Medicine and Health Sciences Commons^™

Effects Of Microalgae Supplementation On Broiler Meat Quality, Antioxidant Status, And Fatty Acid Profile, Ebrar Filizoğlu, Özlem Karadağoğlu

The Thai Journal of Veterinary Medicine

This study aimed to evaluate the dose-dependent effects of dietary supplementation with Schizochytrium limacinum, a microalga rich in omega-3 fatty acids and bioactive compounds, on the fatty acid composition and antioxidant status of broiler breast meat, as well as its potential effects on growth performance, carcass characteristics, and meat quality. In a 42-day feeding trial, 192 day-old Ross-308 broiler chicks were randomly allocated to four dietary treatment groups (48 chicks per group): a control group fed the basal diet without S. limacinum supplementation (0 g/kg), and three treatment groups fed the basal diet supplemented with 0.25, 0.5, and 1 …

Transcriptomic Profiling Of The Donkey Endometrium Reveals Dynamic Molecular Transitions Across The Estrous Cycle, Limeng Shi, Shuaishuai Wu, Mingyue Zhao, Wenhao Zhou, Abd Ullah, Muhammmad F. Akhtar, Changfa Wang, Muhammad Z. Khan, Ying Han

The Thai Journal of Veterinary Medicine

The endometrium undergoes extensive cyclical remodeling essential for reproductive success; however, the molecular mechanisms governing these processes in donkeys (Equus asinus) remain poorly characterized. To address this gap, we performed high-throughput RNA sequencing on endometrial tissues collected from Dezhou donkeys (n = 16) at four post-ovulation stages: Day 0 (ovulation), Day 3 (early luteal), Day 7 (mid-luteal), and Day 18 (late luteal/pre-luteolysis). Differential gene expression analysis, Gene Ontology enrichment, and KEGG pathway mapping were conducted to characterize temporal transcriptomic dynamics. We identified 2,474, 6,548, and 1,288 differentially expressed genes in Day 0 versus Day 3, Day 0 versus …

Descriptive Anatomy Of The Female Reproductive Organs In Thamin Eld’S Deer (Rucervus Eldii Thamin) And Fea’S Muntjac (Muntiacus Feae) With Utilizing Of The Glycerin Impregnation Technique For Specimen Preservation, Paisan Tienthai, Pawana Chuesiri, Itti Boonorrana, Piyaporn Kongmakee, Ampika Thongphakdee

The Thai Journal of Veterinary Medicine

The reproductive anatomy of rare cervid species remains insufficiently documented, limiting comparative studies and preservation efforts. This study describes the anatomical details in the female reproductive organs of Thamin Eld’s deer (Rucervus eldii thamin) and Fea’s muntjac (Muntiacus feae), while the application of a modified glycerin impregnation technique was achieved for specimen preservation. Dissections of female reproductive tracts revealed morphological variations that correlate with the known female reproductive characteristics of domestic and closely related species. In both species, the ovaries were characterized as small, ovoid structures, exhibiting prominent follicles or corpora lutea consistent with the stage …

Effectiveness Of The Smart Me-De Digital Program On Health Literacy And Glycemic Control In Newly Diagnosed Type 2 Diabetes, Nongnaphat Rungnoei, Siriporn Kruttakart, Natthapan Phianthanyakam, Pakaporn Klinhom, Umaporn Nokpaet, Jintipa Sirikunwiwat, Burong Jaitham

Journal of Health Research

Background: Individuals newly diagnosed with type 2 diabetes often have limited knowledge and self-management skills, leading to poor glycemic control and increased complications. This study evaluated the effectiveness of the Smart ME-DE Digital Program in improving health literacy and glycated hemoglobin levels among newly diagnosed individuals with type 2 diabetes.

Methods: A quasi-experimental study was conducted with seventy participants recruited from diabetes clinics at three hospitals in a central province of Thailand. They were selected using simple random sampling and matched by gender, age, and baseline HbA1c levels, and allocated to an experimental or comparison group. The experimental group received …

Choledochoduodenostomy For The Treatment Of Extrahepatic Bile Duct Carcinoma In A Cat, Qi Zhang, Chunli Han, Anchi Zhang, Zhiying Wan, Yansong Ge, Zheng Wang, Jiasan Zheng

The Thai Journal of Veterinary Medicine

This paper reports a case of feline cholangiocarcinoma, a relatively rare condition in veterinary clinical practice. A 4-year-old female British Shorthair cat was presented with a 10-day history of anorexia and lethargy. An irregularly shaped mass was palpable on abdominal palpation. Diagnostic imaging and serum biochemical findings indicated extrahepatic biliary obstruction, and the diagnosis of cholangiocarcinoma was confirmed by histopathology and immunohistochemistry. Preoperative imaging in this cat indicated that the mass had not invaded major blood vessels such as the portal vein, and no evidence of distant metastasis was detected. The mass was surgically resected, followed by choledochoduodenostomy. The cat …

The Effects Of Jasmine And Champaca Aromatherapy Combined With Acupressure On Sleep Quality In Older Adults With Non-Communicable Diseases: A Quasi-Experimental Study In Rural Northern Thailand, Sriwan Chutithamniti, Katekaew Seangpraw, Prapaporn Tulwattanakul, Manuchet Manotham, Parichat Ong-Artborirak, Nestor Asiamah, Wannita Sakulwattana, Surangkana Chairinkam, Phatcharee Pimalram, Wichida Larsomsri

Journal of Health Research

Background: Poor sleep is common among older adults and negatively affects physical and mental health. This study evaluated the effects of jasmine and champaca essential oil aromatherapy combined with acupressure on sleep quality and cardiovascular parameters among older adults.

Methods: A quasi-experimental study was conducted in rural Phayao, Thailand. Older adults aged ≥60 years with non-communicable diseases and poor sleep quality (Pittsburgh Sleep Quality Index [PSQI] > 5) were assigned to either an intervention group (n = 54), receiving aromatherapy and acupressure for 6 weeks, or a control group (n = 54), receiving usual care. Sleep quality, blood pressure (BP), and …

Factors Influencing Piglet Average Daily Gain During The First Week Of Lactation In Hyperprolific Sow Under Tropical Conditions, Yosua Kristian Adi, Preechaphon Taechamaeteekul, Jakavat Ruampatana, Manmueang Malison, Roy Neville Kirkwood, Padet Tummaruk

The Thai Journal of Veterinary Medicine

Birth weight (BW) is a key determinant of average daily gain (ADG) in piglets; however, hyperprolific sow genetics, particularly under tropical conditions, have increased the proportion of low-birth-weight piglets. This study evaluated factors associated with ADG during the first 7 days of lactation within birth weight categories (1.3 kg). A total of 1,185 piglets from 97 litters that survived to day 7 were included. Factors analyzed were cumulative birth interval, birth order, colostrum intake per kilogram of body weight, rectal temperature at 24 h postpartum, sex, intrauterine growth restriction (IUGR), and cross-fostering. Birth weight, cumulative birth interval, birth order, colostrum …

Depressive Symptoms And Functional Disability Among Older Adults In Nakhon Ratchasima Province, Thailand: A Cross-Sectional Population-Based Study, Jiranya Bureemas, Atthawit Singsalasang

Journal of Health Research

Background: Depressive symptoms have been associated with activities of daily living (ADL) disability; however, evidence among Thai older adults remains limited and inconsistent. This study investigates the association between depressive symptoms and ADL disability in older Thai adults.

Methods: A cross-sectional analytic study was conducted among 312 older adults in Nakhon Ratchasima, Thailand, who were selected using a multistage sampling method. Data were collected between April and July 2023 using structured questionnaires covering demographic and environmental variables. Depressive symptoms were assessed using the 15-item Geriatric Depression Scale. ADL disability was measured using the Barthel and Chula ADL Indices. Multiple logistic …

Impact Of Social Media-Driven Feeding Practices On The Gut Microbiome Of Captive Asian Elephants (Elephas Maximus) In Surin, Thailand, Pongpreecha Malaluang, Nuttapon Bangkaew, Jaruwan Chaiyakhot, Patinya Patikae, Nattaya Watwiengkam, Phimphanit Choklikitumnuey, Thanaphat Phupanna, Sudachanok Phowiset, Prim Chuesaard, Tarid Purisotayo

The Thai Journal of Veterinary Medicine

This study investigated the effects of social media-driven live-streaming dietary supplementation on the gastrointestinal microbial community of captive Asian elephants (Elephas maximus) at the Elephant Kingdom, Surin Province, Thailand. A hierarchical two-tier observational design was used: Tier 1 compared a minimal-supplementation control group (Group H, n = 6) with a frequent heterogeneous-supplementation group (Group L, n = 18); Tier 2 compared, within Group L, low-frequency (Group A, ≤ 3 sessions per week, n = 7) and high-frequency (Group B, > 3 sessions per week, n = 11) live-streaming sub-groups. Faecal microbial profiles were obtained by 16S rRNA gene (V3–V4) …

Molecular Detection Of Chlamydiales In Captive Zoo Animals At Songkhla Zoo, Southern Thailand, Rawikan Inchuai, Sunisa Khongthong, Boontarikaan Wititkornkul, Naruepan Wongpluksin

The Thai Journal of Veterinary Medicine

Several species of Chlamydia are recognized as significant zoonotic pathogens that infect a wide range of hosts, including humans. This study aimed to investigate the occurrence and genetic characteristics of Chlamydiales–related bacteria in captive animals at Songkhla Zoo, southern Thailand. A total of 92 cloacal and rectal swab samples were collected from mammals (n = 22), birds (n = 55), and reptiles (n = 15). Genomic DNA was screened using polymerase chain reaction (PCR) targeting the Chlamydiales 16S rRNA gene and the ompA gene specific for Chlamydia psittaci. Positive amplicons were subjected to Sanger sequencing and phylogenetic analysis. A …

Evaluation Of Diclazuril And Amprolium Against Eimeria Spp. In Vietnamese Broilers: Implications For Intestinal Integrity And Claudin Gene Expression, Nguyen Thi Hoa, Pham Hoang Son Hung, Le Dinh Phung, Le Duc Thao, Nguyen Van Chao, Tran Thi Na, Tran Cao My Linh, Ho Thi Dung

The Thai Journal of Veterinary Medicine

This study aimed to assess the resistance status of Eimeria spp. in Vietnam to diclazuril and amprolium and to evaluate their effects on intestinal recovery following infection. One hundred 12-day-old chicks were randomly allotted to four groups: a non-infected negative control (NC), an infected untreated as positive control (PC), an infected group treated with diclazuril (DI), and an infected group treated with amprolium (AM). At day 14, chicks from all groups except NC were orally challenged with 2 × 10⁴ sporulated Eimeria oocysts (E. tenella, E. maxima, E. acervulina, and E. mitis). On day 7 …

The Role Of The Nlrp3 Inflammasome In Preeclampsia And Implantation Failure: A Molecular Review, Ari Budi Suryawinata, Mariel Tania Darmayani, Listyani Suhargo

Chulalongkorn Medical Journal

The NOD-like receptor family pyrin domain containing 3 (NLRP3) inflammasome is a critical multiprotein complex of the innate immune system that functions as a molecular sensor for a wide array of danger signals. While its activation is essential for host defense and tissue homeostasis, its dysregulation is increasingly implicated in the pathophysiology of numerous inflammatory disorders. This review article synthesizes the current molecular understanding of the NLRP3 inflammasome, focusing on its dual role in health and disease. We first provide a concise overview of the canonical two-step mechanism of NLRP3 activation and the intricate molecular checkpoints including genetic factors, post-translational …

Effects Of Maternal Vitamin D Supplementation During Pregnancy And Lactation On Immune Development In Offspring: A Systematic Review, Kurnia Maidarmi Handayani, Ghaniyyatul Khudri, Laura Zeffira, Widia Sari

Chulalongkorn Medical Journal

Background: Vitamin D, a fat-soluble prohormone, is essential for skeletal health and plays a key role in immune regulation. Deficiency is common among pregnant and lactating women, raising concerns as fetal and neonatal vitamin D status relies entirely on maternal stores. Insufficiency during these periods is linked to preterm birth, low birth weight, and immune-mediated disorders. This review examines the effects of maternal vitamin D supplementation on the immune development of offspring.

Methods: A systematic review was conducted in accordance with PRISMA guidelines and registered in PROSPERO (CRD420251117397). Experimental rodent studies published between 2019 and 2022 that investigated maternal vitamin …

Skip Segment Hirschsprung's Disease: Report Of A Rare Case And Literature Review, Nimmita Srisan, Paisarn Vejchapipat, Natcha Wanpiyarat

Chulalongkorn Medical Journal

We present an unusual case of skip segment Hirschsprung’s disease which was initially diagnosed with total colonic aganglionosis. A term male newborn presented with distal intestinal obstruction underwent exploratory laparotomy at three days old after ultrasound-guided contrast enema. Intra-operative frozen section of the full-thickness biopsies of each part of the colon and terminal ileum reported no ganglion cells, so we performed double-end ileostomy. Although all the final pathology reports confirmed no ganglion cells similar to the frozen sections, we were curious about the problematic bowel because of preoperative imaging (at the age of 30 months) which showed dilated transverse colon. …

Pituitary Apoplexy In A 19-Year-Old Woman: An Uncommon Age And Gender Presentation, I Ketut Aryawan, Jovita Jutamulia

Chulalongkorn Medical Journal

Pituitary apoplexy is a rare clinical syndrome caused by acute hemorrhage or infarction of the pituitary gland. It is most frequently reported in men during the 5th and 6th decades of life and is rarely encountered in young women. We describe a 19-year-old woman who presented with acute visual disturbance accompanied by occasional mild headache. Ophthalmologic examination revealed bitemporal hemianopia, and head MRI demonstrated an intrasellar mass with suprasellar extension, intratumoral hemorrhage, and optic chiasm compression, consistent with pituitary macroadenoma with apoplexy. The patient also had a history of secondary amenorrhea, suggesting possible endocrine dysfunction. This case highlights the importance …

Association Between Underpants Fit And Semen Quality: A Hospital-Based Cross-Sectional Study, Harnam Kaur, Unnop Jaisamrarn, Paweena Thuwanut, Chanakarn Suebthawinkul, Jiayu Li

Chulalongkorn Medical Journal

Background: The effect of underpants type on semen parameters remains controversial. Conducting such a study in the Thai population will contribute valuable region-specific data.

Objectives: This cross-sectional research studied the influence of fit of underpants worn on various semen parameters including semen volume, sperm count, sperm motility, sperm morphology and sperm DNA fragmentation among Thai male partners in Bangkok, Thailand.

Methods: Thai male partners aged 20–55 years who sought infertility treatment from Reproductive Biology Unit, King Chulalongkorn Memorial Hospital, Bangkok were recruited from March to June 2024. All participants completed questionnaire covering socio-demographics, disease history, and type of underpants worn …

Effectiveness And Implementation Of The Shield Integrated Multi-Level Model To Reduce Adolescent Depression And Internet Addiction: A Cluster Randomized Waitlist-Controlled Trial In Wangchin District, Phrae Province, Seubtrakul Tantalanukul, Amornpan Samorn

Chulalongkorn Medical Journal

Background: Adolescent depression and internet addiction represent significant comorbid mental health challenges in rural Thailand, where access to evidence-based interventions remains limited. Traditional single-modality approaches often fail to address the complex interplay between individual, family, and systemic factors contributing to these conditions.

Objectives: To evaluate the effectiveness and implementation outcomes of the SHIELD (Screening & Surveillance, Health Literacy Enhancement, Internet Wellness Program, Empowering Families, Linkage to Care, Data-driven Monitoring) integrated multi-level intervention for reducing depression and internet addiction among at-risk adolescents in rural Thailand.

Methods: A cluster randomized waitlist-controlled trial was conducted across eight secondary schools in Wangchin District, Phrae …

Computed Tomography Findings Of Normal Appendix In Pediatric Population, Thanwarat Koonthong, Teerasak Phewplung*

Chulalongkorn Medical Journal

Background: Appendicitis remains the most common indication for emergency abdominal surgery in children. Computed tomography (CT) plays a vital role in the evaluation of pediatric patients with suspected appendicitis. Yet, there is limited of literature describing the normal appendiceal diameter in the pediatric Asian population.

Objectives: To characterize the normal pediatric appendix and to identify the variables that influence its diameter in pediatric patients aged one day to 18 years who underwent abdominal CT.

Materials and Methods: The study was approved by the IRB. We conducted a retrospective study of 358 children (≤18 years of age) who underwent abdominal CT …

Global Trends In School Disaster Preparedness Research: Bibliometric Analysis Impacts On Public Health And Safety, Muhammad Farid, Muhammad Agita Hutomo, Oktomi Wijaya, Dian Ika Puspitasari

Chulalongkorn Medical Journal

Background: Disasters disrupt daily human activities, arising from natural or artificial triggers, with varying impacts based on community vulnerability and resource capacity. Effective disaster management involves a cycle of mitigation, preparedness, response, and recovery. One of the mitigation measures is to establish school disaster preparedness that integrate education and capacity building.

Objective: The aim of this research is to conduct a bibliometric analysis based on Scopus publications regarding school disaster preparedness.

Methods: A bibliometric analysis was performed on publications indexed in Scopus from 1965 to 2024. Data were processed and visualized using VOSviewer to explore trends in annual outputs, contributing …

Serial Radiographic And Ultrasonographic Evaluation Of Discospondylitis In A Cat: A Case Report Of Progressive Vertebral Lysis Despite Clinical Improvement, Geunah Kim, Jungho Lee, Seulgi Bae, Sang-Kwon Lee, Kija Lee

The Thai Journal of Veterinary Medicine

A 10-year-old castrated male Korean Shorthair cat was presented with a 5-day history of lethargy and nonambulatory paraparesis. Neurological examination revealed delayed postural reactions in both pelvic limbs. Initial radiography of the lumbar spine revealed narrowing of the L7–S1 intervertebral disc space with ventral bony proliferation. Magnetic resonance imaging revealed collapse of the L7–S1 intervertebral disc space with heterogeneous T2-weighted hyperintensity and ventral contrast enhancement of the affected disc, as well as contrast enhancement of the adjacent paraspinal musculature. These findings suggested the presence of discospondylitis. Coccoid bacteria detected in both urine and splenic fine-needle aspirate indicated hematogenous spread. The …

Prevalence And Genotypes Of Enterocytozoon Bieneusi In Captive Wild Hedgehogs (Erinaceus Amurensis) In China, Guo-Liang Chen, Yu-Lin Zhou, Xin Liu, Ming Shu, Can Yin

The Thai Journal of Veterinary Medicine

Enterocytozoon bieneusi is now recognised as an emerging pathogen, which can cause a series of intestinal diseases in humans and animals. However, limited information is available about the occurrence of E. bieneusi in hedgehogs. In this study, a total of 205 fecal samples of captive wild hedgehogs (Erinaceus amurensis) were collected from two wildlife conservation centers in Henan and Anhui provinces, China. Genomic DNA was extracted from the stool samples and screened by nested PCR targeting the internal transcribed spacer (ITS) sequences. The overall prevalence of E. bieneusi in captive wild hedgehogs was 44.4% (91/205). Five zoonotic genotypes were identified, …

Reference Values For Intraocular Pressure In Collared Scops Owls (Otus Lettia) Measured Using Rebound Tonometry, Yun-Shan Chiu, Chau-Hwa Chie, Pin-Huan Yu, Chung-Tien Lin

The Thai Journal of Veterinary Medicine

In this study, we aimed to establish species-specific reference values for intraocular pressure (IOP) in clinically healthy collared scops owls (Otus lettia) using rebound tonometry. Twelve free-living owls were included, and twentyfour eyes were examined. All owls were physically restrained in an upright position without sedation. Intraocular pressure was measured in both eyes using rebound tonometry (TONOVET; iCare Finland Oy, Vantaa, Finland) in d mode. No significant difference in IOP was observed between the right and left eyes. The mean IOP values were 10.42 ± 1.24 mmHg (median, 11 mmHg; range, 8–12 mmHg) in the right eye and 10.75 ± …

Strategies For Improving The Drug Importation Control System In Thailand: A Qualitative Investigation, Neeranart Potiyanon, Suntaree Watcharadamrongkun

The Thai Journal of Pharmaceutical Sciences

Background: Drug importation plays a critical role in Thailand’s healthcare system; however, barriers affecting its regulatory control and their public health implications remain inadequately examined. This study compared international drug importation procedures and evaluated Thailand’s control system with strategies for improvement.
Methods: Conducted in Bangkok between 2020 and 2023, this two-phase study employed a qualitative design. Phase 1 involved content analysis comparing drug importation procedures across Thailand, Singapore, Australia and the United States to identify best practices and potential solutions. Phase 2 utilized semistructured, in-depth interviews with 19 key informants from government and private-sector agencies. Data collection was guided by …

Artificial Intelligence In Hospital Pharmacy Practice: Effectiveness, Internal Validity, And Translational Readiness: A Systematic Review, Kwanchai Rattanamanee, Parnupong Kiewsiri, Prayuth Poowaruttanawiwit

The Thai Journal of Pharmaceutical Sciences

Background: Artificial intelligence (AI) is increasingly integrated into hospital pharmacy, offering potential to enhance medication safety, therapeutic decision-making, and operational efficiency. However, the internal validity and translational readiness of current interventions remain uncertain.
Objectives: The objective of the study was to systematically review AI applications in hospital pharmacy and evaluate their effectiveness, internal validity, and readiness for clinical integration.
Methods: Following Preferred Reporting Items for Systematic reviews and Meta-Analyses 2020 guidelines and PROSPERO registration (CRD420251067936), We systematically searched PubMed, Embase, Scopus, Web of Science, IEEE Xplore, and ThaiJO (2000–June 2025). for randomized controlled trials (RCTs), cohort, quasi-experimental, and case–control studies …

Assortment Analysis Of Ophthalmic Medicines In The Republic Of Uzbekistan, Zoya Usmonova, Shakhnoz Umarova, Nargiza Sultanbaeva, Marina Taryanikova

The Thai Journal of Pharmaceutical Sciences

Background: Ophthalmic diseases are a significant public health concern globally and in Uzbekistan, where approximately 1 million individuals are affected.
Objectives: The objectives are to conduct an assortment analysis of ophthalmic medicines registered in Uzbekistan (2010–2024), to identify trends in drug registration, composition, dosage forms, and manufacturing sources.
Materials and Methods: Based on State Register data, medicines classified under Anatomical Therapeutic Chemical S01 were analyzed using marketing and qualimetric methods, focusing on the International Nonproprietary Names, dosage forms, manufacturers, and countries of origin.
Results: The number of registered medicines peaked at 352 in 2022, and then declined to 279 in …

Contribution Of Animals To Biomedical Advancements In The Current Era: A Narrative Review, Leena Rajathy Port Louis, Mani Rajarathinam, Prithiviraj Nagarajan, Divya Sekar, Nisha Perumal

The Thai Journal of Pharmaceutical Sciences

Animal research has played a major role in the development of vaccinations and therapies for illnesses such as tetanus, polio, meningitis, hepatitis, and Severe Acute Respiratory Syndrome Coronavirus 2. For every prescription drug available today, animal testing and research have contributed immensely. This narrative review aims to explore the contribution of animals to biomedical advancements in the current era, which involved a search of peer-reviewed literature using electronic databases such as Scopus, Web of Science, and PubMed. In current biomedical research, animals help develop new treatments for long-term illnesses such as cancer, HIV, and Alzheimer’s. Animals also aid in the …

Microwave-Assisted Extraction Optimization And Bioactivity Assessment Of Flavonoid-Rich Extract From Lantana Camara L. Leaves In Zebrafish Epilepsy Model, Prem Kumar B R, Shwetha Krishnamurthy, Gouri Nair, Sundara Saravanan Kamatchi

The Thai Journal of Pharmaceutical Sciences

Background: Lantana camara L. (Verbanaceae) is known for its bioactive compounds and has been reported for its potential therapeutic applications. Flavonoids from natural sources are acknowledged for their antioxidant and neuroprotective properties, suggesting a possible role in seizure management.
Objectives: This study intended to optimize the microwaveassisted extraction (MAE) of flavonoid-rich extract from L. camara L. leaves utilizing a designof- experiment approach and evaluate its antiepileptic property using the zebrafish model.
Materials and Methods: Four solvents (ethyl acetate, acetone, ethanol, and water) were initially used, with ethanol yielding the highest total flavonoid content (TFC). A central composite design was employed …

Samannachan: A Thai Traditional Herbal Recipe With Cytotoxic Potential Against Breast, Cervical, And Ovarian Cancers, Perika Monkanna, Srisopa Ruangnoo, Pakakrong Thongdeeying, Arunporn Itharat, Pranporn Kuropakornpong, Reawfang Sriyom, Apinya Wiboonwattanakit, Kanyarat Namphonsan, Paponpachara Pibanpaknitee, Neal M. Davies

The Thai Journal of Pharmaceutical Sciences

Background: Samannachan (SMC) is a Thai traditional herbal recipe that has been used since 2005 at Khampramong Temple, Sakon Nakhon, to treat more than 6,000 cancer patients. However, scientific evidence supporting cytotoxic effects remains limited.
Objectives: The objective of the study is to evaluate the cytotoxicity of the SMC recipe and its ten herbal components against breast, cervical, and ovarian cancer cells compared to normal cells.
Methods: Cytotoxic activity was assessed using the sulforhodamine B (SRB) assay on breast (MCF-7, T47D, MDA-MB-231), cervical (HeLa), and ovarian (SK-OV-3) cancer cell lines, as well as on non-cancerous human keratinocytes (HaCaT). Both aqueous …

Hypovitaminosis A - Associated Neurologic Syndrome With Concurrent Babesiosis In A Captive African Lion Cub (Panthera Leo), Kano, Nigeria, Shaarani Habibu Musa, Aminu Bello Hanga, Auwal Usman Nagoma, Caleb Ayuba Kudi, Paul Ayuba Abdu, Musa Ibrahim Waziri, Haruna Baba Galadima, Yusuf Aminu Yusuf, Muhammed Mikail

The Thai Journal of Veterinary Medicine

Neurological disorders in captive wild felids presents diagnostic and therapeutic challenges, particularly in juveniles animals maintained under suboptimal nutritional transitions. This case report describes the synergistic effects of dietary deficiencies and a concurrent hemoparasitic infection in a seven-month-old male African lion cub (Panthera leo) weighing 30 kg, housed at Audu Bako Zoological Garden in Kano, Nigeria. Following premature weaning onto an unsupplemented muscle-meat diet, the cub exhibited progressive neurological symptoms, including ataxia, hindlimb paresis, star-gazing, and opisthotonos. Hematological analysis revealed a mild normocytic, normochromic anemia (packed cell volume; 23%) and the presence of erythrocytes rouleaux formation, while Giemsa-stained …

Effects Of Acepromazine On Intraocular Pressure, Anterior Chamber Depth In Horses: A Prospective Randomized Controlled Study, Abdelhaleem Elkasapy, Magdy Elgioushy, Mohamed Marzok, Sayed Elhawari, Adel Almubarak, Mohamed Rizk, Sabry El-Khodery, Adel Al-Akraa

The Thai Journal of Veterinary Medicine

This study aimed to evaluate the effects of acepromazine on intraocular pressure (IOP), anterior chamber depth (ACD), cardiovascular and respiratory rates in horses. In a prospective, randomized, controlled trial, twelve horses were equally allocated randomly into two groups: treatment and control (n = 6 each). Horses of the treatment group received 0.1 mg/kg body weight (bwt) of acepromazine intravenously, while those in the control group received 0.4 mL/100 kg bwt of 0.9% sodium chloride intravenously. IOP, ACD, heart rate, and respiratory rate were recorded before (T0) and then at T10, T20, T30, T40, T50, T60, T70, T80, and T120 min …