Oral Medicine Commons^™

Minimally Invasive Decompression And Long-Term Follow-Up Of An Orthokeratinized Odontogenic Cyst Of The Mandible: A 7-Year Case Report, Akram Belmehdi, Karima El Harti

International Arab Journal of Dentistry

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Introduction: Orthokeratinized odontogenic cyst (OOC) is a rare developmental jaw lesion with indolent behavior and low recurrence potential.

Case presentation: A 33-year-old healthy male was referred after incidental discovery of a mandibular radiolucency. Cone-beam CT revealed a well-defined unilocular lesion in close relation to the inferior alveolar canal. Aspiration confirmed its cystic nature, and a conservative decompression was performed using a rubber drain to reduce lesion size and preserve adjacent structures. Histopathologic examination identified orthokeratinized epithelium consistent with OOC. After seven months of decompression, the lesion showed marked ossification, allowing safe enucleation and peripheral curettage. Radiographic follow-ups at 19 months …

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Efficacy Of Autologous Platelet-Rich Fibrin (Prf) In Promoting Soft Tissue Healing And Bone Regeneration Following Extraction In The Anterior Maxilla: A Digital And Radiological Study, Anthony El Rai, Abdallah Menhall, Joseph Zaarour, Robin Jalkh, Joseph Bassil

International Arab Journal of Dentistry

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Objectives: The main objective of this study was to evaluate the effectiveness of PRF in promoting soft tissue healing and bone regeneration after extraction in the anterior maxillary region. A secondary objective was to correlate soft tissue change with underlying bone structure variation. Finally, the study also aimed to compare soft and hard tissue alteration based on different types of extracted teeth.

Methods: The sample included five adult patients requiring the extraction of at least two symmetrical teeth in the anterior maxilla, totaling fourteen teeth. Participants underwent CBCT scans and digital impressions before extraction. Concerned teeth were then …

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Self-Medication Behavior Of Dental Students With Oral Ulceration Lesions: A Cross-Sectional Study In Yogyakarta, Indonesia, Fita Fathaya Iriana, Hendri Susanto, Rosa Amalia

Journal of Dentistry Indonesia

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Objective: Self-medication refers to medication behavior for self-diagnosed symptoms. Oral ulcers are self-medicated lesions in the oral cavity. Dental students have different knowledge about oral cavity lesions and may self-medicate using drugs. This study aimed to determine the self-medication behavior of dental students for oral ulcers. Methods: This cross-sectional study was conducted on dental students in the Faculty of Dentistry from different batch years. Purposive sampling was used to select students with oral ulcer lesions in the last six months. A validated and reliable questionnaire was used to assess self-medication behavior. Data collection using the online form. Student behavior …

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Temporomandibular Joint Osteoarthritis And Systemic Inflammation: A Cadaveric Study For Dental Insights, Nathan Kent Bs, David Patterson Bs, Alyssa Luu Bs, Samantha Pipkin Bs, Jason Ciccotelli Dpt, Phd, Jeremy James Dmd, Ms, Jessica Immonen Phd, Ms

The Journal of Integrative Physiology

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The objective of this study was to determine if gross signs of cadaveric osteoarthritis (OA) have

a tendency to present systemically and if this presentation includes pathology found at the

temporomandibular joint (TMJ). Signs of OA were then correlated to gross alterations of the aorta and common carotid arteries seen with atherosclerotic cardiovascular disease. Ipsilateral synovial joints including the TMJ, knee joint, radiocarpal joint and trapeziometacarpal (TMC) joint were all assessed for signs of OA in 4 cadaveric donors (3 males; 72, 82 and 92 years-old / 1 female; 89 years-old) using a validated scale of disease severity. A Grade …

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Oral Cancer And The Impact Of Glossectomy: Challenges And Pathways To Recovery, Merna Roman, Kamran H. Awan

Annual Research Symposium

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No abstract provided.

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Pdgfra And B Copositive Fibroblasts Drive Fibrosis In Mouse Salivary Glands Through Tgfβ Signaling, Renae Williams Atkinson

Electronic Theses & Dissertations (2024 - present)

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Fibrosis is of significant concern to the medical community as numerous disease processes are characterized by progressive fibrosis leading to organ damage. We begin the process of examining the mechanism of fibrosis to salivary gland hypofunction and briefly consider Sjögren’s Disease (SjD). Method: We employed single-cell RNA sequencing data from a reversible mouse salivary gland injury model and from NOD/ShiLtJ mice, a model of secondary SjD. We performed treatment comparisons with the help of Seurat dotplots and UMAPS. Using differential gene expression analysis and the publicly available R packages: clusterProfiler, WikiPathways and Cytoscape, we identified the processes and pathways …

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Functional Significance Of Senescence And Autophagy In Cancer-Associated Fibroblasts From Oral Squamous Cell Carcinoma, May Leng Tan

Student Works (2020-2029)

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Oral squamous cell carcinoma (OSCC) is a malignancy that arises from the epithelial cells within the oral cavity. It accounts for approximately 355,000 new cases worldwide and is exceptionally prevalent in particular geographical areas such as Papua New Guinea, the Indian subcontinent and South-East Asian countries. Despite advances in surgical management and therapeutic approaches, the five-year survival rate of OSCC patients has not improved significantly over the past few decades. The mortality associated with OSCC is particularly high often due to late presentation, locoregional recurrence, distant metastases and the development of second primary tumours. A comprehensive understanding of the molecular …

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Anticancer Activity Of Ficus Deltoidea And Tualang Honey On Oral Cancer Cells: An In Vivo Study, Alkoshab May Ameen Saeed

Student Works (2020-2029)

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The use of natural products have been gaining interest, notably in the area of cancer therapy and in this study, natural products rich in antioxidants such as Tualang Honey (Malaysian wild local honey) and Ficus deltoidea (Malaysian local herbal plant), were selected to assess their chemo-preventive and chemotherapeutic activities on oral cancer. The aim of this study is to evaluate the chemo-preventive and chemotherapeutic activities of Ficus deltoidea (FD) and Tualang Honey (TH) in an animal model induced for oral cancer using 4-Nitroquinoline1-oxide (4NQO). A total of 70 male Sprague-Dawley (SD) rats were distributed into ten groups (n=7 per group); …

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Expression Of Ki-67, Fscni And Tnfrsf 12a In Histologically Non-Involved Mucosal Surgical Margins As Predictive Markers For Local Relapse In Oral Squamous Cell Carcinoma, Zainul Abidin Nur Fauziani

Student Works (2020-2029)

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Introduction: The presence tumour-related genetic alterations in histologically noninvolved mucosal surgical margins was linked to development of local relapse in OSCC. Aims: The present study aimed to determine the association between expression of Ki67, FSCN1 and TNFRSF12A in histologically non-involved mucosal surgical margins of OSCC patients and local relapse. Materials and methods: The study involved a total of 34 OSCC cases including 15 cases of patients who had relapse within the 5 years followup period and 19 cases of patients who did not had relapse. Two-stage sampling was carried out to select the margins’ site, followed by the representative sections …

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Differential Expression Of Mucin In Salivary Gland Tumours, Mahamad Apandi Nurul Inaas

Student Works (2020-2029)

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Introduction: Varied alterations in types of secreted mucin may affect the regulation of cell growth, immune response and adhesion of cell. These changes may indirectly contribute to the ability of tumour invasion and metastasis. However, the expression of mucins in salivary gland tumours has not been explored in depth. Objectives: To investigate expressions of mucin in the salivary gland tumour microenvironment and make comparisons between benign and malignant, and minor and major salivary gland tumours. Methods: Special stains were used to stain neutral mucin (Periodic acid Schiff), sialomucin (Alcian Blue) and sulfomucin (Aldehyde Fuschin) within tissues from 6 normal salivary …

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Expert Search For The "Effect Of Dental Treatment Before Cardiac Valve Surgery", Kelly K. O'Brien

Expert Search Strategies

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This search strategy was constructed to support the research for the peer reviewed article listed above. Full article abstract:

Background

The purpose of this systematic review was to determine the potential effect of dental treatment before cardiac valve surgery (CVS) or left ventricular assist device (LVAD) implantation on morbidity and mortality.

Types of Studies Reviewed

The authors included relevant studies from MEDLINE, Embase, and the Cochrane Central Register of Controlled Trials, including randomized controlled trials and cohort studies, published from 1998 through 2019 and involving adults who received dental treatment before CVS or LVAD implantation. The authors assessed bias by …

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