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Articles 181 - 210 of 11369

Full-Text Articles in Medicine and Health Sciences

Combined Anterior Palatoplasty With Barbed Suspension Pharyngoplasty In The Treatment Of Obstructive Sleep Apnea, Patheemon Thanachaikun, Natamon Charakorn Jun 2025

Combined Anterior Palatoplasty With Barbed Suspension Pharyngoplasty In The Treatment Of Obstructive Sleep Apnea, Patheemon Thanachaikun, Natamon Charakorn

Chulalongkorn Medical Journal

Background: Surgery is a treatment option for obstructive sleep apnea (OSA) patients for whom positive airway pressure therapy is not chosen. Various palatal surgical techniques have been developed. However, the medical literature has limited accounts concerning the use of combination of these techniques to improved outcomes.

Objective: The aim of this study is to assess the efficacy of a combined anterior palatoplasty (AP) and barbed suspension pharyngoplasty (BSP) in treating adult OSA.

Methods: Data of OSA patients who underwent the combined AP with BSP between July 2020 to May 2024 were retrospectively reviewed. The surgical outcomes, including apnea-hypopnea index (AHI), …


The Factors Affecting The Distribution Of Scorpions (Arachnida: Scorpions) In Iran, Hassan Nasirian Jun 2025

The Factors Affecting The Distribution Of Scorpions (Arachnida: Scorpions) In Iran, Hassan Nasirian

Chulalongkorn Medical Journal

Background: The distribution of scorpions is influenced by various factors that determine their presence and abundance in different regions. Understanding these factors is crucial for comprehending scorpion ecology and predicting their potential impact on ecosystems. Objective: These subtopics aim to provide an overview of the distribution of scorpions within Iran and the factors affecting their distribution, highlighting their ecological preferences and adaptations to different regions.

Methods: Forty-nine documents were collected from well-known indexing services, including Elsevier, Google Scholar, PubMed, ScienceDirect, Scopus, Springer, and Web of Science. After carefully studying the documents, they were classified into specific topics and discussed.

Results: …


Job Strain And Associated Factors Among Medical School Employees In Thailand: A Cross-Sectional Study, Jakarin Apisuttisin, Pornchai Sithisarankul, Jate Ratanachina Jun 2025

Job Strain And Associated Factors Among Medical School Employees In Thailand: A Cross-Sectional Study, Jakarin Apisuttisin, Pornchai Sithisarankul, Jate Ratanachina

Chulalongkorn Medical Journal

Introduction: Mental health issues are rising among workers, often linked to job strain. Medical schools, with their diverse workforce including not only healthcare workers and educators but also support staff, are in demanding work environments and are susceptible to job strain. This study aimed to investigate the prevalence and associated factors of job strain among support staff at a medical school in Bangkok, Thailand.

Methods: A cross-sectional study of 721 support staff employed at a medical school in Bangkok, Thailand was conducted between May and July 2024. The questionnaire consisted of three sections including demographic data, work-related factors, and the …


Clinical Factors Predicting The Need For Biopsy In Children With Cervical Lymphadenopathy, Pornchai Achatsachat, Nimmita Srisan, Prapapan Rajatapiti, Katawaetee Decharun, Somboon Reukvibunsi, Paisarn Vejchapipat Jun 2025

Clinical Factors Predicting The Need For Biopsy In Children With Cervical Lymphadenopathy, Pornchai Achatsachat, Nimmita Srisan, Prapapan Rajatapiti, Katawaetee Decharun, Somboon Reukvibunsi, Paisarn Vejchapipat

Chulalongkorn Medical Journal

Background: Lymphadenopathy in children is often a diagnostic challenge for clinicians. It may be one symptom of many diseases including granulomatous diseases and malignancy. The cervical region is a commonly involved area in peripheral lymphadenopathy. Surgical biopsy often provides a definitive diagnosis but occasionally unnecessary in some cases.

Objectives: The objective was to describe children with cervical lymphadenopathy who underwent surgical biopsies and to determine clinical factors that can predict the likelihood of lymph nodes needing further management (LNFM) including granulomatous and malignant lymph nodes. Methods: Data of 87 children with cervical lymphadenopathy undergoing surgical biopsy were retrospectively reviewed. Descriptive …


Psychometric Evaluation Of The Thai Version Of Emotional Labor Scale (T-Els) In Thai Nurses, Vachira Posai, Wisarut Srisintorn, Paramee Thongsuksai, Chanokporn Jitpanya Jun 2025

Psychometric Evaluation Of The Thai Version Of Emotional Labor Scale (T-Els) In Thai Nurses, Vachira Posai, Wisarut Srisintorn, Paramee Thongsuksai, Chanokporn Jitpanya

Journal of Health Research

Background: Nurses often face emotional strain due to emotional labor (EL), which involves concealing or modifying genuine feelings to meet their job requirements. This response can lead to physical, psychological, and behavioral issues. The Emotional Labor Scale (ELS), originally in English, has not been translated into Thai, leaving its psychometric properties unexamined in the Thai context. This study aimed to translate the ELS into Thai and evaluate its psychometric properties among Thai nurses.

Methods: A cross-sectional study design was used. The 14-item scale, which includes surface acting, deep acting, and expression of naturally felt emotions dimensions, was translated using forward …


Predictive Model For Hemoglobin Levels Using Multiple Linear Regression, Dien Gusta Anggraini Nursal, Muhammad Daffa Atthariq Winata, Nohan Arum Romadlona, Noura Rizki, Sabillah Nasitoh, Muhammad Sakhi Baretta Jun 2025

Predictive Model For Hemoglobin Levels Using Multiple Linear Regression, Dien Gusta Anggraini Nursal, Muhammad Daffa Atthariq Winata, Nohan Arum Romadlona, Noura Rizki, Sabillah Nasitoh, Muhammad Sakhi Baretta

Journal of Health Research

Background: Anemia is a condition in which the number of red blood cells or hemoglobin (Hb) levels fall below normal, limiting the ability of blood to transport oxygen effectively. This study aimed to develop a predictive model for Hb levels by identifying significant risk factors.

Method: This observational analytic study was conducted among 103 randomly selected students of Bung Hatta University in Padang, Indonesia. Data were collected with a questionnaire and a hemoglobin test between April to May 2024. Pearson’s correlation analysis and multiple linear regression were performed in this study.

Results: Bivariate analysis showed significant correlations between Hb levels …


Effect Of Post-Operative Clothing, Bandage, And Collar Application On Stress After Ovariohysterectomy In Cats, Çağatay Esin, Seba Raouf, Gülşah Saral, Büşra Uzun Jun 2025

Effect Of Post-Operative Clothing, Bandage, And Collar Application On Stress After Ovariohysterectomy In Cats, Çağatay Esin, Seba Raouf, Gülşah Saral, Büşra Uzun

The Thai Journal of Veterinary Medicine

Ovariohysterectomy is a common surgical procedure in veterinary medicine, not only for reproductive control but also for conditions like pyometra, metritis, mammary tumors, and other reproductive disorders. Pain in cats occurs as a response of the body and is accompanied by various physiological and behavioral changes. Pain in cats, though prevalent, is often under-recognized and inadequately treated. The Glasgow pain scale is a psychometrically designed tool for assessing acute pain in veterinary patients. Serotonin (5-HT), a biogenic monoamine derived from tryptophan, functions as a mood-regulating neurotransmitter and may decrease following surgical interventions. This study aimed to evaluate post-operative pain and …


Assessing The Efficacy Of Eutectic Mixture Of Local Anesthesia Cream And Vapocoolant Spray In Mitigating The Pain Associated With Ear-Tagging In Pre-Weaned Calves, Yu-Jhe Lo, Thomas Chia-Tang Ho, Jacky Peng-Wen Chan Jun 2025

Assessing The Efficacy Of Eutectic Mixture Of Local Anesthesia Cream And Vapocoolant Spray In Mitigating The Pain Associated With Ear-Tagging In Pre-Weaned Calves, Yu-Jhe Lo, Thomas Chia-Tang Ho, Jacky Peng-Wen Chan

The Thai Journal of Veterinary Medicine

This study evaluated the efficacy of a eutectic mixture of local anesthetics (EMLA) cream and vapocoolant spray (VS) in preventing pain in calves following ear-tagging. Thirty-four calves were randomly assigned to three groups: no anesthesia control (CON, n=11), EMLA applied 60 minutes prior (EMLA, n=11), and five-second VS application immediately prior (VS, n=12). Pain pressure threshold (PPT) was measured at 18±1 days of age, with the left ear of the CON group serving as the sham group (Sham, n=11), followed by ear-tagging at 21±1 days. Post-tagging assessments included pain-related behaviors, serum cortisol levels, heart rate, and wound scores. The PPT …


Ultrasound-Guided Sciatic And Femoral Nerve Block For Perioperative Pain Management In A Thai Crossbreed Dog Undergoing Tibial Plateau Leveling Osteotomy (Tplo): A Case Report, Wutti Bunjerdsuwan, Sirirat Niyom May 2025

Ultrasound-Guided Sciatic And Femoral Nerve Block For Perioperative Pain Management In A Thai Crossbreed Dog Undergoing Tibial Plateau Leveling Osteotomy (Tplo): A Case Report, Wutti Bunjerdsuwan, Sirirat Niyom

The Thai Journal of Veterinary Medicine

This case report presents the use of ultrasound-guided sciatic and femoral nerve blocks as an alternative analgesic technique for perioperative pain control in a Thai crossbreed dog undergoing left tibial plateau leveling osteotomy (TPLO). The orthopedic examination revealed a 4/5 left hindlimb lameness score, with positive results on both the tibial compression test (TCT) and cranial drawer test (CDT). Radiographic evaluation showed the absence of a fat pad sign and osteophyte formation around the left stifle joint. A definitive diagnosis of left cranial cruciate ligament rupture (CCLR) was made. The dog underwent CCLR correction via TPLO, with perioperative pain managed …


Fall Incidences, Risk Factors, And Health Effects Among Early- And Middle-Aged Elderly People In Rural Areas Of Border Provinces In Southern Thailand, Phnom Sukchan, Tapanan Prateepko, Arinda Ma-A-Lee, Kruawan Hounkong, Penporn Sujiwattanarat, Gornganok Piboonpol May 2025

Fall Incidences, Risk Factors, And Health Effects Among Early- And Middle-Aged Elderly People In Rural Areas Of Border Provinces In Southern Thailand, Phnom Sukchan, Tapanan Prateepko, Arinda Ma-A-Lee, Kruawan Hounkong, Penporn Sujiwattanarat, Gornganok Piboonpol

Journal of Health Research

Background: Elderly individuals with physical and psychological challenges face a high risk of falls. This study aimed to assess the incidence, health effects of, and risk factors for falls among those aged 60-79 years old in Thailand's three southern border provinces.

Methods: A community cross-sectional study was conducted between October 2021 and September 2022. Questionnaires were administered though verbal face-to-face conversations. Descriptive statistics, the Chi-square test, Fisher’s exact test, and logistic regression were used.

Results: A total of 419 elderly participants were recruited, while 374 participated in the study. The incidence of falls was 37.4% with an average of 1.7 …


Diagnostic Imaging Of A Large Pancreatic Pseudocyst With Infection Over Time In A Dog, Chanyoung Ryu, Wooseok Jin, Sang-Kwon Lee, Daji Noh, Sooyoung Choi, Kija Lee May 2025

Diagnostic Imaging Of A Large Pancreatic Pseudocyst With Infection Over Time In A Dog, Chanyoung Ryu, Wooseok Jin, Sang-Kwon Lee, Daji Noh, Sooyoung Choi, Kija Lee

The Thai Journal of Veterinary Medicine

A 5-year-old Pompitz presented with anorexia and vomiting. Radiographs showed a half-moon-shaped mass in the left cranial abdomen. A large cyst was identified near the left pancreas on ultrasound. Computed tomography revealed a fluid-attenuating mass with rim enhancement in the pancreas. Laboratory tests identified Staphylococcus warneri in the cystic lesion, and pancreatic pseudocyst with infection was suspected. The fluid accumulation and clinical signs recurred over several months. Pre-operative magnetic resonance imaging showed a hyperintense cystic lesion with a duct-like structure and hyperintense line between the cyst and the gastric wall on T2-weighted images as well as signal change of the …


Assessment Of The Relationship Between Particulate Matter Level And Respiratory Diseases In Dogs And Cats In Bangkok, Thailand, Nattawan Tangmahakul, Janenisa Klomklao, Damisa Thanyapornsombat, Tuangphon Lertsubkhajohn, Wiphawa Piboonlapudom, Satraporn Mettaviparee, Sirilak Disatian Surachetpong Apr 2025

Assessment Of The Relationship Between Particulate Matter Level And Respiratory Diseases In Dogs And Cats In Bangkok, Thailand, Nattawan Tangmahakul, Janenisa Klomklao, Damisa Thanyapornsombat, Tuangphon Lertsubkhajohn, Wiphawa Piboonlapudom, Satraporn Mettaviparee, Sirilak Disatian Surachetpong

The Thai Journal of Veterinary Medicine

Particulate matter (PM) 2.5 has become a serious pollution concern in many countries, including Thailand. Due to its small particle size, PM2.5 can penetrate deep into pulmonary tissues, posing health risks to humans. Furthermore, it is hypothesized that PM2.5 may also cause respiratory diseases in dogs and cats. This study aimed to evaluate a relationship between PM2.5 levels and the number of dogs and cats visiting due to respiratory problems in Bangkok, Thailand, and to investigate potential environmental factors that may contribute to these health outcomes. A total of 184 dogs and 73 cats were included in the study. Medical …


Impact Of Colostrum Lactose Concentration In Relation To Metabolomic Profiles On Kid Growth Performance Of Black Bengal Goats, Tien Thi Phuong Vo, Chollada Buranakarl, Sumonwan Chamsuwan, Sumpun Thammacharoen, Morakot Nuntapaitoon, Sarn Settachaimongkon Apr 2025

Impact Of Colostrum Lactose Concentration In Relation To Metabolomic Profiles On Kid Growth Performance Of Black Bengal Goats, Tien Thi Phuong Vo, Chollada Buranakarl, Sumonwan Chamsuwan, Sumpun Thammacharoen, Morakot Nuntapaitoon, Sarn Settachaimongkon

The Thai Journal of Veterinary Medicine

Colostrum composition, including lactose concentration in relation to metabolomic profiles on kids’ growth performance of Black Bengal goats, has not yet been elucidated. Macronutrients, including lactose and metabolomic profiles, were determined in 37 colostrum samples using MilkoScan and 1H-nuclear magnetic resonance technique, respectively. Kids’ growth performance, including birth weight, average daily gain at 0–4 weeks (ADG0-4W), 4–8 weeks (ADG4-8W), and wean weight were determined. A total of 51 metabolites were detected in the colostrum. From the general linear model for univariate analysis, kids born from multiple litter sizes showed lower ADG during the first month postpartum (P = 0.004). …


Safety Study Of Polyunsaturated Fatty Acids Extracted From New Zealand Green Lipped Mussel And Krill On Hematology And Blood Chemistry Profiles Of Healthy Dogs And Cats, Uttra Jamikorn, Panumas Kongpanna Apr 2025

Safety Study Of Polyunsaturated Fatty Acids Extracted From New Zealand Green Lipped Mussel And Krill On Hematology And Blood Chemistry Profiles Of Healthy Dogs And Cats, Uttra Jamikorn, Panumas Kongpanna

The Thai Journal of Veterinary Medicine

New Zealand green-lipped mussel (Perna canaliculus) is a shellfish with a green shell containing many types of fatty acids, especially polyunsaturated fatty acids (PUFAs). The aim of the present study was to investigate the safety of dietary PUFAs supplementation on blood hematology, chemistry and coagulogram pancreatic enzymes in dogs and cats. Twelve healthy beagle dogs and healthy mature cats were used in these studies. Complete randomized block and triplicate 4×4 Latin square designs were used for these dog and cat safety studies, respectively. Experimental diets composed of sham control (0X) and 3 treatment groups, including 1X, 3X, and …


Region-Specific Hematological And Biochemical Reference Intervals For Southern Thai Fighting Bulls, Dhiravit Chantip, Nantaporn Chooruang, Kitikarn Sakuna, Niramol Thongtem, Wiruntita Bohman Mar 2025

Region-Specific Hematological And Biochemical Reference Intervals For Southern Thai Fighting Bulls, Dhiravit Chantip, Nantaporn Chooruang, Kitikarn Sakuna, Niramol Thongtem, Wiruntita Bohman

The Thai Journal of Veterinary Medicine

Accurate health assessments are vital for the performance and welfare of fighting bulls. Existing hematological and biochemical reference intervals (RIs) for cattle may not adequately reflect the unique characteristics of fighting bulls due to breed, age, and geographical differences. This study aimed to develop and apply region-specific RIs for hematological and biochemical parameters in fighting bulls from southern Thailand. A retrospective analysis of laboratory records was conducted on 1,460 healthy fighting bulls enrolled in an annual health check program at the Livestock Animal Hospital, Faculty of Veterinary Sciences, Rajamangala University of Technology Srivijaya, from January 2016 to December 2023. Blood …


Antituberculosis Potential Of Borrelidin Derivatives: An In Silico Molecular Docking And Molecular Dynamic Approach, Teni Ernawati, Donny Ramadhan, Faris Hermawan, Sasmito Wulyoadi, Bambang Marwoto, Ahmad Wibisana, Bambang Srijanto Mar 2025

Antituberculosis Potential Of Borrelidin Derivatives: An In Silico Molecular Docking And Molecular Dynamic Approach, Teni Ernawati, Donny Ramadhan, Faris Hermawan, Sasmito Wulyoadi, Bambang Marwoto, Ahmad Wibisana, Bambang Srijanto

The Thai Journal of Pharmaceutical Sciences

Background: The present tuberculosis (TB) treatment requires a significant time commitment, often lasting from 6 months to 2 years, with strict daily adherence. Non-compliance leads to drug resistance and suboptimal outcomes. Present research indicates that borrelidin shows potential activity against Mycobacterium tuberculosis, including strains that are resistant to first-line medications. Borrelidin has shown remarkable activity against M. tuberculosis H37Rv, with a minimum inhibitory concentration value of 3.12 μg/mL. Therefore, investigating the inhibition activity of borrelidin derivatives was essential for finding new anti-TB candidates. Objectives: This study aims to investigate the effects of 31 borrelidin derivative compounds …


Cost-Utility Analysis Of Riluzole Treatment Compared With Supportive Care For Patients With Amyotrophic Lateral Sclerosis, Thaiphat Rattana-Amonloet, Ampai Pimkrai, Piyameth Dilokthornsakul, Unchalee Permsuwan Mar 2025

Cost-Utility Analysis Of Riluzole Treatment Compared With Supportive Care For Patients With Amyotrophic Lateral Sclerosis, Thaiphat Rattana-Amonloet, Ampai Pimkrai, Piyameth Dilokthornsakul, Unchalee Permsuwan

The Thai Journal of Pharmaceutical Sciences

Background: In Thailand, riluzole, a drug used to treat amyotrophic lateral sclerosis (ALS), was costly and had not yet been included in the National List of Essential Medicines. In addition, no studies have been conducted on the cost-effectiveness of the drug. Objective: This study aimed to evaluate the cost-utility of riluzole in treating patients with ALS compared with supportive care from the perspective of societal and health-care providers. Methods: A Markov model was employed to analyze costs and benefits from a societal and the health-care provider’s perspective. Outcomes were measured in quality-adjusted life years (QALYs). The analysis calculated an incremental …


Preparation And Evaluation Of Mesoporous Celecoxib For Improved Antiarthritic Activity In Rodents, Reena I. Fernandaes, Sayani Bhattacharyya Mar 2025

Preparation And Evaluation Of Mesoporous Celecoxib For Improved Antiarthritic Activity In Rodents, Reena I. Fernandaes, Sayani Bhattacharyya

The Thai Journal of Pharmaceutical Sciences

Background: Celecoxib, a model anti-inflammatory drug, used in the management of arthritis exhibits limited oral bioavailability and slow onset of action due to its poor solubility. Objective: The present study explores a mesoporous drug delivery of celecoxib to investigate the efficacy of its antiarthritic activity in animal models, and develops a low-oral dose therapy. Materials and Methods: The solvent evaporation method was employed for the preparation of mesoporous delivery of celecoxib, using Syloid®, and Neusilin®, at a molar ratio of silica/ drug 1:2.5. The formulations were characterized for drug loading, in vitro drug release, and material …


The Antioxidant And Antiaging Activity Of Fig (Ficus Carica Linn) Leaf Ethanolic Extract In Vitro, Aji Winanta, Novita Zulaekhah, Perdana Priya Haresmita, Annisa Krisridwany, Rifki Febriansah, Inka Aprissa Mar 2025

The Antioxidant And Antiaging Activity Of Fig (Ficus Carica Linn) Leaf Ethanolic Extract In Vitro, Aji Winanta, Novita Zulaekhah, Perdana Priya Haresmita, Annisa Krisridwany, Rifki Febriansah, Inka Aprissa

The Thai Journal of Pharmaceutical Sciences

Background: Human organ systems can experience the aging process, one of which is the aging of the skin, characterized by dry, rough, or scaly skin, dullness, dark spots, and wrinkles. Previous studies have found that fig leaves contain compounds that have the potential to be anti-aging.
Objectives: This study aimed to determine the potential of fig leaves (Ficus carica Linn) as an anti-aging agent by examining their antioxidant activity, elastase inhibition, and antioxidative stress activity against hydrogen peroxide (H2O2). Materials and Methods: The phytochemicals in fig leaf ethanol extract were identified using phytochemical screening tests, …


Enhancing Topical Drug Delivery Of Apremilast Through Niosomal Gel Formulation: Ex Vivo Skin Permeation And In Vivo Evaluation For Psoriasis, Megha Shyam Matlapudi, Anka Rao Areti, Yukti Jaiswal, Veeresh Bantal, Raghavender Medishetti Mar 2025

Enhancing Topical Drug Delivery Of Apremilast Through Niosomal Gel Formulation: Ex Vivo Skin Permeation And In Vivo Evaluation For Psoriasis, Megha Shyam Matlapudi, Anka Rao Areti, Yukti Jaiswal, Veeresh Bantal, Raghavender Medishetti

The Thai Journal of Pharmaceutical Sciences

Background: Psoriasis is a dynamic and chronic disease characterized by inflammatory changes and an increased rate of keratinocyte proliferation leading to the formation of erythematous scleroderma plaques with a silvery sheen. The existing therapies come with shortcomings in terms of effectiveness and leave behind a trail of side effects. Hence, there is a need of alternative therapeutic measures. Objectives: This study aimed to assess the therapeutic potential of Apremilast Niosomal Gel (APR Nio Gel) in treating psoriasis, comparing its effectiveness with conventional gel (APR Gel) and oral suspension (APR Oral) formulations. Materials and Methods: Apremilast niosomes were prepared by thin …


Study Of Laws And Regulations Related To The Management Of Florfenicol Detection Cases In Swine, Shinnawat Saengungsumalee Mar 2025

Study Of Laws And Regulations Related To The Management Of Florfenicol Detection Cases In Swine, Shinnawat Saengungsumalee

The Thai Journal of Pharmaceutical Sciences

Background: Florfenicol, an antibiotic permitted in veterinary medicine, currently lacks an established maximum residue limit (MRL) in meat products in Thailand, effectively mandating undetectable residue levels. In May 2024, Thailand Pesticide Alert Network reported florfenicol residues in swine, raising concerns about consumer safety, rational veterinary drug use, and the potential for antimicrobial resistance (AMR). Addressing these issues involves multiple laws, decrees, and regulations across various agencies. Objectives: To analyze laws and regulations managing florfenicol residue detection in swine. Materials and Methods: This documentary research examines relevant laws, regulations, and measures for florfenicol in livestock and compares Thailand’s regulations with those …


Evaluating Asthma Education: A Comparison Of Whatsapp-Based Digital Interventions And Traditional Techniques, Rama Parthasarathy, Jayakumar Rajagopal, Sona Primuha Sugumaran, Sharon Angelin Johnson, Sai Shyam Kumar Nappa Selvam, Karthikeyan Ramaraju Mar 2025

Evaluating Asthma Education: A Comparison Of Whatsapp-Based Digital Interventions And Traditional Techniques, Rama Parthasarathy, Jayakumar Rajagopal, Sona Primuha Sugumaran, Sharon Angelin Johnson, Sai Shyam Kumar Nappa Selvam, Karthikeyan Ramaraju

The Thai Journal of Pharmaceutical Sciences

Background and Aims: Asthma is a chronic lung disease affecting people of all age group, which is characterized by inflammation and muscle tightening around the airway. Coughing, wheezing, and shortness of breath are the symptoms. The main complication faced by asthma patient is poor medication adherence; to overcome this patient counseling was performed. In this patient education was given through both digital and direct approaches. It is important to find out whether the above-mentioned approaches improve medication adherence. This research specifically investigates whether digital approaches through WhatsApp can directly improve asthma control compared to traditional methods. Methods: A prospective …


Effect Of Feeding A Saccharomyces Cerevisiae Fermentation Product On Immune Response To Vaccines Against Newcastle Disease Virus, Avian Influenza Virus, And The Prevalence Of Chronic Respiratory Disease And Coccidiosis In Chickens Raised In A Low Biosecurity Production System, Bui Thi Hien, Ho Thi Dung, Pham Hoang Son Hung, Le Duc Thao, Nguyen Van Chao, Tran Quang Vui, Nguyen Thi Hoa, Anjan Mondal, Nsereko Victor, Le Dinh Phung Mar 2025

Effect Of Feeding A Saccharomyces Cerevisiae Fermentation Product On Immune Response To Vaccines Against Newcastle Disease Virus, Avian Influenza Virus, And The Prevalence Of Chronic Respiratory Disease And Coccidiosis In Chickens Raised In A Low Biosecurity Production System, Bui Thi Hien, Ho Thi Dung, Pham Hoang Son Hung, Le Duc Thao, Nguyen Van Chao, Tran Quang Vui, Nguyen Thi Hoa, Anjan Mondal, Nsereko Victor, Le Dinh Phung

The Thai Journal of Veterinary Medicine

This study was carried out in a low biosecurity production system to explore the effects of a Saccharomyces cerevisiae fermentation product (SCFP) on immune responses to vaccination against Newcastle disease virus (NDV) and Avian influenza (H5N1) and prevalence of common diseases in chickens including chronic respiratory disease (CRD) and coccidiosis. One hundred and ninety two 1-day-old chickens were randomly assigned into control (a standard basal diet) and treatment (a standard basal diet containing 1.25 kg/MT of Diamond V XPC™ – a Saccharomyces cerevisiae fermentation product). Immunity data on antibody titers to NDV and H5N1 were collected at 3 weeks and …


Antibiotic Resistance Profile Of Enterobacteriaceae Isolated From Healthy Pigs In The Republic Of Armenia, Yura Shirvanyan, Irma Artushyan, Lilit Hovsepyan, Ashkhen Shirvanyan, Elmira Ghazaryan, Tigran Markosyan Mar 2025

Antibiotic Resistance Profile Of Enterobacteriaceae Isolated From Healthy Pigs In The Republic Of Armenia, Yura Shirvanyan, Irma Artushyan, Lilit Hovsepyan, Ashkhen Shirvanyan, Elmira Ghazaryan, Tigran Markosyan

The Thai Journal of Veterinary Medicine

The rising prevalence of antimicrobial resistance (AMR) among Enterobacteriaceae in livestock presents a significant threat to both animal and human health. This study investigates the antibiotic resistance profiles of Enterobacteriaceae isolated from 160 samples collected from the lymph nodes of healthy pigs in Armenia. Fifty isolates were identified, including Escherichia coli (24), Klebsiella spp. (10), Salmonella spp. (6), Raoultella ornithinolytica (4), Pseudomonas aeruginosa (4), and Proteus mirabilis (2). Resistance was evaluated using the disk diffusion method against 22 antibiotics from nine classes. Alarmingly, 94.5% of isolates were resistant to clarithromycin and 90.3% to erythromycin, while resistance to cephalothin and amoxicillin …


The Advanced Strategies Of Human And Donor Milk Fortification And Its Effect On Long-Term Outcome In Preterm Babies, Ashwini Lakra, Mahaveer Singh Lakra, Ishani Arora, Heena Bhandekar, Amar Taksande, Roshan Prasad, Mayur Wanjari Mar 2025

The Advanced Strategies Of Human And Donor Milk Fortification And Its Effect On Long-Term Outcome In Preterm Babies, Ashwini Lakra, Mahaveer Singh Lakra, Ishani Arora, Heena Bhandekar, Amar Taksande, Roshan Prasad, Mayur Wanjari

Chulalongkorn Medical Journal

Poor growth in intrauterine and extrauterine life and inadequate protein supplementation in babies during the first weeks of premature babies are linked to long-term growth failure and poor brain development. The calorie requirements of premature newborns cannot always be fulfilled, even with routine and traditional fortification. This is because traditional fortification procedures rely on the presumed well-known composition of human milk rather than the calculated one. The protein content of mothers' milk of preterm babies varies, decreases with breastfeeding duration, and differs with donor human milk being preserved in milk banks for a long duration. Newer fortification techniques are needed …


Appropriate International Normalized Ratio Follow-Up Interval In Patients With Atrial Fibrillation Taking Warfarin, Komsing Methavigul, Jirayu Sutasanasuang Mar 2025

Appropriate International Normalized Ratio Follow-Up Interval In Patients With Atrial Fibrillation Taking Warfarin, Komsing Methavigul, Jirayu Sutasanasuang

Chulalongkorn Medical Journal

Background: The international normalized ratio (INR) is recommended to be followed up every four-week intervals in patients with atrial fibrillation (AF) taking warfarin. However, data about the appropriate INR follow-up interval are lacking in those patients.

Objective: We aimed to investigate the appropriate INR follow-up intervals in AF patients receiving warfarin between 6-week and 12-week intervals of follow-up appointments.

Methods: We retrospectively enrolled patients with AF taking warfarin at the Central Chest Institute of Thailand between January 2017 to May 2023. The primary outcome was time in therapeutic range (TTR) in each group of follow-up interval and secondary outcome …


Antioxidant And Chemotherapeutic Synergy: Triphala Enhances Doxorubicin Cytotoxicity In Breast Cancer Cells And Reduces Toxicity In Non-Tumorigenic Cells, Supamas Charucharana, Poonlarp Cheepsunthorn Ph.D., Chalisa Louicharoen Cheepsunthorn Ph.D. Mar 2025

Antioxidant And Chemotherapeutic Synergy: Triphala Enhances Doxorubicin Cytotoxicity In Breast Cancer Cells And Reduces Toxicity In Non-Tumorigenic Cells, Supamas Charucharana, Poonlarp Cheepsunthorn Ph.D., Chalisa Louicharoen Cheepsunthorn Ph.D.

Chulalongkorn Medical Journal

Background: The combining of antioxidants with chemotherapy is increasingly explored to minimize toxicity in non-cancerous cells during breast cancer treatment. Triphala (TPL), a Thai herbal compound rich in antioxidants, shows potential as a complementary candidate for breast cancer chemotherapy.

Objective: This study investigated the combined effects of TPL and low-dose doxorubicin (DOX) on human breast cancer and non-tumorigenic mammary epithelial cells.

Methods: TPL’s bioactive compounds were analyzed via high-performance liquid chromatography (HPLC). Cell viability and reactive oxygen species (ROS) levels were assessed in breast cancer (MDA-MB-231, MCF-7) and epithelial (MCF-10A) cells using thiazolyl blue tetrazolium bromide (MTT) and chloromethyl 2′,7′-dichlorodihydrofluorescein …


Blood Tnf-Α And Gabra-1 Levels In Individuals With Poor Ovarian Response Underwent In Vitro Fertilization Program, Gadsara Ruangprachum, Paweena Thuwanut, Wisan Sereepapong, Vorasuk Shotelersuk, Siraprapa Tongkobpetch, Porntip Sirayapiwat Mar 2025

Blood Tnf-Α And Gabra-1 Levels In Individuals With Poor Ovarian Response Underwent In Vitro Fertilization Program, Gadsara Ruangprachum, Paweena Thuwanut, Wisan Sereepapong, Vorasuk Shotelersuk, Siraprapa Tongkobpetch, Porntip Sirayapiwat

Chulalongkorn Medical Journal

Background: Poor ovarian response (POR) to ovarian stimulation during in vitro fertilization (IVF) program remains a critical issue contributing to decreased ovarian reserve and cancellation of IVF cycles. Nevertheless, the complete etiology of PRO condition remains inadequately understood.

Objectives: This research primarily aimed to compare levels of blood pro-inflammatory cytokine (TNF-α) and apoptotic marker (GABRA-1) between those exhibiting normal ovarian response (NOR) and those with poor ovarian response during IVF program.

Methods: A cross-sectional study involving whole blood collection from 25 participants was conducted (15 individuals in NOR group and 10 in POR group). Relative gene expression levels of blood …


Reliability And Validity Of Thai Version Genital Appearance Satisfaction (Gas) Questionnaire, Suvit Bunyavejchevin, Thanawat Sangnucktham, Purim Ruanphoo Mar 2025

Reliability And Validity Of Thai Version Genital Appearance Satisfaction (Gas) Questionnaire, Suvit Bunyavejchevin, Thanawat Sangnucktham, Purim Ruanphoo

Chulalongkorn Medical Journal

Background: GAS questionnaire is constructed to measure feelings towards women’ own genitals in a broader spectrum. Thai language GAS questionnaire will be useful for clinical and research purpose.

Objectives: The aim of this study was study the reliability and validate the Thai version GAS questionnaire.

Materials and methods: Ninety Thai women attending the gynecologic outpatient clinic at King Chulalongkorn Memorial hospital were recruited between July 2017 to June 2018 in this study. Ten participants dropped out because they did not answer the second questionnaire. The original English-version of GAS questionnaire was translated into Thai version and backward translated …


Quality Control Of Clinical Protocols Of Ct Using The Accreditation Phantom, Walaiporn Suksancharoen, Apawadee Chakrapong, Sakultala Ruenjit, Anchali Krisanachinda Mar 2025

Quality Control Of Clinical Protocols Of Ct Using The Accreditation Phantom, Walaiporn Suksancharoen, Apawadee Chakrapong, Sakultala Ruenjit, Anchali Krisanachinda

Chulalongkorn Medical Journal

Background: The daily quality control of the Computed Tomography system consists of the measurement of the accuracy of CT Number and the artifact evaluation. The annual quality control includes the clinical protocol review. The CT radiologist is responsible for ensuring that all Quality Assurance (QA) requirements are met. The clinical team reviews and manages the CT protocol to deliver the appropriate radiation dose to the patient for each examination.

Objectives: To verify CT Number Accuracy, to review clinical protocols and to verify that the low-contrast performance of clinical protocols is adequate for diagnosis.

Methods: American College of Radiology (ACR) CT …