Kinesiology Commons^™

Neural Response To Food Cues After Moderate And Vigorous Exercise In Women: A Randomized Crossover Trial, Jillesa Anderson

Theses and Dissertations

PURPOSE: This study examined the effect of different intensities of acute exercise on attention allocation to visual food cues, postexercise energy intake, and subjective measures of hunger in women. METHODS: This crossover study utilized treatment conditions that were randomized and counter-balanced. Fifty-two adult women, 18-29 years, were compared under three separate conditions: no exercise, 45 min of moderate-intensity exercise at 3.9 METs and 22.5 min of vigorous-intensity exercise at 7.8 METs. To measure attention allocation to visual food cues, participants were shown a passive viewing task consisting of a continual stream of pictures of food (high and low calorie) and …

Effects Of Transcutaneous Electrical Nerve Stimulation On Quadriceps Activation And Walking Mechanics In Patients With Anterior Knee Pain, Brian Wiseman, J. Ty Hopkins

Journal of Undergraduate Research

More than ten million people in the U.S. suffer from knee pain, and one in every two people may develop chronic knee pain by age 85.³ Knee pain is also 1 of 5 leading causes of disability among adults, and alters muscle function and walking mechanics, which in turn, decreases quality of life.⁶ To alleviate the effects of knee pain and its consequences, transcutaneous electrical nerve stimulation (TENS) is often used to decrease perceived pain⁵ and increase quadriceps activation.⁷ However, it is unclear whether these benefits could offer potential improvement for walking mechanics. Therefore, the purpose …

Morphology Of Human Myoblasts In Cultured Muscle Cells By The Novel Small Molecule Sgi, Ryan Matekel, Robert Hyldahl

Journal of Undergraduate Research

Muscle wasting is a symptom of cancer, AIDS, renal failure, heart failure, aging, prolonged bed rest, and has been seen in rodent models for burn, and kidney disease (Han, 2013). Muscle wasting negatively impacts quality of life by decreasing functional independence and increasing morbidity and mortality (Anker, 1997). Muscle wasting is an especially serious issue given that the body weight of an average human is 40-50 percent skeletal muscle (Han, 2013). Myostatin is a protein that negatively regulates muscle mass and is primarily expressed within skeletal muscle (Lee & McPherron, 2001). Genetic studies have shown that inhibition of myostatin signaling …

Effect Of Myostatin Pathway Inhibition On Fibroblast Activity Using A Novel Small Molecule, Seth Hampton, Dr. Robert Hyldahl

Journal of Undergraduate Research

Fibroblasts play a key role in repairing injured tissue by secreting collagen and growth factors into the tissue. In states of disease and overuse, fibroblast activity can become overly abundant and can lead to skeletal muscle fibrosis, decreasing strength and muscle elasticity. This fibrotic condition can lead to muscle wasting disorders, such as muscular dystrophies, that severely decrease the length and quality of life. Previous studies have shown that the TGF-beta signaling family directly increases fibroblast proliferation. It has also been shown that inhibition of myostatin, a member of the TGF-beta family, reduces symptoms of muscular dystrophies and decreases fibrosis. …

Evidence For Regulatory T Cell In Skeletal Muscle Repair, Amanda Gier, Robert Hyldahl

Journal of Undergraduate Research

Testing multiple immunohistochemistry protocols, I was unsuccessful at identifying Tregulatory cells in human skeletal muscle samples. A total of 5 months was dedicated to this original project before I was reassigned to look into the presence of CD8+ cells in skeletal muscle. The new project proved to be fruitful as I was able to confidently identify CD8+ cells and analyze their presence in the process of skeletal muscle repair. Furthermore, the data I collected has be incorporated into a paper Dr. Robert Hyldahl is currently working on titled “Skeletal muscle inflammation following repeated bouts of lengthening contractions in humans.”

Foot Strike Angle Changes During Shod, Minimalist, And Barefoot Running, And Correlation To Injury, Ani Henriksen, Dr. Sarah Ridge

Journal of Undergraduate Research

Running is a popular form of exercise. With high incidence of injury, runners are always looking for the next cure to stay injury free. Many webpages offer conflicting advice about shoes and foot strike. Although recommendations vary, barefoot running and use of minimalist shoes has increased. With the change in footwear, many runners have reported injuries from improper technique and repetitive loading. With the use of current technology we analyzed movements of the foot ignored by other studies. This project analyzed foot strike movement in the frontal plane to help us better understand the ideal foot strike technique for running …

Ambulation Speed And Corresponding Mechanics Are Associated With Changes In Serum Cartilage Oligomeric Matrix Protein, W. Matt Denning, Michael Becker Pardo, Jason G. Winward, Iain Hunter, Sarah T. Ridge, J. Ty Hopkins, C. Shane Reese, Allen C. Parcell, Matthew K. Seeley

Faculty Publications

Because serum cartilage oligomeric matrix protein (COMP) has been used to reflect articular cartilage condition, we aimed to identify walking and running mechanics that are associated with changes in serum COMP. Eighteen subjects (9 male, 9 female; age = 23 ± 2 yrs.; mass = 68.3 ± 9.6 kg; height = 1.70 ± 0.08 m) completed 4000 steps on an instrumented treadmill on three separate days. Each day corresponded to a different ambulation speed: slow (preferred walking speed), medium (+50% of slow), and fast (+100% of slow). Synchronized ground reaction force and video data were collected to evaluate walking mechanics. …

Blockade Of Tgf-Ss Signaling Through The Activin Type Iib Receptor With The Small Molecule, Sgi-1252, Jordan David Fuqua

Theses and Dissertations

Antagonism of the activin receptor signaling pathway represents a promising potential therapy for the muscular dystrophies and other muscle wasting disorders (i.e., cachexia or sarcopenia). Previous research has shown that antagonism of activin signaling promotes muscle growth, attenuates muscle wasting, and restores function in both wild type and diseased animals. Our laboratory has recently developed a novel small molecule (SGI-1252) that inhibits activin downstream (i.e., Smad2/3 phosphorylation) signaling. Purpose: In this study we determined how eight weeks of orally administered SGI-1252 affected TGF-ß signaling, whole body mass, individual limb muscle mass, and muscle fiber cross sectional area (CSA). Methods: Wild-type …

The Effect Of Foot Strengthening Exercise On Dynamic Function Of The Medial Longitudinal Arch In Runners: A Preliminary Report, Jarom Bridges

Theses and Dissertations

Therapeutic exercise has previously been shown to alter the static height of the medial longitudinal arch (MLA). It is still unknown, however, if these effects carry over into dynamic activities. PURPOSE: To determine if an 8-week foot strengthening exercise program increases static arch height and reduces vertical deformation of the MLA during mid-stance in running.METHODS: Thirty-four recreational runners (17 males, 17 females) have completed this ongoing study (age 24.06 ± 3.61 years, body mass 68.63 ± 12.95 kg, and height 173.34 ± 9.54 cm). To date, 22 subjects have been assigned to the control group (8 weeks of normal running) …

The Effect Of Aerobic Exercise Versus Inactivity On Nitric Oxide Concentration And Synthesis In An Elderly Population, Samantha Burton

Theses and Dissertations

CONTEXT: Nitric Oxide (NO) is an endothelial-derived vasoactive molecule that causes an increase in blood flow and oxygen delivery to tissue. A reduction in NO bioavailability has been found to occur in adults over the age of 60 and can be reversed pharmacologically by improving NO synthase (NOS) activity. Reversing these age-related changes with alternative interventions, such as aerobic exercise, has shown some promising results. OBJECTIVE: To quantify blood NO-bioavailability (as measured by blood nitrite levels) in a population of aerobically trained elderly men and compare these data to a group of age-matched, inactive individuals. In addition, we measured the …

Strength Training And Body Composition In Middle-Age Women, Rachelle Burrup

Theses and Dissertations

OBJECTIVE: The purpose of this study was to examine the relationship between strength training and body composition before and after controlling for several covariates. A cross-sectional study including 257 female subjects was conducted. METHODS: Subjects' level of involvement in strength training was determined via questionnaire. Body composition was assessed using dual energy X-ray absorptiometry (DXA). Diet was assessed using 7-d weighed food records. RESULTS: Strong linear relationships between subjects' level of involvement in strength training and body composition were identified. For each additional day of strength training reported per week, body fat was 1.32 percentage points lower (F = 14.8, …

The Effect Of Training In Minimalist Running Shoes On Running Economy, Sarah T. Ridge, Tyler Standifird, Jessica Rivera, A. Wayne Johnson, Ulrike H. Mitchell, Iain Hunter

Faculty Publications

The purpose of this study was to examine the effect of minimalist running shoes on oxygen uptake during running before and after a 10-week transition from traditional to minimalist running shoes. Twenty-five recreational runners (no previous experience in minimalist running shoes) participated in submaximal VO2 testing at a self-selected pace while wearing traditional and minimalist running shoes. Ten of the 25 runners gradually transitioned to minimalist running shoes over 10 weeks (experimental group), while the other 15 maintained their typical training regimen (control group). All participants repeated submaximal VO2 testing at the end of 10 weeks. Testing included a 3 …

Lower Extremity Neuromechanics During A Forward-Side Jump Following Functional Fatigue In Patients With Ankle Instability, Hyun Kim

Theses and Dissertations

Ankle instability (AI) and fatigue impair neuromuscular control as well as dynamic joint stability of the lower extremity. No one has comprehensively examined the effects of AI and fatigue on neuromechanics of the lower extremity during a functional activity. Deficits associated with AI and fatigue could be additive in increasing the risk for injury in patients with AI. PURPOSE: To examine the interaction of AI and fatigue on lower extremity muscle activity, kinematic, and kinetic patterns during a forward-side jump. METHODS: 25 AI (23.3 ± 1.9 yrs, 176.5 ± 10.5 cm, 70.9 ± 11.4 kg), and 25 matched control subjects …

Will Ultrasound Performed With The Rich-Mar Autosound™ Be As Effective At Increasing Tissue Temperature As Ultrasound Performed With A Traditional Machine?, Heather Diane Black

Theses and Dissertations

STUDY DESIGN: Randomized crossover experiment. OBJECTIVE: To determine whether the Rich-Mar AutoSound™ would be as effective as traditional ultrasound at increasing the temperature of the triceps surae muscle during a 10-min, 1 MHz, 1.0 W/cm2 ultrasound treatment. BACKGROUND: The AutoSound™ is a hands-free ultrasound device that is strapped on the body and left for the duration of the ultrasound treatment. It requires no clinician during the actual ultrasound treatment, thus freeing the clinician to perform other tasks and reducing clinician error during treatments. METHODS: 16 healthy subjects (6 males, 10 females, age = 22 ± 1.6 yrs, height = 173.2 …

Meat Intake And Insulin Resistance In Women Without Type 2 Diabetes, Larry A. Tucker, James D. Lecheminant, Bruce W. Bailey

Faculty Publications

Purpose. To examine the relationship between meat intake and insulin resistance (IR) in 292 nondiabetic women. Methods. IR was evaluated using the homeostasis model assessment (HOMA). Diet was assessed via 7-day weighed food records. Servings of very lean meat (VLM) and regular meat (meat) were indexed using the ADA Exchange Lists Program. Physical activity was assessed using accelerometers and body fat was measured using the Bod Pod. Results. Meat intake was directly related to HOMA (F = 7.4; P = 0.007). Women with moderate or high meat intakes had significantly higher HOMA levels than their counterparts. Adjusting for body fat …

Inhibition Of The Myostatin Signaling Pathway In Cultured Muscle Cells By A Novel Small Molecule, Ryan Matekel, Robert Hyldahl

Journal of Undergraduate Research

Muscle wasting is a symptom of cancer, AIDS, renal failure, heart failure, aging, prolonged bed rest, and has been seen in rodent models for burn, and kidney disease (Han, 2013). Muscle wasting negatively impacts quality of life by decreasing functional independence and increasing morbidity and mortality (Anker, 1997). Myostatin is a protein that negatively regulates muscle mass and is primarily expressed within skeletal muscle (Lee & McPherron, 2001). It exerts its effect by binding to a receptor and initiating a signaling cascade that involves phosphorylation of two kinase proteins called SMAD-2 and SMAD-3 (Sartori et al., 2009). Genetic studies have …

Slow Walking On A Treadmill Desk Does Not Negatively Affect Executive Abilities: An Examination Of Cognitive Control, Conflict Adaptation, Response Inhibition, And Post-Error Slowing, Michael J. Larson, James D. Lecheminant, Kaylie Carbine, Kyle R. Hill, Edward Christenson, Travis Masterson, Rick Lecheminant

Faculty Publications

An increasing trend in the workplace is for employees to walk on treadmills while working to attain known health benefits; however, the effect of walking on a treadmill during cognitive control and executive function tasks is not well known. We compared the cognitive control processes of conflict adaptation (i.e., congruency sequence effects—improved performance following high-conflict relative to low-conflict trials), post-error slowing (i.e., Rabbitt effect), and response inhibition during treadmill walking (1.5 mph) relative to sitting. Understanding the influence of treadmill desks on these cognitive processes may have implications for worker health and productivity. Sixty-nine individuals were randomized to either a …

Cognitive And Typing Outcomes Measured Simultaneously With Slow Treadmill Walking Or Sitting: Implications For Treadmill Desks, James D. Lecheminant, Michael D. Larson, Kyle Hill, Kaylie Carbine, Travis Masterson, Ed Christenson

Faculty Publications

Purpose

This study compared cognitive (attention, learning, and memory) and typing outcomes during slow treadmill walking or sitting. Seventy-five healthy individuals were randomly assigned to a treadmill walking group (n=37; 23 female) or sitting group (n=38; 17 female).

Methods

The treadmill walking group completed a series of tests while walking at 1.5 mph. The sitting group performed the same tests while sitting at a standard desk. Tests performed by both groups included: the Rey Auditory Verbal Learning Test and a modified version of the Paced Auditory Serial Attention Test. In addition, typing performance was evaluated.

Results

Participants in the treadmill …

Sex Differences In Whole Body Gait Kinematics At Preferred Speeds, Dustin A. Bruening, R. Frimenko, C. Goodyear, A. Fullenkamp

Faculty Publications

Studies on human perception have identified pelvis and torso motion as key discriminators between male and female gaits. However, while most observers would advocate that men and women walk differently, consistent findings and explanations of sex differences in gait kinematics across modern empirical studies are rare. In the present study we evaluated sex differences in whole body gait kinematics from a large sample of subjects (55 men, 36 women) walking at self selected speeds. We analyzed the data through comparisons of discrete metrics and whole curve analyses. Results showed that in the frontal plane, women walked with greater pelvic obliquity …

Dairy Consumption And Insulin Resistance: The Role Of Body Fat, Physical Activity, And Energy Intake, Larry A. Tucker, Andrea Erickson, James D. Lecheminant, Bruce W. Bailey

Faculty Publications

The relationship between dairy consumption and insulin resistance was ascertained in 272 middle-aged, nondiabetic women using a cross-sectional design. Participants kept 7-day, weighed food records to report their diets, including dairy intake. Insulin resistance was assessed using the homeostatic model assessment (HOMA). The Bod Pod was used to measure body fat percentage, and accelerometry for 7 days was used to objectively index physical activity. Regression analysis was used to determine the extent to which mean HOMA levels differed across low, moderate, and high dairy intake categories. Results showed that women in the highest quartile of dairy consumption had significantly greater …

Ground Forces Impact On Release Of Rotational Shot Put Technique, Niklas B. Arrhenius

Theses and Dissertations

In the shot put throw, the primary power is generated in the form of ground reaction forces as a result of action of the lower extremities (Coh, Stuhec, & Supej, 2008). The purpose of this study was to determine how the ground reaction force and ground contact time during the delivery phase of rotational shot put relates to the predicted distance of the throw. This will allow us to determine the optimal approach of force application for maximum throwing distance (Linthorne, 2001). Eight male subjects were used in this study (age 23 ± 4 y; body mass 123 ± 14 …

The Effects Of Worksite Health Promotion Programs On Employee Biometric Data, Jamie M. Pratt

Theses and Dissertations

INTRODUCTION: Worksite health promotion programs (WHPP) promote maintenance and changes of health-related behaviors of employees. Some companies opt to contract with a third party provider to implement a WHPP. PURPOSE: This study evaluated the participation rates, availability and use of health coaching, and changes in biometric data over a 2-year time period of employees in 13 companies for whom the WHPP was implemented by Wellness Corporate Solutions (WCS). METHODS: We had 2 years of biometric, health risk appraisal (HRA), or health coaching data on 4,473 employees. The statistical analysis included biometric screening data (percent body fat, body mass index (BMI), …

Microvascular Function In Metabolically Healthy Groups Differing In Bmi And Waist Circumference, Nathan R. Earl

Theses and Dissertations

BACKGROUND: Microvascular dysfunction (MD: impaired performance of blood flow, tissue perfusion, blood pressure, etc.) is one of the earliest stages in the progression of various chronic diseases. OBJECTIVE: The aim of this study was to determine if a difference in microvascular function existed between two metabolically healthy groups that differed in BMI and waist circumference. DESIGN: This study employed a causal comparative design, with two groups: I) normal weight (n =14, BMI 28 kg/m2). METHODS: Microvascular function was assessed by measuring skin blood flow (SkBF) using laser Doppler flowmetry during postocclusive reactive hyperemia (PORH). The area under the SkBF time …

A Randomized Controlled Trial To Study The Effects Of Breakfast On Energy Intake, Physical Activity, And Body Fat In Women, Gabrielle Marie Lecheminant

Theses and Dissertations

PURPOSE: The purpose of this study was to determine the effects of eating breakfast on energy intake, physical activity, body weight, and body fat in women who were nonhabitual breakfast eaters over a one-month period. METHODS: We tested 49 premenopausal, nonhabitual breakfast-eating women to compare the effects of eating breakfast versus not eating breakfast. Each participant was randomized to one of two conditions: breakfast or no breakfast. Breakfast eaters were required to eat within an hour and a half of awakening and had to be finished eating their breakfast meal by 8:30 A.M. Non-breakfast eaters were defined as not consuming …

Instrumented Figure Skating Blade For Measuring On-Ice Skating Forces, S A. Acuña, D M. Smith, J M. Robinson, J C. Hawks, P Starbuck, D L. King, Sarah T. Ridge, Steven Knight Charles

Faculty Publications

Competitive figure skaters experience substantial, repeated impact loading during jumps and landings. Although these loads, which are thought to be as high as six times body weight, can lead to overuse injuries, it is not currently possible to measure these forces on-ice. Consequently, efforts to improve safety for skaters are significantly limited. Here we present the development of an instrumented figure skating blade for measuring forces on-ice. The measurement system consists of strain gauges attached to the blade, Wheatstone bridge circuit boards, and a data acquisition device. The system is capable of measuring forces in the vertical and horizontal directions …

Unilateral Traditional Weight Lifting Generates Greatest Acute Upper Body Power Output, Evan H. Nakachi

Theses and Dissertations

Bilateral deficit (BLD) is a phenomenon where the force generated from simultaneous bilateral limb contractions is less than the sum force generated by separate right and left limb contractions. There have been many BLD studies, but the measures of force generation have predominantly been with isometric and isokinetic contractions. There are, however, no dynamic upper body isotonic unilateral weight lifting studies on acute power output. The purpose of this study was to determine acute power output between bilateral and unilateral weight lifting under the conditions of traditional and circuit weight lifting. Seventeen male BYU rugby players (age = 21.8 ± …

Downhill Treadmill Running Does Not Induce Muscle Damage In Fvb Mice, Brenda Benson

Theses and Dissertations

Downhill treadmill running is a commonly used method to cause exercise-induced muscle damage, especially in rodents. Previous studies have evaluated which muscles in rats are more prone to damage. However research using downhill run mice (DHR) has shown some inconsistencies in which muscle is best analyzed for damage. Purpose: The purpose of this study was to quantify the damage in various muscles in a mouse after a single bout of DHR. Methods: Male FVB mice (5 months) were injected with Evans Blue dye (EBD) and then either used as control (CON) or run downhill (-16°) at 20 meters per minute …

Neural Reactivity To Visual Food Stimuli In The Morning And Evening: An Fmri Study In Women, Travis Daniel Masterson

Theses and Dissertations

Background: Visual food stimuli have been shown to influence desire to eat and may influence overall energy intake. The purpose of this study was to determine the influence, if any, that time of day has on the neural response to visual food stimuli, as measured by functional magnetic resonance imaging (fMRI). Methods: Using a crossover design, 15 healthy women were scanned using fMRI while presented with low- and high-energy pictures of food, once in the morning (6:30–8:30 am) and once in the evening (5:00–7:00 pm). Diets were identical on both days of the fMRI scans and were verified using weighed …

The Effect Of Chronic Mild To Moderate Neck Pain On Neck Function As Measured By Joint Reposition Error And Tactile Acuity Of The Cervical Dermatomes, Kelly Martell Cheever

Theses and Dissertations

The purpose of this study was to observe the joint reposition error and tactile acuity of patients with chronic mild to moderate neck pain and compare those values to healthy controls to further investigate the effect of neck pain on neck function and the need for sensorimotor training in patients with chronic neck pain. In spite of some inconsistencies in the literature and methodology, both the two-point discrimination test and the joint reposition error test can give clinicians valuable, inexpensive and quick objective data that can be used in the diagnostic portion of an examination as well as in designing …

Validity Of Posturescreen Mobile® In The Measurement Of Standing Posture, Breanna Cristine Berry Hopkins

Theses and Dissertations

Background: PostureScreen Mobile® is an app created to quickly screen posture using front and side-view photographs. There is currently a lack of evidence that establishes PostureScreen Mobile® (PSM) as a valid measure of posture. Therefore, the purpose of this preliminary study was to document the validity and reliability of PostureScreen Mobile® in assessing static standing posture. Methods: This study was an experimental trial in which the posture of 50 male participants was assessed a total of six times using two different methods: PostureScreen Mobile® and Vicon 3D motion analysis system (VIC). Postural deviations, as measured during six trials of PSM …