Multiphysics Computational Model Of Fluid Flow And Mass Transport In Aneurysm,
2020
Duquesne University
Multiphysics Computational Model Of Fluid Flow And Mass Transport In Aneurysm, Tanja Cupac
Electronic Theses and Dissertations
The abdominal aortic aneurysm is progressive, asymptomatic, and can eventually lead to rupture which is a catastrophic event leading to massive internal bleeding and possibly death. AAA cases have been characterized by the development of an intraluminal thrombus (ILT). The ILT correlates with the progression of hypoxia in the arterial wall. The extent that ILT presence reduces oxygen flux to the wall has not been quantified and there is rather a poor understanding of key parameters that can affect thrombus-mediated oxygen transport in AAA. The purpose of this study is to address this gap and to assess the effects of …
Biomechanical Investigation Of Individual With Over-Pronation And Over-Supination Foot During Walking,
2020
Universiti Malaya
Biomechanical Investigation Of Individual With Over-Pronation And Over-Supination Foot During Walking, Ghani Nur Saibah
Student Works (2020-2029)
Over-pronation and over-supination foot conditions are foot deformity that can lead to unstable ankle and subtalar joint during walking. They are define as condition where the foot roll in and out excessively from its neutral line and can lead to misalignment of the foot and leg in human in which can create abnormal gait cycle. Therefore, the purposes of this study are to analyze the foot-ankle joint biomechanical behavior including the range of motion, joint moment, joint power and GRF in a complete gait cycle for all subjects in this study and to compare the foot-ankle biomechanical behavior between normal …
Do Different Pathologies Affect The Relationship Between The Stiffness Of The Plantar Fascia And The Function Of The Mtp Joint?,
2020
Old Dominion University
Do Different Pathologies Affect The Relationship Between The Stiffness Of The Plantar Fascia And The Function Of The Mtp Joint?, Madeline Ryan Pauley
Biomedical Engineering Theses & Dissertations
Compared to healthy individuals, individuals with plantar fasciitis and diabetes experience material and structural property changes to soft tissues in the feet. The purpose of this study was to compare the relationship between material properties, power absorption, and energy storage characteristics to metatarsal power between healthy, plantar fasciitis symptomatic and asymptomatic, and diabetic participants. Investigating material change differences as well as energy storage and transfer trends in different pathology groups can lead to a better overall understanding of power transfer at the metatarsophalangeal joint (MTP). Participants were recruited for kinematic gait analysis and lower extremity shear wave elastography analysis and …
Utilizing Neural Networks And Wearables To Quantify Hip Joint Angles And Moments During Walking And Stair Ascent,
2020
Dartmouth College
Utilizing Neural Networks And Wearables To Quantify Hip Joint Angles And Moments During Walking And Stair Ascent, Megan V. Mccabe
ENGS 88 Honors Thesis (AB Students)
Wearable sensors were leveraged to develop two methods for computing hip joint angles and moments during walking and stair ascent that are more portable than the gold standard. The Insole-Standard (I-S) approach replaced force plates with force-measuring insoles and achieved results that match the curvature of results from similar studies. Peaks in I-S kinetic results are high due to error induced by applying the ground reaction force to the talus. The Wearable-ANN (W-A) approach combines wearables with artificial neural networks to compute the same results. Compared against the I-S, the W-A approach performs well (average rRMSE = 18%, R2 …
Smartphone-Tape Method For Calculating Body Segment Inertial Parameters For Analysis Of Pitching Arm Kinetics,
2020
California Polytechnic State University, San Luis Obispo
Smartphone-Tape Method For Calculating Body Segment Inertial Parameters For Analysis Of Pitching Arm Kinetics, Jay Sterner
Master's Theses
The objectives of this study were to (1) develop a non-invasive method (referred to as Smart Photo-Tape) to calculate participant-specific upper arm, forearm, and hand segment inertial properties (SIPs) (e.g. mass, center of mass, and radii of gyration) and (2) use those Smart Photo-Tape properties in inverse dynamics (ID) analyses to calculate injury-related pitching arm kinetics. Five 20- to 23- year-old baseball pitchers were photographed holding a baseball and analyzed using the Smart Photo-Tape method to obtain 3-D inertial properties for their upper arm, forearm, and hand. The upper arm and forearm segments were modelled as stacked elliptic cylinders and …
Design Of Prototype Prosthesis For A Canine With A Right Front Limb Deformity As An Alternate Approach To Stabilize Gait And Withstand Gait Forces,
2020
California Polytechnic State University, San Luis Obispo
Design Of Prototype Prosthesis For A Canine With A Right Front Limb Deformity As An Alternate Approach To Stabilize Gait And Withstand Gait Forces, Tayler R. Kastlunger
Master's Theses
Congenital and developmental limb deformities in canines are rare and can occur as a genetic disorder or be caused by extrinsic factors. Without surgery to correct the deformity, conservative management can be implemented to manage exercise and restrict high-intensity activity of the canine. However, any alteration to the normal gait and locomotive biomechanics of a canine can have significant long-term effects on the musculoskeletal health and quality of life of the canine. To improve quality of life and provide an alternative and more cost-effective approach to surgery, a custom prosthetic was designed and developed for a canine born with a …
Design Of A 3d Printed Bioreactor For Bone Cancer Research,
2020
South Dakota State University
Design Of A 3d Printed Bioreactor For Bone Cancer Research, Brooklyn K. Vanderwolde, Katelyn Hillson
The Journal of Undergraduate Research
Bone cancer is an aggressive disease and has peak occurrence during physiological stimulation of growth and aging. Astronauts who undergo long-term space missions also acquire an increased risk of bone tissue degeneration and cancer. Few in-vitro models currently exist capable of reproducing the complex microenvironment of bone tissue to support multicellular activity in a three-dimensional structure. This limits the ability to understand disease progression and develop suitable treatment strategies. Therefore, developing a bone tissue model and an associated bioreactor is critical to understand the risks associated with cancer progression and improve treatment and preventions related to those risks. The goal …
Development Of A Matlab Gui To Assist The Active Comprehension Of Biomedical Transport Phenomena Using A Visual Aid,
2020
University of Arkansas, Fayetteville
Development Of A Matlab Gui To Assist The Active Comprehension Of Biomedical Transport Phenomena Using A Visual Aid, Pranav Suri
Biomedical Engineering Undergraduate Honors Theses
Studies show that inductive teaching methods for Biomedical Transport Phenomena greatly benefit from an accompanying visual aid. The following project aimed to develop a MATLAB GUI application that illustrates steady-state heat transfer with a graph and heat map using user-defined boundary conditions and numerical parameters. The application was evaluated using a survey that first familiarized the user with the GUI by running through heat transfer exercises, then allowed the user to experiment with the application, and finally asked users about their experiences using a questionnaire. The responses indicate that the GUI was received positively overall, and that a MATLAB component …
The Response Of Astrocytes To Mechanical Stimuli,
2020
University of Arkansas, Fayetteville
The Response Of Astrocytes To Mechanical Stimuli, Courtney Bahan
Biomedical Engineering Undergraduate Honors Theses
Traumatic brain injuries are a common cause of injury and result from a blow to the head whether it be blunt, penetrating, or inertial. TBIs are typically obtained in a fall, while playing a sport, or in a car crash. TBIs can be diagnosed as mild (commonly referred to as a concussion), moderate, or severe based upon their score from the Glasgow coma scale. TBIs can also lead to other risks such as epilepsy or Alzheimer’s Disease as well as increasing the risk of suffering another TBI. Astrocytes are heterogeneous glial cells in the brain that alter their response based …
Redesign And Quantitative Assessment Of An Accelerated Venous Valve Fatigue Apparatus,
2020
University of Arkansas, Fayetteville
Redesign And Quantitative Assessment Of An Accelerated Venous Valve Fatigue Apparatus, Megan Kueh
Biomedical Engineering Undergraduate Honors Theses
Chronic venous insufficiency (CVI) is a form of cardiovascular disease that is caused when valves in the leg become incompetent. Current treatment methods serve to manage symptoms, but there are currently no ways to treat the underlying cause of CVI. A venous valve prosthetic made from a xenograft of a bovine jugular vein is one possible treatment method currently in the research phase. Prosthetic valves must be tested with an accelerated wear tester prior to approval for clinical testing. Although such testers exist for heart valves, physiological differences between heart and venous valves restrict the use those testers on venous …
Evaluating The Effects Of Muscle Force Production Strategies And Anterior Cruciate Ligament Forces (Strain) On Gait Patterns During Running,
2020
University of Connecticut
Evaluating The Effects Of Muscle Force Production Strategies And Anterior Cruciate Ligament Forces (Strain) On Gait Patterns During Running, Amanda Astrologo
Honors Scholar Theses
Anterior cruciate ligament (ACL) injuries are among the most common injuries experienced by athletes in the United States. Even after reconstruction surgery individuals have been known to develop complications much later in life, including long-term or permanent alterations to their gait, which may lead to early-onset knee osteoarthritis. This thesis work sought to define these alterations as they pertain specifically to running. Using results and parameters from previous studies, the goal of this study is to compare muscle force production strategies, as they relate to ACL force and strain, of injured and non-injured individuals. These values, muscle forces and ACL …
Mechanical Analysis Of In Vitro Tbi Models,
2020
University of Connecticut
Mechanical Analysis Of In Vitro Tbi Models, Dana Hamed
Honors Scholar Theses
This work details the damage done to cells when mechanically hit. The goal was to mechanically analyze in vitro traumatic brain injury (TBI) models. Parts were designed in SolidWorks to create the machine that is used to induce this damage on the cells. A force applicator that uses a 3D-printed micro-hammer to apply force on the brain cells that are being tested was created. Mechanical trauma experimentation was performed with the force applicator, while a high-speed camera recorded the damage, in order to analyze TBI models. Displacement along the scaffold can be tracked from multiple video frames. With these results, …
Multiphysics Computational Model Of Fluid Flow And Mass Transfer In Aneurysm,
2020
Duquesne University
Multiphysics Computational Model Of Fluid Flow And Mass Transfer In Aneurysm, Tanja Cupac
Graduate Student Research Symposium
The abdominal aortic aneurysm (AAA) mostly affects men between the ages 65-85 and is very common with more than 3 million cases in the United States per year. AAA is defined as the weakening of the arterial wall producing a blood-filled bulge in the body’s largest blood vessel. AAA is progressive, asymptomatic, and can eventually lead to rupture which is a catastrophic event leading to massive internal bleeding and possibly death. Of the males within this age range, 1-3% will die from this disease. About 75% of AAA cases will be characterized by the development of an intraluminal thrombus (ILT). …
The Natural Historian’S Guide To The Ct Galaxy: Step-By-Step Instructions For Preparing And Analyzing Computed Tomographic (Ct) Data Using Cross-Platform, Open Access Software,
2020
Oregon State University
The Natural Historian’S Guide To The Ct Galaxy: Step-By-Step Instructions For Preparing And Analyzing Computed Tomographic (Ct) Data Using Cross-Platform, Open Access Software, T. J. Buser, O. F. Boyd, A. Cortés, Cassandra M. Donatelli, M. A. Kolmann, J. L. Luparell, J. A. Pfeiffenberger, B. L. Sidlauskas, A. P. Summers
Engineering Faculty Articles and Research
The decreasing cost of acquiring computed tomographic (CT) data has fueled a global effort to digitize the anatomy of museum specimens. This effort has produced a wealth of open access digital three-dimensional (3D) models of anatomy available to anyone with access to the Internet. The potential applications of these data are broad, ranging from 3D printing for purely educational purposes to the development of highly advanced biomechanical models of anatomical structures. However, while virtually anyone can access these digital data, relatively few have the training to easily derive a desirable product (e.g., a 3D visualization of an anatomical structure) from …
Walking Kinematics In Young Children With Limb Loss Using Early Versus Traditional Prosthetic Knee Prescription Protocols,
2020
Kennesaw State University
Walking Kinematics In Young Children With Limb Loss Using Early Versus Traditional Prosthetic Knee Prescription Protocols, Mark Daniel Geil, Zahra Safaeepour, Brian Giavedoni, Colleen Coulter
Faculty Articles
The traditional treatment protocol for young children with congenital or acquired amputations at or proximal to the knee prescribes a prosthesis without a working knee joint, based in part on the assumption that a child learning to walk cannot properly utilize a passively flexing prosthetic knee component. An alternative to this Traditional Knee (TK) protocol is an “Early Knee” (EK) protocol, which prescribes an articulating prosthetic knee in the child’s first prosthesis, during development of crawling and transitioning into and out of upright positions. To date, no study has compared samples of children with limb loss at or proximal to …
Autocorrelation And Probability Distributions In Gait-Metronome Synchronization,
2020
University of Nebraska at Omaha
Autocorrelation And Probability Distributions In Gait-Metronome Synchronization, Charles Sloan
UNO Student Research and Creative Activity Fair
Recent research has shown that the structure of different pacing signals influences gait dynamics during coordination to those signals. Those studies, however, have not looked at the impact that probability distribution functions play in influencing our gait. This study looks at how both autocorrelation functions and probability distribution has in noisy metronomes to look for sources of synchronization. 10 healthy subjects volunteered to complete this study. The participants were required to wear custom-built glasses with a small screen projected on the lens. The screen showed a visual stimulus that correlated with various signals. The results of the study suggest that …
Effects Of Novel Tool Use: Cortical And Functional Measures In Children Using A Prosthetic Simulator,
2020
University of Nebraska at Omaha
Effects Of Novel Tool Use: Cortical And Functional Measures In Children Using A Prosthetic Simulator, Chris Copeland
UNO Student Research and Creative Activity Fair
As of 2005, there were a total of 1.6 million people living with the loss of a limb, with this population projected to double to 3.6 million by 2050 [1]. While prostheses aim to enhance the function of these individuals, it is estimated that 45% of pediatric prosthetic users reject their prosthesis [2]. The literature which describes the neurological control mechanisms of prosthetic use is sparse and often low-powered due to an inadequate number of participants. However, prosthetic simulators may be a solution to chronically low-powered prosthetic-centric studies by serving as functional homologues, though this has yet to be tested. …
Solostand,
2020
California Polytechnic State University, San Luis Obispo
Solostand, Hau Nhat Doan, Sydney Gray, Celina Dioso
Biomedical Engineering
The purpose of this scope of work is to highlight the progress and development of SoloStand sponsored by Derek Herrera, chief technical officer and founder of SpinalSingularity. SoloStand is an attachment to a wheelchair that will benefit paraplegics that use wheelchairs. A portable and customizable attachment to a wheelchair will allow the user to do everyday tasks without transferring into a separate standing wheelchair and travel more easily. This document outlines everything that has been done in fulfillment of our senior project requirements.
Cumulative Shear In Vitro Model,
2020
California Polytechnic State University, San Luis Obispo
Cumulative Shear In Vitro Model, Jared Olson, Alex Deppe, Braden Andrews
Biomedical Engineering
The purpose of our project is to find a reliable method of Subclinical Atherosclerosis detection by measuring the pressure drop across an artery. This model is intended to display how a pressure change correlates with arterial shear rate, and how a decrease in shear rate is ultimately related to atherosclerosis wherein early detection could prove life saving for millions of patients worldwide.
On-Body Pressure For Subcutaneous Infusion Of Drug,
2020
California Polytechnic State University, San Luis Obispo
On-Body Pressure For Subcutaneous Infusion Of Drug, Hannah Cole, Kayla Meacham, Eleanor Moran, Kaylee Voss
Biomedical Engineering
No abstract provided.
