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Full-Text Articles in Medicine and Health Sciences
Intake Of 7,8-Dihydroxyflavone During Juvenile And Adolescent Stages Prevents Onset Of Psychosis In Adult Offspring After Maternal Immune Activation, Mei Han, Ji-Chun Zhang, Wei Yao, Chun Yang, Tamaki Ishima, Qian Ren, Min Ma, Chao Dong, Xu-Feng Huang, Kenji Hashimoto
Intake Of 7,8-Dihydroxyflavone During Juvenile And Adolescent Stages Prevents Onset Of Psychosis In Adult Offspring After Maternal Immune Activation, Mei Han, Ji-Chun Zhang, Wei Yao, Chun Yang, Tamaki Ishima, Qian Ren, Min Ma, Chao Dong, Xu-Feng Huang, Kenji Hashimoto
Illawarra Health and Medical Research Institute
Prenatal infection and subsequent abnormal neurodevelopment of offspring is involved in the etiology of schizophrenia. Brain-derived neurotrophic factor (BDNF) and its high affinity receptor, tropomyosin receptor kinase B (TrkB) signaling plays a key role in the neurodevelopment. Pregnant mice exposed to polyriboinosinic-polyribocytidylic acid [poly(I:C)] causes schizophrenia-like behavioral abnormalities in their offspring at adulthood. Here we found that the juvenile offspring of poly(I:C)-treated mice showed cognitive deficits, as well as reduced BDNF-TrkB signaling in the prefrontal cortex (PFC). Furthermore, the adult offspring of poly(I:C)-treated mice showed cognitive deficits, prepulse inhibition (PPI) deficits, reduced BDNF-TrkB signaling, immunoreactivity of parvalbumin (PV) and peroxisome …
Dietary Iodine Intake Of The Australian Population After Introduction Of A Mandatory Iodine Fortification Programme, Karen E. Charlton, Yasmine Probst, Gabriella Kiene
Dietary Iodine Intake Of The Australian Population After Introduction Of A Mandatory Iodine Fortification Programme, Karen E. Charlton, Yasmine Probst, Gabriella Kiene
Illawarra Health and Medical Research Institute
To address mild iodine deficiency in Australia, a mandatory fortification program of iodised salt in bread was implemented in 2009. This study aimed to determine factors associated with achieving an adequate dietary iodine intake in the Australian population post-fortification, and to assess whether bread consumption patterns affect iodine intake in high-risk groups. Using nationally representative data of repeated 24-h dietary recalls from the 2011-2012 Australian National Nutrition and Physical Activity Survey, dietary iodine intakes and food group contributions were compared by age, socioeconomic status (SES), and geographical remoteness (N = 7735). The association between fortified bread intake and adequacy …
Many People In Scotland Now Benefit From Anticipatory Care Before They Die: An After Death Analysis And Interviews With General Practitioners, Julia Tapsfield, Charlie Hall, Carey Lunan, Hazel Mccutcheon, Peter Mcloughlin, Joel J. Rhee, Alfonso Leiva, Juliet Spiller, Anne Finucane, Scott Murray
Many People In Scotland Now Benefit From Anticipatory Care Before They Die: An After Death Analysis And Interviews With General Practitioners, Julia Tapsfield, Charlie Hall, Carey Lunan, Hazel Mccutcheon, Peter Mcloughlin, Joel J. Rhee, Alfonso Leiva, Juliet Spiller, Anne Finucane, Scott Murray
Faculty of Science, Medicine and Health - Papers: part A
Background Key Information Summaries (KIS) were introduced throughout Scotland in 2013 so that anticipatory care plans written by general practitioners (GPs) could be routinely shared electronically and updated in real time, between GPs and providers of unscheduled and secondary care. Aims We aimed to describe the current reach of anticipatory and palliative care, and to explore GPs' views on using KIS. Methods We studied the primary care records of all patients who died in 2014 in 9 diverse Lothian practices. We identified if anticipatory or palliative care had been started, and if so how many weeks before death and which …