Xue, Ming Jin, Shirui Pan, Flora Salim, Guansong Pang

Research Collection School Of Computing and Information Systems

Artificial intelligence (AI) has the potential to analyze mobility data and make mobility systems smarter by leveraging diverse data sources such as geospatial data, transportation logs, and real-time sensor data to optimize traffic flow, enhance public transportation systems, and support the development of autonomous vehicles. With the newly emerged generative AI paradigm, exemplified by large language models (LLMs), there is great potential to transform the current AI applications in mobility, transportation, and urban domains. This article provides an overview of recent efforts and aims to shed light on the challenges and future opportunities to facilitate the adaptation of LLMs for …


The Strategy Of Ikatan Motor Indonesia (Imi) In Building Organizational Branding Through The Indonesia International Motor Show (Iims) 2025, Mazaya Fathia Adreya Wibowo, Anisatul Auliya Jan 2025

The Strategy Of Ikatan Motor Indonesia (Imi) In Building Organizational Branding Through The Indonesia International Motor Show (Iims) 2025, Mazaya Fathia Adreya Wibowo, Anisatul Auliya

Journal of Indonesian Tourism and Policy Studies

Automotive industry is one of growing competitive industry, organisational branding is essential to shape public image and loyalty. This research aims to analyse the branding strategy of the Ikatan Motor Indonesia (IMI) through its participation in the Indonesia International Motor Show (IIMS) 2025. The research used a qualitative method with a case study approach. Data collection techniques were conducted through in-depth interviews, direct observation, literature study, and documentation. Data analysis used the Miles and Huberman model through collection, reduction, data presentation, and conclusion drawing and verification. The results showed that IMI successfully utilised the five main elements of branding according …


Implementation Of Standard Operating Procedures 'Cold Kitchen' In Food Storage Process At Hotel Indonesia Kempinski Jakarta, Alya Kamilianada Jan 2025

Implementation Of Standard Operating Procedures 'Cold Kitchen' In Food Storage Process At Hotel Indonesia Kempinski Jakarta, Alya Kamilianada

Journal of Indonesian Tourism and Policy Studies

The background of this study was conducted to find out how a kitchen must have SOP (Standard Operating Procedure), because the kitchen is very influential in supporting food management operations at Cold Kitchen Hotel Indonesia Kempinski Jakarta and to find out the system of storage procedures for perishable food ingredients has an important role as the main raw material in making types of menus in cold kitchens as a provider of various types of fruits and vegetables. The problem formulation consists of: (1) How to strive for the implementation of SOP (Standard Operating Procedures) in the process of storing foodstuffs …


The Role Of Interpersonal Communication With Clients In Supporting Work Effectiveness At Pt. Antavaya Tour & Travel, Dennisa Arofani Aurellia Jan 2025

The Role Of Interpersonal Communication With Clients In Supporting Work Effectiveness At Pt. Antavaya Tour & Travel, Dennisa Arofani Aurellia

Journal of Indonesian Tourism and Policy Studies

Humans are social creatures who cannot live without other people around us. Humans also need to communicate with each other in order to become a basic need to share information with each other. Communication is also used as a measure of the effectiveness of a job. Communication is also divided into several meanings, one of which is interpersonal communication. Interpersonal communication is also used in the document division at PT. Antavaya Tour & Travel to support work effectiveness. Generally, the document division of PT. Antavaya Tour & Travel acts as a provider and service provider for making travel documents. Therefore, …


The Overlooked Dynamics Of Sibling Violence: Sociological Perspectives And Intervention Strategies, Rowland Edet Jan 2025

The Overlooked Dynamics Of Sibling Violence: Sociological Perspectives And Intervention Strategies, Rowland Edet

Department of Sociology: Faculty Publications

Sibling violence (SV) represents a pervasive yet underexplored dimension of family violence, encompassing physical, emotional, and psychological abuse. This paper critically examines the intersection of gender dynamics, societal norms, and family structures in shaping SV behaviors. Using social learning theory (SLT) as a foundational framework, the analysis explores how gendered expectations and traditional roles influence the prevalence and forms of aggression, with boys more likely to exhibit overt physical aggression and girls engaging in relational aggression. The paper critiques the deterministic tendencies of SLT, highlighting the agency of individuals in rejecting modeled behaviors, and incorporates intersectionality to address the interplay …


A Hybrid Cloud Data Lake Architecture Supporting The Integration Of Clinical And Genomics Data, Apollo Mcowiti, Heidi Dowst, Fei Zheng, Susan Hilsenbeck, Christopher Amos Jan 2025

A Hybrid Cloud Data Lake Architecture Supporting The Integration Of Clinical And Genomics Data, Apollo Mcowiti, Heidi Dowst, Fei Zheng, Susan Hilsenbeck, Christopher Amos

Center for Medical Ethics and Health Policy Staff Publications

Objective: Cancer centers must quickly integrate clinical genomics data from different vendors for oncology operations and research. Clinical data warehouse architectures are costly to construct and brittle, and they are not readily amenable to the rapid changes in oncology research. We introduce a cost-effective hybrid cloud Data Lake architecture for storing clinical genomic data from different vendors, aiding both clinical and research workflows.

Methods: We created a Data Lake architecture based on the zone architecture, with four layers: ingestion, storage, transformation, and interaction. The layers are implemented with a hybrid cloud architecture. Rich metadata created from patient and genomic data …


Transit-Oriented Development On Aquidneck Island: Considering The Costs And Benefits Of Restoring Passenger Rail Between Fall River, Massachusetts, And Newport, Rhode Island, Maeve M. Newton Jan 2025

Transit-Oriented Development On Aquidneck Island: Considering The Costs And Benefits Of Restoring Passenger Rail Between Fall River, Massachusetts, And Newport, Rhode Island, Maeve M. Newton

Pell Scholars and Senior Theses

This thesis considers the costs and benefits of restoring historic infrastructure as transit-oriented development on Aquidneck Island, and its potential to bridge social and economic gaps between the urban communities of Newport, Rhode Island, and Fall River, Massachusetts. There is a direct need for more robust public transportation on Aquidneck Island along with environmentally friendly planning initiatives, and reinstating the Newport Secondary Rail Line for passenger rail service to the new Fall River MBTA station is one important way for historic preservation to be utilized for the improvement of sustainability and socioeconomic equity in the region. Original research will be …


America’S Hidden Heroine: The Revolutionary Experience Of Deborah Sampson, Rebecca A. Dawson Jan 2025

America’S Hidden Heroine: The Revolutionary Experience Of Deborah Sampson, Rebecca A. Dawson

Pell Scholars and Senior Theses

This thesis explores the life of Deborah Sampson, a female soldier in the Fourth Massachusetts Regiment during the American Revolution. The author discusses how and why Sampson joined the military, the challenges she had to overcome, and her experience as the first American woman to lead a public lecture tour. Sampson continues to serve as an embodiment of resilience, courage, and the Spirit of ‘76.


Investigative Genetic Genealogy Practices Warranting Policy Attention: Results Of A Modified Policy Delphi, Christi J Guerrini, Louiza Kalokairinou, Jill O Robinson, Whitney Bash Brooks, Stephanie M Fullerton, Sara Huston, Jacklyn Dahlquist, Diana Madden, Norah Crossnohere, Nicola Campoamor, John F P Bridges, Amy L Mcguire Jan 2025

Investigative Genetic Genealogy Practices Warranting Policy Attention: Results Of A Modified Policy Delphi, Christi J Guerrini, Louiza Kalokairinou, Jill O Robinson, Whitney Bash Brooks, Stephanie M Fullerton, Sara Huston, Jacklyn Dahlquist, Diana Madden, Norah Crossnohere, Nicola Campoamor, John F P Bridges, Amy L Mcguire

Center for Medical Ethics and Health Policy Staff Publications

A technique known as investigative genetic genealogy (IGG) was first introduced to criminal investigations in 2018, and it has since been used by U.S. law enforcement to help identify hundreds of criminal perpetrators and unidentified human remains. As expertise in IGG grows, policymakers have shown interest in regulating it. To help inform these efforts and to promote coherence in IGG governance as it expands, we recruited experts representing a spectrum of IGG-relevant professions and perspectives to identify and prioritize IGG practices for policy attention and to develop policy options for addressing them. In two rounds of a modified policy Delphi, …


Survivorship From Pediatric And Adult Brain Tumors: The 2024 Brain Tumor Epidemiology Consortium Meeting Report, Scott L Coven, Roberta Mckean-Cowdin, Michael E Scheurer, Kimberly J Johnson, Luc Bauchet, Carol Kruchko, Ching C Lau, Quinn T Ostrom, John Villano, Yan Yuan, Friederike Erdmann Jan 2025

Survivorship From Pediatric And Adult Brain Tumors: The 2024 Brain Tumor Epidemiology Consortium Meeting Report, Scott L Coven, Roberta Mckean-Cowdin, Michael E Scheurer, Kimberly J Johnson, Luc Bauchet, Carol Kruchko, Ching C Lau, Quinn T Ostrom, John Villano, Yan Yuan, Friederike Erdmann

Center for Medical Ethics and Health Policy Staff Publications

The Brain Tumor Epidemiology Consortium (BTEC) is an international organization with membership of individuals from the scientific community with interests related to brain tumor epidemiology, including surveillance, classification, methodology, etiology, and factors associated with morbidity and survival. The 2024 annual BTEC meeting entitled “Survivorship from Pediatric and Adult Brain Tumors” was held in Mainz, Germany, USA, on May 15–17, 2024. The meeting gathered scientists from Africa, Australia, Europe, and North America and included 4 keynote sessions focusing on brain tumor survivorship across the age spectrum. The meeting included 3 abstract sessions, which also included scientific talks around brain …


On Minimizing Risk And Harm In The Use Of Psychedelics, Jules Evans, Marc Aixalà, Brian T Anderson, William Brennan, Rebecka Bremler, Joost J Breeksema, Lisa Burback, Abigail E Calder, Robin L Carhart-Harris, Katherine Cheung, Neşe Devenot, Ingmar Gorman, Jakub Greń, Peter S Hendricks, Brian Holoyda, Edward Jacobs, Joy Krecké, Daniel J Kruger, David Luke, Tomislav Majić, Amy L Mcguire, Nicky J Mehtani, David S Mathai, Kristin Nash, Tehseen Noorani, Roman Palitsky, Oliver C Robinson, Otto Simonsson, Elin Stahre, Michiel Van Elk, David B Yaden Jan 2025

On Minimizing Risk And Harm In The Use Of Psychedelics, Jules Evans, Marc Aixalà, Brian T Anderson, William Brennan, Rebecka Bremler, Joost J Breeksema, Lisa Burback, Abigail E Calder, Robin L Carhart-Harris, Katherine Cheung, Neşe Devenot, Ingmar Gorman, Jakub Greń, Peter S Hendricks, Brian Holoyda, Edward Jacobs, Joy Krecké, Daniel J Kruger, David Luke, Tomislav Majić, Amy L Mcguire, Nicky J Mehtani, David S Mathai, Kristin Nash, Tehseen Noorani, Roman Palitsky, Oliver C Robinson, Otto Simonsson, Elin Stahre, Michiel Van Elk, David B Yaden

Center for Medical Ethics and Health Policy Staff Publications

Objective: This article outlines recommendations from 30 psychedelic researchers on how to create a better psychedelic safety net.

Methods: A survey of 30 psychedelic researchers asked them to identify key critical research gaps around psychedelic harm and safety.

Results: The critical research gaps identified by the authors included defining the main types of psychedelic harm, the predictors of those harms, and the most effective way to treat those harms. They also call for better support for those experiencing post-psychedelic difficulties, including better online information, peer support groups, affordable therapy, and psychiatric consultation and medication. Finally, the authors call for better …


When Families Bridge The Research-Clinical Divide: An Exploration Of Values Regarding Cascade Screening In Genomic Research, Katherine E Bonini, Lauren R Desrosiers-Battu, Ann Katherine M Foreman, Nuriye N Sahin-Hodoglugil, Mary A Majumder, Candice R Finnila, Stephanie A Kraft, Laura M Amendola, Eimear E Kenny, Stephanie M Fullerton, Sara L Ackerman, Benjamin S Wilfond, Amy L Mcguire, Hadley Stevens Smith Jan 2025

When Families Bridge The Research-Clinical Divide: An Exploration Of Values Regarding Cascade Screening In Genomic Research, Katherine E Bonini, Lauren R Desrosiers-Battu, Ann Katherine M Foreman, Nuriye N Sahin-Hodoglugil, Mary A Majumder, Candice R Finnila, Stephanie A Kraft, Laura M Amendola, Eimear E Kenny, Stephanie M Fullerton, Sara L Ackerman, Benjamin S Wilfond, Amy L Mcguire, Hadley Stevens Smith

Center for Medical Ethics and Health Policy Staff Publications

Purpose: Genetic results are important for both patients and their biological relatives. However, cascade screening (CS) uptake is low, especially when testing occurs through research programs and not clinical care. Ethical guidance is needed for CS implementation when individuals receive clinical genetic results through research.

Methods: We conducted focus groups with 3 groups of individuals in the Clinical Sequencing Evidence-Generating Research Consortium: clinicians, patient representatives, and scholars of the ethical, legal, and social implications of genomics. We used inductive thematic and comparative analyses to analyze data within and across the groups.

Results: All participants (n = 27) agreed that …


Methadone For Critically Ill Patients Under Mechanical Ventilation In The Intensive Care Unit: A Systematic Review, Sérgio Martins Pereira, Megan Abbott, João Francisco Figueiredo Marcondes Ferraz, Akash Goel, Andrea Rigamonti, Charmaine De Castro, Lisa Burry, Airton Leonardo De Oliveira Manoel, Michael Chaim Sklar Jan 2025

Methadone For Critically Ill Patients Under Mechanical Ventilation In The Intensive Care Unit: A Systematic Review, Sérgio Martins Pereira, Megan Abbott, João Francisco Figueiredo Marcondes Ferraz, Akash Goel, Andrea Rigamonti, Charmaine De Castro, Lisa Burry, Airton Leonardo De Oliveira Manoel, Michael Chaim Sklar

Center for Medical Ethics and Health Policy Staff Publications

Purpose: Pain may pose significant challenges in the intensive care unit, especially in mechanically ventilated patients. Methadone has recently emerged as an alternative option for eliciting acute analgesia. In this systematic review, we evaluated the use of methadone in mechanically ventilated patients in the intensive care unit.

Source: We searched MEDLINE, EMBASE, Wiley's Cochrane Library, CINAHL, PubMed (non-MEDLINE), Scopus, and LILACS databases from inception to January 24th, 2025. Eligible studies included randomized controlled trials and observational studies that compared the use of methadone to the standard of care or to other analgosedation strategies in mechanically ventilated patients in the intensive …


Adolescent And Caregiver Preparation For Legal Changes At Age 18, Blanca Sanchez-Fournier, Jordyn Babla, Mary Majumder, Beth H Garland, Constance M Wiemann, Albert C Hergenroeder Jan 2025

Adolescent And Caregiver Preparation For Legal Changes At Age 18, Blanca Sanchez-Fournier, Jordyn Babla, Mary Majumder, Beth H Garland, Constance M Wiemann, Albert C Hergenroeder

Center for Medical Ethics and Health Policy Staff Publications

Background: Most adolescents with special healthcare needs (ASHCN) will assume legal responsibility for making decisions about their medical treatment at age 18. Simultaneously, parents or other legal representatives (Caregivers) will lose ASHCN medical record access. This study examined ASHCN and Caregiver knowledge of, satisfaction with, and suggestions for improvement in preparing for these changes.

Methods: Eighty-three dyads (18-year-old ASHCN and Caregivers) completed an assessment to evaluate their knowledge about changes in responsibility for decision making with a focus on consent, satisfaction with the preparation received, and recommendations for improved preparation. Descriptive statistics and mean comparisons were used. Responses to open-ended …


Advancing Medical Applications Of Cancer Nanotechnology: Highlighting Two Decades Of The Nci's Nanotechnology Characterization Laboratory Service To The Research Community, Rachael M Crist, Yechezkel Barenholz, Ahuva Cern, Kate N Clark, Pieter R Cullis, Cheryl Dean, Neil Desai, Mauro Ferrari, Matthieu Germain, Carmen A Giacomantonio, Emma Grabarnik, Piotr Grodzinski, Atara Hod, Barry E Kennedy, Ruvanthi N Kularatne, Glen S Kwon, Emmanuel Loeb, Erin B Noftall, Len Pagliaro, Morteza Rasoulianboroujeni, Alexander Roth, Darren Rowles, Kulbir Singh, Nicole F Steinmetz, Zhanna Yehtina, Yao Zhang, Daniel Zilbersheid, Jeffrey D Clogston, Stephan T Stern, Marina A Dobrovolskaia Jan 2025

Advancing Medical Applications Of Cancer Nanotechnology: Highlighting Two Decades Of The Nci's Nanotechnology Characterization Laboratory Service To The Research Community, Rachael M Crist, Yechezkel Barenholz, Ahuva Cern, Kate N Clark, Pieter R Cullis, Cheryl Dean, Neil Desai, Mauro Ferrari, Matthieu Germain, Carmen A Giacomantonio, Emma Grabarnik, Piotr Grodzinski, Atara Hod, Barry E Kennedy, Ruvanthi N Kularatne, Glen S Kwon, Emmanuel Loeb, Erin B Noftall, Len Pagliaro, Morteza Rasoulianboroujeni, Alexander Roth, Darren Rowles, Kulbir Singh, Nicole F Steinmetz, Zhanna Yehtina, Yao Zhang, Daniel Zilbersheid, Jeffrey D Clogston, Stephan T Stern, Marina A Dobrovolskaia

Center for Medical Ethics and Health Policy Staff Publications

The Nanotechnology Characterization Laboratory (NCL) is a US federally funded resource providing characterization and expertise to the cancer nanomedicine research community. Founded as a formal partnership among the US National Cancer Institute (NCI), the US Food and Drug Administration (FDA), and the US National Institute of Standards and Technology (NIST), the NCL has spent two decades developing a one-of-a-kind service with broad multidisciplinary expertise to meet the needs of a rapidly evolving drug development field. To mark the 20th anniversary of the lab's founding, the NCL hosted a symposium to highlight the achievements of the cancer nanomedicine field, showcase novel, …


Impact Of Personalized Risk Scores On Shared Decision Making In Left Ventricular Assist Device Implantation: Findings From A Qualitative Study, Holland Kaplan, Kristin Kostick-Quenet, Benjamin Lang, Robert J Volk, Jennifer Blumenthal-Barby Jan 2025

Impact Of Personalized Risk Scores On Shared Decision Making In Left Ventricular Assist Device Implantation: Findings From A Qualitative Study, Holland Kaplan, Kristin Kostick-Quenet, Benjamin Lang, Robert J Volk, Jennifer Blumenthal-Barby

Center for Medical Ethics and Health Policy Staff Publications

Objective: To assess stakeholders' perspectives on integrating personalized risk scores (PRS) into left ventricular assist device (LVAD) implantation decisions and how these perspectives might impact shared decision making (SDM).

Methods: We conducted 40 in-depth interviews with physicians, nurse coordinators, patients, and caregivers about integrating PRS into LVAD implantation decisions. A codebook was developed to identify thematic patterns, and quotations were consolidated for analysis. We used Thematic Content Analysis in MAXQDA software to identify themes by abstracting relevant quotes.

Results: Clinicians had varying preferences regarding PRS integration into LVAD decision making, while patients and caregivers preferred real-time discussions about PRS with …


Deep Brain Stimulation For Childhood Treatment-Resistant Obsessive-Compulsive Disorder: Mental Health Clinician Views On Candidacy Factors, Ilona Cenolli, Tiffany A Campbell, Natalie Dorfman, Meghan Hurley, Jared N Smith, Kristin Kostick-Quenet, Eric A Storch, Jennifer Blumenthal-Barby, Gabriel Lázaro-Muñoz Jan 2025

Deep Brain Stimulation For Childhood Treatment-Resistant Obsessive-Compulsive Disorder: Mental Health Clinician Views On Candidacy Factors, Ilona Cenolli, Tiffany A Campbell, Natalie Dorfman, Meghan Hurley, Jared N Smith, Kristin Kostick-Quenet, Eric A Storch, Jennifer Blumenthal-Barby, Gabriel Lázaro-Muñoz

Center for Medical Ethics and Health Policy Staff Publications

Introduction: Deep brain stimulation (DBS) is approved under a humanitarian device exemption to manage treatment-resistant obsessive-compulsive disorder (TR-OCD) in adults. It is possible that DBS may be trialed or used clinically off-label in children and adolescents with TR-OCD in the future. DBS is already used to manage treatment-resistant childhood dystonia. Evidence suggests it is a safe and effective intervention for certain types of dystonia. Important questions remain unanswered about the use of DBS in children and adolescents with TR-OCD, including whether mental health clinicians would refer pediatric patients for DBS, and who would be a good candidate for DBS.

Objectives: …


Talking About Suffering In The Intensive Care Unit, Brent M Kious, Judith B Vick, Peter A Ubel, Olivia Sutton, Jennifer Blumenthal-Barby, Christopher E Cox, Deepshikha Ashana Jan 2025

Talking About Suffering In The Intensive Care Unit, Brent M Kious, Judith B Vick, Peter A Ubel, Olivia Sutton, Jennifer Blumenthal-Barby, Christopher E Cox, Deepshikha Ashana

Center for Medical Ethics and Health Policy Staff Publications

Background: Some have hypothesized that talk about suffering can be used by clinicians to motivate difficult decisions, especially to argue for reducing treatment at the end of life. We examined how talk about suffering is related to decision-making for critically ill patients, by evaluating transcripts of conversations between clinicians and patients' families.

Methods: We conducted a secondary qualitative content analysis of audio-recorded family meetings from a multicenter trial conducted in the adult intensive care units of five hospitals from 2012-2017 to look at how the term "suffering" and its variants were used. A coding guide was developed by consensus-oriented discussion …


Moving Beyond Simplistic Research Design In Health Professions Education: What A One-Group Pretest-Posttest Design Will Not Prove, S Beth Bierer, Gary Beck Dallaghan, Nicole J Borges, Sam Brondfield, Cha Chi Fung, Kathryn N Huggett, Cayla R Teal, Satid Thammasitboon, Colleen Y Colbert Jan 2025

Moving Beyond Simplistic Research Design In Health Professions Education: What A One-Group Pretest-Posttest Design Will Not Prove, S Beth Bierer, Gary Beck Dallaghan, Nicole J Borges, Sam Brondfield, Cha Chi Fung, Kathryn N Huggett, Cayla R Teal, Satid Thammasitboon, Colleen Y Colbert

Center for Medical Ethics and Health Policy Staff Publications

Introduction: Educational research presents unique study design challenges. Novice researchers in health professions education (HPE) frequently misuse the one-group pretest-posttest design, highlighting the need for improved training in research design. This workshop aimed to enhance understanding of research design among novice HPE researchers, specifically addressing the inherent limitations of the one-group pretest-posttest design and offering alternative approaches.

Methods: Experienced HPE researchers developed this workshop to address common misunderstandings of research design. Leaders from the AAMC Medical Education, Scholarship, Research, and Evaluation section facilitated 60-75-minute workshops conducted at the four 2024 regional meetings hosted by the AAMC Group on Educational Affairs …


Different Responses Involving Tfh Cells Delay Parasite-Specific Antibody Production In Trypanosoma Cruzi Acute Experimental Models, Ana Carolina Leão, Maria Jose Villar, Rakesh Adhikari, Cristina Poveda, Leroy Versteeg, Gregório Almeida, Peter J Hotez, Maria Elena Bottazzi, Kathryn M Jones Jan 2025

Different Responses Involving Tfh Cells Delay Parasite-Specific Antibody Production In Trypanosoma Cruzi Acute Experimental Models, Ana Carolina Leão, Maria Jose Villar, Rakesh Adhikari, Cristina Poveda, Leroy Versteeg, Gregório Almeida, Peter J Hotez, Maria Elena Bottazzi, Kathryn M Jones

Center for Medical Ethics and Health Policy Staff Publications

Introduction: Chagas disease (CD), caused by the parasite Trypanosoma cruzi, affects millions globally. Despite treatment options in the acute phase, most infections progress to a chronic indeterminate form or develop severe cardiac/gastrointestinal complications. Understanding the immune response is crucial for the development of vaccines and more efficient drugs for the disease control.

Methods: This work investigates the immune response to T. cruzi H1 K68 strain infection in female BALB/c and C57BL/6 mice to characterize differences in Tfh and B cell responses that may be involved in the poor parasite-specific antibody production during acute infection. For this, mice were euthanized …


Examining Treatment Options In Youth With Major Depressive Disorder: Observations From The Tx-Ydsrn Registry Study, Emine Rabia Ayvaci, Karabi Nandy, Ryan Becker, Laura Stone, Abu Minhajuddin, Holli Slater, Lynnel C Goodman, Sarah M Wakefield, Eric A Storch, Joseph C Blader, Cesar A Soutullo, Graham J Emslie, Madhukar H Trivedi Jan 2025

Examining Treatment Options In Youth With Major Depressive Disorder: Observations From The Tx-Ydsrn Registry Study, Emine Rabia Ayvaci, Karabi Nandy, Ryan Becker, Laura Stone, Abu Minhajuddin, Holli Slater, Lynnel C Goodman, Sarah M Wakefield, Eric A Storch, Joseph C Blader, Cesar A Soutullo, Graham J Emslie, Madhukar H Trivedi

Center for Medical Ethics and Health Policy Staff Publications

Objective: Treatment decisions for depression are a complex process, influenced by factors such as clinical characteristics, socioeconomic factors, and patient/caregiver preferences. This study examines the characteristics of treatment options during the first month of enrollment among depressed youth.

Methods: Data for 646 depressed youth were extracted from the Texas Youth Depression and Suicide Research Network study. Participants' treatments during the first month were categorized as no treatment (NT), psychotherapy only (THER), pharmacotherapy only (MED), or a combination of psychotherapy and pharmacotherapy (COMB). Sociodemographic and clinical features were compared across these treatment types.

Results: 7% were on NT, 5% on THER, …


Reframing Stigma In Tourette Syndrome: An Updated Scoping Review, Kelly Pring, Melina Malli, Brandy W Hardy, Stephen R Rapp, Eric A Storch, Jonathan W Mink, Jaclyn M Martindale Jan 2025

Reframing Stigma In Tourette Syndrome: An Updated Scoping Review, Kelly Pring, Melina Malli, Brandy W Hardy, Stephen R Rapp, Eric A Storch, Jonathan W Mink, Jaclyn M Martindale

Center for Medical Ethics and Health Policy Staff Publications

Persistent tic disorders (PTD) such as Tourette's syndrome (TS) are common childhood-onset neurodevelopmental disorders. Stigmatization of individuals with these disorders remains an ongoing problem. The purpose of this scoping review is to serve as an updated review of the research regarding stigmatization in youth with PTD since the publication of the original systematic review about this topic in 2016. The electronic databases Embase, Web of Science, PubMed, PsycINFO, and CINAHL were searched. Of the 4751 initial articles screened after removing duplications, 47 studies met the inclusion criteria. The studies were examined under the social-ecological stigmatization model, which helps categorize stigmatization …


A Landscape Analysis Of Psychedelic Retreat Organizations Advertising Online, Logan Neitzke-Spruill, Caroline S Beit, Jill Oliver Robinson, Nikita Singh, Srijith Kambala, Rishi Ramesh, Amy L Mcguire Jan 2025

A Landscape Analysis Of Psychedelic Retreat Organizations Advertising Online, Logan Neitzke-Spruill, Caroline S Beit, Jill Oliver Robinson, Nikita Singh, Srijith Kambala, Rishi Ramesh, Amy L Mcguire

Center for Medical Ethics and Health Policy Staff Publications

Research into psychedelics' clinical potential has corresponded to a growth in public interest and adult use. One common pathway to accessing psychedelics is through psychedelic retreats. While individual retreats have been characterized in the anthropological literature, no systematic evaluation of the psychedelic retreat industry exists. Assessing the characteristics of the psychedelic retreat industry is critical to understanding the associated ethical, legal, and social implications and ensuring consumer safety. To this end, we conducted a landscape analysis of online, publicly available information to capture and characterize a broad range of organizations offering psychedelic retreats and marketing to English-speaking consumers. From July …


Patient-Centric Federated Learning: Automating Meaningful Consent To Health Data Sharing With Smart Contracts, Kristin M Kostick-Quenet, Marcelo Corrales Compagnucci, Mateo Aboy, Timo Minssen Jan 2025

Patient-Centric Federated Learning: Automating Meaningful Consent To Health Data Sharing With Smart Contracts, Kristin M Kostick-Quenet, Marcelo Corrales Compagnucci, Mateo Aboy, Timo Minssen

Center for Medical Ethics and Health Policy Staff Publications

Federated Learning (FL) promises to enhance data-driven health research by enabling collaborative machine learning across distributed datasets without direct data exchange. However, current FL implementations primarily reflect the data-sharing interests of institutional controllers rather than those of individual patients whose data are at stake. Existing consent mechanisms-like broad consent under HIPAA or explicit consent under the GDPR-fail to provide patients with control over how their data is used. This article explores the integration of smart contracts (SCs) into FL as a mechanism for automating, enforcing, and documenting consent in data transactions. SCs, encoded in decentralized ledger technologies, can ensure that …


Cyberattacks On Port Infrastructures: A Decade Of Trends, Incidents, And Mitigation Strategies (2011-2024), Minodora Badea, Olga Bucovetchi, Adrian V. Gheorghe, Gabriel Raicu Jan 2025

Cyberattacks On Port Infrastructures: A Decade Of Trends, Incidents, And Mitigation Strategies (2011-2024), Minodora Badea, Olga Bucovetchi, Adrian V. Gheorghe, Gabriel Raicu

Engineering Management & Systems Engineering Faculty Publications

Port infrastructures are critical to global trade, handling over 80% of the world's cargo by volume. However, their increasing reliance on digital technologies has exposed them to a wide range of cyber threats. This paper provides a comprehensive analysis of cyberattacks targeting port infrastructures from 2011 to the present. We examine the types of attacks, geographical distribution, notable incidents, and underlying vulnerabilities. Additionally, we discuss mitigation strategies and future directions for enhancing cybersecurity in the maritime sector. Our findings highlight the urgent need for robust regulatory frameworks, advanced technological solutions, and collaborative efforts to safeguard critical port operations.


“Tw-Ironic": The Ironic Consumption Of Media Examined Through Twilight, Sydney J. Rooney Jan 2025

“Tw-Ironic": The Ironic Consumption Of Media Examined Through Twilight, Sydney J. Rooney

Pell Scholars and Senior Theses

“It’s so bad it’s good” is a phrase often uttered in order to justify watching, reading, or listening to a piece of media with a poor reputation. In the 20 years since the first novel’s debut, the Twilight saga has become renowned for its massive level of popularity and influence. However, it has also faced a great deal of backlash and criticism for a variety of reasons, which affected the nature of the fan base. Through analysis of short-form content, the ironic consumption of Twilight media is observed in contemporary times.


A New Frontier In Political Communications: Analyzing The Electoral Influence Of The 1960 Televised Presidential Debates, Leah Spengler Jan 2025

A New Frontier In Political Communications: Analyzing The Electoral Influence Of The 1960 Televised Presidential Debates, Leah Spengler

Pell Scholars and Senior Theses

Although Kennedy’s success in the 1960 election is often attributed to his performance in the first televised presidential debates, I contend that the party affiliation of voters and proposed policies by Kennedy, specifically those targeting civil rights, held more weight in securing his victory. The Kennedy image had been carefully curated for over a decade prior to the election, and Kennedy’s performance in the first televised debates reinforced the calm and collected impression he wanted to make to the American people. While his debate performance held significance as it was the first to be televised and led to a discrepancy …