Medicine and Health Sciences Commons^™

On The Intrinsic Accuracy And Precision Of The Standardised Growth Curve (Sgc) And Global-Sgc (Gsgc) Methods For Equivalent Dose Determination: A Simulation Study, Jun Peng, Vasilis Pagonis, Bo Li

Faculty of Science, Medicine and Health - Papers: part A

In optically stimulated luminescence (OSL) dating, the single aliquot regenerative-dose (SAR) method has been used extensively for determining equivalent doses (De) in quartz. A variation of the SAR method is the “standardised growth curve” (SGC) method, which has been used as an efficient procedure to save measurement time during dating studies. During the application of the SGC method one establishes the SGC and calculation of the De of an aliquot requires only measurement of the standardised natural dose signal. Recently, a “global standardised growth curve” (gSGC) method was developed as an improved version of the SGC procedure. During the application …

Leveraging Ongoing Research To Evaluate The Health Impacts Of South Africa's Salt Reduction Strategy: A Prospective Nested Cohort Within The Who-Sage Multicountry, Longitudinal Study, Karen E. Charlton, Lisa J. Ware, Elias Menyanu, Richard Berko Biritwum, Nirmala Naidoo, Chine Pieterse, Savathree (Lorna) Madurai, Jeannine Baumgartner, George A. Asare, Elizabeth Thiele, Aletta E. Schutte, Paul Kowal

Faculty of Science, Medicine and Health - Papers: part A

Introduction: Attempting to curb the rising epidemic of hypertension, South Africa implemented legislation in June 2016 mandating maximum sodium levels in a range of manufactured foods that contribute significantly to population salt intake. This natural experiment, comparing two African countries with and without salt legislation, will provide timely information on the impact of legislative approaches addressing the food supply to improve blood pressure in African populations. This article outlines the design of this ongoing prospective nested cohort study. Methods and analysis: Baseline sodium intake was assessed in a nested cohort of the WHO Study on global AGEing and adult health …

A 6-Month Randomised Controlled Trial Investigating Effects Of Mediterranean-Style Diet And Fish Oil Supplementation On Dietary Behaviour Change, Mental And Cardiometabolic Health And Health-Related Quality Of Life In Adults With Depression (Helfimed): Study Protocol, Dorota M. Zarnowiecki, Jihyun Cho, Amy Wilson, Svetlana Bogomolova, Anthony Villani, Catherine Itsiopoulos, Theo Niyonsenga, Kerin O'Dea, Sarah Blunden, Barbara J. Meyer, Leonie Segal, Natalie Parletta

Faculty of Science, Medicine and Health - Papers: part A

Background: Modern diets, characterised by excess consumption of processed foods, are accompanied by an epidemic of chronic diseases. Cardiovascular disease and depression carry a large burden of disease and often occur together. Poor dietary patterns have been identified as an independent risk factor for depression while healthy diets with minimally processed food are protective. Traditional Mediterranean diets have been shown to reduce risk of cardiovascular disease; however there is a need for clinical trials in people with depression. This paper reports the study protocol of a Mediterranean-style diet intervention conducted in adults with self-reported depression. Methods/design: HELFIMED is a parallel …

Development And Feasibility Testing Of Prompt-Care, An Ehealth System For Collection And Use Of Patient-Reported Outcome Measures For Personalized Treatment And Care: A Study Protocol, Afaf Girgis, Geoff P. Delaney, Anthony Arnold, Andrew Alexis Miller, Janelle V. Levesque, Nasreen Kaadan, Martin G. Carolan, Nicole Cook, Kenneth Masters, Thomas T. Tran, Tiffany Sandell, Ivana Durcinoska, Martha Gerges, Sandra Avery, Weng Ng, Stephen Della-Fiorentina, Haryana M. Dhillon, Ashley M. Maher

Illawarra Health and Medical Research Institute

Background: Patient-reported outcome (PRO) measures have been used widely to screen for depression, anxiety, and symptoms in cancer patients. Computer-based applications that collect patients' responses and transfer them to the treating health professional in real time have the potential to improve patient well-being and cancer outcomes.

Objective: This study will test the feasibility and acceptability of a newly developed eHealth system which facilitates PRO data capture from cancer patients, data linkage and retrieval to support clinical decisions and patient self-management, and data retrieval to support ongoing evaluation and innovative research.

Methods: The eHealth system is being developed in consultation with …

Striatal Morphology Correlates With Frontostriatal Electrophysiological Motor Processing In Huntington's Disease: An Image-Hd Study, Lauren Turner, David D. Jakabek, Fiona A. Wilkes, Rodney J. Croft, Andrew Churchyard, Mark Walterfang, Dennis Velakoulis, Jeffrey C. L Looi, Nellie Georgiou-Karistianis, Deborah M. Apthorp

Illawarra Health and Medical Research Institute

Background: Huntington's disease (HD) causes progressive atrophy to the striatum, a critical node in frontostriatal circuitry. Maintenance of motor function is dependent on functional connectivity of these premotor, motor, and dorsolateral frontostriatal circuits, and structural integrity of the striatum itself. We aimed to investigate whether size and shape of the striatum as a measure of frontostriatal circuit structural integrity was correlated with functional frontostriatal electrophysiological neural premotor processing (contingent negative variation, CNV), to better understand motoric structure-function relationships in early HD.

Methods: Magnetic resonance imaging (MRI) scans and electrophysiological (EEG) measures of premotor processing were obtained from a …