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Full-Text Articles in Oral Medicine
Polymicrobial Interactions Between Selected Microbes Of Oral Biofilm And Differential Expression Of Als Genes And Their Related Proteins, Fahim Ayesha
Student Works (2020-2029)
More than 700 different types of microorganisms dwell in human oral mucosal surfaces. The interactions between these microorganisms contribute to formation of polymicrobial communities on hard and soft tissues as well as on dentures and implants. Candida albicans, a pleomorphic fungus inhabiting oral and gastrointestinal (GIT) mucosa becomes pathogenic in favourable conditions causing local or systemic disease. Since streptococci are early colonisers, the ability of Candida albicans to adhere to streptococci paves the way for an additional surface for candidal colonization and propagation. This study was aimed to investigate polymicrobial interactions between C. albicans, S. sanguinis and S. mitis on …
Functional Significance Of Senescence And Autophagy In Cancer-Associated Fibroblasts From Oral Squamous Cell Carcinoma, May Leng Tan
Functional Significance Of Senescence And Autophagy In Cancer-Associated Fibroblasts From Oral Squamous Cell Carcinoma, May Leng Tan
Student Works (2020-2029)
Oral squamous cell carcinoma (OSCC) is a malignancy that arises from the epithelial cells within the oral cavity. It accounts for approximately 355,000 new cases worldwide and is exceptionally prevalent in particular geographical areas such as Papua New Guinea, the Indian subcontinent and South-East Asian countries. Despite advances in surgical management and therapeutic approaches, the five-year survival rate of OSCC patients has not improved significantly over the past few decades. The mortality associated with OSCC is particularly high often due to late presentation, locoregional recurrence, distant metastases and the development of second primary tumours. A comprehensive understanding of the molecular …