Identification Of Ecg Anomalies Through Deep Deterministic Learning,
2020
Universiti Malaya
Identification Of Ecg Anomalies Through Deep Deterministic Learning, Uzair Iqbal
Student Works (2020-2029)
Electrocardiography (ECG) is a primary diagnostic tool for measuring the malfunctioning of the heart muscles in the context of morbidity of different cardiac diseases and arrhythmia. Different existing techniques and methods delivered accurate cardiac diseases myocardial infarction (heart stroke) and atrial fibrillation recognition. However, there are still some flaws in existing methods like recognition of special myocardial infarction situation flattened T wave in “Non-Specific ST-T Changes (nsst-t)” and reduction of computational cost in cardiac diseases recognition. Accurate recognition of cardiac diseases along with least computational complexity and feature analysis of flattened T wave in myocardial infarction remains an open job. …
Incorporation Of Lignin In Natural And Synthetic Biomaterials To Alter Mechanical And Biochemical Properties For Enhanced Wound Healing,
2020
Louisiana State University and Agricultural and Mechanical College
Incorporation Of Lignin In Natural And Synthetic Biomaterials To Alter Mechanical And Biochemical Properties For Enhanced Wound Healing, Jorge Alfonso Belgodere
LSU Doctoral Dissertations
It is estimated that chronic, non-healing wounds affect more than 6.5 million Americans annually, with an estimated healthcare cost beyond $14 billion. Here, we attempted to create composites of natural (collagen type I or gelatin-methacrylate) or synthetic (poly(ethylene glycol) polymers incorporating a natural plant component, lignin, to combat the costs and limitations current wound healing methods face. Three-dimensional matrices of collagen type I (Col I) are widely used in tissue engineering applications for its abundance in many tissues, bioactivity with many cell types, and excellent biocompatibility. Inspired by the structural role of lignin in plant tissue, we found that sodium …
Update On The Use Of Transcranial Electrical Brain Stimulation To Manage Acute And Chronic Covid-19 Symptoms,
2020
NYU Langone Health
Update On The Use Of Transcranial Electrical Brain Stimulation To Manage Acute And Chronic Covid-19 Symptoms, Giuseppina Pilloni, Marom Bikson, Bashar W. Badran, Mark S. George, Steven A. Kautz, Alexandre Hideki Okano, Abrahão Fontes Baptista, Leigh E. Charvet
Publications and Research
The coronavirus disease 19 (COVID-19) pandemic has resulted in the urgent need to develop and deploy treatment approaches that can minimize mortality and morbidity. As infection, resulting illness, and the often prolonged recovery period continue to be characterized, therapeutic roles for transcranial electrical stimulation (tES) have emerged as promising non-pharmacological interventions. tES techniques have established therapeutic potential for managing a range of conditions relevant to COVID-19 illness and recovery, and may further be relevant for the general management of increased mental health problems during this time. Furthermore, these tES techniques can be inexpensive, portable, and allow for trained self-administration. Here, …
Real-Time Optical Monitoring Of Endotracheal Tube Displacement,
2020
Marquette University
Real-Time Optical Monitoring Of Endotracheal Tube Displacement, Ramzan Ullah, Karl Doerfer, Pawjai Khampang, Faraneh Fathi, Wenzhou Hong, Joseph E. Kerschner, Bing Yu
Biomedical Engineering Faculty Research and Publications
Proper ventilation of a patient with an endotracheal tube (ETT) requires proper placement of the ETT. We present a sensitive, noninvasive, operator-free, and cost-effective optical sensor, called Opt-ETT, for the real-time assessment of ETT placement and alerting of the clinical care team should the ETT become displaced. The Opt-ETT uses a side-firing optical fiber, a near-infrared light-emitting diode, two photodetectors with an integrated amplifier, an Arduino board, and a computer loaded with a custom LabVIEW program to monitor the position of the endotracheal tube inside the windpipe. The Opt-ETT generates a visual and audible warning if the tube moves over …
Opto-Fluidic Manipulation Of Microparticles And Related Applications,
2020
University of South Florida
Opto-Fluidic Manipulation Of Microparticles And Related Applications, Hao Wang
USF Tampa Graduate Theses and Dissertations
Contemporary biomedical technologies introduce many new instruments that are important for diagnosis and treatment of the patients. Instrument that can do rapid detection of bacterial infections, and further direct medical practitioner to prescribe optimal antibiotics is highly desirable. But unfortunately, this instrument is not available yet. Ideally, this instrument has to be portable to be used at point-of-care. This means it has to be small and inexpensive, but still highly accurate. Another critical requirement for the instrument is that the test results have to be available promptly. Because in case of such complications of bacterial infections as sepsis, each additional …
Fuzzy Logic Based Control For Membrane Oxygenator In Blood Purification Process,
2020
Universiti Malaya
Fuzzy Logic Based Control For Membrane Oxygenator In Blood Purification Process, Hany Hazfiza Manap
Student Works (2020-2029)
Membrane oxygenator in Extracorporeal Life Support (ECLS) is commonly used as a main component in Cardiopulmonary Bypass (CPB), Extracorporeal Membrane Oxygenator (ECMO) and Extracorporeal Carbon Dioxide Removal (ECCO2R). In this study, the focus is on Carbon Dioxide (CO2) gas exchange process in membrane oxygenator, which the CO2 is automatically controlled by adjusting sweep gas flow rate that entering the membrane oxygenator in achieving the desired pCO2 required by the particular patients. This automatic control action is controlled by the implementation of three controllers, Proportional-IntegralDerivative (PID) that is tuned by Ziegler-Nichols continuous cycling method, Fuzzy Logic Controller (FLC) and Fuzzy-PID controllers. …
Urine Volume Reduction During Long-Duration Cave Exploration By A Light-Weight And Portable Forward Osmosis System,
2020
University of Akron
Urine Volume Reduction During Long-Duration Cave Exploration By A Light-Weight And Portable Forward Osmosis System, Sebastian Engelhardt, Katey E. Bender, Jörg Vogel, Stephen E. Duirk, Francisco B. Moore, Hazel A. Barton
International Journal of Speleology
The preservation of caves is a challenge during long-duration cave expeditions where human waste can add significant nitrogen to the cave ecosystem. Since the removal of urine that accumulates during a multi-day caving trip is not always feasible due to weight and volume constraints, a light-weight and portable filtration system that is capable of reducing urine volume would be desirable. In this study we tested the Aquaporin Inside hollow fiber membrane in a forward osmosis (FO) setup to evaluate its capability to reduce urine volume while rejecting nitrogenous compounds using different draw solution chemistries and water recovery rates. As a …
Fabrication And Characterisation Of Highly Aligned Fibrous Assemblies,
2020
Universiti Malaya
Fabrication And Characterisation Of Highly Aligned Fibrous Assemblies, Tan Chin Joo
Student Works (2020-2029)
Vascular grafting has been an effective remedy to vascular diseases for decades. Autografting by using the veins or arteries in the patient’s body is found to have patency rate for years. However, autografting may not be possible when compatible vessels are not available. In this case, synthetic vascular grafts are found to be effective replacements. Nevertheless, synthetic grafts with diameter less than 4 mm becomes challenging due to thrombogenicity and mismatch of mechanical properties with the native vessels. Along this line, the ability to develop new biostable synthetic materials suitable for smaller grafts and the ability to evaluate their resulting …
Effectiveness Of Building Systems Strategies For Mitigation Of Airborne Transmission Of Sars-Cov-2,
2020
Syracuse University
Effectiveness Of Building Systems Strategies For Mitigation Of Airborne Transmission Of Sars-Cov-2, Meng Kong, Jialei Shen, Bing Dong, Jianshun Jensen Zhang
Mechanical and Aerospace Engineering - All Scholarship
Airborne transmission has been recognized as a major transmission pathway for the infectious disease COVID-19. This study investigated the effectiveness of several indoor air quality (IAQ) control strategies on the mitigation of airborne transmission of SARS-CoV-2, the virus that causes COVID-19. The well-known airborne disease infection risk model (Wells-Riley equation) was used to estimate the infection risk of the SARS-CoV-2 in seven (7) different types of spaces including conference center/ballrooms, hotel bistro//cafeteria, hotel lobby, classrooms (lecture), conference room/small classroom, hotel or cruise ship guest rooms and open plan offices. The IAQ control strategies included increased ventilation rate, improved air distribution …
An Exercise Device Used To Achieve Bone Formation Metrics For The Strengthening Of The Proximal Femur.,
2020
University of Louisville
An Exercise Device Used To Achieve Bone Formation Metrics For The Strengthening Of The Proximal Femur., Sean P. Coyle
Electronic Theses and Dissertations
Lateral falls often lead to hip fracture particularly in the elderly who have low bone mineral density. These fractures frequently lead to indirect mortality soon after injury. Normal use over the course over a lifetime leads to optimized adaptation of the bone in the proximal femur according to normal loading. A lateral fall generates non-normal, lateral loading at the proximal hip where the bone has not adapted to withstand such loading. The resulting fracture is generated by reversed strains on the bone tissue in the femoral neck in the hip in contrast to vertical, quotidian loading. Modern practices for preventing …
Modulation Of Ros In Nanosecond-Pulsed Plasma-Activated Media For Dosage-Dependent Cancer Cell Inactivation In Vitro,
2020
Old Dominion University
Modulation Of Ros In Nanosecond-Pulsed Plasma-Activated Media For Dosage-Dependent Cancer Cell Inactivation In Vitro, Chunqi Jiang, Esin Bengisu Sozer, Shutong Song, Nicola Lai, P. Thomas Vernier, Sigi Guo
Bioelectrics Publications
Dosage control of reactive oxygen and nitrogen species (RONS) is critical to low-temperature plasma applications in cancer therapy. Production of RONS by atmospheric pressure, nonequilibrium plasmas in contact with liquid may be modulated via plasma conditions including plasma treatment time and pulse voltage and repetition frequency. In this study, a terephthalic acid-based probe was used to measure hydroxyl radicals [OHaq] in water exposed to plasma and to demonstrate that the OHag concentration increases linearly with treatment time. Fluorometric measurements of hydrogen peroxide concentration in plasma-activated water show a linear relationship between the H2O2 production …
Topology And Control Of Self-Assembled Domain Patterns In Low-Dimensional Ferroelectrics,
2020
University of Arkansas, Fayetteville
Topology And Control Of Self-Assembled Domain Patterns In Low-Dimensional Ferroelectrics, Y. Nahas, S. Prohorenko, Q. Zhang, V. Govinden, N. Valanoor, L. Bellaiche
Physics Faculty Publications and Presentations
Whilst often discussed as non-trivial phases of low-dimensional ferroelectrics, modulated polar phases such as the dipolar maze and the nano-bubble state have been appraised as essentially distinct. Here we emphasize their topological nature and show that these self-patterned polar states, but also additional mesophases such as the disconnected labyrinthine phase and the mixed bimeron-skyrmion phase, can be fathomed in their plurality through the unifying canvas of phase separation kinetics. Under compressive strain, varying the control parameter, i.e., the external electric field, conditions the nonequilibrium self-assembly of domains, and bridges nucleation and spinodal decomposition via the sequential onset of topological transitions. …
Calcium Sulfate-Containing Glass Polyalkenoate Cement For Revision Total Knee Arthroplasty Fixation,
2020
Missouri University of Science and technology
Calcium Sulfate-Containing Glass Polyalkenoate Cement For Revision Total Knee Arthroplasty Fixation, Leyla Hasandoost, Adel Alhalawani, Omar Rodriguez, Alireza Rahimnejad Yazdi, Paul Zalzal, Emil H. Schemitsch, Stephen D. Waldman, Marcello Papini, Mark R. Towler
Chemical and Biochemical Engineering Faculty Research & Creative Works
Poly (methyl methacrylate) (PMMA) bone cement is used as a minor void filler in revision total knee arthroplasty (rTKA). The application of PMMA is indicated only for peripheral bone defects with less than 5 mm depth and that cover less than 50% of the bone surface. Treating bone defects with PMMA results in complications as a result of volumetric shrinkage, bone necrosis, and aseptic loosening. These concerns have driven the development of alternative bone cements. We report here on novel modified glass polyalkenoate cements (mGPCs) containing 1, 5 and 15 wt% calcium sulfate (CaSO4) and how the modified …
Wetting-Driven Formation Of Present-Day Loess Structure,
2020
Taiyuan University of Technology
Wetting-Driven Formation Of Present-Day Loess Structure, Yanrong Li, Weiwei Zhang, Shengdi He, Adnan Aydin
Faculty and Student Publications
© 2020 The Authors Present-day loess, especially Malan loess formed in Later Quaternary, has a characteristic structure composed of vertically aligned strong units and weak segments. Hypotheses describing how this structure forms inside original loess deposits commonly relate it to wetting-drying process. We tested this causal relationship by conducting unique experiments on synthetic samples of initial loess deposits fabricated by free-fall of loess particles. These samples were subjected to a wetting-drying cycle, and their structural evolutions were documented by close-up photography and CT scanning. Analysis of these records revealed three key stages of structural evolution: initiation (evenly distributed cracks appear …
Effects Of Marathon Training On Male And Female Femoral Stress Fracture Risk,
2020
California Polytechnic State University, San Luis Obispo
Effects Of Marathon Training On Male And Female Femoral Stress Fracture Risk, Clara Lin
Master's Theses
Marathon runners are prone to femoral stress fractures due to the high magnitudes and frequencies of lower extremity loads during training. Female runners tend to have a greater incidence of stress fracture compared to male runners. Sex-specific differences in body structure, joint pressure, and muscle activation patterns that influence bone remodeling may cause this observed difference in stress fracture occurrence. The goal of this thesis was to develop a finite element model of the femur during marathon training, then determine if marathon training affected bone properties of male and female runners differently. To achieve this goal, a finite element femur …
Biomechanical And Biophysical Properties Of Breast Cancer Cells Under Varying Glycemic Regimens,
2020
Old Dominion University
Biomechanical And Biophysical Properties Of Breast Cancer Cells Under Varying Glycemic Regimens, Diganta Dutta, Xavier-Lewis Palmer, Jose Ortega-Rodas, Vasundhara Balraj, Indrani Ghosh Dastider, Surabhi Chandra
Electrical & Computer Engineering Faculty Publications
Diabetes accelerates cancer cell proliferation and metastasis, particularly for cancers of the pancreas, liver, breast, colon, and skin. While pathways linking the 2 disease conditions have been explored extensively, there is a lack of information on whether there could be cytoarchitectural changes induced by glucose which predispose cancer cells to aggressive phenotypes. It was thus hypothesized that exposure to diabetes/high glucose alters the biomechanical and biophysical properties of cancer cells more than the normal cells, which aids in advancing the cancer. For this study, atomic force microscopy indentation was used through microscale probing of multiple human breast cancer cells (MCF-7, …
Characterizing The Biophysical Properties And Origin Of Extracellular Matrix In The Breast Tumor Microenvironment,
2020
Louisiana State University and Agricultural and Mechanical College
Characterizing The Biophysical Properties And Origin Of Extracellular Matrix In The Breast Tumor Microenvironment, Connor T. King
LSU Master's Theses
Tumors derived from breast tissue possess the ability to manipulate and permanently alter their surrounding tissue. Studies demonstrate that tissues surrounding breast tumors have differences in secreted factors as well as extracellular matrix (ECM) deposition and structure. However, some fundamental gaps exist within this paradigm: specifically, what exacerbates this transformation and are these changes maintained between the subtypes of breast tumors? Therefore, a targeted evaluation of the effects of the tumor on the stromal microenvironment in a subtype specific manner will be invaluable. To determine if tumor aggressiveness and subtype differentially regulate the tumor microenvironment, a model must be constructed …
Convergence Of Auditory Nerve Fibers Onto Globular Bushy Cells,
2020
University of South Florida
Convergence Of Auditory Nerve Fibers Onto Globular Bushy Cells, Matthew Kersting
USF Tampa Graduate Theses and Dissertations
Globular bushy cells (GBCs) of the cochlear nucleus are specialized neurons that encode the temporal features of sound. Multiple auditory nerve inputs are known to synapse onto a single GBC, but the exact number and sizes of these inputs have not been systematically investigated in adult mice. To gain a high-resolution and unbiased look at the auditory inputs contacting GBCs, our lab utilized Serial Block-Face Scanning Electron Microscopy. Specifically, 21 GBCs and all their large inputs were reconstructed at nanometer resolution. To produce the most precise results, we applied careful attention to the reconstruction and implemented cutting-edge meshing algorithms. We …
Analysis Of Glutathione Supplementation Effects On Female Metabolic Syndrome Condition Using Classification Techniques,
2020
Universiti Malaya
Analysis Of Glutathione Supplementation Effects On Female Metabolic Syndrome Condition Using Classification Techniques, Nur Rasyidah Hasan Basri
Student Works (2020-2029)
Lesser known to the public that main antioxidants in our body, Glutathione are also said to influence the metabolic syndrome (MS) condition. Oral supplementation consisting of glutathione precursors and vitamin C introduced in the study was to improve glutathione (GSH) status of the consumer and the main objective of this study is to investigate GSH effects on selected MS condition. Several known studies had proven that oral supplementation improved GSH level of consumer. However, there is no definite proof on how it’s affecting MS parameters. Also, there is less study carried out on the relationship between glutathione levels and metabolic …
In The Pursuit Of Assistance: A Team's Desire To Not Let A Congenital Amputation Get In A Young Boy's Way,
2020
Purdue University
In The Pursuit Of Assistance: A Team's Desire To Not Let A Congenital Amputation Get In A Young Boy's Way, Carl Russell Iii, Gavin Loucks, Kirsten Wozniak
Purdue Journal of Service-Learning and International Engagement
EPICS is a service-learning design program run through Purdue University. It strives to teach students design skills through providing for individuals, communities, and organizations in the surrounding area while mirroring engineering industry standards. BME (Biomedical Engineering) is a team within EPICS that strives to serve community partners through biomedical applications. William Sevick is an elementary school student with a congenital arm amputation. William and his family have been working with the BME team for the past three years designing assistive devices with the purpose of improving his actions in daily life such as eating, playing games, and riding his bike.
