Open Access. Powered by Scholars. Published by Universities.®
- Discipline
- Keyword
-
- Analysis (5)
- Study (5)
- Adults (4)
- Australian (4)
- Dietary (4)
-
- Health (4)
- Treatment (4)
- After (3)
- Care (3)
- Clinical (3)
- Effects (3)
- Human (3)
- Implications (3)
- Proteins (3)
- South (3)
- Activation (2)
- Automated (2)
- Cells (2)
- Chronology (2)
- Cohort (2)
- Contraceptive (2)
- Development (2)
- Disease (2)
- Efficacy (2)
- Evidence (2)
- Feasibility (2)
- General (2)
- Global (2)
- Group (2)
- Health-related (2)
Articles 331 - 331 of 331
Full-Text Articles in Medicine and Health Sciences
Molecular Evidence Of Synaptic Pathology In The Ca1 Region In Schizophrenia, Natalie Matosin, Francesca Fernandez-Enright, Jeremy Lum, Martin Engel, Jessica L. Andrews, Nils C. Gassen, Klaus V. Wagner, Mathias V. Schmidt, Kelly A. Newell
Molecular Evidence Of Synaptic Pathology In The Ca1 Region In Schizophrenia, Natalie Matosin, Francesca Fernandez-Enright, Jeremy Lum, Martin Engel, Jessica L. Andrews, Nils C. Gassen, Klaus V. Wagner, Mathias V. Schmidt, Kelly A. Newell
Illawarra Health and Medical Research Institute
Alterations of postsynaptic density (PSD)95-complex proteins in schizophrenia ostensibly induce deficits in synaptic plasticity, the molecular process underlying cognitive functions. Although some PSD95-complex proteins have been previously examined in the hippocampus in schizophrenia, the status of other equally important molecules is unclear. This is especially true in the cornu ammonis (CA)1 hippocampal subfield, a region that is critically involved in the pathophysiology of the illness. We thus performed a quantitative immunoblot experiment to examine PSD95 and several of its associated proteins in the CA1 region, using post mortem brain samples derived from schizophrenia subjects with age-, sex-, and post mortem …