Sports Sciences Commons^™

Menstrual Phase Symptoms And Perceived Musculoskeletal Strength And Flexibility Among Ncaa Collegiate Athletes, Ashton N. Vasquez, Kristen Mcalexander

International Journal of Exercise Science: Conference Proceedings

Previous findings suggest that the associations among menstrual hormones, symptoms and human performance are inconsistent and lacking. Earlier research has measured hormonal fluctuations and symptoms from each of the four menstrual phases (menstrual, follicular, ovulation, and luteal), but their physiological effects on perceived musculoskeletal strength and perceived flexibility remain unclear, particularly among college athletes. PURPOSE: To measure the prevalence and associations among self-reported menstrual symptoms, perceived overall strength and perceived flexibility in NCAA female athletes during each of the four menstrual phases. METHODS: In the Fall of 2020, a survey consisting of demographic questions and questions of perceived strength, flexibility, …

Map Kinase Phosphatase-5 Regulates Cardiac Adapation To Endurance Exercise, Jaime A. Perales, Dr. Kisuk Min

International Journal of Exercise Science: Conference Proceedings

Endurance exercise induces a beneficial effect on the cardiovascular system and promotes cardio protection against heart disease. It has been established that the mitogen-activated protein kinases (MAPKs) promote the improvement of cardiac function in response to endurance exercise. However, molecular mechanisms of how MAPK signaling pathways regulate cardiac adaptation to endurance exercise remain unclear. The MAPKs are inactivated by MAP kinase phosphatases (MKPs) through direct dephosphorylation. Recently, growing evidence suggests the importance of MKP-5 signaling mechanisms in physiological and pathological processes. Previously, we have demonstrated that MKP-5-deficient skeletal muscle exhibits improved regenerative myogenesis in response to injury and mice lacking …

Exploring The Differences In Stress Mindset Between Former And Current College Student-Athletes, Creighton Avery, Amber M. Shipherd

International Journal of Exercise Science: Conference Proceedings

Stress is a universal experience, often believed to be negative, that has been linked with negative consequences. However, recent studies have shown that stress can lead to positive outcomes as well, including an increase in health and performance in a variety of domains. Research has also found one’s beliefs about the nature of stress (e.g., stress mindset) play a large role in the extent to which one experiences these beneficial outcomes of stress. Although two athletes may encounter the same stressor, their beliefs on stress impact whether they experience detrimental or enhancing outcomes resulting from the stressor. Given some athletes …

Cross-Sectional And Longitudinal Relationships Between Skinfold Thicknesses Obtained By Ultrasonography And Body Fat Estimates Produced By Dual-Energy X-Ray Absorptiometry, Jacob J. Green, Robert W. Smith, Patrick S. Harty, Matthew T. Stratton, Christian Rodriguez, Sarah White, Abegale D. Williams, Baylor A. Johnson, Jacob Dellinger, Marqui Benavides, Madelin R. Siedler, Grant M. Tinsley

International Journal of Exercise Science: Conference Proceedings

Ultrasonography (US) and dual-energy X-ray absorptiometry (DXA) are frequently used to assess body composition. Although sometimes compared cross-sectionally, their agreement longitudinally requires further exploration. Purpose: The purpose of the present study was to examine the cross-sectional and longitudinal relationships between total and segmental raw skinfold thicknesses obtained by US and total and segmental body composition estimates produced by DXA over the course of an overfeeding study. Methods: Twenty healthy, resistance-trained males (mean ± SD; age: 22.0 ± 2.6 years; height: 179.1 ± 7.0 cm; body mass: 74.8 ± 11.5 kg, body fat: 17.5 ± 4.5%) completed a 6-week intervention that …

Anthropometric Predictors Of Concentric Hip, Knee, And Ankle Work During A 5x5 Conventional Deadlift Routine, Dale S. Keith, Daniel Scherrer, Brandon Nunley, John R. Harry, Grant M. Tinsley

International Journal of Exercise Science: Conference Proceedings

The deadlift is one of the most commonly performed exercises to strengthen the lower body, as well as one of the main lifts in powerlifting and strongman competitions. However, literature exploring the deadlift exercise and its variations remains quite limited compared to other popular exercises like squats and bench press. PURPOSE: The purpose of this exploratory analysis was to determine if there are relationships between anthropometric characteristics (arm length, torso length, thigh length, and shank length) and hip, knee, and ankle joint angular concentric work during a 5 sets of 5 repetitions (5x5) conventional deadlift (CDL) routine. METHODS: …

Offseason Body Composition Changes Detected By Dual-Energy X-Ray Absorptiometry Versus Multifrequency Bioelectrical Impedance Analysis In Collegiate American Football Athletes, Jake R. Boykin, Grant M. Tinsley, Christine M. Harrison, Jessica Prather, Javier Zaragoza, Matthias Tinnin, Shay Smith, Camden Wilson, Lem Taylor

International Journal of Exercise Science: Conference Proceedings

In American football, offseason training is designed to promote increases in muscle strength and size in athletes. Tracking changes in body composition may confer key information about the effectiveness of training programs to football practitioners. PURPOSE: The present study assessed the relationship between body composition changes estimated by dual-energy x-ray absorptiometry (DXA) and bioelectrical impedance analysis (BIA) in football players during the initial period of an offseason training program. METHODS: Body composition in 29 NCAA Division III American football players (mean ± SD; age: 19.7 ± 1.5 y; height: 179.8 ± 6.6 cm; body mass [BM]: 96.1 ± …

Acute Responses In Agonists Of Uegf To Moderate-Intensity And High-Intensity Interval Exercise In Mid-Spectrum Ckd, Kathleen E. Adair, Zacharias Papadakis, Matthew N. Peterson, Cassidy Beeson, James K. Taylor, Burritt W. Hess, D. Crawford Allison, Nick Schwedock, Jackson O. Griggs, Ron Wilson Md, Kathryn Dugan, Kathy Jones, Peter W. Grandjean, Jeff S. Forsse

International Journal of Exercise Science: Conference Proceedings

Urine epidermal growth factor (uEGF) is a novel biomarker utilized in assessing renal health in various renal diseases, specifically chronic kidney disease (CKD). uEGF promotes multiple intracellular pathways, stimulating renal cell growth, survival, and replication. uEGF production is activated by multiple agonists that bind to the uEGF receptor. Aerobic exercise initiates the upregulation of several of these agonists to increase the production of uEGF. Depending on the mode and intensity of aerobic exercise, uEGF agonists may activate differently in CKD populations. PURPOSE: To determine the influence of an acute bout of steady-state exercise (SSE) and high-intensity interval exercise (HIIE) on …

Analyzing The Between-Day Reliability Of Three-Dimensional Body Scanners For Body Composition Assessment, Gabrielle C. Dehaven, Madelin R. Siedler, Matthew T. Stratton, Patrick S. Harty, Christian Rodriguez, Dale Keith, Jacob Green, Jake Boykin, Jacob Dellinger, Sarah White, Abegale D. Williams, Grant M. Tinsley

International Journal of Exercise Science: Conference Proceedings

In the growing world of health and well-being, three-dimensional (3D) scanning is emerging as a popular tool to assess body composition. While body composition cannot be truly “measured” in living humans, it can be approximated. This, however, leads to two types of errors (i.e., technical and biological) in the body composition assessment. PURPOSE: This study was used to determine what percent or range of percentages in body fat one must exceed before concluding a real change has occurred. By conducting assessments on separate days, with only a short period of time between them, true changes in body composition are …

Relationships Between Functional Performance And Quadriceps Muscle Size And Quality In Healthy Older Women, Ahalee C. Farrow, Chinonye C. Agu-Udemba, Ethan A. Mitchell, Ty B. Palmer

International Journal of Exercise Science: Conference Proceedings

Ultrasound assessments of quadriceps cross-sectional area (CSA) and echo intensity (EI) are commonly used to evaluate lower-body muscle size and quality in older adults. It has been hypothesized that muscle CSA and EI of the quadriceps may be important predictors of functional performances such as gait speed and vertical jump power. However, limited data exist regarding how these parameters associate with performance during a timed up-and-go (TUG) task. PURPOSE: The purpose of this study was to examine the relationships between TUG performance and muscle CSA and EI of the quadriceps in older women. METHODS: Twenty healthy older women …

Sex Moderates The Fitness Tests - Performance Index Relationship In Collegiate Basketball: A Case Study, Nicole Kingsley, Samuel Amsbaugh, Zacharias Papadakis, Grant Morgan, Ali Boolani, Andreas Stamatis Dr.

International Journal of Exercise Science: Conference Proceedings

Performance indicators are used widely in sports, including basketball. Those total performance metrics are mathematical models that are used to determine the “best” athlete per game/week/season. Players with higher metrics get recruited more and/or get offered better contracts. During offseason, strength and conditioning coaches (SCCs) perform tests to determine the fitness levels of their players. Although those scores differ by sex, the fitness levels are associated with in-season sport performance and, therefore, performance indices. More insight in the fitness tests - performance index relationship in the collegiate basketball and the differential effects by sex would be valuable for all stakeholders …

Hemodynamics After Glucose Loading In Hispanics With And Without Family History Of Type 2 Diabetes, Gabriel Figueroa, Ryan D. Russell, Yu Lun Tai

International Journal of Exercise Science: Conference Proceedings

Type 2 Diabetes (T2D) increases cardiovascular mortality 4-fold. Although ~9% of Americans are diagnosed with T2D, T2D incidence is substantially higher in Hispanics and those with a have family history of T2D. Traditionally, T2D is diagnosed via oral glucose testing which has been shown to impair microvascular function. However, the effects of glucose loading on hemodynamics and arterial elasticity between healthy Hispanics with and without a family history of T2D are unclear. PURPOSE: To determine the effects of an oral glucose challenge (OGC) and a mixed meal challenge (MMC) on hemodynamics in healthy Hispanic individuals with and without family …

Sex Differences In Absolute And Normalized Rapid Force During Maximal Handgrip Contractions, Alisa Soloveva, Garrett Augsburger, Joshua Carr

International Journal of Exercise Science: Conference Proceedings

Sex differences in strength are well documented. However, the influence of the strength disparity on the absolute and normalized rate of force development (RFD) is not as well described, particularly for the handgrip. PURPOSE: The purpose of this study was to examine differences in absolute and normalized RFD between sexes during maximal handgrip contractions. METHODS: During a single visit, 32 right-hand dominant participants (n = 16 males, n = 16 females) performed maximal, unilateral isometric handgrip contractions with their dominant hands. Maximal force, the RFD from 0-50ms (RFD₅₀), 0-100ms (RFD₁₀₀), and peak RFD (RFD …

Intermittent Hypoxia Increases Erythropoietin Levels In Healthy Individuals, Frank Wojan, Sten Stray-Gundersen, Mercedes J. Nagel, Sophie Lalande

International Journal of Exercise Science: Conference Proceedings

Few minutes of hypoxic exposure stabilizes hypoxia-inducible factor-1α, resulting in erythropoietin (EPO) gene transcription and production. PURPOSE: The objective of this study was to identify the shortest intermittent hypoxia protocol necessary to increase serum EPO levels in healthy individuals. We hypothesized that two separate intermittent hypoxia protocols would significantly increase EPO levels in healthy individuals. METHODS: A total of seven individuals (4 women and 3 men, age: 28±7 years, height: 177±9 cm, weight: 79.7±18.4 kg) participated in the study. In Experiment 1, the spontaneous EPO changes under normoxia (NORM) and the EPO response to five 4-minute cycles of …

A Case Study: Femoroacetabular Impingement In Collegiate Baseball, Candace Parker, Morgan Spencer-Roth

International Journal of Exercise Science: Conference Proceedings

CASE HISTORY: The patient is a 19-year-old collegiate baseball infielder who presented with an ongoing pain in his left hip that had originally presented when the patient was in high school. After becoming a member of a collegiate baseball team, his hip pain persisted, followed shortly by a new pain in his right hip. The patient had been dealing with and conservatively treating the left hip pain for a year, and with the presentation of right hip pain during his first collegiate semester a decision was made to visit the team physician. PHYSICAL EXAM: Examination of the patient’s …

Partial Rupture Of The Distal Biceps Tendon In A Collegiate Football Player, Derran J. Strydom, Melissa D. Long

International Journal of Exercise Science: Conference Proceedings

CASE HISTORY: The patient is a 20-year-old collegiate football player who presented to the athletic training staff with pain in his left arm near his elbow. He states that he was attempting to make a tackle and that his arm was pushed into hyperextension by another player. He reported discomfort, pain, and numbness in his arm. He attempted to continue to play after completing arm flexion and extension in between plays. His pain levels increased as his range of motion activity continued. The patient could no longer continue during practice and was taken to the medical tent for further …

The Relationship Between Squat Jump Performance And Sprint Profile In Collegiate Track And Field Athletes, Martin S. Dietze-Hermosa, Sergio Rodriguez, Samuel Montalvo, Matthew P. Gonzalez, Nicholas R. Cubillos, Emily Martinez, Joshua Del Rio, Sandor Dorgo

International Journal of Exercise Science: Conference Proceedings

The squat jump (SJ) necessitates the inter-play of various biomechanical components for better jump performance. Good sprint performance requires the inter-play of many of the same biomechanical components. Researchers have previously examined how the speed, force, velocity, and power interact during sprinting, but have yet to examine how these measures are associated with SJ performance measures. PURPOSE: Examine the relationship between squat jump performance measures and the sprint profile measurements of collegiate track and field athletes. METHODS: Twenty-five athletes (18 males and 7 females) completed two squat jump trials with a linear encoder attached to a 45 lbs. …

Differences In Acute:Chronic Workload Ratio Preceding Injury Occurrence In United Soccer League Players, Steve P. Fell, Brennen Hodge, Andreas Stamatis, Zacharias Papadakis

International Journal of Exercise Science: Conference Proceedings

Professional soccer players are prone to injuries. Training loads (TL), including games, are associated with injury occurrence. Acute:Chronic workload ratio (ACWR), an index of TL, is considered an accurate injury rate metric. In respect to the relationship between injury occurrence and ACWR load obtained using global positioning systems (GPS), little evidence exists in United Soccer League (USL) teams. It is possible high ACWR during the season to lead to injuries. PURPOSE: To investigate the interaction effect of players’ injury status with ACWR of professional soccer players of a USL team. METHODS: In 2019-20, in-season data were gathered from 20 …

Handgrip Strength And Vo2max Trends In Police Cadets: A Case Study, Kendrick Morris, Filip Kukic, Nenad Koropanovski, Andreas Stamatis Dr., Zacharias Papadakis

International Journal of Exercise Science: Conference Proceedings

Among other components of physical fitness, performance on tactical tasks depends on cardiorespiratory endurance (CE) and muscular strength (MS). Police academies’ curriculum aim to increase cadets’ CE and MS, with males outscoring females in both tests. Curricula should assist cadets to adopt and adhere to a physically-active lifestyle while in the academy and upon graduation, for both health-related benefits and success in their tactical tasks. PURPOSE: To explore both CE-MS and sex trends between a four-year curriculum. METHODS: Retrospective data of 98 males and 79 females analyzed. Besides the senior year, cadets receive physical education classes. This serves as the …

United States Special Operations Command South Training Program’S Effectiveness: A Case Study, Gene Hansen, Steve Fell, Jarrod Lubbers, Mindy Langlois, Jacob Talcott, Andreas Stamatis, Zacharias Papadakis

International Journal of Exercise Science: Conference Proceedings

United States Special Operations Command South (SOCSOUTH) plans and coordinates Special Operations to find and fix threats and enable the Interagency, Intelligence Community, and Partner Nations to counter threats to US interests, maintain regional stability and compete in a complex environment. Physical readiness, performance optimization, and injury prevention are critical to the individual operator. SOCSOUTH has allocated significant financial resources associated with operational training and human performance programs in order to improve and maintain operators’ tactical and physical readiness. Whether these efforts are pointed to the right direction are under evaluation. PURPOSE: To evaluate the effectiveness of a 3 months’ …

Fear Of Covid-19 And Adherence To Lockdown Deteriorated Police Cadets’ Handgrip Strength Relative To Bmi, Courtnie R. Moodie, Filip Kukic, Nenad Koropanovski, Ana Vesković, Nicola Petrović, Andreas Stamatis Dr., Zacharias Papadakis

International Journal of Exercise Science: Conference Proceedings

Due to COVID-19 pandemic, police academies enforced lockdowns to protect cadets’ well-being. Fear of health issues (e.g., perceived severity) influences ones’ adherence (e.g., readiness to act) to changes in exercise behavior. According to WHO, modifications in exercise behavior during the pandemic influence health status. A well-established clinical health marker is the handgrip strength relative to body mass index (HS_R). The relationship between fear and physical well-being during COVID-19 is still under investigation. The mediating effect of adherence to COVID-19 restrictions on the fear-health status relationship in police cadetsis unknown. PURPOSE: To explore a) the fear-HS_R relationship and …

Covid-19 Adherence To Physical Activity Guidelines Moderates The Mental Health/Toughness Relationship On Black/Hispanic Females, Melissa Dorvily, Michelle Etchebaster, Andreas Stamatis Dr., Jeff S. Forsse, Tal Amasay, Zacharias Papadakis

International Journal of Exercise Science: Conference Proceedings

Physical activity (PA) improves mental health (MH). Mental toughness (MT) positively correlates to MH. Only 45% of Hispanics and Blacks over 18 years and less than 40% of US females meet the ACSM PA guidelines. PA has been decreasing during the COVID-19. PURPOSE: Investigate during the pandemic the effect of PA adherence on the MT-MH relationship on previously physically active, Black and Hispanic females. METHODS: Fifteen females (age 21.3±3.6 yr), six Hispanic and nine Black, who met the ACSM guidelines before the pandemic, completed the Mental Health Continuum and Mental Toughness Index inventories, while reporting their PA habits during …

Is The Acsm And Friend Metabolic Equations Valid For Assessing Cardiorespiratory Fitness Among 18-34 Aged Men? : Preliminary Results, Marc-Olivier Dugas, Laurie Simard, Tommy Chevrette, Martin Lavalliere

Topics in Exercise Science and Kinesiology

Topics in Exercise Science and Kinesiology Volume 2: Issue 1, Article 2, 2021. Metabolic equations, such as ACSM and FRIEND, are used worldwide to indirectly measure the VO₂max in adults, but lack of accuracy seems to occur. 30 men of 18-34 years old performed a maximal incremental test on a treadmill during which direct VO₂max measurements was taken and then have been compared to ACSM and FRIEND metabolic equations. Point of application #1: Better evaluation and exercise prescription among athletic populations. Point of application #2: Act in prevention among sedentary and symptomatic populations. Point of application …

Managing Vibration Training Safety By Using Knee Flexion Angle And Rating Perceived Exertion, Long-Ren Chuang, Wen-Wen Yang, Po-Ling Chang, Vincent Chiun-Fan Chen, Chiang Liu, Tzyy-Yuang Shiang

Engineering Science Faculty Publications

Whole-body vibration (WBV) is commonly applied in exercise and rehabilitation and its safety issues have been a major concern. Vibration measured using accelerometers can be used to further analyze the vibration transmissibility. Optimal bending angles and rating of perceived exertion (RPE) evaluations have not been sufficiently explored to mitigate the adverse effect. Therefore, the aims of this study were to investigate the effect of various knee flexion angles on the transmissibility to the head and knee, the RPE during WBV exposure, and the link between the transmissibility to the head and the RPE. Sixteen participants randomly performed static squats with …

Survey Of Prevention And Intervention Strategies Reducing Return To Play Post-Concussion In Division 1 Football, Joseph F. Clark, Enna Selmanovic, Kip Drewry, Jon Vincent, Aaron Himmler, Bob Mangine, Kim Hasselfeld, Jane Khoury, David Polanski, Jon Divine

Journal for Sports Neuroscience

Abstract.

Introduction

Sports related concussion, also considered mTBI, has remained in the public eye due to heightened fear concerning playing football and other collision based sports. Concussion prevention, as well as rehabilitating the brain after a concussion, is a high priority for many sports medical practitioners as well as for athletes. For these reasons, researchers associated with the American Athletic Conference (AAC) have surveyed concussion incidence in football. One of the AAC teams engaged in regular neurovisual training (NVT) and concluded this training program is associated with faster return to play post-injury in this observational cohort study.

Methods

The …

An Objective Method To Assess And Recommend Exertion And Exercise Targets For Return To Play Post Concussion, Joseph F. Clark Phd Atc, Robert E. Mangine Pt Med Atc, Kimberly A. Hasselfeld Ms, Violet T. Schramm, Angelo J. Colosimo Md, Aaron Kuehn-Himmler At Ms, Gerald M. Holloway Ms Atc, Faniel Fosselman Do Mba, Jon Vincent, Nicole Giordano, Jon G. Divine Md Ms

Journal for Sports Neuroscience

Introduction.

Concussions are of significant concern for athletic trainers, and there is a critical need to objectively and safely allow an athlete to return to play. In sports the objective is return as safely and soon as possible. Exertion is a consideration regarding progressing an athlete back to play. The ability to exert in cardiovascular and strength and conditioning contexts are two critical steps in most return to play protocols. Being able to make objective recommendations is urgently needed, as trial and error leads to unnecessary risk of eliciting symptoms and/or causing setbacks.

Objective.

The object of this paper is …

Applications Of The Critical Power Model To Dynamic Constant External Resistance Exercise: A Brief Review Of The Critical Load Test, Haley C. Bergstrom, Taylor K. Dinyer, Pasquale J. Succi, Caleb C. Voskuil, Terry J. Housh

Kinesiology and Health Promotion Faculty Publications

The study and application of the critical power (CP) concept has spanned many decades. The CP test provides estimates of two distinct parameters, CP and W′, that describe aerobic and anaerobic metabolic capacities, respectively. Various mathematical models have been used to estimate the CP and W′ parameters across exercise modalities. Recently, the CP model has been applied to dynamic constant external resistance (DCER) exercises. The same hyperbolic relationship that has been established across various continuous, whole-body, dynamic movements has also been demonstrated for upper-, lower-, and whole-body DCER exercises. The asymptote of the load versus repetition relationship is defined as …

Predicting Young Adults’ Intentions And Involvement In Alcohol-Influenced Aquatic Activity, Hannah L M Calverley, Lauren A. Petrass Ph.D., Jennifer D. Blitvich

International Journal of Aquatic Research and Education

Globally, alcohol consumption is a public health issue and a risk factor for drownings among young adults. While studies have identified a prominence of alcohol in youth drownings, little is known about the factors that influence young adults’ involvement in alcohol-influenced aquatic activity. The current study aimed to identify the predictors of young adults’ intention to participate, and past participation, in alcohol-influenced aquatic activity. A reliable and valid survey, informed by the Theory of Planned Behavior, was distributed to young adults (aged 18-24 years) educated in the UK and Australia. Cumulative odds ordinal logistic regressions with proportional odds were …

Important Updates To Submission Types In Topics In Exercise Science And Kinesiology, James W. Navalta, Donald L. Hoover, Robert Salatto, Whitley J. Stone, Scott Lyons

Topics in Exercise Science and Kinesiology

Topics in Exercise Science and Kinesiology Volume 2: Issue 1, Article 1, 2021. While Topics in Exercise Science and Kinesiology (TESK) was originally designed to fill a void in publishing applied information for practitioners in physical activity and sport, the TESK editors have determined a need to update the submission categories. The categories of Process of Science and Implementation Strategies have been retained, and three new types of submissions now will be accepted: Expedited Articles, Review Articles, and Case Studies. Process of Science submissions should seek to answer the question, “What was learned from the experience of performing the investigation?”, …

Changes In Plasma Hydroxyproline And Plasma Cell-Free Dna Concentrations After Higher- Versus Lower-Intensity Eccentric Cycling, Georgios Mavropalias, Leslie Calapre, Michael Morici, Tomoko Koeda, Wayne C. K. Poon, Oliver R. Barley, Elin Gray, Anthony J. Blazevich, Kazunori Nosaka

Research outputs 2014 to 2021

Purpose: We examined changes in plasma creatine kinase (CK) activity, hydroxyproline and cell-free DNA (cfDNA) concentrations in relation to changes in maximum voluntary isometric contraction (MVIC) torque and delayed-onset muscle soreness (DOMS) following a session of volume-matched higher- (HI) versus lower-intensity (LI) eccentric cycling exercise.

Methods: Healthy young men performed either 5 × 1-min HI at 20% of peak power output (n = 11) or 5 × 4-min LI eccentric cycling at 5% of peak power output (n = 9). Changes in knee extensor MVIC torque, DOMS, plasma CK activity, and hydroxyproline and cfDNA concentrations before, immediately after, and 24–72 …

Resting Cerebral Oxygen Metabolism Exhibits Archetypal Network Features, Nicholas A. Hubbard, Monroe P. Turner, Kevin R. Sitek, Kathryn L. West, Jakub R. Kaczmarzyk, Lyndahl Himes, Binu P. Thomas, Hanzhang Lu, Bart Rypma

Center for Brain, Biology, and Behavior: Faculty Publications

Standard magnetic resonance imaging approaches offer high-resolution but indirect measures of neural activity, limiting understanding of the physiological processes associated with imaging findings. Here, we used calibrated functional magnetic resonance imaging during the resting state to recover low-frequency fluctuations of the cerebral metabolic rate of oxygen (CMRO2). We tested whether functional connections derived from these fluctuations exhibited organization properties similar to those established by previous standard functional and anatomical connectivity studies. Seventeen participants underwent 20 min of resting imaging during dual-echo, pseudocontinuous arterial spin labeling, and blood-oxygen-level dependent (BOLD) signal acquisition. Participants also underwent a 10 min normocapnic and hypercapnic …