Chemical Engineering Commons^™

การสกัดคอลลาเจนจากเศษของครีบปลาหมึกกล้วย (Loligo Duvauceli) ซึ่งเป็นของเสียในอุตสาหกรรมอาหารทะเล, ศิริพงศ์ โสมสิริวัลย์

Chulalongkorn University Theses and Dissertations (Chula ETD)

หมึกกล้วย (Indian squid) สายพันธุ์ Loligo duvauceli เป็นสัตว์ทะเลทางเศรษฐกิจที่สำคัญของประเทศไทย พบว่าครีบหมึกจัดว่าเป็นของเสียในกระบวนการผลิตจากหมึกกล้วยคิดเป็น 12% และมีราคาถูก โดยครีบหมึกกล้วยแห้งประกอบด้วยความชื้น 4.62% โปรตีน 77.08% ไขมัน 15.60% และ เถ้า 3.03% ในงานวิจัยนี้ได้สกัดคอลลาเจนจากครีบหมึกกล้วยบดโดยใช้สารละลายโซเดียมไฮดรอกไซด์ความเข้มข้น 0.5 โมลต่อลิตรเพื่อกำจัดไขมันและโปรตีนอื่นๆ จากนั้นนำไปสกัดต่อด้วยกรดแอซิติกความเข้มข้น 0.5 โมลต่อลิตรที่อุณหภูมิ 4 องศาเซลเซียส แยกส่วนของแข็งและสารละลายออกจากกันด้วยการกรอง และนำสารละลายกรดที่ได้ไปทำแห้งด้วยวิธีแช่เยือกแข็ง โดยของแข็งที่ได้จะเรียกว่า คอลลาเจนที่ละลายในกรด (ASC) ส่วน คอลลาเจนที่ละลายในเอนไซม์เปปซิน (APSC) สกัดได้โดยใช้สารละลายเปปซินปริมาณ 1% โดยน้ำหนักต่อปริมาตรในกรดแอซิติก 0.5 โมลต่อลิตร ในขั้นตอนการสกัดพบว่าผลได้ของคอลลาเจน ASC เท่ากับ 0.69 ± 0.25% และสามารถสกัดคอลลาเจน APSC ได้ 3.02 ± 00.16% เมื่อสกัดที่ 48 ชั่วโมงและ 1.42 ± 0.41% เมื่อสกัดที่ 24 ชั่วโมง ตรวจสอบน้ำหนักโมเลกุลของคอลลาเจนด้วยเทคนิค SDS-Page เทียบกับคอลลาเจนชนิดที่ 1 จากหนังหมูพบว่าคอลลาเจนที่สกัดได้จากครีบหมึกเป็นคอลลาเจนชนิด SQ ([α1]2[α2]1) ซึ่งมีลักษณะคล้ายกับคอลลาเจนชนิดที่ 1 โดย ASC ประกอบด้วยสาย α1 (202.39 kDa), α2 (159.90 kDa) และ β (281.50 kDa) และ APSC ประกอบด้วยสาย α1 (184.19 kDa), α2 (145.52 kDa) และ β (281.50 kDa) แสดงถึงส่วนเทโลเปปไทด์ถูกเอนไซม์เปปซินย่อยส่วนเทโลเปปไทด์ ฟูเรียร์ทรานส์ฟอร์มอินฟราเรดสเปกตรัมของ ASC และ …

Modeling Electrospun Fibrous Materials, Sina Hassanpouryousefi

Theses and Dissertations

Electrospinning has been the focus of countless studies for the past decades for applications, including but not limited to, filtration, tissue engineering, and catalysis. Electrospinning is a one-step process for producing nano- and/or micro-fibrous materials with diameters ranging typically from 50 to 5000 nm. The simulation algorithm presented here is based on a novel mass-spring-damper (MSD) approach devised to incorporate the mechanical properties of the fibers in predicting the formation and morphology of the electrospun fibers as they travel from the needle toward the collector, and as they deposit on the substrate. This work is the first to develop a …

Engineering Of Earth-Abundant Electrochemical Catalysts, Dylan D. Rodene

Theses and Dissertations

Alternative energy research into hydrogen production via water electrolysis addresses environmental and sustainability concerns associated with fossil fuel use. Renewable-powered electrolyzers are foreseen to produce hydrogen if energy and cost requirements are achieved. Electrocatalysts reduce the energy requirements of operating electrolyzers by lowering the reaction kinetics at the electrodes. Platinum group metals (PGMs) tend to be utilized as electrocatalysts but are not readily available and are expensive. Ni_1-xMo_x alloys, as low-cost and earth-abundant transition metal nanoparticles (NPs), are emerging as promising electrocatalyst candidates to replace expensive PGM catalysts in alkaline media. Pure-phase cubic and hexagonal Ni_{1-x …}

Online Model Predictive Control Of A Nonisothermal And Nonisobaric Membrane Reactor For Water-Gas Shift Reaction Applications, Jacob Martin Douglas

Graduate Theses, Dissertations, and Problem Reports (ETD)

Online Model Predictive Control of a Nonisothermal and Nonisobaric Membrane Reactor for Water-Gas Shift Reaction Applications Jacob M. Douglas Modern hydrogen production units are tasked with producing the most hydrogen possible while dealing with flow variations caused by changing power demands. Classical methods for hydrogen production employing the water-gas shift reaction are governed by equilibrium limitations that take effect at high temperatures and high concentrations of H2 (Georgis, et al., 2014). The implementation of a membrane reactor with temperature control enables the hydrogen concentration and temperature to reach an equilibrium at a higher concentration of H2. Another challenge that is …

Design And Implementation Of Model Predictive Control Strategies For Improved Power Plant Cycling, Xin He

Graduate Theses, Dissertations, and Problem Reports (ETD)

Design and Implementation of Model Predictive Control Strategies for Improved Power Plant Cycling

Xin He

With the increasing focus on renewable energy sources, traditional power plants such as coal-fired power plants will have to cycle their load to accommodate the penetration of renewables into the power grid. Significant overshooting and oscillatory performance may occur during cycling operations if classical feedback control strategies are employed for plantwide control. To minimize the impact when power plants are operating away from their designed conditions, model-based optimal control strategies would need to be developed for improved power plant performance during cycling.

In this thesis, …

Development Of A Dynamic Model And Control System For Load-Following Operation Of Supercritical Pulverized Coal Power Plants, Parikshit S. Sarda

Graduate Theses, Dissertations, and Problem Reports (ETD)

Thermal power plants that have been designed to operate at their rated capacity are being forced to cycle their load and operate under low-load condition to meet changing load demands due to the increased penetration of renewables into the electric grid. The rapid load-following operation is leading to challenging control problems. The goal of this research is to develop dynamic model and control system for efficient load-following operation. The focus of this work is on supercritical pulverized coal (SCPC) power plants. The steady-state model is developed using Aspen Plus and Aspen Custom Modeler and then converted to a pressure-driven Aspen …

Insights Into Well Performance And Completion Optimization Using A Coupled Fracfocus And Drillinginfo Database, Mustafa A. Al-Alwani

Doctoral Dissertations

“The hydraulic fracturing designs, drilling, and completion trends are undergoing continuous change as the oil and gas industry pushing the boundaries of the traditional designs to increase wells productivity and meet the energy demand. The lateral length in addition to the amount of proppant and water used in well stimulation have witnessed a paradigm shift over the past few years. The motivation for this work began with a desire to better understand well performance as a function of the type of fracturing fluid treatment applied. An early objective was to compare whether East Texas Cotton Valley wells stimulated with water …

Experimental Investigation Of Liquid Contact In The Developing Post-Dryout Chf Flow Boiling Regime Using Surface Mounted Thermistors, Hiralkumar Harshadbhai Patel

Doctoral Dissertations

"Understanding heat transfer in the post-critical heat flux (CHF) flow boiling regime is important for determining the performance of the heat transfer equipment for various industrial applications requiring high heat transfer rates, e.g., heat exchangers, boilers, chemical and nuclear reactors. Liquid can be present in the core of the flow channel in the form of entrained liquid droplets, especially immediately downstream of film dryout. These droplets are suspected to provide an important heat transfer mechanism as they impinge on the heated wall. The objective of the current study is to investigate liquid contact with the heated wall in this flow …

Plugging Performance Of Preformed Particle Gels In Fractures And Its Influencing Factors, Ze Wang

Doctoral Dissertations

"Preformed particle gels (PPG) has been successfully applied to combat the water channeling caused by fractures or fracture-like channels. Understanding the placement and plugging of PPG in fractures is crucial for gel treatment design. The objective of the dissertation is to explore the plugging performance of three PPG products in two types of fracture models, the partially and fully open fractures. The following studies has been conducted and conclusions have been drawn based on the results and analysis. First, the placement and plugging performance of conventional PPG was investigated using core flooding experiments conducted partially open fractures. The plugging efficiency …

Confirmation Of Data-Driven Reservoir Modeling Using Numerical Reservoir Simulation, Al Hasan Mohamed Al Haifi

Graduate Theses, Dissertations, and Problem Reports (ETD)

Data driven reservoir modeling, also known as Top-Down Model (TDM), is an alternative to the traditional numerical reservoir simulation technique. Data driven reservoir modeling is a new technology that uses artificial intelligence and machine learning to build full-field reservoir models using field measurements (data - facts) instead of mathematical formulations that represent our current understanding of the physics of the fluid flow through porous media. TDM combines all field measurements into a comprehensive reservoir model to predict the production from each well in a field with multiple wells.

There are many opinions, speculations and criticism about not using the physics-based …

New Method Of Manufacturing Carbon Foam, Matthew D. Artimez

Graduate Theses, Dissertations, and Problem Reports (ETD)

Carbon foam is a product that has some unique features. Carbon foam is a light weight material that has a high crush strength. It is electrically conductive, but because it is composed of air space between the tendrils, it is not a thermal conductor. Since it contains no volatile content, it is noncombustible. All these features allow carbon foam to have many modern applications. Currently, there are only three methods of producing carbon foam, and all three are not cost- efficient enough to meet the demand of potential new markets.

In this thesis, a new procedure of producing carbon foam …

Development Of A Sustainability Evaluation And Control Framework For Chemical Processes, Shuyun Li

Graduate Theses, Dissertations, and Problem Reports (ETD)

Industry, government, and society have begun to shift from economic stand-alone focus to the inclusion of sustainability in the decision-making process. This shift can be attributed to the growing environmental and social awareness that makes consumers and stakeholders not only care about product quality and cost, but also products and processes that minimize the environmental impact and conserve natural resources. As a result, some progress has been made in recognizing and understanding the challenges of sustainable development, which helps evaluating the sustainability performance of a specific process/product. In particular, sustainability assessment tools and methodologies have been developed to help the …

Intelligent Data-Driven Decision-Making To Mitigate Or Stop Lost Circulation, Husam Hasan Alkinani

Doctoral Dissertations

”Lost circulation is a challenging problem in the oil and gas industry. Each year, millions of dollars are spent to mitigate or stop this problem. The aim of this work is to utilize machine learning and other intelligent solutions to help to make better decision to mitigate or stop lost circulation. A detailed literature review on the applications of decision tree analysis, expected monetary value, and artificial neural networks in the oil and gas industry was provided. Data for more than 3000 wells were gathered from many sources around the world. Detailed economics and probability analyses for lost circulation treatments’ …

Characterization Of Aerosols In An Underground Mine, Arash A. Habibi

Doctoral Dissertations

“Diesel-powered engines are a common source of submicron carbon-rich particles. Characterizing morphological and physical attributes of diesel agglomerates is therefore of great importance to be able to identify the source and improve removal technology. Size-segregated sampling was conducted in two phases of underground experiments. Scanning transmission electron microscopy and fast mobility particle sizers were used to determine the size distribution of agglomerates based on particle mobility and projected area diameter. Controlled zone sampling test results were used to determine the morphological characteristics of agglomerates for specific types of diesel equipment both with and without removal strategies. Changes in fractal dimension, …

Plenum-To-Plenum Heat Transfer Characteristics Under Natural Circulation In A Scaled-Down Prismatic Modular Reactor, Salman Mohammed Alshehri

Doctoral Dissertations

“Gas-cooled reactor (GCR) is being developed under the Next Generation Nuclear Plant Program (NGNP) in nuclear engineering studies. As the world searches for an energy source with high energy density, clean, abundant, and storable nature to avoid global warming issues, GCR seems to be a promising solution, particularly the possibility of producing hydrogen. Studying and developing the safety analysis and GCR technologies are required for the optimum design and safety of GCR system. Multiphase Reactors Engineering and Applications Laboratory (mReal) at Missouri University of Science and Technology (S&T) has developed a natural convection heat transfer test facility with one riser …

Computational Fluid Dynamics Modeling And Comparison Of Advanced Techniques For Heat Transfer Augmentation For Nuclear Applications, Salman Mohammed Alzahrani

Doctoral Dissertations

“Passive safety is the most important feature of NuScale’s reactor designs. Twist tape is one passive heat enhance heat technique. The present research investigated thermo-hydraulic characteristics of natural and forced convection of water under different configurations of twisted tape inserted in tube as well as NuScale rod bundles for uniform wall heat flux using computational fluid dynamics (CFD) using ANSYS Fluent 18.1. Results for twist tape inserted in tube under natural circulation showed that heat transfer enhanced and pressure drop increased to 28% and 102.8% over the plain tube respectively. Regularly spaced tapes, and different widths of the twisted tapes …

Transient Multiphase Flow Simulation For Unloading Of Frac Hit Gas Wells, Miguel Angel Cedeno Moreno

Doctoral Dissertations

"This work seeks to develop a fully step-by-step transient multiphase flow simulation valid for unloading gas wells using nitrogen. It studies the behavior of nitrogen for unloading horizontal gas wells with gas injection in the annulus. The work investigates unloading non-Newtonian fluids such as those which invade offset wells when a frac hit occurs during hydraulic fracturing operations in unconventional wells. The effect of varying tubing depth and injection pressure are included in the study.

Results show that as the plastic viscosity increases, the nitrogen volume and time to unload will be increased. As tubing depth increases, the nitrogen volume …

The Effects Of Low Aspect Ratio And Heat Exchanging Internals On The Bubble Properties And Flow Regime In A Pilot-Plant Bubble/Slurry Bubble Column For Fischer-Tropsch Synthesis, Hayder Al-Naseri

Doctoral Dissertations

"Fischer-Tropsch synthesis (F-T) is a process utilized to convert the syngas mixture of CO and H₂ to synthetic fuel and chemicals that executed commercially by using the bubble/slurry bubble column reactor. The experimental results reveal that the investigated parameters, in terms the presence of internals, and reducing the aspect ratio and the solids loading, increase the local gas holdup, interfacial area, bubble passage frequency, and decrease the bubble rise velocity, bubble chord length. Meanwhile, the aspect ratio H/D = 4, and 5 provide enough height to established the fully developed flow regime. As a result of the variation in …

Modeling And Simulation Of Micro/Nano-Rod Distribution In Micro Channel Flows, Saman Monjezi

Doctoral Dissertations

"The behavior of a typical nanorod particle in microscale flows was theoretically investigated, considering the effect of the wall on the rotational and translation motions of the non-spherical particle. Initially, a systematic method using Brownian dynamics simulation of the rotational motion of nanorod was performed to obtain the average orientation distribution of a nanorod in various range of Peclet number and position from the confining wall. Subsequently, the results of the angle distributions simulation were employed to generate a universal mathematical model for the particle orientation distribution, which our model of concentration distribution of high aspect ratio nanorods in the …

Building Shared Knowledge For Eor Technologies: Screening Guideline Constructions, Dashboards, And Advanced Data Analysis, Na Zhang

Doctoral Dissertations

"Successful implementation of enhanced oil recovery (EOR) technology requires comprehensive knowledge and experiences based on existing EOR projects. EOR screening guidelines and EOR reservoir analog are served as such knowledge which are considered as the first step for a reservoir engineer to determine the next step techniques to improve the ultimate oil recovery from their assets. The objective of this research work is to provide better assistance for EOR selection by using fundamental statistics methods and machine learning techniques.

In this dissertation, a total of 977 worldwide EOR projects with the most uniformed, high-quality, and comprehensive information were collected from …