Open Access. Powered by Scholars. Published by Universities.®

Medicine and Health Sciences Commons

Open Access. Powered by Scholars. Published by Universities.®

Articles 1 - 5 of 5

Full-Text Articles in Medicine and Health Sciences

A Lipidomic Analysis Of Placenta In Preeclampsia: Evidence For Lipid Storage, Simon H. J Brown, Samuel Eather, Dilys J. Freeman, Barbara J. Meyer, Todd W. Mitchell Jan 2016

A Lipidomic Analysis Of Placenta In Preeclampsia: Evidence For Lipid Storage, Simon H. J Brown, Samuel Eather, Dilys J. Freeman, Barbara J. Meyer, Todd W. Mitchell

Illawarra Health and Medical Research Institute

In preeclampsia, maternal insulin resistance leads to defective expansion of adipocytes, enhanced adipocyte lipolysis, up-regulation of very low density lipoprotein synthesis, maternal hypertriglyceridaemia and the potential for ectopic fat storage. Our aim was to quantitate and compare the total amount and type of lipid in placenta from pregnancies complicated with preeclampsia and healthy pregnancies. Quantitative lipid analysis of lipid extracts from full thickness placental biopsies was carried out by shotgun lipidomics. Placental lipid profiles from pregnancies complicated by preeclampsia (n = 23) were compared to healthy pregnancies (n = 68), and placenta from intrauterine growth restriction pregnancies (n = 10) …


An Automated Chromatography Procedure Optimized For Analysis Of Stable Cu Isotopes From Biological Materials, T. Gabriel Enge, M P. Field, Dianne F. Jolley, Heath Ecroyd, M H. Kim, Anthony Dosseto Jan 2016

An Automated Chromatography Procedure Optimized For Analysis Of Stable Cu Isotopes From Biological Materials, T. Gabriel Enge, M P. Field, Dianne F. Jolley, Heath Ecroyd, M H. Kim, Anthony Dosseto

Illawarra Health and Medical Research Institute

An automated ion-exchange chromatography method is developed for the separation of copper (Cu) from biological samples prior to stable, naturally occurring, isotope analysis. The technique does not require Cu to be fully oxidized/reduced into either Cu+ or Cu2+. Distribution coefficients of Cu and other cations to the Cu-specific anion exchange resin enable the effective purification and separation of Cu from complex matrixes using a single, reusable chromatographic column, with the potential to be modified for varying sample types. The automated chromatography system (prepFAST-MC™) can process up to 60 samples per run at a rate of 36 samples per day on …


Compositional Data Analysis As A Robust Tool To Delineate Hydrochemical Facies Within And Between Gas-Bearing Aquifers, D D.R Owen, V Pawlowsky-Glahn, J J. Egozcue, A Buccianti, John M. Bradd Jan 2016

Compositional Data Analysis As A Robust Tool To Delineate Hydrochemical Facies Within And Between Gas-Bearing Aquifers, D D.R Owen, V Pawlowsky-Glahn, J J. Egozcue, A Buccianti, John M. Bradd

Faculty of Science, Medicine and Health - Papers: part A

Isometric log ratios of proportions of major ions, derived from intuitive sequential binary partitions, are used to characterize hydrochemical variability within and between coal seam gas (CSG) and surrounding aquifers in a number of sedimentary basins in the USA and Australia. These isometric log ratios are the coordinates corresponding to an orthonormal basis in the sample space (the simplex). The characteristic proportions of ions, as described by linear models of isometric log ratios, can be used for a mathematical-descriptive classification of water types. This is a more informative and robust method of describing water types than simply classifying a water …


Many People In Scotland Now Benefit From Anticipatory Care Before They Die: An After Death Analysis And Interviews With General Practitioners, Julia Tapsfield, Charlie Hall, Carey Lunan, Hazel Mccutcheon, Peter Mcloughlin, Joel J. Rhee, Alfonso Leiva, Juliet Spiller, Anne Finucane, Scott Murray Jan 2016

Many People In Scotland Now Benefit From Anticipatory Care Before They Die: An After Death Analysis And Interviews With General Practitioners, Julia Tapsfield, Charlie Hall, Carey Lunan, Hazel Mccutcheon, Peter Mcloughlin, Joel J. Rhee, Alfonso Leiva, Juliet Spiller, Anne Finucane, Scott Murray

Faculty of Science, Medicine and Health - Papers: part A

Background Key Information Summaries (KIS) were introduced throughout Scotland in 2013 so that anticipatory care plans written by general practitioners (GPs) could be routinely shared electronically and updated in real time, between GPs and providers of unscheduled and secondary care. Aims We aimed to describe the current reach of anticipatory and palliative care, and to explore GPs' views on using KIS. Methods We studied the primary care records of all patients who died in 2014 in 9 diverse Lothian practices. We identified if anticipatory or palliative care had been started, and if so how many weeks before death and which …


Can A Clinical Placement Influence Stigma? An Analysis Of Measures Of Social Distance, Lorna Moxham, Ellie K. Taylor, Christopher F. Patterson, Dana J. Perlman, Renee M. Brighton, Susan Liersch, Emily Keough, Tim Heffernan Jan 2016

Can A Clinical Placement Influence Stigma? An Analysis Of Measures Of Social Distance, Lorna Moxham, Ellie K. Taylor, Christopher F. Patterson, Dana J. Perlman, Renee M. Brighton, Susan Liersch, Emily Keough, Tim Heffernan

Faculty of Science, Medicine and Health - Papers: part A

Background The way people who experience mental illness are perceived by health care professionals, which often includes stigmatising attitudes, can have a significant impact on treatment outcomes and on their quality of life. Objective To determine whether stigma towards people with mental illness varied for undergraduate nursing students who attended a non-traditional clinical placement called Recovery Camp compared to students who attended a 'typical' mental health clinical placement. Design Quasi-experimental. Participants Seventy-nine third-year nursing students were surveyed; n = 40 attended Recovery Camp (intervention), n = 39 (comparison group) attended a 'typical' mental health clinical placement. Methods All students completed …