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Suspected Blood Indicator To Identify Active Gastrointestinal Bleeding: A Prospective Validation, Samuel Han, Julien Fahed, David R. Cave 2018 University of Massachusetts Medical School

Suspected Blood Indicator To Identify Active Gastrointestinal Bleeding: A Prospective Validation, Samuel Han, Julien Fahed, David R. Cave

Open Access Articles

Background: The suspected blood indicator (SBI) function in the RAPID Reader v8.3 program was designed to quickly identify the presence of blood in video capsule endoscopy. While previous retrospective studies have shown that the SBI function was accurate in detecting the presence of active bleeding in the small bowel, its specificity and sensitivity were poor.

Methods: An initial retrospective review (phase 1) compared 115 patients with active gastrointestinal bleeding seen on video capsule endoscopy (VCE) to 115 patients with no active bleeding seen on VCE to produce a highly accurate algorithm. A prospective study (phase 2) was then performed ...


Motor Subtypes Of Parkinson’S Disease Can Be Identified By Frequency Component Of Postural Stability, Saba Rezvanian, Thurmon Lockhart, Christopher Frames, Rahul Soangra, Abraham Lieberman 2018 Arizona State University

Motor Subtypes Of Parkinson’S Disease Can Be Identified By Frequency Component Of Postural Stability, Saba Rezvanian, Thurmon Lockhart, Christopher Frames, Rahul Soangra, Abraham Lieberman

Physical Therapy Faculty Articles and Research

Parkinson’s disease (PD) can be divided into two subtypes based on clinical features—namely tremor dominant (TD) and postural instability and gait difficulty (PIGD). This categorization is important at the early stage of PD, since identifying the subtypes can help to predict the clinical progression of the disease. Accordingly, correctly diagnosing subtypes is critical in initiating appropriate early interventions and tracking the progression of the disease. However, as the disease progresses, it becomes increasingly difficult to further distinguish those attributes that are relevant to the subtypes. In this study, we investigated whether a method using the standing center of ...


Hyperpolarization Of Silicon Nanoparticles With Tempo Radicals, Jingzhe Hu, Nicholas Whiting, Pratip Bhattacharya 2018 University of Texas MD Anderson Cancer Center

Hyperpolarization Of Silicon Nanoparticles With Tempo Radicals, Jingzhe Hu, Nicholas Whiting, Pratip Bhattacharya

Nicholas Whiting

Silicon-based particles can be hyperpolarized via dynamic nuclear polarization to enhance 29Si magnetic resonance signals. Application of this technique to nanoscale silicon particles has been limited because of the low signal enhancements achieved; it is hypothesized that this is due to the low number of endogenous electronic defects inherent to the particles. We introduce a method of incorporating exogenous radicals into silicon nanoparticle suspensions in order to improve the hyperpolarization of 29Si nuclear spins to levels sufficient for in vivo MR imaging. Calibration of radical concentrations and polarization times are reported for a variety of silicon particle sizes (30−200 ...


Training Course In Focused Assessment With Sonography For Hiv/Tb In Hiv Prevalent Medical Centers In Malawi, Timothy Canan, Risa Hoffman, Alan Schooley, Zachary Boas, Kristin Schwab, Daniel Kahn, Roger Shih, Khumbo Phiri, Julie Parent, Ben Allan Banda, Ronald Chagoma, Chifundo Chipungu, Kara-Lee Pool 2018 University of California, Los Angeles

Training Course In Focused Assessment With Sonography For Hiv/Tb In Hiv Prevalent Medical Centers In Malawi, Timothy Canan, Risa Hoffman, Alan Schooley, Zachary Boas, Kristin Schwab, Daniel Kahn, Roger Shih, Khumbo Phiri, Julie Parent, Ben Allan Banda, Ronald Chagoma, Chifundo Chipungu, Kara-Lee Pool

Journal of Global Radiology

Purpose: This article describes the process of training medical providers of different backgrounds about the “focused assessment with sonography for HIV-associated TB” (FASH) exam to expand the availability of ultrasound for TB diagnosis in resource poor settings in the central region of Malawi.

Methods and Materials: A survey was completed by the 19 eligible participants before and after a 4-day training course regarding the utility of the FASH exam. A six-question quiz was used to assess knowledge of the use of ultrasound in the FASH exam before and after the course.

Results: Participants’ knowledge of the FASH technique significantly improved ...


Indicators For Prediction Of Mycobacterium Tuberculosis Positivity Detected With Bronchoalveolar Lavage Fluid, Xi Liu, Xing-Fang Hou, Lei Gao, Guo-Fang Deng, Ming-Xia Zhang, Qun-Yi Deng, Tao-Sheng Ye, Qian-Ting Yang, Bo-Ping Zhou, Zhi-Hua Wen, Hai-Ying Liu, Hardy Kornfeld, Xin-Chun Chen 2018 Shenzhen University

Indicators For Prediction Of Mycobacterium Tuberculosis Positivity Detected With Bronchoalveolar Lavage Fluid, Xi Liu, Xing-Fang Hou, Lei Gao, Guo-Fang Deng, Ming-Xia Zhang, Qun-Yi Deng, Tao-Sheng Ye, Qian-Ting Yang, Bo-Ping Zhou, Zhi-Hua Wen, Hai-Ying Liu, Hardy Kornfeld, Xin-Chun Chen

Open Access Articles

BACKGROUND: The diagnosis of active pulmonary tuberculosis (TB) remains a challenge in clinic, especially for sputum negative pulmonary TB. Bronchoalveolar lavage fluid (BALF) has higher sensitivity than sputum for detection of Mycobacterium tuberculosis (Mtb). However, bronchoscopy is invasive and costly, and not suitable for all patients. In order to make TB patients get more benefit from BALF for diagnosis, we explore which indicator might be used to optimize the choice of bronchoscopy.

METHODS: A total of 1539 sputum-smear-negative pulmonary TB suspects who underwent bronchoscopy were recruited for evaluation. The sensitivity, specificity and accuracy of Mtb detection in sputum and BALF ...


P16-Ki67-Hmb45 Immunohistochemical Profiling May Help Discriminate Between Spitzoid Melanoma And Atypical Spitz Nevi, Robert E. Garola, Vivekanand Singh 2018 Children's Mercy Hospital

P16-Ki67-Hmb45 Immunohistochemical Profiling May Help Discriminate Between Spitzoid Melanoma And Atypical Spitz Nevi, Robert E. Garola, Vivekanand Singh

Posters

Background

When Spitz nevi have increased vertical thickness (>1.5 MM), show ulceration and deep seated mitosis, the differential diagnostic considerations of atypical Spitz nevus (ASN) or a Spitzoid melanoma (SM) enter into consideration. While expert consultation from a dermatopathologist is most often sought to resolve the differential diagnosis, it could be expensive and time consuming. Recently, the use of molecular genetic testing has also been advocated in the work group up of atypical melanocytic proliferations. On the contrary, immunohistochemistry is a more routinely used technique in most pathology centers may be more simple to apply. A single immunohistochemical marker ...


A Delayed Diagnosis Of Tarsometatarsal Ligament (Lisfranc) Sprain In A Female College Soccer Athlete And Foot Rehabilitation, Boyoung Park 2018 University of Nebraska at Omaha

A Delayed Diagnosis Of Tarsometatarsal Ligament (Lisfranc) Sprain In A Female College Soccer Athlete And Foot Rehabilitation, Boyoung Park

Student Research and Creative Activity Fair

A Delayed Diagnosis of Tarsometatarsal Ligament (Lisfranc) Sprain in a Female College Soccer Athlete and Foot Rehabilitation

Park B*, Nicola M*, Wilkins S*: *University of Nebraska at Omaha, Omaha, NE

Objective: To emphasize the importance of the correct treatment protocol and the proper rehabilitation exercises based on the patient’s injury condition and healing process. Background: A 22-year-old female division I soccer athlete underwent tarsometatarsal ligament repair to stabilize midfoot. The patient started feeling pain in the dorsal aspect of her left 1st and 2nd metatarsals at the beginning of the season, however, she reported no specific mechanism of injury ...


The Development Of A Patient-Reported Outcome Measure For Assessment Of Genital Psoriasis Symptoms: The Genital Psoriasis Symptoms Scale (Gpss), Alice B. Gottlieb, Brian Kirby, Caitriona Ryan, April N. Naegeli, Russel Burge, Alison Potts Bleakman, Gil Yosipovitch 2018 New York Medical College

The Development Of A Patient-Reported Outcome Measure For Assessment Of Genital Psoriasis Symptoms: The Genital Psoriasis Symptoms Scale (Gpss), Alice B. Gottlieb, Brian Kirby, Caitriona Ryan, April N. Naegeli, Russel Burge, Alison Potts Bleakman, Gil Yosipovitch

NYMC Faculty Publications

INTRODUCTION: Patient-reported outcome measures (PROs) specific for genital psoriasis (GenPs) have not been described. METHODS: In this cross-sectional, qualitative study in patients with moderate-to-severe GenPs, we sought to develop a PRO useful for GenPs symptom assessment. A literature review was performed to identify relevant psoriasis or GenPs symptoms and existing PROs that may be useful in the evaluation of symptom severity in GenPs patients. The literature review findings were discussed with clinicians, and then patients with GenPs. RESULTS: Relevant psoriasis or GenPs symptoms from the literature review included itch, pain, scaling, redness/erythema, and stinging/burning. The validity of these ...


Female Autistic Perspectives: Limits In Diagnosis And Understanding, Alexandra Helmers 2018 The Graduate Center, City University of New York

Female Autistic Perspectives: Limits In Diagnosis And Understanding, Alexandra Helmers

All Dissertations, Theses, and Capstone Projects

The diagnosis of autism spectrum disorder has increased dramatically within the last two decades, with males being diagnosed, on average, four to five times more than females. Although researchers in the medical community have searched for a biological explanation for this discrepancy, no definitive cause has been found. I argue that our understanding of autism is primarily a social and cultural construction, in addition to a diagnosable medical disorder. The gender disparity in diagnosis reflects cultural narratives surrounding social interaction and the widespread belief in two distinct gender roles. Furthermore, narratives surrounding the topic of autism tend to unintentionally highlight ...


Purépecha Biohistory Project: A Differential Diagnosis On Burial 14.2 - A Possible Case Of Hypertrophic Osteoarthropathy, Eli Mrak 2018 Anthropology

Purépecha Biohistory Project: A Differential Diagnosis On Burial 14.2 - A Possible Case Of Hypertrophic Osteoarthropathy, Eli Mrak

Honors Theses AY 17/18

The well preserved skeletal remains of a young adult female from the pre-Hispanic city of Angamuco, Michoacán, Mexico were analyzed during the Purépecha Biohistory Project in May of 2016. The bones of this individual display an array of proliferative new bone formation (PNBF) in the form of extensive periosteal reaction to the majority of the elements present. A differential diagnosis was conducted based on the types of lesions present and their distribution on the individual’s skeleton. Osseous responses similar to that observed on this individual have been credited to a variety of diseases such as cardiovascular disease, gastrointestinal disease ...


Care Team Utilization Of The Gina Guidelines To Improve Quality Of Pediatric Asthma Care, Brandy Cloud 2018 University of Massachusetts Amherst

Care Team Utilization Of The Gina Guidelines To Improve Quality Of Pediatric Asthma Care, Brandy Cloud

Doctor of Nursing Practice (DNP) Projects

Purpose: Asthma is a chronic condition that affects millions of people, many of whom are children. There is a significant amount of evidence detailing best evidence step-by-step treatments based on severity, yet many children still have uncontrolled asthma. The comprehensive management of asthma is essential to improve health outcomes for children with asthma.

Methods: This project evaluated the implementation of the Global Initiative for Asthma (GINA) guidelines and assessed the barriers and facilitators present in a pediatric clinic which impact care delivery. This project Involved the implementation of an educational intervention based on the GINA guidelines to facilitate a team-based ...


Evaluating The Effectiveness Of Norton Cancer Institute’S Prompt Care Clinics, Stephanie L. Fred 2018 University of Kentucky

Evaluating The Effectiveness Of Norton Cancer Institute’S Prompt Care Clinics, Stephanie L. Fred

DNP Projects

Purpose: The purpose of this project was to evaluate outcomes of implementation of the Norton Cancer Institute (NCI) Prompt Care Clinics (PCCs), to include number of emergency room (ER) visits and number of inpatient admissions. A second purpose of the study was to identify presenting symptoms for patients seen in the NCI PCCs and compare the average charge per case for patients seen in the ER or NCI PCCs with the same diagnosis.

Methods: This study employed a pre-post implementation retrospective review of NCI patient electronic medical records (EPIC) to examine the effectiveness of the NCI PCCs on ER visits ...


The Impact Of The Nurse Practitioner In Pre-Admission Testing: A Comparative Review, Laurel A. Robinson 2018 University of Kentucky

The Impact Of The Nurse Practitioner In Pre-Admission Testing: A Comparative Review, Laurel A. Robinson

DNP Projects

Abstract

PURPOSE: The purpose of this study was to compare the efficiency of pre-admission testing (PAT) surgical clinic pre and post implementation of the APRN for patient assessment. Cancellation and delay occurrences for scheduled surgeries will be compared during two time periods on patients on the surgical schedule at Norton Women and Children’s Hospital (NWC).

METHODS: This study was a single-center, pre and post implementation retrospective comparative study of the impact of the NP led PAT unit at Norton Women and Children’s Hospital (NWC) in terms of delay and cancellation rates for day-of-surgery. The sample consisted of 411 ...


Brain Death: An Investigation Of Current Controversies, Meile Moore 2018 The University of Akron

Brain Death: An Investigation Of Current Controversies, Meile Moore

Williams Honors College, Honors Research Projects

Brain death is a highly debated and controversial topic spanning across several bodies of knowledge. Controversies of brain death include, but are not limited to, lack of consensus, false-positive diagnoses, residual function, public perception, and rights. Though brain death is often sensationalized by the media, distrust by the general population is warranted. The lack of consensus amongst professionals regarding brain death suggest that the American Academy of Neurology’s criterion must be revised. At the minimum, revising of the AAN criterion should focus on evolving ancillary testing, and establishing a minimum observation time before declaring death. Upon further clarification of ...


Resident Great Catches: Recognizing Resident Physicians Who Promote A Safe Environment For Patients, Kristin Streiler, Susamita Kesh 2018 Children's Mercy Hospital

Resident Great Catches: Recognizing Resident Physicians Who Promote A Safe Environment For Patients, Kristin Streiler, Susamita Kesh

Posters

No abstract provided.


Screening Techniques For Alzheimer's Disease, Christina Nicole Brooks 2018 University of North Dakota

Screening Techniques For Alzheimer's Disease, Christina Nicole Brooks

Physician Assistant Scholarly Project Posters

Alzheimer’s disease is a neurodegenerative disease that affects more than 55 million Americans. By the year 2050, experts project this disease will have increased three fold. Many screening techniques have been investigated to detect this disease early and begin treatment to slow its progression. The purpose of this study was to explore which medical modalities are the most effective for screening of Alzheimer’s disease. This literature review includes three databases, including PubMed, CINHAL, and Cochrane Database of Systematic Reviews. Topics that were researched include: cognitive screening tests, neuroimaging, laboratory diagnostic testing, DNA, and combined studies. Research was conducted ...


Screening Techniques For Alzheimer’S Disease, Christina Nicole Brooks 2018 University of North Dakota

Screening Techniques For Alzheimer’S Disease, Christina Nicole Brooks

Physician Assistant Scholarly Project Papers

Alzheimer’s disease is a neurodegenerative disease that affects more than 55 million Americans. By the year 2050, experts project this disease will have increased three fold. Many screening techniques have been investigated to detect this disease early and begin treatment to slow its progression. The purpose of this study was to explore which medical modalities are the most effective for screening of Alzheimer’s disease. This literature review includes three databases, including PubMed, CINHAL, and Cochrane Database of Systematic Reviews. Topics that were researched include: cognitive screening tests, neuroimaging, laboratory diagnostic testing, DNA, and combined studies. Research was conducted ...


Virtual Reality For The Characterization Of Blood Vessel To Airway Geometric Relationships, Mostafa Abdelraouf 2018 University of Iowa

Virtual Reality For The Characterization Of Blood Vessel To Airway Geometric Relationships, Mostafa Abdelraouf

Theses and Dissertations

An increase in the cross-sectional area (CSA) of the pulmonary arteries has been implicated in the progression of emphysema in COPD patients. Standardization of vessel size requires matching segments of the airway with their corresponding blood vessels. Automated matching is still error-prone, and manual matching by sifting through 2D slices is tedious and time-consuming. We propose a virtual reality (VR) system for the visualization of the airway and the vascular tree as a means of streamlining the verification of appropriate airway/vascular segment pairs selected for quantitation of arterial CSAs. In this work, we outline the technical specifications and design ...


Bow Hunter's Syndrome In A Patient With A Right Hypoplastic Vertebral Artery And A Dynamically Compressible Left Vertebral Artery, David Z. Cai, Ryan P. Roach, John P. Weaver, Gerald T. McGillicuddy, Zachary M. Mansell, Jonathan P. Eskander, Mark S. Eskander 2018 Tulane University

Bow Hunter's Syndrome In A Patient With A Right Hypoplastic Vertebral Artery And A Dynamically Compressible Left Vertebral Artery, David Z. Cai, Ryan P. Roach, John P. Weaver, Gerald T. Mcgillicuddy, Zachary M. Mansell, Jonathan P. Eskander, Mark S. Eskander

Open Access Articles

This is a case report of a 48-year-old man with multiple transient ischemic attacks and a known hypoplastic right vertebral artery (VA) who presented after a syncopal event while turning his head to the left. The objective of this study is to demonstrate the necessity of proper diagnosis and management of cerebrovascular pathology including imaging and surgical intervention in patients with known anatomical anomalies. This study was conducted at Massachusetts, United States of America. Our patient's history was significant for a hypoplastic right VA and a stenotic segment of the right VA at the C3-C4 junction. There was also ...


Usefulness Of The Captia Syphilis Igg Eia Test Method And Reverse Algorithm For Detection Of Syphilis Infection In A Public Health Setting, Patricia Armour 2018 Virginia Commonwealth University

Usefulness Of The Captia Syphilis Igg Eia Test Method And Reverse Algorithm For Detection Of Syphilis Infection In A Public Health Setting, Patricia Armour

Theses and Dissertations

Syphilis, a systemic sexually transmitted disease, is on the rise in the US, with infection rates the highest recorded since 1994 according to the CDC. Useful laboratory testing is an important diagnostic tool for determining individual syphilis infection and preventing community-wide disease spread.

The purpose of this study was to determine the usefulness of a specific automated treponemal test method, the CaptiaTM Syphilis IgG EIA, and the syphilis reverse algorithm interpretation for detecting syphilis infection among patients seeking care in a public health clinic. The study employed a retrospective, nonexperimental descriptive correlational design with data collected between 2012-2013 from ...


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