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Articles 31 - 60 of 80

Full-Text Articles in Oral Medicine

Self-Medication Behavior Of Dental Students With Oral Ulceration Lesions: A Cross-Sectional Study In Yogyakarta, Indonesia, Fita Fathaya Iriana, Hendri Susanto, Rosa Amalia Aug 2025

Self-Medication Behavior Of Dental Students With Oral Ulceration Lesions: A Cross-Sectional Study In Yogyakarta, Indonesia, Fita Fathaya Iriana, Hendri Susanto, Rosa Amalia

Journal of Dentistry Indonesia

Objective: Self-medication refers to medication behavior for self-diagnosed symptoms. Oral ulcers are self-medicated lesions in the oral cavity. Dental students have different knowledge about oral cavity lesions and may self-medicate using drugs. This study aimed to determine the self-medication behavior of dental students for oral ulcers. Methods: This cross-sectional study was conducted on dental students in the Faculty of Dentistry from different batch years. Purposive sampling was used to select students with oral ulcer lesions in the last six months. A validated and reliable questionnaire was used to assess self-medication behavior. Data collection using the online form. Student behavior …


Perception Of Conventional Cigarettes And Vaping Among Smokers And Nonsmokers: A Cross-Sectional Study, Indrayadi Gunardi, Rahmi Amtha, Firstine Kelsi Hartanto, Niko Falatehan, Alyah Heriandi, Angelita Victoria Kurniawan, Najla Nadiah, Wiwiek Poedjiastoeti, Andrijanto Andrijanto, Elizabeth Fitriana Sari Aug 2025

Perception Of Conventional Cigarettes And Vaping Among Smokers And Nonsmokers: A Cross-Sectional Study, Indrayadi Gunardi, Rahmi Amtha, Firstine Kelsi Hartanto, Niko Falatehan, Alyah Heriandi, Angelita Victoria Kurniawan, Najla Nadiah, Wiwiek Poedjiastoeti, Andrijanto Andrijanto, Elizabeth Fitriana Sari

Journal of Dentistry Indonesia

Objectives: The growing popularity of vaping has introduced additional challenges, as potential health risks are still under investigation. Exploring differences in smoking perceptions between smokers and non-smokers could provide valuable insights into smoking behavior and inform effective intervention strategies. This study aimed to evaluate and compare the perceptions of smoking, specifically vaping and conventional cigarette use, among young adult smokers and non-smokers. Methods: An analytical cross-sectional design was employed, with 542 university students included through random sampling, using a questionnaire consisting of 8 items. Data were analyzed using the Kruskal-Wallis test and Rasch model analysis. Results: Of the subjects, 259 …


Temporomandibular Joint Osteoarthritis And Systemic Inflammation: A Cadaveric Study For Dental Insights, Nathan Kent Bs, David Patterson Bs, Alyssa Luu Bs, Samantha Pipkin Bs, Jason Ciccotelli Dpt, Phd, Jeremy James Dmd, Ms, Jessica Immonen Phd, Ms Aug 2025

Temporomandibular Joint Osteoarthritis And Systemic Inflammation: A Cadaveric Study For Dental Insights, Nathan Kent Bs, David Patterson Bs, Alyssa Luu Bs, Samantha Pipkin Bs, Jason Ciccotelli Dpt, Phd, Jeremy James Dmd, Ms, Jessica Immonen Phd, Ms

The Journal of Integrative Physiology

The objective of this study was to determine if gross signs of cadaveric osteoarthritis (OA) have

a tendency to present systemically and if this presentation includes pathology found at the

temporomandibular joint (TMJ). Signs of OA were then correlated to gross alterations of the aorta and common carotid arteries seen with atherosclerotic cardiovascular disease. Ipsilateral synovial joints including the TMJ, knee joint, radiocarpal joint and trapeziometacarpal (TMC) joint were all assessed for signs of OA in 4 cadaveric donors (3 males; 72, 82 and 92 years-old / 1 female; 89 years-old) using a validated scale of disease severity. A Grade …


Lsu School Of Dentistry Launches New Residency In Orofacial Pain Jul 2025

Lsu School Of Dentistry Launches New Residency In Orofacial Pain

New Orleans Dental Association News

Louisiana State University School of Dentistry announces a new two-year Advanced Education Program in Orofacial Pain, launching July 2025. The program provides interdisciplinary training, preparing specialists to manage complex oral and facial pain conditions through clinical care and academic instruction.


Impact Of The Adjunctive Use Of Omega-3 In Periodontitispatients With Diabetes On Local And Systemic Chemerin Levels:A Randomized Clinical Trial, Dalia Ghalwash, Ahmed M. Ammar, Ayman El-Gawish, Ahmed Hamdy Jul 2025

Impact Of The Adjunctive Use Of Omega-3 In Periodontitispatients With Diabetes On Local And Systemic Chemerin Levels:A Randomized Clinical Trial, Dalia Ghalwash, Ahmed M. Ammar, Ayman El-Gawish, Ahmed Hamdy

Dentistry

Aims: The present study aspired to evaluate the impact of the adjunctive use of omega-3 with nonsurgical periodontal therapy onclinical parameters as well as local and systemic chemerin levels as a marker of cardiovascular disease risk in periodontitis patientswith diabetes.Methods: This randomized clinical trial was performed on thirty periodontitis patients with type II diabetes divided into two equalgroups, both treated by nonsurgical periodontal treatment with the adjunctive use of daily 1000 mg Omega-3FAs in group I onlyfor 6 months. Patients were reexamined after 2 weeks (baseline), 3, and 6 months for recording the clinical parameters as follows:plaque index (PI), gingival …


Perception, Usage, And Concerns Of Artificial Intelligence Applications Among Postgraduate Dental Students Cross-Sectional Study, Dalia Ghalwash, Asmaa Abou-Bakr, Susan Sarhan, Amira Badra, Hadeel Almalahy Jun 2025

Perception, Usage, And Concerns Of Artificial Intelligence Applications Among Postgraduate Dental Students Cross-Sectional Study, Dalia Ghalwash, Asmaa Abou-Bakr, Susan Sarhan, Amira Badra, Hadeel Almalahy

Dentistry

Background

Future dental applications of artificial intelligence (AI) are anticipated to be widely adopted across all dental specialities. However, there are some concerns among many users about the accuracy of the given information. Therefore, this study aimed to investigate postgraduate’ dental students’ perception, usage, and concerns towards AI systems’ applications.

Materials and methods

An online self-administered survey, consisting of 19 closed-ended questions in the English language, and a 3-point Likert-type scale was used to obtain a simple and straightforward response from participants in a “forced-choice” response format that was distributed to postgraduate dental students in the faculty of dentistry of …


Oral Cancer Awareness Among Dentists: What Is Missing? A Cross-Sectional Study, Dalia Ghalwash, Fatheya Zahran Jun 2025

Oral Cancer Awareness Among Dentists: What Is Missing? A Cross-Sectional Study, Dalia Ghalwash, Fatheya Zahran

Dentistry

Introduction

Oral cancer (OC) is one of the major global health problems with a high incidence rate in developing countries. Early detection can improve the prognosis and survival rate of the disease.

Aim

The current study evaluates dentists’ general awareness, knowledge, attitude, and practice regarding oral cancer.

Methods

In the current cross-sectional study, a self-reported questionnaire was distributed to a sample of dentists in Egypt. A total of 700 dentists participated. The questionnaire included 27 questions on oral cancer knowledge, opinions, attitudes, and practices.

Results

The highest awareness of risk factors concentrated around tobacco and alcohol consumption, and the most …


Teaming Up For Better Health: An Interprofessional Collaborative Approach To Older Adult Oral Care, Deborah Dowd, Jodie Lopez, Jennifer Goodman May 2025

Teaming Up For Better Health: An Interprofessional Collaborative Approach To Older Adult Oral Care, Deborah Dowd, Jodie Lopez, Jennifer Goodman

Utah Conference on Community Engagement

Oral health is a critical component of overall health, significantly influencing systemic diseases and the quality of life in older adults. Conditions such as xerostomia, swallowing difficulties, and poor oral self-care are associated with aspiration pneumonia. Integrating oral health into healthcare in long-term care facilities (LTCFs) is essential for preventing various conditions and improving quality of life. Effective oral hygiene is crucial in avoiding non-ventilator hospital-associated pneumonia by reducing oral biofilm and lowering the risk of pneumonia. Nurses' knowledge and care in oral health across healthcare settings are vital for positive health outcomes. Revising nursing curricula to incorporate oral health …


Improving Oral Hygiene Practices In A Long-Term Care Setting For Individuals With Advanced Dementia: A Quality Improvement Initiative, Rachel L. Mcinerney May 2025

Improving Oral Hygiene Practices In A Long-Term Care Setting For Individuals With Advanced Dementia: A Quality Improvement Initiative, Rachel L. Mcinerney

Capstone Experience: Master of Public Health

This quality improvement project utilized the Plan-Do-Study-Act framework to enhance oral hygiene practices in a long-term care setting for individuals with advanced dementia. Advanced dementia often leads to significant oral health challenges due to the individuals’ inability to communicate needs or independently manage oral care. Poor oral hygiene results in pain, systemic infections, and reduced quality of life. The project aimed to identify and address barriers to effective oral care delivery by focusing on organizational factors such as leadership, training, and caregiver support. This capstone paper provides insights into the quality improvement initiative’s aims, background, and methodology, while emphasizing its …


Efficacy Of Manuka Honey Oral Rinsein Treatment Of Xerostomia Among Elderlypatients: A Randomized Controlled Trial, Dalia Ghalwash, Asmaa Abou-Bakr, Ayman Elgawish May 2025

Efficacy Of Manuka Honey Oral Rinsein Treatment Of Xerostomia Among Elderlypatients: A Randomized Controlled Trial, Dalia Ghalwash, Asmaa Abou-Bakr, Ayman Elgawish

Dentistry

Background Xerostomia is a common complaint among elderly patients. Due to the anti-inflammatory effect, Manuka honey could be a promising alternative remedy for many medical conditions, including xerostomia. The present study aimed to evaluate the effectiveness of Manuka honey oral rinse as a novel management for xerostomiain elderly patients. Methods This study was designed as a randomized, single-blinded clinical trial. 42 elderly patients who were allevaluated for the presence of xerostomia and hyposalivation were randomly allocated into 3 equal groups. The interventions were used 3 times per day for 1 month as follows: Manuka honey oral rinse in group I, …


Oromandibular Dystonia: A Dental Perspective On Movement Disorders, Hanyu You, Kristi Soileau Dds, Med, Mshce, Facd, Ficd Apr 2025

Oromandibular Dystonia: A Dental Perspective On Movement Disorders, Hanyu You, Kristi Soileau Dds, Med, Mshce, Facd, Ficd

New Orleans Dental Association News

Oromandibular Dystonia (OMD) is a rare movement disorder that causes involuntary muscle contractions in the oromandibular region, affecting jaw function, oral hygiene, and dental health. It can lead to tooth wear, TMD, swallowing difficulties, and significant challenges for musicians, requiring a multidisciplinary approach to management.


Evaluation Of Thymoquinone Cancer Chemo-Preventive Effect On Oral Leukoplakia: A Randomized Clinical Trial, Dalia Ghalwash, Fatheya Zahran Mar 2025

Evaluation Of Thymoquinone Cancer Chemo-Preventive Effect On Oral Leukoplakia: A Randomized Clinical Trial, Dalia Ghalwash, Fatheya Zahran

Dentistry

Aim: This randomized clinical trial aimed to investigate the chemo-preventive role of thymoquinone in Nigella sativa extract in managing oral leukoplakia clinically, histologically, and at the molecular level. Methods: A total of 48 patients with oral leukoplakia were randomly allocated to three groups; Group A received local muco-adhesive tablets with Nigella sativa extract in 10 mg/kg dose, for three months, Group B same intervention but with Nigella sativa extract in 5 mg/kg dose, and lastly Group C was the placebo group. The outcomes assessed were clinical improvement, histologic improvement (degree of dysplasia), and molecular biomarkers Ki-67 and caspase-3 by immunohistochemistry. …


Oral Cancer And The Impact Of Glossectomy: Challenges And Pathways To Recovery, Merna Roman, Kamran H. Awan Feb 2025

Oral Cancer And The Impact Of Glossectomy: Challenges And Pathways To Recovery, Merna Roman, Kamran H. Awan

Annual Research Symposium

No abstract provided.


From Tricare To Medicaid: Dental Insurance Disparities Among U.S. Veterans And Active Duty Service Members, Madeline K. Mcnutt Ms Jan 2025

From Tricare To Medicaid: Dental Insurance Disparities Among U.S. Veterans And Active Duty Service Members, Madeline K. Mcnutt Ms

Honors Undergraduate Theses

Oral health plays a critical role in systemic well-being, yet dental care access in the United States remains deeply unequal, particularly among low-income and historically marginalized populations. Among those significantly affected are military veterans, who frequently experience barriers to oral healthcare due to eligibility restrictions within the Department of Veterans Affairs (VA) system. This study offers a comparative analysis of dental insurance satisfaction between recipients of Medicaid and the TRICARE Active Duty Dental Program (ADDP), two federally funded programs that reflect the divide between civilian and military healthcare access. While TRICARE ADDP provides comprehensive and uniform coverage for Active Duty …


The Impact Of Smoking Cessation On Clinical Outcomes Of Stage I/Stage Ii, Grade A/Grade B Periodontitis Patients In Periodontal Maintenance Phase: A 2-Year Longitudinal Study, Santosh R Patil, Shikhar Daniel, Aysha Jebin A Jan 2025

The Impact Of Smoking Cessation On Clinical Outcomes Of Stage I/Stage Ii, Grade A/Grade B Periodontitis Patients In Periodontal Maintenance Phase: A 2-Year Longitudinal Study, Santosh R Patil, Shikhar Daniel, Aysha Jebin A

International Arab Journal of Dentistry

Objectives: The objective of this study is to investigate the influence of smoking cessation interventions on periodontal outcomes in individuals who have successfully abstained from smoking for a minimum of six months following non-surgical periodontal therapy.

Methods: A total of 122 participants, based on inclusion & exclusion criteria, were divided into a smoking cessation group (n=61) and a control group (n=61). Demographic characteristics, smoking history, and baseline oral health parameters were assessed in these patients. Over a 2-year follow-up period, changes in probing depth and alveolar bone loss were measured, statistically analysis were performed using SPSS software.

Results …


Oral Lesion As The Initial Presentation In The Diagnosis Of Histiocytosis X: A Case Report With 16-Month Follow-Up, Wassim Al Manhal, Georgio Saad, Charbel Anka, Valerie Aftimos, Michael Daccache, Sophie Abi Raad, Georges Boujaoude Jan 2025

Oral Lesion As The Initial Presentation In The Diagnosis Of Histiocytosis X: A Case Report With 16-Month Follow-Up, Wassim Al Manhal, Georgio Saad, Charbel Anka, Valerie Aftimos, Michael Daccache, Sophie Abi Raad, Georges Boujaoude

International Arab Journal of Dentistry

Introduction: Langerhans Cell Histiocytosis (LCH) is a rare neoplastic disease that comes from the abnormal proliferation of Langerhans cells (LCs). It presents with a broad clinical spectrum, varying from involvement of a single organ system to multisystem disease, and frequently affects children, although cases in adults have been reported. Oral manifestations of LCH are non-specific and may mimic common periodontal conditions, posing a diagnostic challenge for dental practitioners.

Case Presentation: A 63-year-old female patient presented with complaints of periodontal problems. She was initially diagnosed with periodontitis, but symptoms persisted despite treatment, prompting a referral for further evaluation. Histopathological …


Prevalence And Impact Of Xerostomia On Quality Of Life: A Clinical-Based Cross-Sectional Study In Egypt, Dalia Ghalwash, Ayman Elgawish, Asmaa Abou-Bakr Jan 2025

Prevalence And Impact Of Xerostomia On Quality Of Life: A Clinical-Based Cross-Sectional Study In Egypt, Dalia Ghalwash, Ayman Elgawish, Asmaa Abou-Bakr

Dentistry

Background The current investigation aimed to assess the prevalence of xerostomia, its relation to risk factors, and its impact on the quality of life among a sample of the Egyptian population.

Methods This cross‑sectional study collected data on the occurrence of xerostomia and risk factors from 1220subjects in several Egyptian governorates, including sex, age, smoking, systemic illness, and medications. Subjective and objective dry mouth scores, taste disturbances, burning sensations, and their impact on quality of life were assessed.

Results Xerostomia was estimated to involve 49.6% of the studied population. It was found to increase with ageand was substantially higher amongst …


Epidemiology Of Recurrent Herpes Labialis Among Dentistry Students: A Cross-Sectional Survey In Egypt, Sara Abdelwahed, Dalia Ghalwash, Al Hassan Diab Jan 2025

Epidemiology Of Recurrent Herpes Labialis Among Dentistry Students: A Cross-Sectional Survey In Egypt, Sara Abdelwahed, Dalia Ghalwash, Al Hassan Diab

Dentistry

Aim: Recurrent herpes labialis (RHL) is a common viral infection with significant psychosocial and clinical implications. Dental students are particularly vulnerable due to stress and frequent patient contact, yet data on their epidemiology in Egyptian cohorts are scarce. The study aimed to determine the prevalence, recurrence patterns, and associated risk factors of RHL among dentistry students in Egypt. Materials and Methods: A cross-sectional survey was conducted among 559 dentistry students at the British University in Egypt. A structured, self-administered questionnaire captured sociodemographic data, history of RHL episodes, frequency, severity, and triggering factors. Data were analyzed using descriptive statistics and Chi-square …


Synergistic Potential Of Ivermectin And Doxorubicin In Oral Squamous Cell Carcinoma: An In Vitro Investigation, Dalia Ghalwash, Shereen Nader, Rana Tantawy Jan 2025

Synergistic Potential Of Ivermectin And Doxorubicin In Oral Squamous Cell Carcinoma: An In Vitro Investigation, Dalia Ghalwash, Shereen Nader, Rana Tantawy

Dentistry

Background Doxorubicin (DOX) is widely used in cancer therapy, but its role in oral squamous cell carcinoma (OSCC)is limited by resistance and dose-related toxicities. Ivermectin (IVM), an antiparasitic agent with emerging anticancer properties, may enhance DOX efficacy. This study evaluated the effects of IVM alone and in combination with DOX on OSCC cell lines.

Methods In vitro assays, including MTT viability, apoptosis (Annexin V/PI), cell cycle analysis, RT-qPCR of apoptotic, proliferative, and inflammatory markers, and oxidative stress assays, were performed on HN9 and HEp-2 OSCC cell lines, with OEC as control.

Results IVM reduced cancer cell viability in a dose-dependent …


Reducing The Incidence Of Nosocomial Aspiration Pneumonia In The Adult Oncology Population Through Improved Compliance With Oral Hygiene Protocols, Kenneth R. Brown Dec 2024

Reducing The Incidence Of Nosocomial Aspiration Pneumonia In The Adult Oncology Population Through Improved Compliance With Oral Hygiene Protocols, Kenneth R. Brown

Master's Projects and Capstones

Objective

Oncology patients receiving chemotherapy are at risk of complications such as mucosal barrier injuries (MBI) and aspiration pneumonia, and aspiration pneumonia rates are higher than desired. Improved oral hygiene protocols and compliance in this population reduces the incidence of these complications.

Context and Background

The microsystem assessed includes six oncology units at Hospital A, a large California academic hospital. Aspiration pneumonia, commonly associated with MBI, is a life-threatening challenge that increases costs and complications in oncological treatment settings. An aspiration pneumonia task force focused on six oncology acute care units is committed to reducing the incidence of hospital acquired …


Epidemiology Of Sjogren’S Syndrome In A Sample Of The Egyptian Population: A Cross-Sectional Study, Dalia Ghalwash, Ahmed M. Ammar, Ahmed Hamdy, Ayman Elgawish, Rim Mazen Oct 2024

Epidemiology Of Sjogren’S Syndrome In A Sample Of The Egyptian Population: A Cross-Sectional Study, Dalia Ghalwash, Ahmed M. Ammar, Ahmed Hamdy, Ayman Elgawish, Rim Mazen

Dentistry

Objective: To investigate the prevalence of Sjogren’s syndrome (SS) and the associated factors in € a sample of the Egyptian population. Methods: This cross-sectional study obtained data by screening subjects from several hospitals in different governorates across Egypt. Demographic and health data were collected including symptoms and type of Sjogren’s syndrome, associated autoimmune diseases, the presence of € specific autoantibodies and associated malignancies. Results: The study analysed 7960 participants and 64 (0.80%) had SS. Of these, 22 (34.38%) had primary SS and 42 patients (65.63%) had secondary SS. For the total study cohort, the prevalence of primary and secondary SS …


Prevalence Profile Of Burning Mouth Syndrome In A Sample Of Egyptian Population: A Cross-Sectional Clinical Based Study, Dalia Ghalwash, Ahmed M. Ammar, Ahmed Hamdy, Ayman Elgawish Oct 2024

Prevalence Profile Of Burning Mouth Syndrome In A Sample Of Egyptian Population: A Cross-Sectional Clinical Based Study, Dalia Ghalwash, Ahmed M. Ammar, Ahmed Hamdy, Ayman Elgawish

Dentistry

Aim: Burning mouth syndrome (BMS) is a debilitating chronic burning sensation in the oral cavity with no identifiable cause. The present research was conducted to evaluate the prevalence profile of BMS in a sample of the Egyptian population. Methods: A cross-sectional study was performed by screening 952 subjects, all individuals with burning mouth complaints were interviewed and examined to identify the site, timing, frequency, and intensity of their burning sensations. The presence of associated xerostomia, taste disturbances, and impact on quality of life was also recorded. The extent of perceived stress was assessed using the short version of the Perceived …


Effect Of Addition Of Metal Oxide Nanoparticles On The Strength Of Heat-Cured Denture Base Resins: Protocol For Systematic Review And Meta-Analysis Of In Vitro Studies, Pragati Kaurani, Amit Hindocha, Amit Porwal, Abhijit Tambe, Carrie Price, Vidhani Goel, Henry Krasner, Jagdish Khubchandani, Kavita Batra Sep 2024

Effect Of Addition Of Metal Oxide Nanoparticles On The Strength Of Heat-Cured Denture Base Resins: Protocol For Systematic Review And Meta-Analysis Of In Vitro Studies, Pragati Kaurani, Amit Hindocha, Amit Porwal, Abhijit Tambe, Carrie Price, Vidhani Goel, Henry Krasner, Jagdish Khubchandani, Kavita Batra

Department of Medical Education Faculty Research

Background: Metal oxide nanoparticle-reinforced polymethyl methacrylate (PMMA) has been shown to improve mechanical properties, such as strength. Different types of metal oxide nanoparticles have been used previously, but the comparative effect on the strength of heat-cured denture base resins remains unclear. Objective: This is a protocol for a systematic review and meta-analysis that will aim to pool evidence to compare and analyze the effects of the addition of different metal oxide nanoparticles, with varied sizes and concentrations, on the strength (flexural, impact, transverse, compressive tensile strength, and fracture toughness) of heat-cured PMMA. In addition, this review aims to analyze methodological …


Pressing Issues For Oral Care Quality Improvement: Findings From The Eu Deliver Project, Paulo Melo, Leonor Frey-Furtado, Daniela Correia, Stefan Listl, Michael Lorenz, Nagihan Bostanci, Álvaro Azevedo, Maria Lurdes Pereira Aug 2024

Pressing Issues For Oral Care Quality Improvement: Findings From The Eu Deliver Project, Paulo Melo, Leonor Frey-Furtado, Daniela Correia, Stefan Listl, Michael Lorenz, Nagihan Bostanci, Álvaro Azevedo, Maria Lurdes Pereira

Faculty, Staff and Student Publications

BACKGROUND: While oral health often takes a backseat to other health domains, it silently affects nearly half of the Worldwide population. The DELIVER project, funded by the EU's Horizon Europe program, seeks to develop a blueprint model for improving the quality of oral health care for everyone.

METHODS: Applying the Nominal Group Technique (NGT), 17 stakeholders from various backgrounds participated in identifying pressing issues for oral care quality improvement across practice, community, and policy levels.

RESULTS: The results revealed significant differences at the different levels, with accessibility emerging as a prominent issue, encompassing affordability, availability, and acceptability of oral healthcare …


A Quantitative Examination Of Tobacco And Marijuana Use On Oral Health Outcomes Among Young Adults In Texas, Meenakshi Dasagi Aug 2024

A Quantitative Examination Of Tobacco And Marijuana Use On Oral Health Outcomes Among Young Adults In Texas, Meenakshi Dasagi

Dissertations and Theses (Open Access)

This dissertation aimed to quantify the relationship between methods of tobacco and marijuana use and their impact on oral health. Tobacco use was defined as smoking combustible tobacco (cigarettes, cigars, and hookah) or electronic aerosolized vaping nicotine with an e-cigarette.5,9 Similarly, marijuana use was defined as smoking combustible marijuana (joints, blunts, and spliffs) or vaping marijuana with an e-cigarette.8 Despite the prevalence of nicotine vaping and marijuana use among young adults1,3-4,7,14-15, there is limited evidence of their association with oral health in Texas. To address this issue, this dissertation comprising three studies analyzed longitudinal data from the Texas Adolescent Tobacco …


Cholesterol Drugs May Improve Periodontal Disease Jul 2024

Cholesterol Drugs May Improve Periodontal Disease

New Orleans Dental Association News

Recently, statin treatment applied locally into tissues during both surgical and nonsurgical procedures exhibiting a positive effect on various parameters of periodontal tissue health. When looking at this novel, not yet commonly utilized approach to the local application of statins as an adjunct to periodontal treatment, early studies have shown significant improvement in clinical parameters, such as probing depth and clinical attachment levels. This method of local statin delivery into the tissue shows promise, and should be explored by further research.


Fake Xanax: Designer Emerging Benzodiazepine Epidemic Linked To Morbidity And Mortality A Narrative Review, Alan D. Kaye, Joseph P. Tassin, William C. Upshaw, Camille M. Robichaux, Mark V. Frolov, Mark M. Dupaquier, Julia E. Fox, Jeffrey Sterritt, Jibin Mathew, Sahar Shekoohi, Adam M. Kaye, Amber N. Edinoff May 2024

Fake Xanax: Designer Emerging Benzodiazepine Epidemic Linked To Morbidity And Mortality A Narrative Review, Alan D. Kaye, Joseph P. Tassin, William C. Upshaw, Camille M. Robichaux, Mark V. Frolov, Mark M. Dupaquier, Julia E. Fox, Jeffrey Sterritt, Jibin Mathew, Sahar Shekoohi, Adam M. Kaye, Amber N. Edinoff

School of Dentistry Faculty Publications

Etizolam is a thienodiazepine derivative which produces an anxiolytic effect similar to benzodiazepines such as alprazolam (Xanax). Like classic benzodiazepines, etizolam has a high affinity towards the GABAA receptor, and allosterically potentiates the effects of GABA resulting in neuronal hyperpolarization related to chloride influx. When taken in therapeutic doses, etizolam produces a similar effect to Xanax. Counterfeit Xanax tablets contain variable amounts of etizolam. Tablets with high amounts of etizolam can cause toxicity if ingested, especially when combined with other substances. When toxic symptoms occur in patients, they may include severe sedation, unconsciousness, and depression of the medullary respiratory center. …


Comorbidities And Final Outcome Of Post Covid-19 Associated Oral Mucormycosis Patients: A Cross-Sectional Study, Dalia Ghalwash, Asmaa Abou-Bakr, Ayman El-Gawish Jan 2024

Comorbidities And Final Outcome Of Post Covid-19 Associated Oral Mucormycosis Patients: A Cross-Sectional Study, Dalia Ghalwash, Asmaa Abou-Bakr, Ayman El-Gawish

Dentistry

Background

Mucormycosis is an invasive and possibly fatal fungal infection that frequently affects the mouth. Co-infection in post COVID-19 patients is an emerging concern, owing to their complex nature and higher mortality. Therefore, this study aimed to report the underlying risk factors, clinical characteristics, presentation, and final outcome of COVID-19 associated oral mucormycosis cases.

Results

This study included 51 patients with oral mucormycosis 28 (55%) males and 23 (45%) females. Twenty-three patients (45%) presented with deep necrotic ulcer, 16 patients (31%) presented with superficial ulcer, and 12 patients (23%) of them presented with fistula. The overall survival rate was 51% …


Dysplasia In Oral Lichen Planus In A Sample Of Egyptians Attending 2 Tertiary Care Centers In Cairo, Dalia Ghalwash, Ayman El-Gawish Jan 2024

Dysplasia In Oral Lichen Planus In A Sample Of Egyptians Attending 2 Tertiary Care Centers In Cairo, Dalia Ghalwash, Ayman El-Gawish

Dentistry

The present retrospective study aimed to evaluate dysplastic changes in oral lichen planus (OLP) lesions and related risk factors in a sample of Egyptians. The records of patients with histological diagnosis of OLP, who attended the Oral Medicine and Periodontology Department, Faculty of Dentistry, Cairo University, and Faculty of Dentistry, the British University in Egypt, in the period from 2020 to 2023 were used. The frequency of dysplasia was 10.19% and was statistically not associated with age, gender or smoking. Our results showed that the erosive type registered the highest rate (p<0.001), followed by atrophic, whereas papular type did not show dysplasia. Also, the most common site for dysplasia was the buccal mucosa and tongue (p<0.001 and p=0.001, respectively), then gingiva, lips, and floor of the mouth. Given the importance of OLP, among the Egyptian population seeking care in our clinics, more research should be conducted to create a database of statistical information.

https://doi.org/10.1111/odi.151


Pdgfra And B Copositive Fibroblasts Drive Fibrosis In Mouse Salivary Glands Through Tgfβ Signaling, Renae Williams Atkinson Jan 2024

Pdgfra And B Copositive Fibroblasts Drive Fibrosis In Mouse Salivary Glands Through Tgfβ Signaling, Renae Williams Atkinson

Electronic Theses & Dissertations (2024 - present)

Fibrosis is of significant concern to the medical community as numerous disease processes are characterized by progressive fibrosis leading to organ damage. We begin the process of examining the mechanism of fibrosis to salivary gland hypofunction and briefly consider Sjögren’s Disease (SjD). Method: We employed single-cell RNA sequencing data from a reversible mouse salivary gland injury model and from NOD/ShiLtJ mice, a model of secondary SjD. We performed treatment comparisons with the help of Seurat dotplots and UMAPS. Using differential gene expression analysis and the publicly available R packages: clusterProfiler, WikiPathways and Cytoscape, we identified the processes and pathways …