Dentistry Commons^™

Xenograft Tumors Vascularized With Murine Blood Vessels May Overestimate The Effect Of Anti-Tumor Drugs: A Pilot Study, Zhihong Dong, Atsushi Imai, Sudha Krishnamurthy, Zhaocheng Zhang, Benjamin David Zeitlin, Jacques E. Nör

All Dugoni School of Dentistry Faculty Articles

Recent evidence demonstrated that endothelial cells initiate signaling events that enhance tumor cell survival, proliferation, invasion, and tumor recurrence. Under this new paradigm for cellular crosstalk within the tumor microenvironment, the origin of endothelial cells and tumor cells may have a direct impact on the pathobiology of cancer. The purpose of this pilot study was to evaluate the effect of endothelial cell species (i.e. murine or human) on xenograft tumor growth and response to therapy. Tumor xenografts vascularized either with human or with murine microvascular endothelial cells were engineered, side-by-side, subcutaneously in the dorsum of immunodefficient mice. When tumors reached …

Antimicrobial Peptide Coating Of Dental Implants: Biocompatibility Assessment Of Recombinant Human Beta Defensin-2 For Human Cells, Patrick Warnke, Eske Voss, Paul Russo, Sebastien Stephens, Michael Kleine, Hendrik Terheyden, Qin Liu

Qin Liu

Purpose: Artificial materials such as dental implants are at risk of bacterial contamination in the oral cavity. Human beta defensins (HBDs), small cationic antimicrobial peptides that exert a broad-spectrum antibacterial function at epithelial surfaces and within some mesenchymal tissues, could probably help to reduce such contamination. HBDs also have protective immunomodulatory effects and have been reported to promote bone remodeling. The aim of this study, therefore, was to investigate the influence of recombinant HBD-2 on the proliferation and survival of cells in culture.

Materials and Methods: Human mesenchymal stem cells (hMSCs), human osteoblasts, human keratinocytes (control), and the HeLa cancer …

Glass-Ceramics For Non-Metallic Dental Implant Applications, Selma Saadaldin

Electronic Thesis and Dissertation Repository

Metallic dental implants are an important treatment for the replacement of missing teeth. However, for esthetic and environmental issues, there is a need to develop non-metallic dental implant materials. In this thesis, two novel glass-ceramics (GCs), miserite and wollastonite, were synthesized for one-piece dental implant applications. Glasses were synthesized by wet chemical methods, followed by calcination, melting and quenching. The crystallization kinetics of these glasses were determined by differential thermal analysis (DTA). GC specimens were produced by cold pressing of the glass powder and sintering using schedules determined by DTA. The crystalline phases and microstructure of the GC samples were …

Comparison Of In Vitro Biocompatibility Of Nanobone(®) And Biooss(®) For Human Osteoblasts, Qin Liu, Timothy Douglas, Christiane Zamponi, Stephan Becker, Eugene Sherry, Sureshan Sivananthan, Frauke Warnke, Jörg Wiltfang, Patrick Warnke

Qin Liu

Introduction:Scaffolds for bone tissue engineering seeded with the patient's own cells might be used as a preferable method to repair bone defects in the future. With the emerging new technologies of nanostructure design, new synthetic biomaterials are appearing on the market. Such scaffolds must be tested in vitro for their biocompatibility before clinical application. However, the choice between a natural or a synthetic biomaterial might be challenging for the doctor and the patient. In this study, we compared the biocompatibility of a synthetic bone substitute, NanoBone®, to the widely used natural bovine bone replacement material BioOss®.Material and methods: The in …

Proliferation Assessment Of Primary Human Mesenchymal Stem Cells On Collagen Membranes For Guided Bone Regeneration, Qin Liu, A. Humpe, D. Kletsas, F. Warnke, S. Becker, T. Douglas, S. Sivananthan, P. Warnke

Qin Liu

Purpose: Human mesenchymal stem cells (hMSCs) hold the potential for bone regeneration because of their self-renewing and multipotent character. The goal of this study was to evaluate the influence of collagen membranes on the proliferation of hMSCs derived from bone marrow. A special focus was set on short-term eluates derived from collagen membranes, as volatile toxic materials washed out from these membranes may influence cell behavior during the short time course of oral surgery.

Materials and Methods: The proliferation of hMSCs seeded directly on a collagen membrane (BioGide) was evaluated quantitatively using the cell proliferation reagent WST-1 (4-3-[4-iodophenyl]-2-[4-nitrophenyl]-2H-[5-tetrazolio]-1, …

Ada News - 12/09/2013, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

The Effective Dose Of Different Scanning Protocols Using The Sirona Galileos® Comfort Cbct Scanner, David R. Chambers

Electronic Thesis and Dissertation Repository

Introduction: Cone Beam CT imaging is prevalent in dentistry yet much is unknown with regard to how radiation dose to the patient varies between different CBCT scanners and imaging protocols. Scanner and protocol specific effective dose calculations will aid in optimizing individualized protocols for clinical applications.

Purpose: To determine the effective dose for a range of imaging protocols using the Sirona GALILEOS Comfort CBCT scanner.

Materials and Methods: Calibrated InLight nanoDot OSL dosimeters (Landauer, Glenwood, Ill) were placed at 26 select sites in the head and neck of a modified, human tissue-equivalent RANDO phantom. Effective dose was calculated using …

Barriers To Membership In The American Dental Hygienists’ Association In The State Of Georgia, Brandy Henderson

Electronic Theses and Dissertations

Professional associations must have a significant level of membership to be effective. Georgia membership is increasingly low; therefore, ADHA cannot represent dental hygienists’ interests. This study determined factors that caused dental hygienists to continue to forgo membership in the ADHA. Several theoretical views of professional membership were considered. The sample was acquired from an unbiased systematic sampling of 50% (3,270) of registered dental hygienists and a convenience sampling of ADHA nonmembers at 2 continuing education seminars in Georgia. Data collection procedures included an electronic cover letter, consent form, and survey via Survey Monkey or hard copies for seminars. Three hundred …

3-D Oropharyngeal Airway Analysis Of Different Antero-Posterior And Vertical Craniofacial Skeletal Patterns In Children And Adolescents, Chi Kim Huynh

UNLV Theses, Dissertations, Professional Papers, and Capstones

Sleep apnea disorder has recently emerged as a significant public health issue. While the prevalence of obesity is on the rise among children, it is one of the main risk factors associated with apnea. Upper airway dimensions and morphology seem to be major components of obstructive sleep apnea (OSA) and can be affected by different craniofacial patterns. The purpose of this retrospective, cross-sectional pilot study is to correlate gender, Body Mass Index, risk for OSA, neck circumference, and 3-D oropharyngeal airway dimensions in children and adolescents with different antero-posterior (AP) and vertical craniofacial skeletal patterns. A total of 86 pre-orthodontic …

Chhs December 2013 E-Newsletter, Dr. John Bonaguro, Dean, Vashon S. Wells, Editor, College Of Health And Human Services, Western Kentucky University

College of Health & Human Services Publications

No abstract provided.

An Evaluation Of The Quality Assurance Plan At East Tennessee State University’S Dental Hygiene Program, Jennifer E. Fielden

Electronic Theses and Dissertations

Quality assurance in healthcare is fundamental in ensuring the achievement of desired outcomes for patients. In 2011 a quality assurance plan was created at the East Tennessee State University (ETSU) dental hygiene program in order to meet accreditation standards. The purpose of this study was to evaluate this plan in order to determine its effectiveness in improving the quality of patient care indicators. One hundred fifty patient charts were selected and audited. Deficiencies were counted in the categories of assessment, treatment, documentation, referral, caries management, perio management, patient education, and follow-up. Research findings were varied; however, external variables with the …

New Mouthguard Design With Intermediate Nickel-Titanium And Foam Layer, Freddie Martinez

UNLV Theses, Dissertations, Professional Papers, and Capstones

Mouthguards help prevent orofacial injuries in many physical activities, commonly to the maxillary incisors. Mouthguards have many different properties which can be idealized. One property involves the amount of impact force the mouthguard can dissipate, commonly referred to as shock absorption. The aim of this study was to improve shock absorption capabilities beyond the protection that a mouthguard made of Ethylene Vinyl Acetate (EVA) can offer. A Nickel-Titanium (NiTi) and/or foam intermediate layer was placed between EVA. Seven configurations were fabricated at 3 different thicknesses. The configurations consisted of an intermediate layer composed of NiTi, foam, or NiTi/foam. The NiTi …

Sex Determination Using Discriminant Function Analysis In Hispanic Children And Adolescents: A Lateral Cephalometric Study, Alyssa E. Sprowl

UNLV Theses, Dissertations, Professional Papers, and Capstones

Lateral cephalometric radiographs have been used for years to help diagnose skeletal and dental patterns in Orthodontics. Within the last decade, these radiographs have caught the interest of the department of Anthropology for the identification of gender within the adult and adolescent population. Numerous publications have been made but failed to identify sexual dimorphism in the pre-adolescent population. 303 lateral cephalograms of pre and post Latino adolescence age ranging from 6.5 to 17.9 years old were obtained from University of Nevada, Las Vegas (UNLV) digital database. 25 variables were identified and plotted with all linear and angular measurements transferred into …

An Evaluation Of The Frankfort Mandibular Plane Angle Bisector (Fmab) Wits Appraisal In The Assessment Of Anteroposterior Jaw Relationships, Natalie Swoboda

Electronic Thesis and Dissertation Repository

An accurate anteroposterior measurement of jaw relationships is essential in orthodontic diagnosis and treatment planning. The purpose of this longitudinal study was to establish a new cephalometric Wits appraisal using a bisector of the mandibular plane angle, named the Frankfort Mandibular Plane Angle Bisector (FMAB). The FMAB was used to assess the sagittal jaw relationship in a sample of Class I individuals, and compare this measurement to the ANB angle and the Wits appraisal using the Maxillomandibular Bisector (MMB).

The data were collected from pre-treatment (T0), immediate post-treatment (T1) and two year post-retention (T2) lateral cephalograms of 61 male and …

Ada News - 11/18/2013, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Orthodontic Retainers: A Survey Of Patient Compliance And Satisfaction, Bhavana Sawhney

Electronic Thesis and Dissertation Repository

PURPOSE

Retention is an important aspect of orthodontics, which may influence the long-term outcome and satisfaction level of patients who undergo orthodontic treatment. The objective of this study was to identify commonly used orthodontic retainers and retention protocols, and assess patients’ opinions and satisfaction levels with these regimens in relation to several pre-defined variables.

METHODS:

A 149 question survey was created with advanced skip and branching logic. The survey was administered to orthodontic patients at either the one or two year regularly scheduled retention appointment and the overall response rate was 99% (n=131). Data collection included queries on demographics, treatment …

An In-Vitro Study Evaluating The Fracture Resistance And Insertion Torque Of Self-Drilling Mini-Implants Upon Insertion Into Synthetic High Density Mandibular Bone., Angie L. Smith

Electronic Thesis and Dissertation Repository

Introduction: Self-drilling mini-implants are commonly used in orthodontics, but there is little information regarding their fracture resistance in areas of high density bone without pre-drilling.

Purpose: To determine the peak fracture torques of six commonly used self-drilling mini-implants, and to examine how each performs in extreme conditions without pre-drilling.

Materials and Methods: Fifteen mini-implants from six different manufacturers were drilled into acrylic blocks using a custom-made insertion device incorporating a 6-DOF load cell for torque measurements. Peak fracture torques were recorded and compared for each of the six manufacturers. Additionally, ten mini-implants from each manufacturer were inserted into high density …

Ada News - 11/04/2013, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Melorheostosis And Central Giant Cell Granuloma Of The Mandible In A 15-Year-Old Girl, Kenneth M. Anderson, W. H. Shintaku, Molly S. Rosebush, Yeshwant B. Rawal, E. S. Woodard

School of Dentistry Faculty Research and Publications

Melorheostosis is a nonhereditary bone dysplasia primarily affecting the appendicular skeleton. Because clinical and histologic features are often nonspecific, the diagnosis is often based on the radiographic presentation. Involvement of the craniofacial skeleton is rare. We describe a case of a 15-year-old girl with appendicular and craniofacial melorheostosis with adjacent central giant cell granuloma. We discuss the possible significance of this previously unreported finding.

Chhs November 2013 E-Newsletter, Vashon S. Wells, Editor, Dr. John Bonaguro, Dean, College Of Health & Human Services, Western Kentucky University

College of Health & Human Services Publications

No abstract provided.

Predictors Of Dental Care Use: Findings From The National Longitudinal Study Of Adolescent Health, Christopher Okunseri, Elaye Okunseri, Raul I. Garcia, Alexis D. Visotcky, Aniko Szabo

School of Dentistry Faculty Research and Publications

Purpose

To examine longitudinal trends and associated factors in dental service utilization by adolescents progressing to early adulthood in the United States.

Methods

The data source was the National Longitudinal Study of Adolescent Health from Waves I (1994–1995), II (1996), III (2001–2002), and IV (2007–2008). This was a retrospective, observational study of adolescents' transition to early adulthood. We obtained descriptive statistics and performed logistic regression analyses to identify the effects of baseline and concurrent covariates on dental service utilization from adolescence to early adulthood over time.

Results

Dental service utilization within the prior 12 months peaked at age 16 (72%), …

The Effect Of Water Storage On The Bending Properties Of Esthetic, Fiber-Reinforced Composite Orthodontic Archwires, Ju-Han Chang, David W. Berzins, Jessica E. Pruszynski, Richard W. Ballard

School of Dentistry Faculty Research and Publications

Objective: To study the effect of water storage on the bending properties of fiber-reinforced composite archwires and compare it to nickel-titanium (NiTi), stainless steel (SS), and beta-titanium archwires.

Materials and Methods: Align A, B, and C and TorQ A and B composite wires from BioMers Products, 0.014-, 0.016, and 0.018-inch, and 0.019 × 0.025-inch NiTi, 0.016-inch SS, and 0.019 × 0.025-inch beta-titanium archwires were tested (n  =  10/type/size/condition). A 20-mm segment was cut from each end of the archwire; one end was then stored in water at 37°C for 30 days, while the other was stored dry. The segments were …

Ada News - 10/21/2013, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

An Assessment Of Dental Students’ Empathy Levels In Malaysia, Saad A. Khan Dr

Saad A Khan Dr

No abstract provided.

Ada News - 10/07/2013, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Loma Linda University Dentistry - Volume 24, Number 2, Loma Linda University School Of Dentistry, Samah Omar

Articulator (Dentistry Journal)

Contents:

10-13 | Transitions: Goodacre to Dailey
16 | Alumni Student Convention
22 | Resin Infiltration: A Serendipitous Benefit
34 | Commencement 2013: "The Only Times We Have"
39 | Robert Handysides, Associate Dean for Academic Affairs
42 | Pediatric Dentistry Turns Twenty
48 | Dr. Fred Berry Retires

Dental Student Debt In The U.S.: A Mountain To Be Scaled, David G. Dunning

Journal Articles: College of Dentistry

Dental student educational debt in the United States continues to grow as a concern for both dental educators and dental students. While certainly warranted, this concern needs to be understood from the perspective of return on investment. The student debt issue remains a critical one. However, this debt is essentially “good” debt when viewed as an investment made by associates/ employees of general dental practices and general dental practice owners.

Use Of Immersive Visualization For The Control Of Dental Anxiety During Dental Hygiene Treatment, Carmelo Padrino-Barrios

Dental Hygiene Theses & Dissertations

Purpose: The purpose of this study was to determine the effectiveness of immersive visualization (IV) therapy, a technique that provides visual and stereoscopic display through the use of eyewear, in anxious patients during an oral prophylaxis. Methods: A convenience sample of thirty adults was enrolled. A split mouth design was utilized. Subjects were randomly divided into two groups: group A (use of IV for the right side of the mouth), and group B (use of IV for the left side of the mouth). Subjects received a full mouth oral prophylaxis (removal of supra and subgingival calculus and selective polishing), always …

Modulation Of The Effects Of Lung Immune Response On Bone Marrow By Oral Antigen Exposure, Pedro Xavier-Elsas, Cassio Luiz Coutinho Almeida-Da-Silva, L. Pinto, Túlio Queto, Bruno Marques Vieira, M. G. Aramha, Bianca De Luca, Daniela Masid-De-Brito, R. A. Luz, R. S. Lopes, R. Ferreira, Maria Ignez C. Gaspar-Elsas

All Dugoni School of Dentistry Faculty Articles

Allergic airway inflammation is attenuated by oral tolerization (oral exposure to allergen, followed by conventional sensitization and challenge with homologous antigen), which decreases airway allergen challenge-induced eosinophilic infiltration of the lungs and bone marrow eosinophilia. We examined its effects on bone marrow eosinophil and neutrophil production. Mice of wild type (BP-2, BALB/c, and C57BL/6) and mutant strains (lacking iNOS or CD95L) were given ovalbumin (OVA) or water (vehicle) orally and subsequently sensitized and challenged with OVA (OVA/OVA/OVA and H2O/OVA/OVA groups, resp.). Anti-OVA IgG and IgE, bone marrow eosinophil and neutrophil numbers, and eosinophil and neutrophil production ex vivo were evaluated. …

Ada News - 09/16/2013, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.