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Articles 31 - 60 of 433
Full-Text Articles in Medicine and Health Sciences
Adiponectin Levels Decrease Independently Of Body Mass Index And Diabetes Type Afterthe Normalization Of Hyperglycemia, Nalan Meti̇n Aksu, Duygu Yazgan Aksoy, Meltem Akkaş, Neşe Çinar, Fatma Uçar, Okan Bülent Yildiz, Aydan Usman
Adiponectin Levels Decrease Independently Of Body Mass Index And Diabetes Type Afterthe Normalization Of Hyperglycemia, Nalan Meti̇n Aksu, Duygu Yazgan Aksoy, Meltem Akkaş, Neşe Çinar, Fatma Uçar, Okan Bülent Yildiz, Aydan Usman
Turkish Journal of Medical Sciences
Background/aim: Acute hyperglycemia is generally a frequently encountered condition in the emergency department (ED), because it is seen as a complication of diabetes mellitus (DM). In this study, we aimed to detect the change in adiponectin levels during acute hyperglycemic states and after normalization of blood glucose with insulin treatment. Materials and methods: Forty-eight patients over the age of 18 years who were admitted to the ED with acute hyperglycemia were included in the study. Serum samples were taken from patients on admission and 6 h after the normalization of blood glucose with insulin treatment, and adiponectin levels were measured …
Correlation Of Serum Fatty Acid Binding Protein-4 And Interleukin-6 With Airflowlimitation And Quality Of Life In Stable And Acute Exacerbation Of Copd, Mohammad Reza Aslani, Zeynab Ghazaei, Hassan Ghobadi
Correlation Of Serum Fatty Acid Binding Protein-4 And Interleukin-6 With Airflowlimitation And Quality Of Life In Stable And Acute Exacerbation Of Copd, Mohammad Reza Aslani, Zeynab Ghazaei, Hassan Ghobadi
Turkish Journal of Medical Sciences
Background/aim: The serum fatty acid binding protein 4 (FABP-4) level increases in chronic inflammatory diseases. The present study aimed to examine serum FABP-4 and interleukin (IL)-6 levels in patients with stable and acute exacerbation of chronic obstructive pulmonary disease (COPD) and the correlation of these markers with airflow limitation. Materials and methods: We measured serum FABP-4 and IL-6 levels in 60 COPD patients [30 stable COPD (SCOPD), and 30 acute exacerbation of COPD (AECOPD)], and 30 healthy subjects and compared them with airflow limitation according to the COPD stage in the Global Initiative for Chronic Obstructive Pulmonary Disease (GOLD) criteria, …
Efficacy Of Hijamat (Wet Cupping Therapy) In Iranian Patients With Nonalcoholic Fattyliver Disease: A Controlled Clinical Trial, Homayoon Bashiri, Arezoo Bozorgomid, Vahid Shojaeimotlagh
Efficacy Of Hijamat (Wet Cupping Therapy) In Iranian Patients With Nonalcoholic Fattyliver Disease: A Controlled Clinical Trial, Homayoon Bashiri, Arezoo Bozorgomid, Vahid Shojaeimotlagh
Turkish Journal of Medical Sciences
Background/aim: Nonalcoholic fatty liver disease (NAFLD) is known to be the most prevalent chronic liver disease all over the world. The incidence of this disease has dramatically increased during the last decade. Studies have shown a strong relationship between the level of ferritin and the severity of NAFLD. The objective of the present study was to assess the effect of adding Hijamat, as an iron reducing procedure, to standard lifestyle modification on the improvement of insulin resistance and liver enzymes in patients with NAFLD. Materials and methods: One hundred and twenty NAFLD patients participated in a randomized, controlled, single-blind trial …
Prognostic Role Of Homeostasis Model Assessment And Oral Glucose Tolerance Test Innondiabetic Patients With Bell's Palsy, Tuğba Karagöz, Ömer Bayir, Emel Çadalli Tatar, Erman Çakal, Ali̇ Özdek, Kemal Keseroğlu, Mustafa Şahi̇n, Mehmet Hakan Korkmaz
Prognostic Role Of Homeostasis Model Assessment And Oral Glucose Tolerance Test Innondiabetic Patients With Bell's Palsy, Tuğba Karagöz, Ömer Bayir, Emel Çadalli Tatar, Erman Çakal, Ali̇ Özdek, Kemal Keseroğlu, Mustafa Şahi̇n, Mehmet Hakan Korkmaz
Turkish Journal of Medical Sciences
Background/aim: We aimed to reveal the incidence and predictive role of insulin resistance and distorted oral glucose tolerance test in nondiabetic patients with Bell's Palsy (BP). Materials and methods: Eighty-six patients with BP and 28 control subjects; all with normal blood glucose levels and no history of diabetes, were enrolled in the study. We investigated insulin resistance (IR) in all subjects, in terms of HOMA-IR greater than 2.7. Sixtytwo of the patients also underwent an oral glucose tolerance test (OGTT). Results: The mean HOMA-IR value was significantly increased in patients, compared to the control group (3.2 vs 1.6; P < 0.01). IR was detected more in BP patients than in controls (P < 0.05). The patients with higher HOMA-IR values had more severe facial dysfunction at the initial presentation and complete recovery time took longer than the patients with normal HOMA-IR value (75 days vs 42 days; P < 0.05). Following a 2h-OGTT, impaired glucose tolerance and newly diagnosed DM were found in 60% of the patients. Recovery time was significantly longer in prediabetics and newly diagnosed diabetic patients than in patients with normal glycemia (68 days, 52 days, and 32 days, respectively; P < 0.01). Conclusion: There is a strong linkage between HOMA-IR value and BP prognosis so HOMA-IR value may have a significant role of predicting BP prognosis at presentation.
Efficacy Of Mepolizumab Treatment In Oral Corticosteroid-Dependent Severe Eosinophilicasthma Patients With Chronic Rhinosinusitis With Nasal Polyps: Single Center, Real Life Study, İnsu Yilmaz, Murat Türk, Saki̇ne Nazi̇k Bahçeci̇oğlu, Nuri̇ Tutar, İnci̇ Gülmez
Efficacy Of Mepolizumab Treatment In Oral Corticosteroid-Dependent Severe Eosinophilicasthma Patients With Chronic Rhinosinusitis With Nasal Polyps: Single Center, Real Life Study, İnsu Yilmaz, Murat Türk, Saki̇ne Nazi̇k Bahçeci̇oğlu, Nuri̇ Tutar, İnci̇ Gülmez
Turkish Journal of Medical Sciences
Background/aim: Oral corticosteroid (OCS)-dependent severe eosinophilic asthma with chronic rhinosinusitis with nasal polyps (SEACRSwNP) would be a suitable phenotype for mepolizumab treatment. This study evaluated the short-term efficacy of mepolizumab treatment in OCS-dependent SEA-CRSwNP. Materials and methods: Baseline and 24th week results [daily OCS doses, asthma exacerbation frequency, asthma control test (ACT) scores, blood eosinophil levels, FEV1 values, and numerical analog scale (NAS) of CRSwNP symptoms] of patients who were treated for at least 24 weeks with mepolizumab were retrospectively evaluated and compared. Results: A total of 16 patients were enrolled in the study. Mepolizumab was discontinued in one patient …
The Validity And Reliability Of The Turkish Version Of The Body Esteem Scale Foradolescents And Adults (Besaa) For Children, Umut Ece Arslan, Lütfi̇ye Hi̇lal Özcebe, Hande Konşuk Ünlü, Sarp Üner, Mahmut Saadi̇ Yardim, Ozgur Araz, Terry T-K Huang
The Validity And Reliability Of The Turkish Version Of The Body Esteem Scale Foradolescents And Adults (Besaa) For Children, Umut Ece Arslan, Lütfi̇ye Hi̇lal Özcebe, Hande Konşuk Ünlü, Sarp Üner, Mahmut Saadi̇ Yardim, Ozgur Araz, Terry T-K Huang
Turkish Journal of Medical Sciences
Background/aim: Body esteem (BE) is defined as the self-evaluation of one's own body or appearance. The Body Esteem Scale for Adolescents and Adults (BESAA) consists of three subscales: BE-appearance, BE-weight, and BE-attribution. Though initially developed for adolescents and adults, the use of the scale has recently increased in health-related research on children. This study aimed to assess the validity and reliability of the Turkish version of the BESAA for children. Materials and methods: The participants in the study were 4th grade children (aged 9-10 years) in Ankara, Turkey. The validity of the scale was evaluated through exploratory and confirmatory factor …
The Usual Course Of Thorax Ct Findings Of Covid-19 Infection Andwhen To Perform Control Thorax Ct Scan, Yasemi̇n Gündüz, Mehmet Hali̇l Öztürk, Yakup Tomak
The Usual Course Of Thorax Ct Findings Of Covid-19 Infection Andwhen To Perform Control Thorax Ct Scan, Yasemi̇n Gündüz, Mehmet Hali̇l Öztürk, Yakup Tomak
Turkish Journal of Medical Sciences
: COVID-19 infection, a highly contagious disease caused by the SARS-CoV virus, and the World Health Organization declared this increasingly spreading disease as a global public health emergency (pandemic). In the diagnosis of COVID-19, the polymerase chain reaction (RT-PCR) is considered as the reference standard test. In the early stages, thorax CT findings could be present even before the onset of symptoms, thorax CT has quite high sensitivity in COVID-19 patients with false negative RT-PCR results, and it has a great importance not only in diagnosis but also in follow up. We think that it might be beneficial for our …
Opium And Risk Of Gastrointestinal Cancer: A Case-Control Study, Reza Vazirinejad, Roya Najafipour, Mohsen Rezaeian, Alireza Ghazizadeh, Fateme Doost Mohammadi
Opium And Risk Of Gastrointestinal Cancer: A Case-Control Study, Reza Vazirinejad, Roya Najafipour, Mohsen Rezaeian, Alireza Ghazizadeh, Fateme Doost Mohammadi
Turkish Journal of Medical Sciences
Background/aim: Gastrointestinal (GI) cancers are among the most common cancers in the world. Many risk factors may increase the chance of developing GI cancers. In recent years, a number of epidemiological studies have reported evidence of carcinogenic effects of opium in humans. This study aimed to investigate the relationship between opium use and GI cancer. Materials and methods: This case-control study was performed on 95 patients with GI cancer and 190 healthy individuals (matched for age, sex, place of residence, and smoking) in Rafsanjan, Iran, in 2018. Diet information, as well as history of smoking, the use of hookah, opium, …
Which Bayley-Iii Cut-Off Values Should Be Used In Different Developmental Levels?, Peli̇n Çeli̇k, İclal Ayranci Sucakli, Hali̇l İbrahi̇m Yakut
Which Bayley-Iii Cut-Off Values Should Be Used In Different Developmental Levels?, Peli̇n Çeli̇k, İclal Ayranci Sucakli, Hali̇l İbrahi̇m Yakut
Turkish Journal of Medical Sciences
Background/aim: Latest version of Bayley Scales (Bayley-III) and its predecessor (BSID-II) are the most widely used standardized developmental tools in infancy and early childhood. Recent studies showed that Bayley-III scores were higher than BSID-II in 18-24 month-old and mostly premature infants. We aimed to evaluate the generalization of inflated scores of Bayley-III to children aged 6-42 months with different disease groups, and to find out which cut-off points should be used in Bayley-III to detect mild, moderate, and severe developmental delay according to BSID-II standard cut-off points. Materials and methods: Two hundred and fifty-five children aged 6-42 months with different …
Relationship Between Helicobacter Pylori Infection And Pityriasis Versicolor:Can Helicobacter Pylori Infection Be A New Etiologic Factor For Pityriasis Versicolor?, Ömer Kutlu, Zeynal Doğan, Hati̇ce Meral Ekşi̇oğlu, Murat Keki̇lli̇
Relationship Between Helicobacter Pylori Infection And Pityriasis Versicolor:Can Helicobacter Pylori Infection Be A New Etiologic Factor For Pityriasis Versicolor?, Ömer Kutlu, Zeynal Doğan, Hati̇ce Meral Ekşi̇oğlu, Murat Keki̇lli̇
Turkish Journal of Medical Sciences
Background/aim: H. pylori has been found to be related to certain dermatological diseases. However, there is no data as yet to propose an association between H. pylori and pityriasis versicolor. In this study, we aimed to evaluate the association between H. pylori and pityriasis versicolor. Materials and methods: This was a prospective study performed in the Gastroenterology and Dermatology and Venereology departments of the Health Sciences University, Ankara Training and Research Centre. A total of 57 consecutive patients (27 pityriasis versicolor, 30 telogen effluvium) were enrolled from the Department of Dermatology and Venereology. All patients were screened for H. pylori …
Mean Platelet Volume And Response To The First Line Therapy In Newly Diagnosed Adultimmune Thrombocytopenia Patients: A Retrospective Study, Erman Akkuş, Çi̇ğdem Fi̇dan, Gülşah Demi̇rci̇, Ali̇ Aytuğ Kuştaş, Meltem Yüksel
Mean Platelet Volume And Response To The First Line Therapy In Newly Diagnosed Adultimmune Thrombocytopenia Patients: A Retrospective Study, Erman Akkuş, Çi̇ğdem Fi̇dan, Gülşah Demi̇rci̇, Ali̇ Aytuğ Kuştaş, Meltem Yüksel
Turkish Journal of Medical Sciences
Background/aim: Immune thrombocytopenia (ITP) is treated by corticosteroids and/or intravenous immune globulin as the first line treatment when necessary. Mean platelet volume (MPV) is a marker of platelet production and function. In this study, we aimed to search the relationship between the MPV and the treatment response in ITP patients and it was hypothesized that MPV can be used as a predictor of the response. Materials and methods: The 70 newly diagnosed adult primary ITP patients and 70 of healthy people were included. MPV between ITP and healthy population, MPV in the diagnosis and after the treatment between the responders …
Thiol/Disulphide Homeostasis In Intensive Care Unit Patients With Sepsis And Septic Shock, Hami̇t Yildiz
Thiol/Disulphide Homeostasis In Intensive Care Unit Patients With Sepsis And Septic Shock, Hami̇t Yildiz
Turkish Journal of Medical Sciences
Background/aim: Sepsis is a condition caused by infection followed by unregulated inflammatory response which may lead to organ dysfunction. The aim of this study is to be the first in the literature and it has been designed to show the thiol/disulphide changes in patients with sepsis and septic shock and their correlation with acute phase reactants. Material and methods: A total of 113 patients (septic shock 53 and sepsis 60) and 60 healthy control subjects have been enrolled in this study from the period February 2018 to 2019. The patients were divided in 2 groups: nonsurvivors (74) and survivors (39). …
The Assessment Of Skin Sebum And Moisture Content Of Infants With Atopic Dermatitis, Hati̇ce Güneş, Hülya Nazi̇k, Mehmet Yaşar Özkars, Nurgül Parlak, Ayten Yildiz, Ömer Duyuran, Bahaüddi̇n Ahmed Yalçin
The Assessment Of Skin Sebum And Moisture Content Of Infants With Atopic Dermatitis, Hati̇ce Güneş, Hülya Nazi̇k, Mehmet Yaşar Özkars, Nurgül Parlak, Ayten Yildiz, Ömer Duyuran, Bahaüddi̇n Ahmed Yalçin
Turkish Journal of Medical Sciences
Background/aim: Atopic dermatitis (AD) is a chronic, inflammatory skin disorder characterized by dry skin, pruritus and eczematous lesions. The aim of this study is to evaluate the skin moisture and sebum content of the infants with AD and its relationship between the disease severity. Materials and methods: For this cross-sectional and case-control study we included 49 infants with AD aged between 2 and 24 months and 34 healthy infants with the same age and sex as a control group. Skin moisture and sebum content were measured by the bio- impedance method and recorded. Skin prick tests, total IgE levels and …
The Association Between The Route Of Nutrition And Serum Levels Of Adipokines In Critical Illness: A Pilot Study, Kürşat Gündoğan, Ender Doğan, Nurhayat Tuğra Özer, Gülşah Güneş Şahi̇n, Serap Şahi̇n, Murat Sungur, İsmai̇l Hakki Akbudak, Sabahatti̇n Muhtaroğlu, Muhammet Güven, Thomas R. Ziegler
The Association Between The Route Of Nutrition And Serum Levels Of Adipokines In Critical Illness: A Pilot Study, Kürşat Gündoğan, Ender Doğan, Nurhayat Tuğra Özer, Gülşah Güneş Şahi̇n, Serap Şahi̇n, Murat Sungur, İsmai̇l Hakki Akbudak, Sabahatti̇n Muhtaroğlu, Muhammet Güven, Thomas R. Ziegler
Turkish Journal of Medical Sciences
Background/aim: Adipokines play an important role in the regulation of metabolism. In critical illness, they alter serum levels and are suspected to worsen clinical outcomes. But the effect of the route of nutrition on adipokines is not known. The purpose of this study was to evaluate the association between the route of nutrition and adipokine levels in critically ill patients. Materials and methods: This prospective study was performed in an intensive care unit (ICU). Patients admitted to the ICU for least 72 h and receiving either enteral nutrition (EN) via tube feeding or parenteral nutrition (PN) were enrolled. Serum was …
Clinical Evaluation Of Pituitary Insufficiency In Adult Population, Selvi̇han Beysel, Mustafa Çalişkan, Muhammed Kizilgül, Seyfullah Kan, Mustafa Özbek, Erman Çakal
Clinical Evaluation Of Pituitary Insufficiency In Adult Population, Selvi̇han Beysel, Mustafa Çalişkan, Muhammed Kizilgül, Seyfullah Kan, Mustafa Özbek, Erman Çakal
Turkish Journal of Medical Sciences
Background/aim: This retrospective study aimed to investigate the clinical profile of pituitary insufficiency (PI) in adult population. Materials and methods: One hundred and fifty patients who were diagnosed as having PI between 2012 and 2018 (53.3% female, mean age 48.13 ± 15.83 years) were retrospectively analyzed. Results: Age at diagnosis was higher in females as compared with males (51.13 ± 15.95 vs. 44.70 ± 15.08 years, P = 0.012). The most frequent presenting signs were headache (29.4%) and visual disturbance (19.6%) in general. Females frequently presented with headache (33.3%), whereas males presented with sexual dysfunction (34.4%). The most frequent cause …
Evaluation Of The Cardioprotective Effects Of Crystalloid Del Nido Cardioplegia Solution Via A Rapid And Accurate Cardiac Marker: Heart-Type Fatty Acid-Binding Protein, Mehmet Ki̇ri̇şci̇, Aydemi̇r Koçarslan, Duygun Altintaş Aykan, Fi̇li̇z Alkan Baylan, Adem Doğaner, Yavuz Orak
Evaluation Of The Cardioprotective Effects Of Crystalloid Del Nido Cardioplegia Solution Via A Rapid And Accurate Cardiac Marker: Heart-Type Fatty Acid-Binding Protein, Mehmet Ki̇ri̇şci̇, Aydemi̇r Koçarslan, Duygun Altintaş Aykan, Fi̇li̇z Alkan Baylan, Adem Doğaner, Yavuz Orak
Turkish Journal of Medical Sciences
Background/aim: Our aim in this study was to compare the efficacy and safety of crystalloid del Nido solution and cold blood cardioplegia solution on clinical and laboratory parameters. Materials and methods: Sixty patients who underwent elective coronary bypass operation between July 2019 and January 2020 were included in our study. Patients were divided into 2 groups of 30 patients using del Nido solution (DNS) and cold blood cardioplegia solution (CBCS), which were given for cardiac arrest. Demographic data, preoperative, postoperative 0th h, 6th h and 4th day creatine kinase myocardial band (CK-MB) and troponin I values were compared with a …
Spectrum Of Germline Cancer Susceptibility Gene Mutations In Turkish Colorectal Cancer Patients: A Single Center Study, Haktan Bağiş Erdem, Taha Bahsi̇
Spectrum Of Germline Cancer Susceptibility Gene Mutations In Turkish Colorectal Cancer Patients: A Single Center Study, Haktan Bağiş Erdem, Taha Bahsi̇
Turkish Journal of Medical Sciences
Background/aim: Quarter of colorectal cancer patients have a family history and 6% of these comprise hereditary cancer syndromes. For developing national health strategies for genetic screening, it is crucial to determine the spectrum of damaging alterations in causative genes and to describe frequent founder mutations. Materials and methods: One hundred and thirty six unrelated colorectal cancer cases were investigated. Qiagen large hereditary cancer panel and Hereditary Cancer Solution v1.1 panel were used for sequencing. The sequencing process was performed on the Illumina MiSeq system. The data analyses were performed on QIAGEN Clinical Insight (QCITM) Analyze software and Sophia DDM software. …
Posterior Fossa Horns; A New Calvarial Finding Of Mucopolysaccharidoses With Well-Known Cranial Mri Features, Çağri Damar, Betül Emi̇ne Deri̇nkuyu, Muazzez Asburçe Bi̇ke Olgaç Kiliçkaya, Mehmet Öztürk, Çi̇ğdem Öztunali, Ayşe Gül Alimli, Öznur Leman Boyunaga, Murat Uçar, Fati̇h Süheyl Ezgü, Leyla Tümer, Alp Özgün Börcek, Ahmet Siğirci
Posterior Fossa Horns; A New Calvarial Finding Of Mucopolysaccharidoses With Well-Known Cranial Mri Features, Çağri Damar, Betül Emi̇ne Deri̇nkuyu, Muazzez Asburçe Bi̇ke Olgaç Kiliçkaya, Mehmet Öztürk, Çi̇ğdem Öztunali, Ayşe Gül Alimli, Öznur Leman Boyunaga, Murat Uçar, Fati̇h Süheyl Ezgü, Leyla Tümer, Alp Özgün Börcek, Ahmet Siğirci
Turkish Journal of Medical Sciences
Background/aim: Mucopolysaccharidoses (MPS) are a group of hereditary metabolic diseases. The aim of this study was to share the previously unreported calvarial finding of internal hypertrophy of the occipitomastoid sutures (IHOMS) together with some other well- known cranial MRI findings in this patient series. Materials and methods: A retrospective evaluation was conducted of 80 cranial MRIs of patients who had been diagnosed and followed up with MPS from 2008 to 2019 in our center. Of these patients, 11 had Hurler, 14 had Hunter, 24 had Sanfilippo, 15 had Morquio, 14 had Maroteaux-Lamy, and 2 had Sly disease. The cranial MRIs …
Analysing The Blood-Stemming Effect Of Ankaferd Blood Stopper In Medulla Spinalis Surgery, Dursun Turkoz, Cem Demi̇rel, Hüseyi̇n Sataloğlu, Cengiz Cokluk
Analysing The Blood-Stemming Effect Of Ankaferd Blood Stopper In Medulla Spinalis Surgery, Dursun Turkoz, Cem Demi̇rel, Hüseyi̇n Sataloğlu, Cengiz Cokluk
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to investigate the possible toxicity of the Ankaferd Blood Stopper (ABS) on the neural system. Materials and methods: Thirty Sprague Dawley rats were randomized into ABS (n: 15) and control (n: 15) groups. Following the anaesthetic induction, total laminectomy was performed to the lower thoracic, and upper lumbar areas in both groups and medulla spinalis was exposed. Two myelotomies were performed on the medulla spinalis. One millilitre ABS was applied to the incision site in the ABS group, and one millilitre 0.9% saline solution was applied in the control group. Rats were observed …
Reply To Letter To The Editor, Zehra İpek Arslan Aydin
Reply To Letter To The Editor, Zehra İpek Arslan Aydin
Turkish Journal of Medical Sciences
No abstract provided.
The Effect Of Baicalein On Wnt/Ss-Catenin Pathway And Mir-25 Expression In Saos-2 Osteosarcoma Cell Line, Esra Örenli̇li̇ Yaylagül, Celal Ülger
The Effect Of Baicalein On Wnt/Ss-Catenin Pathway And Mir-25 Expression In Saos-2 Osteosarcoma Cell Line, Esra Örenli̇li̇ Yaylagül, Celal Ülger
Turkish Journal of Medical Sciences
Background/aim: Osteosarcoma is the most common primary bone malignancy that occurs frequently in children and adolescents. Baicalein, a flavonoid that has attracted great attention in recent years with its strong antitumor activity, shows a wide range of biological and pharmaceutical effects.MicroRNAs have been found to be involved in many critical processes in cancers. This study aimed to investigate the effect of baicalein and miR-25 on Wnt/ß-catenin signaling pathway of osteosarcoma cell line Saos-2. Materials and methods: Cell viability was assessed, and qRT-PCR and Western blot were performed to study the effects of baicalein on expression of Wnt/ß-catenin signaling pathway-realted genes …
Effect Of Sugammadex On Chest Radiographic Abnormality In The Early Postoperative Period After Video-Assisted Thoracoscopic Lobectomy, Dong Kyu Lee, Sung Wook Kang, Hyun Koo Kim, Hyo Sung Kim, Heezoo Kim
Effect Of Sugammadex On Chest Radiographic Abnormality In The Early Postoperative Period After Video-Assisted Thoracoscopic Lobectomy, Dong Kyu Lee, Sung Wook Kang, Hyun Koo Kim, Hyo Sung Kim, Heezoo Kim
Turkish Journal of Medical Sciences
Background/aim: Sugammadex, which offsets the effects of neuromuscular blocking agents (NMBs), has advantages over traditional reversal agents like pyridostigmine, as it enables fast and reliable recovery from neuromuscular blockade. This study compared the incidence of early postoperative chest radiographic abnormalities (CRA) between sugammadex (group S) and pyridostigmine (group P) following video-assisted thoracoscopic (VAT) lobectomy for lung cancer.Materials and methods: We performed a retrospective cohort analysis by reviewing the medical records of patients who underwent VAT lobectomy at a single university medical center. We defined the early postoperative CRA as a characteristic appearance on chest radiograph up to 2 days after …
Alterations In Follicular Fluid Bmp-15 Rna Expression In Women Undergoing Controlled Ovarian Hyperstimulation, Şükri̇ye Derya Deveci̇
Alterations In Follicular Fluid Bmp-15 Rna Expression In Women Undergoing Controlled Ovarian Hyperstimulation, Şükri̇ye Derya Deveci̇
Turkish Journal of Medical Sciences
Background/aim: Bone morphogenetic protein-15 (BMP-15) is one of the maturation indicators of the ovarian follicular pool. The aim of this study was to investigate the possible difference of follicular fluid (FF) BMP-15 RNA expression among low, normal, and high responder women attending controlled ovarian hyperstimulation-intracytoplasmic sperm injection (COH-ICSI) cycles.Materials and methods: This cross-sectional study was conducted with 75 FFs of COH-ICSI cycles performed at the IVF Unit of University Hospital. Twenty FF from low response (group 1), 27 FF from normal response (group 2), and 28 FF from high response (group 3) were recruited for the study between September 2014 …
Baseline Characteristics Predicting Clinical Outcomes And Serious Adverse Events In Middle-Aged Hypertensive Women: A Subanalysis Of The Sprint In Women Aged, Volkan Aydin, Ahmet Akici, Si̇bel Sakarya, Mehmet Akman, Ali̇ Serdar Fak
Baseline Characteristics Predicting Clinical Outcomes And Serious Adverse Events In Middle-Aged Hypertensive Women: A Subanalysis Of The Sprint In Women Aged, Volkan Aydin, Ahmet Akici, Si̇bel Sakarya, Mehmet Akman, Ali̇ Serdar Fak
Turkish Journal of Medical Sciences
Background/aim: The predictability of clinical outcomes in hypertension in specific patient groups, especially underrepresented populations is the key to rational treatment. This study aimed to investigate the impact of baseline characteristics of
Association Between Monocyte To High-Density Lipoprotein Cholesterol Ratio And Bicuspid Aortic Valve Degeneration, Bi̇lge Duran Karaduman, Hüseyi̇n Ayhan, Telat Keleş, Engi̇n Bozkurt
Association Between Monocyte To High-Density Lipoprotein Cholesterol Ratio And Bicuspid Aortic Valve Degeneration, Bi̇lge Duran Karaduman, Hüseyi̇n Ayhan, Telat Keleş, Engi̇n Bozkurt
Turkish Journal of Medical Sciences
Background/aim: From a pathophysiological point of view, inflammation is thought to be more dominant in bicuspid aortic valve (BAV) stenosis than tricuspid aortic valve (TAV) stenosis. Our study aimed to determine the association between monocyte to high-density lipoprotein cholesterol (HDL-C) ratio (MHR), a new inflammatory marker, and the speed of progression of stenosis and pathophysiology of BAV stenosis.Materials and methods: A total of 210 severe aortic stenosis patients (70 consecutive BAV patients, 140 matched TAV patients) were retrospectively enrolled in the study. Clinical and echocardiographic data and laboratory results related to our research were collected retrospectively from the patients' records. …
He Utility Of Synovial Fluid Levels Of Adamts9 And Adamts4 In Predicting Treatment Responses To Intraarticular Steroid Injections In Patients With Knee Osteoarthritis, Kenan Özler
Turkish Journal of Medical Sciences
Background/aim: This study aims to identify the role of synovial fluid levels of a disintegrin and metalloproteinase with thrombospondin motifs 9 (ADAMTS9) and a disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAMTS4) for the prediction of intraarticular steroid injection success in knee osteoarthritis (OA).Material and methods: A total of eighty-four advanced stage knee OA patients (42 with stage 3 OA and 42 with stage 4 OA) were enrolled in the study. Baseline and posttreatment outcomes were determined using Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). Pretreatment synovial fluid ADAMTS9 and ADAMTS4 levels were measured by enzyme linked immunosorbent assay …
Posttraumatic Growth And Death Anxiety In Caregivers Of Cancer Patients: Phoenix Study, Ali̇ Alkan, Eli̇f Berna Köksoy, Ebru Karci, Asli Alkan, Eduardo Bruera, Fi̇li̇z Çay Şenler
Posttraumatic Growth And Death Anxiety In Caregivers Of Cancer Patients: Phoenix Study, Ali̇ Alkan, Eli̇f Berna Köksoy, Ebru Karci, Asli Alkan, Eduardo Bruera, Fi̇li̇z Çay Şenler
Turkish Journal of Medical Sciences
Background/aim: Posttraumatic growth (PTG) is defined as positive psychological changes following a challenging or traumatic life event. The purpose of this study is to define the predictors of PTG and death anxiety (DAN) in caregivers of cancer patients and evaluate the impact of DAN on PTG.Materials and methods: The caregivers of cancer patients were evaluated using structured questionnaires, including a validated PTG scale and Templer death anxiety scale.Results: In 3 different cancer centers, 426 participants were evaluated. In multivariate analysis of factors associated with PTG, a high DAN score was the only parameter associated with high PTG scores [OR: 1.6, …
Antiinfective And Wound-Healing Pleiotropic Actions Of Ankaferd Hemostat, İbrahi̇m Celaletti̇n Haznedaroğlu, Mustafa Çelebi̇er
Antiinfective And Wound-Healing Pleiotropic Actions Of Ankaferd Hemostat, İbrahi̇m Celaletti̇n Haznedaroğlu, Mustafa Çelebi̇er
Turkish Journal of Medical Sciences
To the Editor,We read with great interest the article entitled "An evaluation of the effects of caffeic acid phenethyl ester and Ankaferd blood stopper on secondary wound healing of oral mucosal tissue", published recently in the Journal[1]. The authors indicated that Ankaferd Hemostat (Ankaferd Blood Stopper, ABS) and caffeic acid phenethyl ester had positive effects on the oral wound healing process. Since ABS has already been used in dental surgery for years, it is known as not irritable to the oral mucosa [2]. ABS antibacterial, antiinfective, and cellular features are also established [3]. More importantly, ABS is clinically effective in …
Radiological Approaches To Covid-19 Pneumonia, Furkan Ufuk, Recep Savaş, Tuncay Hazirolan
Radiological Approaches To Covid-19 Pneumonia, Furkan Ufuk, Recep Savaş, Tuncay Hazirolan
Turkish Journal of Medical Sciences
No abstract provided.
Influence Of Aluminum Salts On Covid-19 Infected Patients, Ali̇ Demi̇r, İbrahi̇m Erayman, Oğuz Doğan, Murat Keki̇lli̇
Influence Of Aluminum Salts On Covid-19 Infected Patients, Ali̇ Demi̇r, İbrahi̇m Erayman, Oğuz Doğan, Murat Keki̇lli̇
Turkish Journal of Medical Sciences
Background/aim: Based on the antiviral and antibacterial properties of aluminum salts, we aimed to find out the influence of aluminum salts on COVID-19 infected patients. Materials and methods: We performed an observational retrospective cohort study which includes the patients diagnosed as COVID-19 and received aluminum salts in addition to actual treatments during hospitalization as the treatment group (Alum Group). Patients who received standard COVID-19 treatment protocols in the Infectious Diseases Clinics were included as the Control Group. Clinical findings, laboratory parameters, length of stay, survival, radiological follow-up, intensive care and mechanical ventilation needs, the presence of comorbidity, polymerase chain reaction …