Medicine and Health Sciences Commons^™

Comparison Of Blood And Urinary Ketamine Profiles Among Different Causes Of Death In Thai Postmortem Cases, Supanida Leungsukjaroen, Sunitda Khawthong, Peerayuht Phuangphung

Chulalongkorn Medical Journal

Background: Ketamine is a substance that is commonly abused, especially in young adults. Blood and urinary ketamine profiles are important for the interpretation of causes of death. Objective: To compare blood and urinary ketamine profiles between different causes of death in Thai postmortem cases.

Methods: A cross-sectional study was conducted in 40 Thai postmortem cases whose urine samples tested positive for ketamine. Sex, age, cause of death, manner of death, blood alcohol concentration (BAC), and concomitant drugs found with ketamine in subjects were recorded for each case. Blood and urinary ketamine and its two metabolites (norketamine and dehydronorketamine …

The Comparison Of Lung Shunt Fraction Calculation Using Tc-99m Maa Planar And Spect/Ct Imaging For Y-90 Radioembolization, Nut Noipinit, Thunyaluk Sawatnatee, Benchamat Phromphao, Peangtawan Ratsameechot, Sutida Thiambandit, Tanawat Sontrapornpol

Chulalongkorn Medical Journal

Background: The evaluation of hepatopulmonary blood vessels with Technetium-99m macroaggregated albumin (Tc-99m MAA) scintigraphy before radioembolization with Yttrium-90 (Y-90) microspheres is a test to assess and prevent radiation pneumonitis. It was determined by the lung shunt fraction (LSF) which was calculated from a planar and SPECT/CT images. This study aimed to compare of LSF calculation from Tc-99m MAA planar and SPECT/CT images for Y-90 radioembolization treatment of liver tumors. Methods: A total of 64 patients (42 men and 22 women, mean age 64 ± 12.5 years) who underwent Tc-99m MAA scanning between 2015 and 2022 were enrolled. LSF was calculated …

Prevalence Of Carbapenem-Resistant Klebsiella Pneumoniae In King Chulalongkorn Memorial Hospital, 2019-2023, Napawan Punakabutra, Thanittha Wongkejkit, Nopphon Wuthinantiwong, Tanittha Chatsuwan

Chulalongkorn Medical Journal

Background : Carbapenem-resistant Klebsiella pneumoniae(CR-KP) poses a significant threat to global public health, contributing to high rates of morbidity and mortality.

Objective : The aim of this study was to investigate the prevalence of CR-KP isolated at King Chulalongkorn Memorial Hospital from April 2019 to December 2023, focusing on its distribution across varoius hospital units, including in-patient (IPD), out-patient (OPD), emergency (ER), and intensive care units(ICU).

Methods : A total of 8,983 K. pneumoniae isolates from patients aged > 15 years at King Chulalongkorn Memorial Hospital between April 2019 and December 2023 were studied. The antimicrobial susceptibility to carbapenems was …

Dual Role Of Triphala Extracts In Breast Cancer Therapy: Enhanced Paclitaxel Cytotoxicity By Ethanolic Extract And Cytoprotection By Aqueous Extract, Supamas Charucharana, Poonlarp Cheepsunthorn Ph.D., Chalisa L. Cheepsunthorn Ph.D.

Chulalongkorn Medical Journal

Background: Combining antioxidants with chemotherapy is an emerging strategy to reduce chemotoxicity in normal cells. Triphala (TPL), a polyphenol-rich Thai herbal formulation, has shown promise in enhancing chemotherapy efficacy, but its interaction with paclitaxel (PX) in breast cancer treatment remains underexplored.

Objective: This study evaluates the effects of aqueous (TPL-w) and ethanolic (TPL-a) TPL extracts combined with low-dose PX on breast cancer cells and non-tumorigenic mammary epithelial cells.

Methods: The bioactive components of TPL-w and TPL-a were identified using high-performance liquid chromatography (HPLC). Thiazolyl blue tetrazolium bromide (MTT) and chloromethyl 2′,7′-dichlorodihydrofluorescein diacetate (CM-H₂DCFDA) assays assessed cell viability and …

Dengue At Photharam Hospital: One Among Ten Clinical Trial Sites Of The World's First Dengue Vaccine, Anongrat Tiawilai, Chawin Tiawilai, Thawat Tiawilai, Nattachai Srisawat, Umaporn Limothai, Terapong Tantawichien, Usa Thisyakorn

Chulalongkorn Medical Journal

Background: Dengue, a viral disease transmitted by vectors, is widespread worldwide, impacting more than 120 nations. In 2019, a concerning 5.2 million dengue cases were reported, with Asia bearing 70% of the global burden. Half of the global population faces the risk of dengue.

Objectives: The goal of this research was to illustrate the epidemiological pattern of dengue patients admitted to Photharam Hospital in Ratchaburi province, Thailand, one of the ten clinical trial sites for the world's first dengue vaccine.

Methods: Data from dengue patients admitted to Photharam Hospital, a provincial healthcare center in Ratchaburi province, Thailand, covering the period …

Incidence Of Cytogenetic Abnormalities Detected By Fish Analysis In Multiple Myeloma Cases: A Seven-Year Study From A Cytogenetic Laboratory In King Chulalongkorn Memorial Hospital, Thailand (2018–2024), Montakarn Tansatit, Nutcharee Jongpornchai, Suwannee Songchart, Kittipornpan Krajokpap, Hudadini Da-Oh

Chulalongkorn Medical Journal

Background: Multiple myeloma (MM) is a genetically heterogeneous plasma cell malignancy with cytogenetic abnormalities influencing prognosis and treatment outcomes. Fluorescence in situ hybridization (FISH) is crucial for detecting clinically significant abnormalities, including IGH translocations and deletions (e.g., del(17p)), particularly in non-dividing plasma cells. However, cost and accessibility challenges limit comprehensive testing in resource-constrained settings like Thailand. Objectives: To investigate the incidence of cytogenetic abnormalities detected by FISH in MM cases over seven years in a Thai population, highlighting regional trends and barriers to comprehensive testing. Methods: A retrospective analysis was conducted on 360 bone marrow samples from MM patients between …

Pulse Diagnosis In Thai Traditional Medicine: Comparing Tri-Dhātu Characteristics In Each Innate Body Element Between Experts And Device, Athippat Tantiwongsekunakorn, Suksalin Booranasubkajorn, Thanaphak Chaopeerapong, Angkana Apichartvorakit, Pravit Akarasereenont

Journal of Health Research

Background: Pulse diagnosis in Thai Traditional Medicine (TTM) evaluates the balance of the Tri-Dhātu—Vata, Pitta, and Semha—and their interaction with innate body elements (Dhātu Chao Ruean; DCR). Despite its clinical significance, scientific evidence and quantitative tools remain limited. This study aimed to compare Tri-Dhātu pulse characteristics across different DCR types using expert assessment and the DMP-Life™ pulse diagnostic device.

Method: One-way ANOVA with post hoc analysis was applied to data from 159 participants, each evaluated at six pulse positions for shape, depth, power, and rhythm by Applied Thai Traditional Medicine (ATM) experts and the DMP-Life™ device.

Results: There were no …

Classification Of Dental Adverse Events Using Iterative Qualitative Analysis, Kiti Siriwatana, Sathirakorn Pongpanich

Journal of Health Research

Background: Effective incident reporting systems (IRS) are essential in dentistry for identifying and preventing adverse events (AEs), with standardized classifications ensuring consistent incident categorization. This study aimed to develop and validate a classification system for dental patient safety incidents based on a 5-year case study at the Dental Hospital at Chulalongkorn University, Thailand.

Methods: An iterative qualitative approach was used. A literature review explored existing accreditation standards and AE classification systems. Incident reports from 2018–2022 informed a draft classification system aligned with Thailand’s National Reporting and Learning System and accreditation standards. Reports from 2023 were used for validation. An expert …

Extended-Release Buprenorphine With Bupivacaine Effectively Provides Postoperative Analgesia In A Mouse Laparotomy Model, Monika K. Huss, Amber Kerk, Renee Cotton, Helen Chum, Michael Hsieh, Katechan Jampachaisri, Patrick Sharp, Cholowat Pacharinsak

The Thai Journal of Veterinary Medicine

Multimodal analgesia is widely encouraged for major survival surgery. This facilitates lower doses of individual drugs, thereby reducing side effects. Extended-release analgesics offer sustained analgesia coverage, prevent drug dosing nadirs, and reduce stress. Studies evaluating multimodal and extended-release analgesia combinations for major survival surgery in mice are limited. We compared the analgesic effect of bupivacaine and extended-release buprenorphine (Bupi-ER) to bupivacaine and buprenorphine HCl (Bupi-HCl). We hypothesized that preoperative Bupi-ER would provide more effective analgesia than Bupi-HCl. Mice were randomly assigned to 1 of 2 treatment groups: bupivacaine (2 mg/kg, local infiltration, once) with either 1) extended-release buprenorphine (0.6 mg/kg, …

Antimicrobial Susceptibility Profiles (Mic And Mmc) Against Mycoplasma Gallisepticum And M. Synoviae Isolated From Chicken Farms In Thailand, Kriengwich Limpavithayakul, Alongkorn Amonsin, Nataya Charoenvisal, Arithat Limsatanun, Katanyu Yangsuk, Sumrit Toopiya, Füsun Güngör, Esther Schonewille, Javier Uriarte, Somsak Pakpinyo

The Thai Journal of Veterinary Medicine

Mycoplasma gallisepticum (MG) and M. synoviae (MS) are important pathogens causing significant economic losses in poultry production. Disease prevention and control strategies include vaccination, antimicrobial therapy, and strict biosecurity measures. The present study provides, for the first time, both minimum inhibitory concentration (MIC) and minimum mycoplasmacidal concentration (MMC) values as antimicrobial susceptibility profiles of Thai MG and MS field isolates. This study aimed to evaluate the susceptibility of five MG and ten MS isolates to various antimycoplasma drugs: doxycycline, lincomycin-spectinomycin, tiamulin, tilmicosin, tylosin, and tylvalosin, using a microdilution broth assay. For MG isolates, tilmicosin had the highest mean MIC (12.5 …

Prevalence And Risk Factors Of Concurrent Osteoarthritis And Urolithiasis In Dogs In Thailand (2018–2020), Faiz Ihsanul Kamil, Kumpanart Soontornvipart

The Thai Journal of Veterinary Medicine

Osteoarthritis is a degenerative joint disease that significantly impacts dog health, often leading to chronic pain, reduced mobility, and behavioral changes that may predispose dogs to secondary conditions such as urolithiasis. This study aimed to investigate the association between osteoarthritis and urolithiasis in dogs using radiographic imaging data collected from the Small Animal Teaching Hospital, Chulalongkorn University, Thailand, over a three-year period (January 2018 to December 2020). A total of 16,377 dogs were included, and cases of osteoarthritis, urolithiasis, or the concurrent occurrence of both conditions were identified through a systematic database review. Binary logistic regression models were used to …

Monitoring Of African Horse Sickness Virus-Specific Antibodies In Horses, Northeastern Thailand, Napawan Bunpapong, Kitikhun Udom, Ekkapat Chamsai, Patchara Phuektes, Suphattra Jittimanee, Suphannika Phutthachalee, Supassama Chaiyawong, Kamonpan Charoenkul, Alongkorn Amonsin Prof. Dr.

The Thai Journal of Veterinary Medicine

African horse sickness (AHS) is caused by infection with the African horse sickness virus (AHSV). In March 2020, AHS was first reported in Thailand due to the importation of subclinically infected host animals, such as zebras. In this study, we conducted a serological survey for AHSV-specific antibodies across 21 horse farms in the northeastern provinces (n=3) of Thailand. A total of 600 serum samples were collected for cross-sectional (n = 292) and longitudinal serological monitoring (n = 308). A cross-sectional study was conducted in 2020, during which serum samples (n = 292) were collected and tested for AHS antibodies using …

Effects Of 25-Hydroxyvitamin D₃ Supplementation As A Partial Replacement For Vitamin D₃ On Laying Performance, Egg Quality, And Bone Traits In Late-Stage Laying Hens, Morakot Nuntapaitoon, Nan Choisunirachon, Somporn Techangvamsuwan, Jiramate Jittidecha

The Thai Journal of Veterinary Medicine

The objective of this study was to assess the impact of dietary 25-hydroxy vitamin D₃ (25OHD₃) supplementation during the late laying hens on egg quality, hen performance and bone computerized tomography (CT) scanning parameters. In total, 24,862 Hy-Line Brownmax hens of 61 weeks old were randomly divided into two groups: the control group (n = 12,368) received a diet containing vitamin D₃ at 3,000 IU/kg, and the treatment group (n = 12,494) received a diet containing vitamin D3 at 1,500 IU/kg and 25OHD₃ at 1,500 IU/kg. The dietary intervention from 61 weeks of age to …

Evaluation Of Antimicrobial And Wound Healing Activities Of Jatropha Podagrica Extracts, Reawfang Sriyom, Arunporn Itharat, Onmanee Prajuabjinda, Sumalee Panthong, Pakakrong Thongdeeying, Metar Siriwattanasathorn, Maneewan Panthong, Neal M. Davies

The Thai Journal of Pharmaceutical Sciences

Background: Jatropha podagrica has been traditionally used to treat skin infections and promote wound healing. However, there is currently no scientific research validating its antimicrobial or wound-healing properties.
Objectives: This study aimed to evaluate the antimicrobial and wound-healing activities of various extracts from all parts of J. podagrica, using different solvents. In addition, the chemical composition of the most effective extract was analyzed by Gas Chromatography-Mass Spectrometry (GC-MS).

Materials and Methods: The leaves, stem, and root of J. podagrica were extracted using hexane, 95% ethanol, ethanol-soluble hexane residue, and aqueous decoction. The antimicrobial effects of the extracts were assessed …

Exploring The Link Between Physicians’ Familiarity And Biosimilar Prescribing In Thailand, Ekapong Kachai, Chaoncin Sooksriwong, Wanruchada Katchamart, Tuangrat Phodha

The Thai Journal of Pharmaceutical Sciences

Background: Despite the availability of various biosimilars in Thailand, the link between physicians’ familiarity and biosimilars prescribing practice remains still unclear.

Objectives: This study aimed to find the association between physicians’ familiarity and biosimilars prescribing practice among physicians in Thailand.

Methods: This research adopted an extended analysis framework, utilizing survey data from a pilot study on the surveillance of Thai physicians regarding biosimilar uptake. The familiarity with biosimilars among respondents was evaluated.

Results: The result showed that 82 respondents were included in the study. There was 79.3% of respondents indicated prescribing biosimilars. Overall, most respondents (75.6%) showed an “adequate” level …

Concurrent Use Of Skeletal Muscle Relaxants And Nsaids In Low Back Pain Management: A Critical Review Of Current Evidence And Future Directions, Rupesh A. Saindane, Nilima A. Thombre

The Thai Journal of Pharmaceutical Sciences

Low back pain (LBP) represents a leading cause of non-fatal disability globally. Its high prevalence and disabling nature highlight the urgent need for effective management strategies. The exact cause of LBP still remains unclear, and thus, its treatment remains symptomatic. LBP is commonly treated with non-steroidal anti-inflammatory drugs (NSAIDs) and skeletal muscle relaxants (SMRs). These agents are frequently used in combination to target both inflammation and muscle spasms. However, the clinical guidelines vary widely on the recommendation for the use of such combination therapy. The present review evaluates evidence from randomized clinical trials and systematic reviews on the concurrent use …

Pharmacogenetic-Guided Antiplatelet Therapy For Personalized Medicine In Patients With Stroke And Transient Ischemic Attack Without Cardioembolic Stroke: A Systematic Review Of Economic Evaluations, Nathapol Samprasit, Chamipa Phanudulkitti, Nattanichcha Kulthanachairojana, Jatapat Hemapanpairoa

The Thai Journal of Pharmaceutical Sciences

Background: Stroke is a major global public health burden. Ischemic stroke is the most common type of all stroke cases worldwide. Antiplatelet therapy is a key strategy for secondary prevention in patients with stroke and transient ischemic attacks (TIAs) without cardioembolic stroke. Dual antiplatelet therapy (DAPT) with clopidogrel is recommended in patients with early mild stroke or high-risk TIA, followed by long-term single antiplatelet therapy (SAPT). Clopidogrel is often used as an alternative for patients with aspirin resistance or intolerance. However, clopidogrel is a prodrug metabolized by the CYP2C19 enzyme, leading to variability in its effectiveness.

Objectives: This study aims …

A Review Of Overlapping Severe Cutaneous Adverse Reaction, Ploylarp Lertvipapath, Roongrat Piyananjaruhsri, Diana Karimee

The Thai Journal of Pharmaceutical Sciences

Severe cutaneous adverse reactions (SCARs) are life-threatening drug hypersensitivity reactions, including acute generalized exanthematous pustulosis (AGEP), drug reaction with eosinophilia and systemic symptoms (DRESS), Stevens–Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN). SCARs occur in approximately 0.1% of hospitalizations and have mortality rates ranging from 5% for AGEP to 5–35% for SJS/TEN. AGEP typically presents with acute erythematous areas, sterile pustules, fever, and neutrophilia within 48–72 h of drug exposure. In contrast, DRESS manifests as fever, facial edema, morbilliform rash, and exfoliative dermatitis, often accompanied by hematologic abnormalities and multi-organ involvement, including hepatitis, pneumonitis, and myocarditis. Moreover, SJS and TEN …

The Use Of Health And Herbal Products For Covid-19 Self-Prevention And Its Affecting Factors According To Theory Of Planned Behavior, Suppachai Insuk, Supanida Kittirattanasak, Mullika Sirithongkaset, Daranee Chiewchantanakit

The Thai Journal of Pharmaceutical Sciences

Introduction: Despite the World Health Organization’s recent declaration of the end of the COVID-19 pandemic, the lessons learned from the outbreak remain crucial for future public health responses. In Thailand, the pandemic’s impact led individuals to explore self-protection methods, including potentially ineffective health products. This study examined the prevalence of health and herbal products used for COVID-19 self-prevention, to identify the types of these products in use and to identify factors influencing their utilization.

Methods: A cross-sectional study surveyed 400 Thai participants aged 25–60 who had never contracted COVID-19. The study employed convenience sampling and self-administered online questionnaires based on …

Mechanistic Insights And Clinical Benefits Of Omega-3 Fatty Acids In Cardiovascular, Inflammatory, And Neurological Health, Anosh Tahir, Afshan Siddiq

The Thai Journal of Pharmaceutical Sciences

Background: Omega-3 polyunsaturated fatty acids (ω-3 PUFAs), particularly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are attributed with the capacity to prevent cardiovascular diseases (CVD), chronic inflammation, and neurodegenerative diseases. Their bioactive contribution consists on interfering with lipid metabolism, decreasing inflammation, and increasing neuroprotection. Still, the findings imply that there is a considerable need for greater clarification of their mechanisms and their application to clinical care.

Objectives: This narrative review is intended to discuss the potential target(s) of action, uses, and efficacy of ω-3 PUFAs in the context of CVD, inflammation, and neurodegenerative diseases.

Materials and Methods: This narrative review …

Genetic Characterization Of Lpai-H4n2 And H4n8 Viruses Recovered From Free-Grazing Ducks In Thailand, Supanat Boonyapisitsopa, Supassama Chaiyawong, Kamonpan Charoenkul, Kitikhun Udom, Ekkapat Chamsai, Napawan Bunpapong, Somsak Pakpinyo, Alongkorn Amonsin Prof. Dr.

The Thai Journal of Veterinary Medicine

nfluenza A viruses (IAVs) can infect birds and various mammals. In this study, we retrospectively isolated and characterized IAVs (n=8) from oropharyngeal and cloacal swab samples of free-grazing ducks collected during December 2018 to December 2021, by using egg inoculation and whole-genome sequencing. The IAVs could be subtyped as IAV-H4N2 (n = 3) and IAV-H4N8 (n = 5) using real-time RT-PCR assays. Genetic and phylogenetic analyses revealed that all eight genes of Thai IAV-H4 belong to the Avian Eurasian lineage. Both Thai IAV-H4N2 and IAV-H4N8 exhibited low pathogenic avian influenza (LPAI) characteristics and were susceptible to oseltamivir and amantadine. This …

Prevalence, Antimicrobial Resistance Characteristics And Virulence Genes Of Streptococcus Suis In Pigs In Upper Northern Thailand, Wanida Mala, Rangsiya Prathan, Si Thu Hein, Sunpetch Angkittitrakul, Asinamai Athliamai Bitrus, Rungtip Chuanchuen

The Thai Journal of Veterinary Medicine

This study aimed to investigate the prevalence, virulence genes and antimicrobial resistance of Streptococcus suis from pigs in Upper-Northern Thailand. A total of 768 nasal swabs were obtained from pigs at the municipal slaughterhouses in five provinces including Phayao (n=202), Nan (n=190), Chiang Rai (180), Chiang Mai (n=130), and Mae Hong Son (n=66) in 2018-2019. The prevalence of S. suis varied from 3.0%-9.4%, of which the highest prevalence was in Chiang Rai (9.4%) and Mae Hong Son (9.1%). Of all 59 isolates confirmed to be S. suis, serotype 8 (50.8%) was most commonly identified, followed by serotype 10 (3.4%), …

Short-Term Outcomes Of A Comprehensive Rehabiliation Program With Peripheral Magnetic Stimulation In Polyneuropathy: A Case Report, Tuangtip Surarangsit

Chulalongkorn Medical Journal

Polyneuropathy, a condition affecting the peripheral nervous system, often results in sensory and motor dysfunction in older adults. Treatment options include medications and various physical therapy modalities including Peripheral Magnetic Stimulation (PMS). However, evidence supported treating nerve dysfunction with PMS is limited. In this case, an 84-year-old male with a history of diabetes mellitus and osteoarthritis presented with bilateral lower extremity sensory and motor polyneuropathy, experiencing weakness, sensory deficits, and gait instability. After limited success with conventional treatments, a comprehensive rehabilitation program was implemented over four weeks, integrating PMS, occupational therapy, and advanced gait training. Following the intervention, light touch …

A Tubo-Ovarian Abscess In Aplastic Anemia Presenting As Fever Of Unknown Origin, Rashi Mittal, Saurabh Kumar Gautam, Prasan Kumar Panda, Latika Chawla

Chulalongkorn Medical Journal

This report describes a complex case of a tubo-ovarian abscess (TOA) presenting atypically as fever of unknown origin (FUO) in a young woman initially diagnosed with severe aplastic anemia. The case involved protracted febrile illness, heavy menstrual bleeding, and pancytopenia. Identification of an Escherichia coli tubo-ovarian abscess, rather than tuberculosis, emphasized the need for a thorough evaluation in atypical presentations of TOA. Negative tuberculosis tests highlighted the variety of possible microbial etiologies. The resolution of fever following drainage and tailored antibiotic therapy, along with timely surgical intervention, demonstrated the importance of specific management strategies in such cases. Awareness of the …

Combined Anterior Palatoplasty With Barbed Suspension Pharyngoplasty In The Treatment Of Obstructive Sleep Apnea, Patheemon Thanachaikun, Natamon Charakorn

Chulalongkorn Medical Journal

Background: Surgery is a treatment option for obstructive sleep apnea (OSA) patients for whom positive airway pressure therapy is not chosen. Various palatal surgical techniques have been developed. However, the medical literature has limited accounts concerning the use of combination of these techniques to improved outcomes.

Objective: The aim of this study is to assess the efficacy of a combined anterior palatoplasty (AP) and barbed suspension pharyngoplasty (BSP) in treating adult OSA.

Methods: Data of OSA patients who underwent the combined AP with BSP between July 2020 to May 2024 were retrospectively reviewed. The surgical outcomes, including apnea-hypopnea index (AHI), …

The Factors Affecting The Distribution Of Scorpions (Arachnida: Scorpions) In Iran, Hassan Nasirian

Chulalongkorn Medical Journal

Background: The distribution of scorpions is influenced by various factors that determine their presence and abundance in different regions. Understanding these factors is crucial for comprehending scorpion ecology and predicting their potential impact on ecosystems. Objective: These subtopics aim to provide an overview of the distribution of scorpions within Iran and the factors affecting their distribution, highlighting their ecological preferences and adaptations to different regions.

Methods: Forty-nine documents were collected from well-known indexing services, including Elsevier, Google Scholar, PubMed, ScienceDirect, Scopus, Springer, and Web of Science. After carefully studying the documents, they were classified into specific topics and discussed.

Results: …

Job Strain And Associated Factors Among Medical School Employees In Thailand: A Cross-Sectional Study, Jakarin Apisuttisin, Pornchai Sithisarankul, Jate Ratanachina

Chulalongkorn Medical Journal

Introduction: Mental health issues are rising among workers, often linked to job strain. Medical schools, with their diverse workforce including not only healthcare workers and educators but also support staff, are in demanding work environments and are susceptible to job strain. This study aimed to investigate the prevalence and associated factors of job strain among support staff at a medical school in Bangkok, Thailand.

Methods: A cross-sectional study of 721 support staff employed at a medical school in Bangkok, Thailand was conducted between May and July 2024. The questionnaire consisted of three sections including demographic data, work-related factors, and the …

Clinical Factors Predicting The Need For Biopsy In Children With Cervical Lymphadenopathy, Pornchai Achatsachat, Nimmita Srisan, Prapapan Rajatapiti, Katawaetee Decharun, Somboon Reukvibunsi, Paisarn Vejchapipat

Chulalongkorn Medical Journal

Background: Lymphadenopathy in children is often a diagnostic challenge for clinicians. It may be one symptom of many diseases including granulomatous diseases and malignancy. The cervical region is a commonly involved area in peripheral lymphadenopathy. Surgical biopsy often provides a definitive diagnosis but occasionally unnecessary in some cases.

Objectives: The objective was to describe children with cervical lymphadenopathy who underwent surgical biopsies and to determine clinical factors that can predict the likelihood of lymph nodes needing further management (LNFM) including granulomatous and malignant lymph nodes. Methods: Data of 87 children with cervical lymphadenopathy undergoing surgical biopsy were retrospectively reviewed. Descriptive …

Psychometric Evaluation Of The Thai Version Of Emotional Labor Scale (T-Els) In Thai Nurses, Vachira Posai, Wisarut Srisintorn, Paramee Thongsuksai, Chanokporn Jitpanya

Journal of Health Research

Background: Nurses often face emotional strain due to emotional labor (EL), which involves concealing or modifying genuine feelings to meet their job requirements. This response can lead to physical, psychological, and behavioral issues. The Emotional Labor Scale (ELS), originally in English, has not been translated into Thai, leaving its psychometric properties unexamined in the Thai context. This study aimed to translate the ELS into Thai and evaluate its psychometric properties among Thai nurses.

Methods: A cross-sectional study design was used. The 14-item scale, which includes surface acting, deep acting, and expression of naturally felt emotions dimensions, was translated using forward …

Predictive Model For Hemoglobin Levels Using Multiple Linear Regression, Dien Gusta Anggraini Nursal, Muhammad Daffa Atthariq Winata, Nohan Arum Romadlona, Noura Rizki, Sabillah Nasitoh, Muhammad Sakhi Baretta

Journal of Health Research

Background: Anemia is a condition in which the number of red blood cells or hemoglobin (Hb) levels fall below normal, limiting the ability of blood to transport oxygen effectively. This study aimed to develop a predictive model for Hb levels by identifying significant risk factors.

Method: This observational analytic study was conducted among 103 randomly selected students of Bung Hatta University in Padang, Indonesia. Data were collected with a questionnaire and a hemoglobin test between April to May 2024. Pearson’s correlation analysis and multiple linear regression were performed in this study.

Results: Bivariate analysis showed significant correlations between Hb levels …