Lighted Ear Curette, Kaitlin Klotzle, Kelsey Ashmore, Crysta Yamamoto, Katrina Elfrink, Cynthia Stoller

Williams Honors College, Honors Research Projects

The ear canal is a sensitive and small part of the human body that is prone to accumulate cerumen or lodge foreign bodies. In order to clean the ear canal or remove foreign bodies, three hands are required: one to brace the patient's head, one to maneuver the curette that is used to clean the ear, and one to hold a light source in order to make the small, dark area visible. Therefore, a design is needed that can allow a doctor to safely clean an ear with an instrument that only requires two hands. Furthermore, the design must have …

Simulation Of Human Ankle Trajectory During Stance Phase Of Gait, Leslie Castelino

Dissertations, Master's Theses and Master's Reports

A simulation was developed which mimics the human gait characteristics based on the input of an individual’s gait trajectory. This simulation also estimates the impedance of the human ankle based on the ground reaction forces measured by the force plate. This simulation will accept alterations of the following parameters: total body weight, weight of the shank, weight of the foot, trajectories of the shank and foot of the individual and orientation of the force plate, which would generate a new gait trajectory for the ankle during the stance phase of gait. The goal of this simulation was to validate the …

Finite Element Modeling Of The Plantar Fascia: A Viscohyperelastic Approach, Alexander Knapp

UNF Graduate Theses and Dissertations

The present work details the creation and analysis of a finite element model of the foot, wherein the plantar fascia was modeled as a viscohyperelastic solid. The objective of this work was to develop a fully functional CAD and Finite Element Model of the foot and plantar fascia for analysis by examining the transient stresses on the plantar fascia through the use of a viscohyperelastic material model. The model’s geometry was developed through the use of image processing techniques with anatomical images provided by the National Institutes of Health. The finite element method was used to analyze the transient response …

A Computational Study Of The Kinematics Of Femoroacetabular Morphology During A Sit-To-Stand Transfer, Brandon K. Marine

Theses and Dissertations

Computational modeling in the field of biomechanics is becoming increasingly popular and successful in practice for its ability to predict function and provide information that would otherwise be unobtainable. Through the application of these new and constantly improving methods, kinematics and joint contact characteristics in pathological conditions of femoroacetabular impingement (FAI) and total hip arthroplasty (THA) were studied using a lower extremity computational model. Patients presenting with FAI exhibit abnormal contact between the femoral neck and acetabular rim leading to surrounding tissue damage in daily use. THA is the replacement of both the proximal femur and acetabular region of the …

Nanocomposite Bioelectronics For Biopotential Enabled Prosthesis, Dong Sup Lee

Theses and Dissertations

Soft material-enabled electronics can demonstrate extreme mechanical flexibility and stretchability. Such compliant, comfortable electronics allow continuous, long-term measurement of biopotentials on the skin. Manufacturing of the stretchable electronic devices is enabled by the recent development combining materials transfer printing and microfabrication. However, the existing method using inorganic materials and multi-layered polymers requires long material preparation time and expensive processing cost due to the requirement of microfabrication tools and complicated transfer printing steps. Here, this study develops a new fabrication method of soft electronics via a micro-replica-molding technique, which allows fast production, multiple use, and low cost by avoiding microfabrication and …

A 3d Fem Comparative Study On The Impact Response Between Human Head And Nocsae Head Due To Free Fall, Amey S. Badhe

Dissertations, Master's Theses and Master's Reports

We all enjoy sports be it watching or playing. Concussion is well known topic when it comes sports related injuries. However, concussion and brain injury is not exclusive to sports and outdoor activities. Sometimes, even the impact due to slip and fall at small heights can cause serious damage to the head and brain. This report studies the response generated in the human head model and the commercially use dummy NOCSAE headform due to drop from height of 2, 3, 4 and 5 feet. Earlier studies have related brain kinetics and head kinematics to concussion and traumatic brain injury (TBI). …

Using Lower Extremity Muscle Activations To Estimate Human Ankle Impedance In The External-Internal Direction, Lauren N. Knop

Dissertations, Master's Theses and Master's Reports

For millions of people, mobility has been afflicted by lower limb amputation. Lower extremity prostheses have been used to improve the mobility of an amputee; however, they often require additional compensation from other joints and do not allow for natural maneuverability. To improve upon the functionality of ankle-foot prostheses, it is necessary to understand the role of different muscle activations in the modulation of mechanical impedance of a healthy human ankle. This report presents the results of using artificial neural networks (ANN) to determine the functional relationship between lower extremity electromyography (EMG) signals and ankle impedance in the transverse plane. …

Design And Evaluation Of Pediatric Gait Rehabilitation Robots, Cale J. Stolle

Department of Mechanical and Materials Engineering: Dissertations, Theses, and Student Research

Gait therapy methodologies were studied and analyzed for their potential for pediatric patients. Using data from heel, metatarsal, and toe trajectories, a nominal gait trajectory was determined using Fourier transforms for each foot point. These average trajectories were used as a basis of evaluating each gait therapy mechanism. An existing gait therapy device (called ICARE) previously designed by researchers, including engineers at the University of Nebraska-Lincoln, was redesigned to accommodate pediatric patients. Unlike many existing designs, the pediatric ICARE did not over- or under-constrain the patient’s leg, allowing for repeated, comfortable, easily-adjusted gait motions. This design was assessed under clinical …

Radiation Therapy And Dosing Material Transport Methodology, Robert O'Brien

UNLV Theses, Dissertations, Professional Papers, and Capstones

A technique is examined here that utilizes high energy beta decays from a short lived radioisotope to treat medical conditions such as shallow cancerous lesions. A major benefit of beta particle interaction in tissue is a fixed penetration depth for the charged particle, with dose limited to the ultimate range of the beta particle. This method improves on some current techniques of radioactive brachytherapy, where "seeds" are placed inside patients through temporary or permanent implantation in order to kill cancerous cells or inhibit growth of tissue. The use of low energy gamma-rays is the most common method of treatment currently …

The Effects Of Cryopreservation On Human Dental Pulp-Derived Mesenchymal Stem Cells, Allison Elaine Tomlin

UNLV Theses, Dissertations, Professional Papers, and Capstones

Many studies have demonstrated clinical applications for the use of dental pulp stem cells (DPSC) for the treatment of various conditions. This has driven medical and scientific interest in the collection, isolation and banking of DPSC tissues for research into these potential therapies. Few studies to date have evaluated the viability of DPSC following long-term cryopreservation. The purpose of this study is to evaluate the effects of cryopreservation on dental pulp-derived stem cells (DPSC) viability over a period of three years. Dental pulp-derived stem cells were isolated and cultured from thirty-one healthy teeth. DPSC isolates were assessed for doubling-time and …

An Emg-Based Patient Monitoring System Using Zynq Soc Device, Farhad Fallahlalehzari

UNLV Theses, Dissertations, Professional Papers, and Capstones

This thesis describes the design, development, and testing of an EMG-based patient monitoring system using the Zynq device. Zynq is a system on chip device designed by Xilinx which consists of an ARM dual cortex-A9 processor as well as an FPGA integrated into one chip. This work also analyzes the performance of image-processing algorithms on this system and compares that performance to more traditional PC-based systems. Image processing algorithms, such as Sobel edge detection, dilation and erosion, could be used in conjunction with a camera for the patient monitoring purposes. These algorithms often perform sub-optimally on processors because of their …

Flex-Ro: Design, Implementation, And Control Of Subassemblies For An Agricultural Robotic Platform, Jared Patrick Werner

Department of Agricultural and Biological Systems Engineering: Dissertations, Theses, and Student Research

Automation technology in agriculture is growing, making agricultural robotics viable. Innovative field usable multi-purpose robotic platforms are needed for the successful progression of agricultural robotics. Furthermore, the field of agricultural robotics would benefit from a robotic platform design allowing for variable height, thus accommodating navigation throughout various crop growth stages. A variable height machine, Flex-Ro was developed to accommodate this feature. Multiple sub-assemblies were designed and implemented for Flex-Ro. An electronic control unit (ECU) enabled engine was used to power Flex-Ro. An embedded application program was developed to control engine speed using proprietary Controller Area Network (CAN) messages in conjunction …

Fluid Dynamic Factors As A Cause And Effect Of Biofilm Formation Of Staphylococcus Aureus Biofilms, Erica Sherman

Department of Mechanical and Materials Engineering: Dissertations, Theses, and Student Research

Staphylococcus aureus bacteria are able to form biofilms and distinctive tower structures that facilitate their ability to tolerate treatment and to spread within the human body. The formation of towers, which break off, get carried downstream and serve to initiate biofilms in other parts of the body are of particular interest here. It is known that flow conditions play a role in the development, dispersion and propagation of biofilms. The influence of flow on tower formation and what factors lead to tower formation is not at all understood The hypothesis being examined is that tower structures form within a specific …

Development And Implementation Of High Fidelity Human Models For The Investigation Of Blast And Non-Penetrating Projectile Impact, Candice F. Cooper

Mechanical Engineering ETDs

Military operations abroad have highlighted the effects of several types of physical traumas including traumatic brain injury and behind armor blunt trauma. While previous approaches toward understanding and mitigating trauma caused by blast or blunt impact relied upon physical testing of animal subjects, post mortem human subjects, or human tissue surrogates, recent advances in computational capability have spurred a growing area of research in computational investigations into wound injury and its mitigation. The development of high-fidelity human torso and head-neck-torso models are presented here. These models are employed in blast and non-penetrating projectile impact simulations in order to demonstrate the …

Mechanical Reliability Of Implantable Polyimide-Based Magnetic Microactuators For Biofouling Removal, Christian G. Figueroa-Espada, Qi Yang, Hyowon Lee

The Summer Undergraduate Research Fellowship (SURF) Symposium

Hydrocephalus is a neurological disorder that typically requires a long-term implantation of a shunt system to manage its symptoms. These shunt systems are notorious for their extremely high failure rate. More than 40% of all implanted shunt systems fail within the first year of implantation. On average, 85% of all hydrocephalus patients with shunt systems undergo at least two shunt-revision surgeries within 10 years of implantation. A large portion of this high failure rate can be attributed to biofouling-related obstructions and infections. Previously, we developed flexible polyimide-based magnetic microactuators to remove obstructions formed on hydrocephalus shunts. To test the long-term …

Movement And Distribution Of Bacteria Near Surfaces, Daniel A. Quinkert, Adib Ahmadzadegan, Arezoo M. Ardekani

The Summer Undergraduate Research Fellowship (SURF) Symposium

Bacteria are found everywhere in nature, including within human/animal bodies, biomedical devices, industrial equipment, oceans and lakes. They can be found in planktonic state within a bulk liquid phase or attached to surfaces with the potential to form biofilms. In this study we are interested in the movement and distribution of bacteria near surfaces. The concentrations and fluid interactions of bacteria were characterized at various distances from a surface. Psuedomonas putida F1 was observed in a suspension near a surface. Bacteria movements were visualized with an inverted microscope at 40x magnification. P. putida F1 exhibited greater density in close proximity …

Strain Energy Absorption Corresponds To Decreased Incidence Of Ventricular Fibrillation In A Commotio Cordis Model, Kayt E. Frisch, Mark S. Link, John Van Weelden

Faculty Work Comprehensive List

A healthy teenage boy is playing high school baseball, when he is struck in the chest by the ball; minutes later, his heart is experiencing ventricular fibrillation (VF) and the only way to resuscitate him is to use a defibrillator. This phenomenon, is known as Commotio Cordis (CC), and occurs as many as 20 times each year in the United States. CC most frequently occurs in sports with small balls (e.g. baseball or lacrosse) and requires a specific set of circumstances–a projectile with a certain amount of energy that impacts directly over the left ventricle of the heart during a …

Microfluidic Platform For Impedance Characterization Of Endothelial Cells Under Fluid Shear Stress., Vanessa Velasco

Electronic Theses and Dissertations

Endothelium dysfunction has been associated with many pathophysiological processes leading to cardiovascular diseases. Studying endothelium behavior is vital to understand the onset, prevention, and treatment of such diseases. Electrical impedance spectroscopy has been shown to provide a real-time in vitro evaluation of cell behavior including cell monolayer permeability. However, the majority of published work has been primarily with static cell culture models or macro-scale models that do not properly represent the physiological sizes, structures, and environmental conditions of human blood vessels. Within this dissertation, the design, fabrication, characterization, and application of a microfluidic impedance platform is presented for the in …

Biomimetic Seal Flipper Test Rig, Gordon D. Belyea, Laura Kawashiri, Dylan Rinker, Kurt Beske

Mechanical Engineering

No abstract provided.

Non-Puncturing, No Slip Thv Leaflet Gripper, Brooks Kelly, Eric Nagaoka, Johnny Phane

Mechanical Engineering

Confidential