Dentistry Commons^™

Oral Mucositis: The New Paradigms, Rajesh V. Lalla, Douglas E. Peterson

UCHC Articles - Research

Purpose of review

Mucositis has long been viewed as an unavoidable consequence of high-dose chemotherapy and/or radiation. Management has been directed to supportive care including oral pain control, nutritional support, infection treatment and control of diarrhea. While these interventions have been valuable for clinical management, they have not been collectively directed to molecularly targeted prevention and treatment. This review addresses recent advances regarding mucosal injury in cancer patients, with emphasis on symptom clusters, genetically-based tissue susceptibility and risk prediction, imaging technology, and computational biology.

Recent findings

Modeling of symptom clusters in cancer patients continues to mature. Although integration of mucositis …

Loma Linda University Dentistry - Volume 21, Number 02, Loma Linda University School Of Dentistry

Articulator (Dentistry)

Contents:

6 | Theodorou Farewell

11 | 2010 Commencement

17 | Orthodontics History

26 | Alumni Student Homecoming

30 | PNAM's Cleft Lip Angels

37 | DPRK Historic Guests

44 | Student Research Winners

Professional Product Review Vol. 5 No. 3, American Dental Association, Council On Scientific Affairs

Professional Product Review

A user-friendly newsletter from the ADA Council on Scientific Affairs offering scientifically sound, unbiased, and clinically relevant information to member dentists about professional dental products tested by the ADA. This collection is historical and may not reflect current standards. For up-to-date information contact the ADA.

Provision Of Fluoride Varnish Treatment By Medical And Dental Care Providers: Variation By Race/Ethnicity And Levels Of Urban Influence, Christopher Okunseri, Aniko Szabo, Raul I. Garcia, Scott Jackson, Nicholas M. Pajewski

School of Dentistry Faculty Research and Publications

Objective: In 2004, Wisconsin Medicaid policy changed to allow medical care providers to be reimbursed for fluoride varnish treatment (FVT) to children's teeth to improve access and utilization. To date, no study has been published on whether geographic and racial/ethnic variation in the provision of FVT in response to this policy change exists. This study's objective is to examine the association of rates of FVT for children enrolled in Wisconsin Medicaid with race/ethnicity, urban influence codes (UIC), and dental health professional shortage area (DHPSA) designation based on county of residence.

Methods: A retrospective, pre–post design was used based on FVT …

Influence Of Blood Contamination On Bond Strength Of A Self-Etching System, Ellen Cristina De Carvalho Mendonça, Samuel Nilo Vieira, Fernando Aparecido Kawaguchi, John Powers, Adriana Bona Matos

Faculty, Staff and Student Publications

OBJECTIVES: To detect the influence of blood contamination (BC) on the bond strength (BS) of a self-etching bonding system (SES) to enamel and dentine.

METHODS: 25 human molars were longitudinally sectioned on the mesio-distal axis in order to obtain 50 specimens, which were embedded in acrylic resin. At first, the specimens were ground to expose a flat surface of enamel, and a bond strength test was performed. Afterwards, the samples were ground again in order to obtain a flat surface of dentine. Ten groups (total: n=100) were assigned according to substrate (enamel and dentine), step in the bonding sequence when …

Soft Tissue Profile Response In Extraction Versus Non-Extraction Orthodontic Treatment, Munizeh Khan, Mubassar Fida

Section of Dental-Oral Maxillofacial Surgery

Objective: To compare changes occurring in the soft tissue profile with orthodontic treatment in extraction versus nonextraction cases, and to determine the hard and soft tissue parameters that show significant correlations to understand the factors influencing the response to tooth movement. Study Design: Quasi-experimental. Place and Duration of Study: Dental Section, The Aga Khan University Hospital, Karachi, from 2005 to 2008. Methodology: Pre- and post-treatment lateral cephalographs of 34 subjects were assessed. For half of the patients (n=17), treatment included the extraction of 4 premolars, whereas the other half were treated by the non-extraction approach. Incisal and soft tissue effects …

The Prevalence Of Maxillary Altered Passive Eruption In A Dental School Population., Francisco Carlos

Theses and Dissertations

AIM: The aim of this investigation is to determine the prevalence of maxillary altered passive eruption in a dental school population. METHODS: 100 subjects were examined clinically and had models fabricated of their maxilla. Demographic, periodontal, cast measurements were recorded for each subject. Demographic variables recorded included age, gender, and ethnicity, history of orthodontic treatment, presence of incisal /occlusal wear, appearance of gingival excess, and presence of gingival asymmetry. Measurements made on cast included clinical crown length, clinical crown width, papillary height, and distance from the lateral gingival zenith to the gingival aesthetic line. Clinical crown width-to-length ratio was calculated. …

Perception Of Soft Tissue Laser Use In Orthodontic Practice: A Survey Of Orthodontists, Periodontists, And General Dentists, Brandon Burke

Theses and Dissertations

Recently, soft tissue lasers have been introduced into orthodontic practice to perform procedures that were traditionally referred to other dental professionals. The purpose of this study was to compare the attitudes of orthodontists, periodontists, and general dentists regarding the use of soft tissue lasers by orthodontists. The ultimate goal was to facilitate communication among dental professionals and improve the care of orthodontic patients requiring management of soft tissues. A survey was developed to evaluate and compare the current opinions of orthodontists (n=330), periodontists (n=171), and general dentists (n=77) regarding orthodontists’ use of soft tissue lasers. When compared to orthodontists and …

Ada News - 06/21/2010, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Ada News - 06/07/2010, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Characterization Of Stem And Progenitor Cells In The Dental Pulp Of Erupted And Unerupted Murine Molars, Anamaria Balic, Hector L. Aguila, Melissa J. Caimano, Victor P. Francone, Mina Mina

UCHC Articles - Research

In the past few years there have been significant advances in the identification of putative stem cells also referred to as “mesenchymal stem cells” (MSC) in dental tissues including the dental pulp. It is thought that MSC in dental pulp share certain similarities with MSC isolated from other tissues. However, cells in dental pulp are still poorly characterized. This study focused on the characterization of progenitor and stem cells in dental pulps of erupted and unerupted mice molars. Our study showed that dental pulps from unerupted molars contain a significant number of cells expressing CD90+/CD45-, CD117+/CD45-, Sca-1+/CD45- and little if …

Contact Point, Arthur A. Dugoni School Of Dentistry

Contact Point

No abstract provided.

Ethics, Empathy, And The Education Of Dentists, David A. Nash

Oral Health Science Faculty Publications

Professional education in dentistry exists to educate good dentists-dentists equipped and committed to helping society gain the benefits of oral health. In achieving this intention, dental educators acknowledge that student dentists must acquire the complex knowledge base and the sophisticated perceptual-motor skills of dentistry. The graduation of knowledgeable and skilled clinicians in dentistry is a necessary, but not sufficient, condition for ensuring quality oral health care. The further requirement is the commitment of graduates to applying their abilities with moral integrity: providing appropriate and quality care in their patients' best interest. Ultimately, good dentistry depends on individuals committed to treating …

Effect Of Low-Magnitude, High-Frequency Vibration On Osteocytes In The Regulation Of Osteoclasts, Esther Lau, Saja Al-Dujaili, Axel Guenther, Dawei Liu, Liyun Wang, Lidan You

School of Dentistry Faculty Research and Publications

Osteocytes are well evidenced to be the major mechanosensor in bone, responsible for sending signals to the effector cells (osteoblasts and osteoclasts) that carry out bone formation and resorption. Consistent with this hypothesis, it has been shown that osteocytes release various soluble factors (e.g. transforming growth factor-β, nitric oxide, and prostaglandins) that influence osteoblastic and osteoclastic activities when subjected to a variety of mechanical stimuli, including fluid flow, hydrostatic pressure, and mechanical stretching. Recently, low-magnitude, high-frequency (LMHF) vibration (e.g., acceleration less than < 1 × g, where g = 9.81 m/s², at 20–90 Hz) has gained much interest as studies …

Amelioration Of Oral Mucositis Pain By Nasa Near Infra Red Light Emitting Diodes In Bone Marrow Transplant Patients (Poster), Brian D. Hodgson, David Margolis, L D. Williams, D E. Salzman, J E. Sande, W P. Vaughan, Harry T. Whelan

School of Dentistry Faculty Research and Publications

No abstract provided.

Commencement Program 2010, Loma Linda University

Commencement Programs

CONTENTS

1 | Message from the President

3 | 2010 Events of Commencement

4 | The Academic Procession

6 | Significance of Academic Regalia

8 | The Good Samaritan

9 | University History Highlights

11 | Loma Linda University Song - "Healing Love"

12 | The Speakers

22 | The University Honorees

36 | The School Honorees

59 | The Programs

• School of Medicine, 60
• School of Pharmacy, 77
• School of Dentistry, 83
• School of Science and Technology and School of Religion, 99
• School of Nursing, 112
• School of Allied Health Professions - Physical Therapy, 121
• School of Allied Health …

The Human Oral Microbiome Database: A Web-Accessible Resource For Investigating Oral Microbe Taxonomic And Genomic Information, Tsute Chen, Wen-Han Yu, Jacques Izard, Oxana V. Baranova, Abirami Lakshmanan, Floyd E. Dewhirst

Department of Food Science and Technology: Faculty Publications

The human oral microbiome is the most studied human microflora, but 53% of the species have not yet been validly named and 35% remain uncultivated. The uncultivated taxa are known primarily from 16S rRNA sequence information. Sequence information tied solely to obscure isolate or clone numbers, and usually lacking accurate phylogenetic placement, is a major impediment to working with human oral microbiome data. The goal of creating the Human Oral Microbiome Database (HOMD) is to provide the scientific community with a body site-specific comprehensive database for the more than 600 prokaryote species that are present in the human oral cavity …

12th Annual Pacific Research Day Abstracts, University Of The Pacific

Excellence Day

No abstract provided.

Ada News - 05/17/2010, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Efficacy Of Orthodontic Bonding Agents In Preventing Demineralization Around Brackets, Morris Poole

Theses and Dissertations

Enamel demineralization is a concern in orthodontic patients with poor oral hygiene. To curtail this problem, amorphous calcium phosphate (ACP) containing adhesives have been developed. The purpose of this in vitro study was to evaluate the cariostatic potential of an ACP containing orthodontic bonding agent adjacent to brackets. Sixty human molars were randomly distributed into: ACP adhesive, resin modified glass ionomer cement (RMGIC), and conventional composite resin groups (N=20 each). Brackets were bonded following the manufacturer’s instructions. Tooth enamel through a 2mm window around the brackets was cycled in demineralization (6 hrs) and remineralization (18 hrs) solutions. After 14 days, …

Self-Ligating Vs. Conventional Brackets As Perceived By Orthodontists, Chase Prettyman

Theses and Dissertations

Introduction: Within the past decade, significant developments, new designs, and numerous proposed advantages of self-ligating (SL) brackets have caused them to gain great popularity among practicing orthodontists. The purpose of this study was to determine if there are significant clinical differences between SL and conventional brackets on orthodontic treatment as perceived by practicing orthodontists, and more specifically, if the proposed advantages of SL brackets are evident in clinical practice. Methods: A survey was developed to evaluate how SL brackets compare to conventional brackets when perceived by practicing orthodontists (n=430). The initial series of questions focused on individual practitioner characteristics and …

Lip Profile Preferences Of Asian Americans, Hung Quoc Lu

Theses and Dissertations

The aim of this study was to evaluate how Asians, non-Asians, and orthodontists in America view esthetic soft tissue Asian lip profiles. The null hypothesis was that there was no difference in the perception of lip profile esthetics of Asian patients between Asian laypersons, non-Asians laypersons, and orthodontists. A survey was constructed using the profile photographs of one adult male and one adult female Asian American patient taken from the VCU Orthodontics Clinic records. Using Dolphin Imaging 3D, the original photographs were digitally altered. The lips in each photograph were moved in increments forward and backwards to produce 5 images …

Use Of Cone Beam Computed Tomography In The Determination Of Mental Foramen Location In Relation To Mandibular 1st And 2nd Premolars, Sanjay Bhagchandani

Theses and Dissertations

The purpose of this study was to use existing Cone Beam Computer Tomography images to determine the vertical and horizontal location of the mental foramen in relation to the mandibular first and second premolars, as well as the distance in millimeters from the apex of each. The distance from the inferior border of the foramen to the inferior border of the mandible was also recorded. The average distance from the apices of the mandibular first and second premolars to the mental foramen was 7.43mm (SD= 1.97) and 5.30mm (SD=1.65) respectively. The foramen was located 11.44mm (SD=1.49) from the inferior border …

Endodontic Residents’ Understanding Of Biostatistics: A 2010 Survey Of Endodontic Residents In The United States, Paul Letellier Jr.

Theses and Dissertations

Endodontic residents must keep current with clinical information to practice evidence- based dentistry. To do so, endodontic residents must access research papers and interpret results. This requires a knowledge of biostatistics. However, the biostatistical knowledge of endodontic residents is relatively unknown. The purpose of the study was to assess the biostatistical knowledge of endodontic residents using a survey instrument to prove or reject the hypothesis that there exists a lack of understanding of biostatistic principles among endodontic residents. A survey consisting of 29 questions querying attitudes and biostatistical knowledge was distributed to 230 endodontic residents and returned with a 32% …

Endodontic Education And Educators: Who Is Teaching Our Predoctoral Students And What Methods Are Being Taught?, Ellison Turner

Theses and Dissertations

A survey was conducted to assess the current state of predoctoral endodontic education in the United States. Fifty-one schools received surveys and 73% responded. Seventy-six percent were from public schools with most having a graduate endodontic program (84%). Preclinical training most often began in the spring of second year and clinical training started in the fall of third year (each 54%). All programs that responded stated that endodontists routinely instruct students in the clinic. Sodium hypochlorite 2.5% was the irrigation of choice. Calcium hydroxide was the most common intracanal medicament. Cold lateral condensation with gutta-percha was the most frequently indicated …

Ada News - 05/03/2010, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Shear-Peel Bond Strength Of Metal Bracket To Porcelain Surface Treated With 1.23% Acidulated Phosphate Fluoride Gel, Suchon Vatarugegrid, Smorntree Viteporn

Chulalongkorn University Dental Journal

Objective The purpose of this study was to compare the shear-peel bond strength of metal bracket to the prepared porcelain surface with two different surface preparations; silane and 1.23% acidulated phosphate fluoride (APF) gel. Materials and methods The samples were comprised of 60 porcelain disks (diameter 10 mm, thickness 4 mm). All were unglazed with green stones and then were randomly assigned into 2 groups (30 specimens each). Group 1 (control), the porcelain surface was prepared with silane. Group 2, the porcelain surface was etched with 1.23% APF gel for 10 minutes. A central incisor metal bracket was bonded to …

Preliminary Study Of Effects Of A Standardized Extract Of Centella Asiatica Eca 233 On Minor Aphthous Ulcers, Chalandakorn Ruengprasertkit, Naulchavee Hongprasong, Boonyong Tantisira, Mayuree H. Tantisira

Chulalongkorn University Dental Journal

Objective The present pilot study aimed to investigate the effects of a standardized extract of Centella asiatica ECa 233 on an oral paste form on minor recurrent aphthous ulceration (MiRAU). Materials and methods A randomized, single-blind, placebo controlled trial was conducted on 24 eligible subjects with MiRAU and randomly divided into four groups: 0.05, 0.10 and 0.20% ECa 233 paste and placebo oral paste. On entry to the trial at day 0, subjects were instructed to apply the oral paste three times per day (after breakfast and lunch and at bedtime) for 10 days or until the ulcer was completely …

ผลของควันบุหรี่และสารทําความสะอาดฟันเทียมต่อความแข็งผิวและสีของผิวเคลือบเรซินอะคริลิก, ณัฐวรรธน์ ปลื้มสําราญ, รุ่งอรุณ อภินันทน์, พนารัตน์ ขอดแก้ว, ปิยวัฒน์ พันธุ์โกศล

Chulalongkorn University Dental Journal

วัตถุประสงค์ เพื่อศึกษาผลของควันบุหรี่และสารทําความสะอาดฟันเทียมที่มีต่อสีและความแข็งผิวของเรซินอะคริลิก ที่ใช้และไม่ใช้สารเคลือบผิว วัสดุและวิธีการ เตรียมชิ้นงานเรซินอะคริลิกขนาด 15x15x3 มิลลิเมตร จํานวน 200 ชิ้น แบ่งเป็น 4 กลุ่ม โดย เตรียมผิวแตกต่างกัน ได้แก่ เรซินอะคริลิกที่ขัดด้วยแท่งไขขัดมันเพื่อใช้เป็นกลุ่มควบคุม และกลุ่มที่เคลือบผิวด้วย บอสเวิร์ธเกลซ พาลาซีล และพลาควิต ทําการวัดสีและความแข็งผิวก่อนและหลังจากอบควันบุหรี่ หลังจากนั้น แบ่งชิ้นงานแต่ละกลุ่มให้เป็น 5 กลุ่มย่อย สําหรับการแช่ในน้ําและสารทําความสะอาดฟันเทียมสี่ชนิด คือโบนีพลัส ฟิตตี้เดนท์ โพลิเดนต์ และสเตอราเดนต์ แล้ววัดสีและความแข็งผิวอีกครั้ง วิเคราะห์ข้อมูลทางสถิติโดยใช้การ วิเคราะห์ความแปรปรวนแบบทางเดียว และการวิเคราะห์ความแปรปรวนแบบสองทาง สําหรับวิเคราะห์ผลต่างของ สีภายหลังอบควัน และภายหลังแช่สารทําความสะอาดฟันเทียมตามลําดับ โดยใช้การเปรียบเทียบเชิงซ้อนแบบแทมเฮน และใช้การทดสอบผลต่างค่าเฉลี่ยแบบจับคู่ในการวิเคราะห์ความแข็งผิว ทดสอบที่ระดับนัยสําคัญ 0.05 ผลการศึกษา หลังจากอบควันบุหรี่เรซินอะคริลิกที่ใช้สารเคลือบผิวทุกกลุ่มมีการติดสีน้อยกว่ากลุ่มควบคุมอย่างมี นัยสําคัญทางสถิติ ในขณะที่การแช่ในสารละลายใด ๆ ไม่มีผลต่อการติดสี ยกเว้นกลุ่มควบคุมเมื่อแช่ในน้ํา จะมีการเปลี่ยนสีมากอย่างมีนัยสําคัญทางสถิติ สําหรับค่าความแข็งผิวพบว่าสารเคลือบผิวพลาดวิตให้ความแข็งผิวสูง ที่สุด ขณะที่สารเคลือบผิวบอสเวิร์ธเกลซให้ความแข็งผิวต่ําที่สุด และเมื่อนําชิ้นตัวอย่างมาอบควันบุหรี่และแช่สารทําความสะอาดฟันเทียมแล้ว กลุ่มที่ใช้สารเคลือบผิวทุกกลุ่มรวมทั้งกลุ่มควบคุมมีความแข็งผิวเปลี่ยนแปลง ยกเว้นกลุ่มที่เคลือบด้วยพาลาซีลที่มีค่าความแข็งผิวไม่แตกต่างจากตอนเริ่มต้น สรุป การอบควันบุหรี่ทําให้เรซินอะคริลิกที่ขัดด้วยแท่งไขขัดมันมีการติดสีมากกว่ากลุ่มที่ใช้สารเคลือบผิวแช่สารทําความสะอาดฟันเทียมทุกชนิดในทุกกลุ่มที่ใช้สารเคลือบผิว ให้ผลการติดสีไม่แตกต่างกัน นอกจากนี้สารเคลือบผิวทําให้ความแข็งผิวของเรซินอะคริลิกเปลี่ยนแปลงทั้งก่อนและหลังจากแช่สารทําความสะอาดฟันเทียมด้วย (ว ทันต จุฬาฯ 2553;33:77-88)

ความก้าวหน้าของงานวิจัยวิศวกรรมเนื้อเยื่อฟัน:บทวิจารณ์, ธนภูมิ โอสถานนท์

Chulalongkorn University Dental Journal

วิศวกรรมเนื้อเยื่อของฟันทั้งเพื่อใช้ในการปลูกถ่ายทดแทนฟันธรรมชาติที่สูญเสียไป เป็นเทคนิคที่ถูกคาดหวังที่จะใช้ในการรักษาในคลินิกในอนาคต แม้ว่าในปัจจุบันยังมีข้อจํากัดอยู่มากในแง่ของคุณสมบัติทั้งทางกายภาพและชีวภาพที่จะพัฒนาการสร้างฟันขึ้นในห้องปฏิบัติการเพื่อใช้ในวัตถุประสงค์นี้ แต่อย่างไรก็ตามได้มีรายงานวิจัย เกี่ยวกับการวิศวกรรมเนื้อเยื่อของฟันที่น่าสนใจตีพิมพ์ลงในวารสาร Proceedings of the National Academy of Sciences USA บ่งบอกถึงศักยภาพของนักวิทยาศาสตร์ในการพัฒนางานด้านนี้ให้สามารถใช้ได้จริงในอนาคตบทความนี้มีวัตถุประสงค์เพื่อสรุปสาระสําคัญและวิจารณ์งานวิจัยนี้ เพื่อให้ทราบถึงความก้าวหน้าของงานวิศวกรรมเนื้อเยื่อของฟันในปัจจุบัน (2 ทันต จุฬาฯ 2553;33:143-48)