Oral Medicine Commons^™

Gentle Beginnings: Innovative Use Of Melatonin And Triclofos Sodium For Uncooperative Children-An Invivo Study, Rohan Shrivastava, Sonal Gupta, Charu Aggarwal, Akil Prawin S.S

International Arab Journal of Dentistry

Objectives: To compare the pre- and post-use of oral melatonin and oral triclofos as oral sedative drugs on anxiety, sedation, and cognitive and psychomotor function to perform satisfactory dental treatment on uncooperative children.

Methods: A total number of 100 patients aged between 4 and 9 years who were scheduled for dental treatment were randomly divided into two groups, Group I and Group II, and administered melatonin and triclofos sodium, respectively, to determine changes in anxiety, cognitive, psychomotor, and sedation scores pre- and post-treatment. Data were analyzed using an unpaired/paired t-test, and P < 0.05 was contemplated as statistically significant.

Results: Post-treatment assessments revealed a significant reduction in …

Artificial Intelligence Versus Human Dental Expertise In Diagnosing Periapical Pathosis On Periapical Radiographs: A Multicenter Study, Fatma E.A Hassanen, Radwa R. Hussein, Mohamed Riad Elgarhy, Shaymaa Mohamed Maher, Marwa Ezz, Ahmed Hassen, Sherif Heidar, Amr Edress, Asmaa Abou-Bakr

Dentistry

Periapical pathosis in periapical radiographs must be properly diagnosed for the success of endodontic treatment but is often muddled by 2D imaging limitations and subjective interpretation. Artificial intelligence (AI) offers a solution, but whether the diagnostic granularity of AI versus human clinicians in everyday clinical practice has been adequately explored remains to be addressed. The purpose of this study was to evaluate the diagnostic accuracy of ChatGPT-5 in detecting periapical radiographic abnormalities compared with the three-expert consensus reference standard. Methods: In this diagnostic accuracy retrospective study, 270 periapical radiographs were independently read by a large language model (ChatGPT-5) and a …

An Art Of Port Wine Birthmark - A Case Report On Type Ii Sturge Weber Syndrome, Dr Sushmitha S, Dr Aravind Warrier S, Dr Dhivya Bharathi

Chulalongkorn Medical Journal

Sturge Weber Syndrome is a Phakomatoses group of neurocutaneous disorders. They manifest in the dermal, neural, ocular, and oral regions due to a mutation in the GNAQ gene. These lesions often are unilateral following the course of the trigeminal nerve.Here we present a case of 54-year-old woman with a history of glaucoma with a unilateral reddish-purple discoloration of the palate and a port-wine stain limited to the left side of her face. The clinical course of Sturge-Weber syndrome is quite complex and necessitates a multidisciplinary approach. In type 2 cases of Sturge-Weber syndrome, patients present with facial angiomas and glaucoma, …

Targeted Injection Therapies For Temporomandibular Joint Disorders: A Comparative Review Of Hyaluronic Acid And Botox Techniques, Timothy Alexander, Marissa Siegel, Noah Schnoor, Elizabeth A. Starns

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

Purpose: This study aimed to evaluate the effectiveness of different injection therapies for temporomandibular joint disorders (TMD) and answer the research question: how do botulinum toxin (onabotulinumtoxinA, Botox) and hyaluronic acid (HA) injections affect symptoms of temporomandibular joint disorder (TMD)? Methods: An electronic search of three databases was performed using the search terms “Treatment of TMD or TMJ” and one of the following: 1) “Hyaluronic Acid Injection” or 2) “Intramuscular Botox Injection”. Based on studies done with human patients, the effects of both hyaluronic acid and Botox injections as treatments for TMD were observed and analyzed. Inclusion criteria were: full …

Systemic Versus Local Injection Of Bone Marrow Mesenchymal Stem Cells On 5-Fluorouracil Treated Parotid Glands Of Albino Rats, Caroline Maged Massieh, Medhat El Zainy, Reham Magdy Amin, Iman Fathy

Dentistry

ABSTRACT Objective: Head and neck cancer is the sixth leading cancer by incidence worldwide and eighth by death. Recent reports revealed that, not only radiotherapy but also chemotherapy may induce xerostomia. The aim of this study was to compare the possible regenerative effect of BMSCs through systemic and local injections. Material and Methods: 52 male Albino rats were randomly divided into 4 groups: Group 1: 10 rats received 0.5 ml of PBS by injection. Group 2: 14 rats received an intraperitoneal injection of 5-FU drug. Group 3: 14 rats were injected the same dose of 5-FU then received an intraglandular …

Identification Of Potential Biomarkers Of Oral Squamous Cell Carcinoma Using Integrated Proteomics And Glycoproteomics And Glycoproteomics Analyses, Yin Ling Wong

Student Works (2020-2029)

Oral cancer is one of the major health concerns worldwide. The 5-year survival rate of oral squamous cell carcinoma (OSCC) has remained at approximately 50% over the past decades. Most OSCCs are diagnosed at an advanced stage due to the delay in diagnosis, suggesting an imperative need in identifying reliable biomarkers to improve the diagnosis, prognosis, and treatment of OSCC. This study aimed to identify potential biomarkers that are involved in the development and progression of OSCC using integrated proteomics and glycoproteomics analyses. Proteomics analysis was performed on serum samples of 10 patients with oral potentially malignant disorder (OPMD), 40 …