Open Access. Powered by Scholars. Published by Universities.®
- Keyword
- Publication Type
Articles 1 - 2 of 2
Full-Text Articles in Oral Medicine
Identification Of Serum Anti-Carbamylated Protein Antibodies In Rheumatoid Arthritis Patients With Periodontitis: A Pilot Study, Shruthi Venu Gopal
Identification Of Serum Anti-Carbamylated Protein Antibodies In Rheumatoid Arthritis Patients With Periodontitis: A Pilot Study, Shruthi Venu Gopal
Student Works (2020-2029)
Objectives: In chronic diseases such as rheumatoid arthritis (RA), carbamylation may cause the production of autoantibodies such as the anti-carbamylated protein antibody (anti-CarP) and protein malfunctioning. However, its relation to periodontitis (PD) remains unclear. Therefore, this study aimed to assess the serum levels of anti-carbamylated protein antibodies (anti-CarP) in four groups of participants, the RAPD, RA, PD, and healthy groups and correlate the findings with rheumatological parameters. Materials and methods: This pilot study included a total of 20 participants, with 5 participants each in groups diagnosed with RA and PD (RAPD), only RA, only PD and controls who were free …
Gingival Transcriptome Of Innate Antimicrobial Factors And The Oral Microbiome With Aging And Periodontitis, Jeffrey L. Ebersole, Sreenatha Kirakodu, Linh Nguyen, Octavio A. Gonzalez
Gingival Transcriptome Of Innate Antimicrobial Factors And The Oral Microbiome With Aging And Periodontitis, Jeffrey L. Ebersole, Sreenatha Kirakodu, Linh Nguyen, Octavio A. Gonzalez
Dental Medicine Faculty Research
The epithelial barrier at mucosal sites comprises an important mechanical protective feature of innate immunity, and is intimately involved in communicating signals of infection/tissue damage to inflammatory and immune cells in these local environments. A wide array of antimicrobial factors (AMF) exist at mucosal sites and in secretions that contribute to this innate immunity. A non-human primate model of ligature-induced periodontitis was used to explore characteristics of the antimicrobial factor transcriptome (n = 114 genes) of gingival biopsies in health, initiation and progression of periodontal lesions, and in samples with clinical resolution. Age effects and relationship of AMF to the …